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The map label for this gene is sigW [H]

Identifier: 160876847

GI number: 160876847

Start: 4411027

End: 4411560

Strand: Direct

Name: sigW [H]

Synonym: Sbal195_3743

Alternate gene names: 160876847

Gene position: 4411027-4411560 (Clockwise)

Preceding gene: 160876845

Following gene: 160876848

Centisome position: 82.49

GC content: 44.76

Gene sequence:

>534_bases
GTGACGGCAGGGATACTCCCACTCAATAGCGCAATGTCTGATTTTGAGCTGGCCACCTTAGCCAGCCAAGGCAACAGAGC
CGCATTTAAACTGCTGTATCAAAGCCATCACCAACGTATTTATGCCTTATCACTGCGCCTTTGTGGTCATAAAACTATGG
CGGAAGACATTACCCAAGAGTGTTTTATTTTAGTGTGGCAGAAGTTGCCACAATTTCGAGGTGAGAGTCAGTTTTCGACT
TGGTTACACAGCATTTGTGTCAATCAAGCCTTGAGCTGTATTCGTAAACAACAATCATTTTGGGCACGATTTATCCCGCT
GGAAAATGAAACTGAACCTATGAGTTCAGATGAAAGTTATAGCGGATTAGACAAGTTGATTTTCAAACTGCCGCAGCGGG
CTCGCATAGTGTTCGTACTTTGCGCCATCGAAGGTTATCAACATGATGAAATCGCTGACTTACTTGGCATTGCGGTCGGC
ACTAGCAAGACCCAATACCATAGAGCTAAGCAACTACTACAGGAGATGCTGTAA

Upstream 100 bases:

>100_bases
TAATGAATCTTAATAAAATATATTTTTTACAGTTCCAAACCTTTTGCAGCATTCAGTGCGTCAAAACTACAACACTTAAT
AATTATGGCAGGGAATGACA

Downstream 100 bases:

>100_bases
TGACGTTAACGCCGCTTTCCCGTGAACAACAGCTTGAGCAACTGATCAATAGCGCCCCCAAAGAAATGTCGCCCAGCCAT
GATCTGTGGCAAGGCATTGA

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MTAGILPLNSAMSDFELATLASQGNRAAFKLLYQSHHQRIYALSLRLCGHKTMAEDITQECFILVWQKLPQFRGESQFST
WLHSICVNQALSCIRKQQSFWARFIPLENETEPMSSDESYSGLDKLIFKLPQRARIVFVLCAIEGYQHDEIADLLGIAVG
TSKTQYHRAKQLLQEML

Sequences:

>Translated_177_residues
MTAGILPLNSAMSDFELATLASQGNRAAFKLLYQSHHQRIYALSLRLCGHKTMAEDITQECFILVWQKLPQFRGESQFST
WLHSICVNQALSCIRKQQSFWARFIPLENETEPMSSDESYSGLDKLIFKLPQRARIVFVLCAIEGYQHDEIADLLGIAVG
TSKTQYHRAKQLLQEML
>Mature_176_residues
TAGILPLNSAMSDFELATLASQGNRAAFKLLYQSHHQRIYALSLRLCGHKTMAEDITQECFILVWQKLPQFRGESQFSTW
LHSICVNQALSCIRKQQSFWARFIPLENETEPMSSDESYSGLDKLIFKLPQRARIVFVLCAIEGYQHDEIADLLGIAVGT
SKTQYHRAKQLLQEML

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20212; Mature: 20080

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGILPLNSAMSDFELATLASQGNRAAFKLLYQSHHQRIYALSLRLCGHKTMAEDITQE
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
CFILVWQKLPQFRGESQFSTWLHSICVNQALSCIRKQQSFWARFIPLENETEPMSSDESY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
SGLDKLIFKLPQRARIVFVLCAIEGYQHDEIADLLGIAVGTSKTQYHRAKQLLQEML
HHHHHHHHHCCCHHHHEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TAGILPLNSAMSDFELATLASQGNRAAFKLLYQSHHQRIYALSLRLCGHKTMAEDITQE
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
CFILVWQKLPQFRGESQFSTWLHSICVNQALSCIRKQQSFWARFIPLENETEPMSSDESY
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
SGLDKLIFKLPQRARIVFVLCAIEGYQHDEIADLLGIAVGTSKTQYHRAKQLLQEML
HHHHHHHHHCCCHHHHEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]