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The map label for this gene is can [H]

Identifier: 160875587

GI number: 160875587

Start: 2927471

End: 2928088

Strand: Direct

Name: can [H]

Synonym: Sbal195_2475

Alternate gene names: 160875587

Gene position: 2927471-2928088 (Clockwise)

Preceding gene: 160875586

Following gene: 160875588

Centisome position: 54.75

GC content: 47.57

Gene sequence:

>618_bases
ATGAAACTACTCAAACCTTTATTCGACAACAACCGCCGCTGGGCCGGACGTATACGTCAAGAAAATCCTGATTTTTTTGA
GCAATTAGCGAAACAGCAACATCCTGAATATCTGTGGATTGGCTGCTCGGATAGTCGCGTACCGTCTAACCAAATCATCG
ATCTTATGCCCGGTGAAGTCTTTGTTCACCGCAATATTGCCAACATGGTGATCCATACCGATCTTAACTGCTTATCTGTG
CTGCAATACGCCGTTGATGTGCTCAAGGTGAAGCACATTATGGTGGTGGGTCACTACGGCTGTGGTGGTGTCCGTGCGGC
CATGAGTCAGCAACGCTTAGGCCTTATCGATAACTGGCTCGGGCATTTACGTGATATCTACCGTATCTATCAAGATGAAT
TAAAACAGATGGATGAAGCCAAACGTTTTGATCGCCTGTGCGAGCTCAACGTGATTGAGCAGGTTGCCAACGTCACCAGT
TCAACCATAGTGCAAGAAGCCTGGGATCGCGGCCAAGAAGTAGCAGTACACGGCTGGATTTACGGCATTGATAACGGTTT
ACTGACAGATTTAGATGTCACTGTCGATCGTGAACACGGCTTAGCCAATCCACGCTAA

Upstream 100 bases:

>100_bases
CAGAAACAATTTTGCTGGTATACTCTTGCTAAAAATGTGCTGCTTGCATGAATTAGAGCATGAGAAGACATTTTATATGT
CAATAAAACAATAGGTTAAA

Downstream 100 bases:

>100_bases
CGGCCTGAATATGTGCTTTTAACCCTCAGCTGAGTGTCAGCTATGCTCAGATAAAACCTGCCCCTGTGCAGGTTTTTCTT
TTTCCATGGCAATTTTCAGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKLLKPLFDNNRRWAGRIRQENPDFFEQLAKQQHPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAVDVLKVKHIMVVGHYGCGGVRAAMSQQRLGLIDNWLGHLRDIYRIYQDELKQMDEAKRFDRLCELNVIEQVANVTS
STIVQEAWDRGQEVAVHGWIYGIDNGLLTDLDVTVDREHGLANPR

Sequences:

>Translated_205_residues
MKLLKPLFDNNRRWAGRIRQENPDFFEQLAKQQHPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAVDVLKVKHIMVVGHYGCGGVRAAMSQQRLGLIDNWLGHLRDIYRIYQDELKQMDEAKRFDRLCELNVIEQVANVTS
STIVQEAWDRGQEVAVHGWIYGIDNGLLTDLDVTVDREHGLANPR
>Mature_205_residues
MKLLKPLFDNNRRWAGRIRQENPDFFEQLAKQQHPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAVDVLKVKHIMVVGHYGCGGVRAAMSQQRLGLIDNWLGHLRDIYRIYQDELKQMDEAKRFDRLCELNVIEQVANVTS
STIVQEAWDRGQEVAVHGWIYGIDNGLLTDLDVTVDREHGLANPR

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=211, Percent_Identity=57.8199052132701, Blast_Score=256, Evalue=6e-70,
Organism=Escherichia coli, GI1786534, Length=188, Percent_Identity=33.5106382978723, Blast_Score=99, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324292, Length=196, Percent_Identity=33.1632653061224, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23620; Mature: 23620

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKPLFDNNRRWAGRIRQENPDFFEQLAKQQHPEYLWIGCSDSRVPSNQIIDLMPGEV
CCCHHHHHCCCCHHECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCE
FVHRNIANMVIHTDLNCLSVLQYAVDVLKVKHIMVVGHYGCGGVRAAMSQQRLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCHHHHHH
GHLRDIYRIYQDELKQMDEAKRFDRLCELNVIEQVANVTSSTIVQEAWDRGQEVAVHGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
YGIDNGLLTDLDVTVDREHGLANPR
EECCCCCEECEEEEEECCCCCCCCC
>Mature Secondary Structure
MKLLKPLFDNNRRWAGRIRQENPDFFEQLAKQQHPEYLWIGCSDSRVPSNQIIDLMPGEV
CCCHHHHHCCCCHHECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCE
FVHRNIANMVIHTDLNCLSVLQYAVDVLKVKHIMVVGHYGCGGVRAAMSQQRLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCHHHHHH
GHLRDIYRIYQDELKQMDEAKRFDRLCELNVIEQVANVTSSTIVQEAWDRGQEVAVHGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
YGIDNGLLTDLDVTVDREHGLANPR
EECCCCCEECEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]