Click here to switch to the map view.

The map label for this gene is nhaC [H]

Identifier: 160876687

GI number: 160876687

Start: 4212028

End: 4213362

Strand: Direct

Name: nhaC [H]

Synonym: Sbal195_3581

Alternate gene names: 160876687

Gene position: 4212028-4213362 (Clockwise)

Preceding gene: 160876685

Following gene: 160876688

Centisome position: 78.77

GC content: 48.24

Gene sequence:

>1335_bases
TTGAGCAATCCAACACCAGCAACACAGCACAGCCCGACATCTTTCATTGCCCTGTTGCCATTATTTGTTTTCCTTGGTCT
TTTCATTGGCGCGGGTGTGTATTTCCAAAGCCAAGGTGTCGACTTCGCCTTCTATCAATTACCGAGTGTTATCGCCATTT
TACCTGCGATTATTCTGGCGTTGATTCTATCAAAGCAGAAATTGAATCAATCGATTGATACCTTTATTGGCGGTATTGGT
CACAGCAACATTATTGCGATGTGTTTGATTTATCTATTAGCAGGCGCTTTCGCGGCGGTCGCTAAAGCCACTGGCGGCGT
CGATGCCACCGTTGCTCTGGGTTTATCACTGATCCCATCAAACTTGTTGTTACCCGGTTTCTTCGTGATTGCGGCCTTTA
TCGCAACAGCCATGGGGACATCAATGGGCACCATAGCTGCTGTCGCACCCATCGCCCTCGGCGTGGCCGACCAAGCACAA
ATCGACTACGCCCTGATGGCAGGTGCGGTCATGTCTGGCGCCCTATTCGGTGACAACTTATCGATTATTTCAGATACCAC
GATTGCAGCCACCCGTACTCAGGGCTGTGATATGAAAGATAAATTCCGTGAAAACCTGATTTTCGCTATCCCAGCATCAC
TGCTTACCTTGATTGCCTTTGTATTTGCAGGCCAAGGCCAAGCGGAATTAGCCACGCAGAACATAGATCTCATTAAGGTC
ATTCCTTATCTGACCATTTTGATCTTAGCGGTGGCGGGTCTGAACGTATTTGTGGTCTTAACCTTAGGTATCTTATTAGC
GGGCGCTACGGGTCTGTTTACCATGGATTACGGCGTGATCCAATTTGGTAAAGATATTTATGCTGGCTTTAGCAATATGC
AGGAGATTTTCATTCTGTCTATGCTGGTCGGTGGTTTAGCGGCACTTATGCAGCAACAAGGTGGTCTTGCCTTTGTGAGC
AAACAGATTGAAAAGCTGATCACGCGTTTTTCAAAGGCACAAGGTGAAGCCTCATGCCGCGCCGCAGAACTGGGTATGGC
TGGCATAGTCGCAGTGACTAACACTTGTGTGGCCAACAACACTGTTTCTATCGTGGTGACCGGTGATATTGCTAAAGACT
TAGCCGAGAAACATGGTGTGAGCCCAAAACGTGCCGCCAGCGTCCTCGATATTTTCGCCTGTATTATCCAAGGTTTGATC
CCGTATGGCGCACAAGCCTTGCTGATCGCCTCGACCTTTAGCATCACCCCATTGGCTGCGGTATCACACGCTTGGTACTG
TATGATTTTAGCCGTCGTGGCCGTTGCGATTGTGATTTTCCGTAAACGTCATTAA

Upstream 100 bases:

>100_bases
TCAAGTTGCTAAGATACGATGCCGAAGCGACACTAAATTTAAGCGAGTTTGACTGCTAAGGAACCAGCGGAAAGAACTCT
AAGCGAAAGAGAGATAACAT

Downstream 100 bases:

>100_bases
TAAGTCGCACTGTACTTATCGCTTGTTAAACAGCAGGTTGAAATAGCTAATTAAGATGCTGATAAGTACAATTGAAGGAG
CCGAATTCGGCTCCTTTTTT

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSNPTPATQHSPTSFIALLPLFVFLGLFIGAGVYFQSQGVDFAFYQLPSVIAILPAIILALILSKQKLNQSIDTFIGGIG
HSNIIAMCLIYLLAGAFAAVAKATGGVDATVALGLSLIPSNLLLPGFFVIAAFIATAMGTSMGTIAAVAPIALGVADQAQ
IDYALMAGAVMSGALFGDNLSIISDTTIAATRTQGCDMKDKFRENLIFAIPASLLTLIAFVFAGQGQAELATQNIDLIKV
IPYLTILILAVAGLNVFVVLTLGILLAGATGLFTMDYGVIQFGKDIYAGFSNMQEIFILSMLVGGLAALMQQQGGLAFVS
KQIEKLITRFSKAQGEASCRAAELGMAGIVAVTNTCVANNTVSIVVTGDIAKDLAEKHGVSPKRAASVLDIFACIIQGLI
PYGAQALLIASTFSITPLAAVSHAWYCMILAVVAVAIVIFRKRH

Sequences:

>Translated_444_residues
MSNPTPATQHSPTSFIALLPLFVFLGLFIGAGVYFQSQGVDFAFYQLPSVIAILPAIILALILSKQKLNQSIDTFIGGIG
HSNIIAMCLIYLLAGAFAAVAKATGGVDATVALGLSLIPSNLLLPGFFVIAAFIATAMGTSMGTIAAVAPIALGVADQAQ
IDYALMAGAVMSGALFGDNLSIISDTTIAATRTQGCDMKDKFRENLIFAIPASLLTLIAFVFAGQGQAELATQNIDLIKV
IPYLTILILAVAGLNVFVVLTLGILLAGATGLFTMDYGVIQFGKDIYAGFSNMQEIFILSMLVGGLAALMQQQGGLAFVS
KQIEKLITRFSKAQGEASCRAAELGMAGIVAVTNTCVANNTVSIVVTGDIAKDLAEKHGVSPKRAASVLDIFACIIQGLI
PYGAQALLIASTFSITPLAAVSHAWYCMILAVVAVAIVIFRKRH
>Mature_443_residues
SNPTPATQHSPTSFIALLPLFVFLGLFIGAGVYFQSQGVDFAFYQLPSVIAILPAIILALILSKQKLNQSIDTFIGGIGH
SNIIAMCLIYLLAGAFAAVAKATGGVDATVALGLSLIPSNLLLPGFFVIAAFIATAMGTSMGTIAAVAPIALGVADQAQI
DYALMAGAVMSGALFGDNLSIISDTTIAATRTQGCDMKDKFRENLIFAIPASLLTLIAFVFAGQGQAELATQNIDLIKVI
PYLTILILAVAGLNVFVVLTLGILLAGATGLFTMDYGVIQFGKDIYAGFSNMQEIFILSMLVGGLAALMQQQGGLAFVSK
QIEKLITRFSKAQGEASCRAAELGMAGIVAVTNTCVANNTVSIVVTGDIAKDLAEKHGVSPKRAASVLDIFACIIQGLIP
YGAQALLIASTFSITPLAAVSHAWYCMILAVVAVAIVIFRKRH

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 46288; Mature: 46157

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPTPATQHSPTSFIALLPLFVFLGLFIGAGVYFQSQGVDFAFYQLPSVIAILPAIILA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LILSKQKLNQSIDTFIGGIGHSNIIAMCLIYLLAGAFAAVAKATGGVDATVALGLSLIPS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NLLLPGFFVIAAFIATAMGTSMGTIAAVAPIALGVADQAQIDYALMAGAVMSGALFGDNL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
SIISDTTIAATRTQGCDMKDKFRENLIFAIPASLLTLIAFVFAGQGQAELATQNIDLIKV
EEEECCEEEEECCCCCCHHHHHHHCEEHCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHH
IPYLTILILAVAGLNVFVVLTLGILLAGATGLFTMDYGVIQFGKDIYAGFSNMQEIFILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MLVGGLAALMQQQGGLAFVSKQIEKLITRFSKAQGEASCRAAELGMAGIVAVTNTCVANN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHEECC
TVSIVVTGDIAKDLAEKHGVSPKRAASVLDIFACIIQGLIPYGAQALLIASTFSITPLAA
EEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEHHCCCCHHHH
VSHAWYCMILAVVAVAIVIFRKRH
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNPTPATQHSPTSFIALLPLFVFLGLFIGAGVYFQSQGVDFAFYQLPSVIAILPAIILA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LILSKQKLNQSIDTFIGGIGHSNIIAMCLIYLLAGAFAAVAKATGGVDATVALGLSLIPS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
NLLLPGFFVIAAFIATAMGTSMGTIAAVAPIALGVADQAQIDYALMAGAVMSGALFGDNL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
SIISDTTIAATRTQGCDMKDKFRENLIFAIPASLLTLIAFVFAGQGQAELATQNIDLIKV
EEEECCEEEEECCCCCCHHHHHHHCEEHCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHH
IPYLTILILAVAGLNVFVVLTLGILLAGATGLFTMDYGVIQFGKDIYAGFSNMQEIFILS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
MLVGGLAALMQQQGGLAFVSKQIEKLITRFSKAQGEASCRAAELGMAGIVAVTNTCVANN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHEECC
TVSIVVTGDIAKDLAEKHGVSPKRAASVLDIFACIIQGLIPYGAQALLIASTFSITPLAA
EEEEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHEEHHCCCCHHHH
VSHAWYCMILAVVAVAIVIFRKRH
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]