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The map label for this gene is fmt [H]

Identifier: 160901541

GI number: 160901541

Start: 45290

End: 46249

Strand: Direct

Name: fmt [H]

Synonym: Pmob_0050

Alternate gene names: 160901541

Gene position: 45290-46249 (Clockwise)

Preceding gene: 160901540

Following gene: 160901544

Centisome position: 2.09

GC content: 34.27

Gene sequence:

>960_bases
ATGACAAATAGTAAGGATTTTAAAATTGTTTTCATGGGGACACCTGATTTTGGTGCCCAAGTTTTGGAAGAACTAATAAA
AAACAATTTCAATGTTGTTGGAGTATTTTCCCAACCTGACAAACCTAAAGGGCGGGGGAAAAAGTTTCAACCACCAGCGG
TTAAGGAAGTTGCCCTAAAATACAATGTCCCGGTATTTCAACCAAAAAGCGTTAATAAGGGAGAGGGGTTTGACTTTTTG
AAAGAGCTGAACCCTGACATTATTATCACCGCAGCTTTTGGAAAAATATTAAAAACAAATGTTTTAAAACTTCCACCTAA
AGGATGTTGGAATGTACATGCTTCTTTATTGCCAAAATATAGAGGAGCAGCCCCAATTCAACGCGTTATAGAAAATGGAG
AAAAAGAAACGGGAATCAGTATTTTCAAGATGGTAGAAGCTCTTGATGCGGGAGATATAGCCATTCAAAAAAGTGTCCCC
ATTGAAATAAACGACAATTACGGCATAGTTTATGAAAAATTATTATCACTTGCAAAAGAAACTGTTTTAGAGTTTTTGAA
CTCATTCGATCATTTAACTTTGAAACCACAAAACGAAGAAGAAGCCTCATATGCAGAAAAAATTACAAAAGAAGATCTAA
TTGTAGATTTTAATAATGATGCTATAAAGGTTCATAACAAGATTAGAGCTTACGATCCATACCCCGGGGTAAGAAGCGTC
TACGAAAAAGAAGAGGTAAAGATATTTGGTTCGGAATTTTCTGATGATTTGTTTACAATAGAAAATAAAGAAGAACCAGG
AACAATAATACGTATTGAAAAAGACGGAATACTTGTAAAATGTAGAGATGGGGCTGTAAAGATAAAAGAGATACAATTCC
CTGGTAAAAAAAGAATATCTACAATAGATGCCATCAATGGGAAAAAACTAAAATTATTGGGACATTTCAGCCCTTATTAA

Upstream 100 bases:

>100_bases
AATTACCCATTGTAAAGAAAGCCAGGTTAAAAAAGGAATTGAACCAACTAATAGAAAAGGGCAAAAAACGTGCATGGGAG
TTAGGTGAAACGGTAAAAAC

Downstream 100 bases:

>100_bases
AGAAAAACTTTTCAGCATTGCTTTTTGTGATCTCTTTCAAAGTTTCAACATCTATCCCTTTTATTTCTGATATTTTTTCA
TAAACATATTTTACATAAGT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTNSKDFKIVFMGTPDFGAQVLEELIKNNFNVVGVFSQPDKPKGRGKKFQPPAVKEVALKYNVPVFQPKSVNKGEGFDFL
KELNPDIIITAAFGKILKTNVLKLPPKGCWNVHASLLPKYRGAAPIQRVIENGEKETGISIFKMVEALDAGDIAIQKSVP
IEINDNYGIVYEKLLSLAKETVLEFLNSFDHLTLKPQNEEEASYAEKITKEDLIVDFNNDAIKVHNKIRAYDPYPGVRSV
YEKEEVKIFGSEFSDDLFTIENKEEPGTIIRIEKDGILVKCRDGAVKIKEIQFPGKKRISTIDAINGKKLKLLGHFSPY

Sequences:

>Translated_319_residues
MTNSKDFKIVFMGTPDFGAQVLEELIKNNFNVVGVFSQPDKPKGRGKKFQPPAVKEVALKYNVPVFQPKSVNKGEGFDFL
KELNPDIIITAAFGKILKTNVLKLPPKGCWNVHASLLPKYRGAAPIQRVIENGEKETGISIFKMVEALDAGDIAIQKSVP
IEINDNYGIVYEKLLSLAKETVLEFLNSFDHLTLKPQNEEEASYAEKITKEDLIVDFNNDAIKVHNKIRAYDPYPGVRSV
YEKEEVKIFGSEFSDDLFTIENKEEPGTIIRIEKDGILVKCRDGAVKIKEIQFPGKKRISTIDAINGKKLKLLGHFSPY
>Mature_318_residues
TNSKDFKIVFMGTPDFGAQVLEELIKNNFNVVGVFSQPDKPKGRGKKFQPPAVKEVALKYNVPVFQPKSVNKGEGFDFLK
ELNPDIIITAAFGKILKTNVLKLPPKGCWNVHASLLPKYRGAAPIQRVIENGEKETGISIFKMVEALDAGDIAIQKSVPI
EINDNYGIVYEKLLSLAKETVLEFLNSFDHLTLKPQNEEEASYAEKITKEDLIVDFNNDAIKVHNKIRAYDPYPGVRSVY
EKEEVKIFGSEFSDDLFTIENKEEPGTIIRIEKDGILVKCRDGAVKIKEIQFPGKKRISTIDAINGKKLKLLGHFSPY

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=305, Percent_Identity=25.9016393442623, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI21614513, Length=325, Percent_Identity=27.0769230769231, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI164663775, Length=323, Percent_Identity=24.7678018575851, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1789683, Length=308, Percent_Identity=39.9350649350649, Blast_Score=240, Evalue=8e-65,
Organism=Escherichia coli, GI1788589, Length=313, Percent_Identity=29.073482428115, Blast_Score=153, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI133930964, Length=319, Percent_Identity=29.7805642633229, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319458, Length=358, Percent_Identity=25.4189944134078, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550868, Length=308, Percent_Identity=29.2207792207792, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571984, Length=228, Percent_Identity=29.8245614035088, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24585660, Length=321, Percent_Identity=25.2336448598131, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 35818; Mature: 35687

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSKDFKIVFMGTPDFGAQVLEELIKNNFNVVGVFSQPDKPKGRGKKFQPPAVKEVALK
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHEEE
YNVPVFQPKSVNKGEGFDFLKELNPDIIITAAFGKILKTNVLKLPPKGCWNVHASLLPKY
ECCCEECCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHHCCEEECCCCCCHHHHHHHCCCC
RGAAPIQRVIENGEKETGISIFKMVEALDAGDIAIQKSVPIEINDNYGIVYEKLLSLAKE
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHH
TVLEFLNSFDHLTLKPQNEEEASYAEKITKEDLIVDFNNDAIKVHNKIRAYDPYPGVRSV
HHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCEEEEECCCEEEEECEEEECCCCCCHHHH
YEKEEVKIFGSEFSDDLFTIENKEEPGTIIRIEKDGILVKCRDGAVKIKEIQFPGKKRIS
HCCCCEEEECCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCCCEEEEEEECCCCCCCE
TIDAINGKKLKLLGHFSPY
EEECCCCCEEEEEECCCCC
>Mature Secondary Structure 
TNSKDFKIVFMGTPDFGAQVLEELIKNNFNVVGVFSQPDKPKGRGKKFQPPAVKEVALK
CCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHEEE
YNVPVFQPKSVNKGEGFDFLKELNPDIIITAAFGKILKTNVLKLPPKGCWNVHASLLPKY
ECCCEECCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHHCCEEECCCCCCHHHHHHHCCCC
RGAAPIQRVIENGEKETGISIFKMVEALDAGDIAIQKSVPIEINDNYGIVYEKLLSLAKE
CCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHH
TVLEFLNSFDHLTLKPQNEEEASYAEKITKEDLIVDFNNDAIKVHNKIRAYDPYPGVRSV
HHHHHHHCCCCEEECCCCCHHHHHHHHHCCCCEEEEECCCEEEEECEEEECCCCCCHHHH
YEKEEVKIFGSEFSDDLFTIENKEEPGTIIRIEKDGILVKCRDGAVKIKEIQFPGKKRIS
HCCCCEEEECCCCCCCEEEEECCCCCCCEEEEECCCEEEEECCCCEEEEEEECCCCCCCE
TIDAINGKKLKLLGHFSPY
EEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA