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The map label for this gene is appC [H]

Identifier: 160902777

GI number: 160902777

Start: 1427241

End: 1428632

Strand: Direct

Name: appC [H]

Synonym: Pmob_1331

Alternate gene names: 160902777

Gene position: 1427241-1428632 (Clockwise)

Preceding gene: 160902776

Following gene: 160902778

Centisome position: 65.79

GC content: 36.78

Gene sequence:

>1392_bases
GTGAATAAAACAAATCGTGTTGCCAAGCAATTAAAAGATTTTTGGGATGAGTTTAAGCAAGTTAAATTTGGTATAGCTGG
TATAATTCTTTTAATCCTTTTTGTAATTTTAGTGGTTTTTGAACAATTTTTAATCCCATTTCCTGAAGCTTCTACAAGGT
GGAGGGATATTACCTATTGGGAAGATAACCCTCGAAGCGTTCCCCCTGTTTGGATAAATTGGTTTTCTCAAAAAGATTAC
ACACCGACTGAATATATTGAAGATTTAGAATATACTGAACAGAACATTTCAGGTCCAATAACTATGTTAAGTTCAGTTAT
AGAGTATGAGTACGGTTATGACGTTCCACCCGTTGATCTAATATATAGAGGGACCTTTAAAGGTAACTTTAGTATGAATA
TTGTTTTGGAACGTCCTGATGGTAATAAAATCAACTTGGTAAACAAAAGTTTTAGTTCGAACACTGAAAAAGACTTCAGA
ATATCAATTATTAATGAAGCAAATAACAATGTTCAAAGCTTTGCAAGGAGATATGTGCAAAATTTACCGCCAAGAGTTGA
TGTAAATACCGTGCTTTTTTCACAAGCCAACGATGAGCTTTTTTCAAATCCAACTCCATTAAATGGAACTTACAAGCTAA
ATATTAATCTAATAAAAATGACCGAGGACACTGCTATACAAGATACAAGGTTAGTTGTTTCTGGAAGTGTTTCTGGTTTA
CTAGGTACGGATAACTCTAAAAGAGATGTATGGAGTGGATTGGTAGCAGGCATTAAATGGGCTTTGTTCATAGGGCTTAT
GACATCTGCTATTTCGGTATCGGTAGGCGTGGTTTATGGAGTTGTTTCTGCGTATTATGGCGGTATAGTCGATTCTATAA
TGCAAAGAATCTGGGAAATTTTTATCAACATACCACTTCTTCCTGTTTTAATTGTTTTATCAGCAATATTTAAGCCCTCT
ATTTGGAGCCTTATTCTTATGATGAGTTTGTTTTTTTGGGTAGGCCCTGTTAAAACAGTAAGAAGTATGGCTTTGCAAAT
AAAAGAGGAAACCTATGTTGAAGCTGCAAAAGCTTTAGGTGCTTCGCATAGAAGAATAATTTTCAGACATATGGTTCCGA
TCTTGATTCCATACGCCTTTGCAAGTATGGCACTTAATGTTCCGAGCGCCATTCTTTACGAGGCAACCGTTAGTTTGCTT
GGTTTAGGAGATGCCACCATAGTCACCTGGGGGCAAATTCTCCACGATGCCATGAACGGAGGAGCCGTAACAAACGGTCT
TTGGTGGTGGGTTGTACCTCCTGGAATTGCTATTGCTTTAGTAGGTATGACTTTTGCCTTTTTAGGTTTTGCAATGGACA
CCATCTTAAATCCAAAATTGAGAACGAGGTAG

Upstream 100 bases:

>100_bases
GTAACCTTTCCATAACAACACTTATATACATTTCTGGTATCGTAGTTTTGGATTTGATATACGGCTTTTTAGACCCTAGA
ATAAAAGTTGGTGGGAAAGC

Downstream 100 bases:

>100_bases
ATATGAATGAATGAGATTTTAAATGTTAAAAATTTAAAAGTGTATTATTATACAAGAAAAGGTGTTGTAAAAGGATTGGA
CGATGTGAGTTTTTCCCTGA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNKTNRVAKQLKDFWDEFKQVKFGIAGIILLILFVILVVFEQFLIPFPEASTRWRDITYWEDNPRSVPPVWINWFSQKDY
TPTEYIEDLEYTEQNISGPITMLSSVIEYEYGYDVPPVDLIYRGTFKGNFSMNIVLERPDGNKINLVNKSFSSNTEKDFR
ISIINEANNNVQSFARRYVQNLPPRVDVNTVLFSQANDELFSNPTPLNGTYKLNINLIKMTEDTAIQDTRLVVSGSVSGL
LGTDNSKRDVWSGLVAGIKWALFIGLMTSAISVSVGVVYGVVSAYYGGIVDSIMQRIWEIFINIPLLPVLIVLSAIFKPS
IWSLILMMSLFFWVGPVKTVRSMALQIKEETYVEAAKALGASHRRIIFRHMVPILIPYAFASMALNVPSAILYEATVSLL
GLGDATIVTWGQILHDAMNGGAVTNGLWWWVVPPGIAIALVGMTFAFLGFAMDTILNPKLRTR

Sequences:

>Translated_463_residues
MNKTNRVAKQLKDFWDEFKQVKFGIAGIILLILFVILVVFEQFLIPFPEASTRWRDITYWEDNPRSVPPVWINWFSQKDY
TPTEYIEDLEYTEQNISGPITMLSSVIEYEYGYDVPPVDLIYRGTFKGNFSMNIVLERPDGNKINLVNKSFSSNTEKDFR
ISIINEANNNVQSFARRYVQNLPPRVDVNTVLFSQANDELFSNPTPLNGTYKLNINLIKMTEDTAIQDTRLVVSGSVSGL
LGTDNSKRDVWSGLVAGIKWALFIGLMTSAISVSVGVVYGVVSAYYGGIVDSIMQRIWEIFINIPLLPVLIVLSAIFKPS
IWSLILMMSLFFWVGPVKTVRSMALQIKEETYVEAAKALGASHRRIIFRHMVPILIPYAFASMALNVPSAILYEATVSLL
GLGDATIVTWGQILHDAMNGGAVTNGLWWWVVPPGIAIALVGMTFAFLGFAMDTILNPKLRTR
>Mature_463_residues
MNKTNRVAKQLKDFWDEFKQVKFGIAGIILLILFVILVVFEQFLIPFPEASTRWRDITYWEDNPRSVPPVWINWFSQKDY
TPTEYIEDLEYTEQNISGPITMLSSVIEYEYGYDVPPVDLIYRGTFKGNFSMNIVLERPDGNKINLVNKSFSSNTEKDFR
ISIINEANNNVQSFARRYVQNLPPRVDVNTVLFSQANDELFSNPTPLNGTYKLNINLIKMTEDTAIQDTRLVVSGSVSGL
LGTDNSKRDVWSGLVAGIKWALFIGLMTSAISVSVGVVYGVVSAYYGGIVDSIMQRIWEIFINIPLLPVLIVLSAIFKPS
IWSLILMMSLFFWVGPVKTVRSMALQIKEETYVEAAKALGASHRRIIFRHMVPILIPYAFASMALNVPSAILYEATVSLL
GLGDATIVTWGQILHDAMNGGAVTNGLWWWVVPPGIAIALVGMTFAFLGFAMDTILNPKLRTR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=239, Percent_Identity=31.3807531380753, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787498, Length=221, Percent_Identity=33.0316742081448, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788505, Length=163, Percent_Identity=34.9693251533742, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789964, Length=229, Percent_Identity=32.7510917030568, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787054, Length=227, Percent_Identity=25.9911894273128, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789889, Length=228, Percent_Identity=26.7543859649123, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 52066; Mature: 52066

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTNRVAKQLKDFWDEFKQVKFGIAGIILLILFVILVVFEQFLIPFPEASTRWRDITYW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
EDNPRSVPPVWINWFSQKDYTPTEYIEDLEYTEQNISGPITMLSSVIEYEYGYDVPPVDL
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHE
IYRGTFKGNFSMNIVLERPDGNKINLVNKSFSSNTEKDFRISIINEANNNVQSFARRYVQ
EEEEEECCCEEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
NLPPRVDVNTVLFSQANDELFSNPTPLNGTYKLNINLIKMTEDTAIQDTRLVVSGSVSGL
HCCCCCCCHHEEEECCCCHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCEEEEECCCCEE
LGTDNSKRDVWSGLVAGIKWALFIGLMTSAISVSVGVVYGVVSAYYGGIVDSIMQRIWEI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FINIPLLPVLIVLSAIFKPSIWSLILMMSLFFWVGPVKTVRSMALQIKEETYVEAAKALG
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHC
ASHRRIIFRHMVPILIPYAFASMALNVPSAILYEATVSLLGLGDATIVTWGQILHDAMNG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GAVTNGLWWWVVPPGIAIALVGMTFAFLGFAMDTILNPKLRTR
CEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNKTNRVAKQLKDFWDEFKQVKFGIAGIILLILFVILVVFEQFLIPFPEASTRWRDITYW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
EDNPRSVPPVWINWFSQKDYTPTEYIEDLEYTEQNISGPITMLSSVIEYEYGYDVPPVDL
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHE
IYRGTFKGNFSMNIVLERPDGNKINLVNKSFSSNTEKDFRISIINEANNNVQSFARRYVQ
EEEEEECCCEEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
NLPPRVDVNTVLFSQANDELFSNPTPLNGTYKLNINLIKMTEDTAIQDTRLVVSGSVSGL
HCCCCCCCHHEEEECCCCHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCEEEEECCCCEE
LGTDNSKRDVWSGLVAGIKWALFIGLMTSAISVSVGVVYGVVSAYYGGIVDSIMQRIWEI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FINIPLLPVLIVLSAIFKPSIWSLILMMSLFFWVGPVKTVRSMALQIKEETYVEAAKALG
HHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHC
ASHRRIIFRHMVPILIPYAFASMALNVPSAILYEATVSLLGLGDATIVTWGQILHDAMNG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
GAVTNGLWWWVVPPGIAIALVGMTFAFLGFAMDTILNPKLRTR
CEEECCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]