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The map label for this gene is hlyB [H]

Identifier: 160876685

GI number: 160876685

Start: 4208450

End: 4210081

Strand: Direct

Name: hlyB [H]

Synonym: Sbal195_3579

Alternate gene names: 160876685

Gene position: 4208450-4210081 (Clockwise)

Preceding gene: 160876684

Following gene: 160876687

Centisome position: 78.7

GC content: 47.06

Gene sequence:

>1632_bases
ATGTTTAACAGTATTCGCGTTAAGTTTTCGTTGATGTTTGCCATTATGGCGACAGCGCTCATTGTTATGGCCGTCACCGA
CGCCATGCAAAGCCGTGCAACGGTAAAGCAGATGCAAGAGTTCAGTCAGTTATTTAATCCTGCGATTTCGGCAATTCTCA
ATGCAGACCGCGATCTTTACCAAGCACAGCTCAGTGAAGAAGTGTTGTTGAGGGAAGAATTATCAGCCGAGAATCGCAAG
AGTGAAATTGATAACTGGCAAGAAAACGTCGACCAAGCCCGTGACCGAATGGGCGAGTTTAAAAAAATCCTTAAAGACCA
TCTGCTCGTACTGCAATCCACCAATGGCTTTGAAGCGCAATTTTCCCTTTGGTATCAAGCATCATCTGAAGTCATTAATG
CCGTCAAAAGTAATGACTTTGAACGCGCGAAACAACTCCACGAAACCAAATCCAAACAAGAATTTAAAGCCTTAAGAAGC
ATCTATAATGCCGCAGGGGAAGCGGCCGATAACCGCGTCAAAGAGCTGGACTTGCAAGCGACAGAACAGGCAACCACCCA
AACCCAAATATCCCTCACCATAGCCAGCTTAGTGGCCATAGTCGCTCTGTTGATTGCCTACTTCGGCCCTAAAATCATCG
TTAATGCCATTAAAGATATCACTAGCAGGATCAATGACATTGTTGATGGTGACGGTAACTTAACTCAACGGATCCCTATC
AAACGTCAGGATGAAATCGGTGAGCTTGCCGAGGCCTTTAACTTGTTTGTAGAACAACTGCAGCAAATGGTGATCTCGAT
TATTGGCCAAACCAAGGATGTGAGCCAAACCGTTGAAAGCCTTGCGACTAAGTCGGCAACCACTATCAACATCAGTCATG
AACAAGAGCAGTTTGTCGATACCATAGTCACAGCAGTCAATGAAATGAGTGCCGCCGTAAGGGAAGTCGCCAGCAATGCC
CTGCACACGGCAACCGAAATCACTAAGGTGAACGACCAAACGGTGGAAGGTAAAAATATCCTTGCCCAGTCCGTTAATCA
TATTCAGCAACTGTCTGAGTCGGTTAAAAATGCCGTAACGGTTATCGAAAAACTCTCAGTCAATTCTGCCAATATTGCCT
CAGTGCTCGATGTGATCCGCTCTATTGCTGAGCAAACTAACCTGCTCGCCCTTAACGCGGCCATTGAAGCGGCGCGTGCT
GGCGAACAGGGCCGCGGCTTTGCCGTGGTCGCCGACGAAGTGCGTACACTAGCGAGTCGCACCGAAACCTCGACCCAAGA
TATTCAGCGTATGATTGAAGAGTTACAACGCGGCGTAAATGATGCAGTTAAAAGCATTGAATCGGGCGCCAGCCTGACCA
CATCAACCGTCACCCTCGCCAGCCAAACCCAAGATGCATTGGATGAAATCCTAAACTCCACCTCTAAGGTCAGCGAGATG
TCCACTCAAACGGCAACGGCGACCGAAGAGCAAACCCATGTAACCGAAGAAATTAACCGTAACTTGACTGAATTATCCGA
TAAAACCAGATACTGCAACTTAGTCATTCAAGAGACTCAGCAAATCGTCGTCAACACTAAGGCCATTTGCAGTAACCTAC
AAAAAGAAGTGGCGCGATTTAAAGTCGCCTAA

Upstream 100 bases:

>100_bases
CAAAACTTCGCACCGAATCCCATCGCAATTTACTGCATGTAAAAGCAATTTCATAAATAACGGCTAAGCTATTTATTAAG
TTATTAATGGAGATGTTCCT

Downstream 100 bases:

>100_bases
ACTGGCGGGCTGCTAACGATACATGGTTAGCGATAAACGGTTAGTGACAAGCAGTTAATAACAGACCGCTTGCGACAAAC
AGCTAAATCGAAAAGAGTGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MFNSIRVKFSLMFAIMATALIVMAVTDAMQSRATVKQMQEFSQLFNPAISAILNADRDLYQAQLSEEVLLREELSAENRK
SEIDNWQENVDQARDRMGEFKKILKDHLLVLQSTNGFEAQFSLWYQASSEVINAVKSNDFERAKQLHETKSKQEFKALRS
IYNAAGEAADNRVKELDLQATEQATTQTQISLTIASLVAIVALLIAYFGPKIIVNAIKDITSRINDIVDGDGNLTQRIPI
KRQDEIGELAEAFNLFVEQLQQMVISIIGQTKDVSQTVESLATKSATTINISHEQEQFVDTIVTAVNEMSAAVREVASNA
LHTATEITKVNDQTVEGKNILAQSVNHIQQLSESVKNAVTVIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTETSTQDIQRMIEELQRGVNDAVKSIESGASLTTSTVTLASQTQDALDEILNSTSKVSEM
STQTATATEEQTHVTEEINRNLTELSDKTRYCNLVIQETQQIVVNTKAICSNLQKEVARFKVA

Sequences:

>Translated_543_residues
MFNSIRVKFSLMFAIMATALIVMAVTDAMQSRATVKQMQEFSQLFNPAISAILNADRDLYQAQLSEEVLLREELSAENRK
SEIDNWQENVDQARDRMGEFKKILKDHLLVLQSTNGFEAQFSLWYQASSEVINAVKSNDFERAKQLHETKSKQEFKALRS
IYNAAGEAADNRVKELDLQATEQATTQTQISLTIASLVAIVALLIAYFGPKIIVNAIKDITSRINDIVDGDGNLTQRIPI
KRQDEIGELAEAFNLFVEQLQQMVISIIGQTKDVSQTVESLATKSATTINISHEQEQFVDTIVTAVNEMSAAVREVASNA
LHTATEITKVNDQTVEGKNILAQSVNHIQQLSESVKNAVTVIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTETSTQDIQRMIEELQRGVNDAVKSIESGASLTTSTVTLASQTQDALDEILNSTSKVSEM
STQTATATEEQTHVTEEINRNLTELSDKTRYCNLVIQETQQIVVNTKAICSNLQKEVARFKVA
>Mature_543_residues
MFNSIRVKFSLMFAIMATALIVMAVTDAMQSRATVKQMQEFSQLFNPAISAILNADRDLYQAQLSEEVLLREELSAENRK
SEIDNWQENVDQARDRMGEFKKILKDHLLVLQSTNGFEAQFSLWYQASSEVINAVKSNDFERAKQLHETKSKQEFKALRS
IYNAAGEAADNRVKELDLQATEQATTQTQISLTIASLVAIVALLIAYFGPKIIVNAIKDITSRINDIVDGDGNLTQRIPI
KRQDEIGELAEAFNLFVEQLQQMVISIIGQTKDVSQTVESLATKSATTINISHEQEQFVDTIVTAVNEMSAAVREVASNA
LHTATEITKVNDQTVEGKNILAQSVNHIQQLSESVKNAVTVIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARA
GEQGRGFAVVADEVRTLASRTETSTQDIQRMIEELQRGVNDAVKSIESGASLTTSTVTLASQTQDALDEILNSTSKVSEM
STQTATATEEQTHVTEEINRNLTELSDKTRYCNLVIQETQQIVVNTKAICSNLQKEVARFKVA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=424, Percent_Identity=26.1792452830189, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787690, Length=347, Percent_Identity=27.6657060518732, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788195, Length=343, Percent_Identity=27.4052478134111, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=359, Percent_Identity=27.5766016713092, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789453, Length=348, Percent_Identity=28.448275862069, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59890; Mature: 59890

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSIRVKFSLMFAIMATALIVMAVTDAMQSRATVKQMQEFSQLFNPAISAILNADRDLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QAQLSEEVLLREELSAENRKSEIDNWQENVDQARDRMGEFKKILKDHLLVLQSTNGFEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
FSLWYQASSEVINAVKSNDFERAKQLHETKSKQEFKALRSIYNAAGEAADNRVKELDLQA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEQATTQTQISLTIASLVAIVALLIAYFGPKIIVNAIKDITSRINDIVDGDGNLTQRIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KRQDEIGELAEAFNLFVEQLQQMVISIIGQTKDVSQTVESLATKSATTINISHEQEQFVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHH
TIVTAVNEMSAAVREVASNALHTATEITKVNDQTVEGKNILAQSVNHIQQLSESVKNAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASR
HHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TETSTQDIQRMIEELQRGVNDAVKSIESGASLTTSTVTLASQTQDALDEILNSTSKVSEM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
STQTATATEEQTHVTEEINRNLTELSDKTRYCNLVIQETQQIVVNTKAICSNLQKEVARF
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVA
CCC
>Mature Secondary Structure
MFNSIRVKFSLMFAIMATALIVMAVTDAMQSRATVKQMQEFSQLFNPAISAILNADRDLY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QAQLSEEVLLREELSAENRKSEIDNWQENVDQARDRMGEFKKILKDHLLVLQSTNGFEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
FSLWYQASSEVINAVKSNDFERAKQLHETKSKQEFKALRSIYNAAGEAADNRVKELDLQA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEQATTQTQISLTIASLVAIVALLIAYFGPKIIVNAIKDITSRINDIVDGDGNLTQRIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KRQDEIGELAEAFNLFVEQLQQMVISIIGQTKDVSQTVESLATKSATTINISHEQEQFVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHH
TIVTAVNEMSAAVREVASNALHTATEITKVNDQTVEGKNILAQSVNHIQQLSESVKNAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIEKLSVNSANIASVLDVIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASR
HHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
TETSTQDIQRMIEELQRGVNDAVKSIESGASLTTSTVTLASQTQDALDEILNSTSKVSEM
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
STQTATATEEQTHVTEEINRNLTELSDKTRYCNLVIQETQQIVVNTKAICSNLQKEVARF
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]