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The map label for this gene is hutH [H]

Identifier: 160873466

GI number: 160873466

Start: 388030

End: 389604

Strand: Reverse

Name: hutH [H]

Synonym: Sbal195_0341

Alternate gene names: 160873466

Gene position: 389604-388030 (Counterclockwise)

Preceding gene: 160873467

Following gene: 160873465

Centisome position: 7.29

GC content: 52.38

Gene sequence:

>1575_bases
ATGAGCCACACCAAAGCAGCCGACTCCGAGAGTCAATCAGACCTACAGACTGTTGAGTTCGGCCGTCAGTTTCTCACCTT
AGAACAAGTGGTTGCCGTCGCCAAGGGCGCGCCAGTCAAGCTCTGTGACGATGCGGATTATCAAGAATATATCCAAAAAG
GTGCGCGCTTTATCGATAGCCTGCTGCACGAAGAAGGCGTGGTCTATGGCGTAACCACAGGTTATGGCGACTCTTGCACT
GTCAATGTGAGCTTAGATCTGGTCCACGAATTGCCACTGCATTTAACCCGCTTCCACGGCTGCGGTTTAGGCGAGACCTT
AAGCATAATGCAGGCCCGCGCTGTGATGGCTTGCCGTTTAAACTCCTTAGCCATTGGCAAATCTGGCGTGACCTATGAGC
TATTAAAGCGTATCGAAACCTTGCTCAATCTCAACATAGTGCCAGTGATCCCAGAGGAAGGTTCGGTCGGCGCCAGCGGG
GATTTAACGCCGTTGTCGTATTTAGCCGCCGTGTTAGTCGGTGAGCGCGAAGTGATTTACCAAGGTGAGCGCCAAGCGAC
TCAAGATGTGTACGCTAAGCTCAACATCATCCCGCATGTCCTGCGTCCAAAAGAAGGCTTAGCCCTGATGAACGGCACCG
CCGTGATGACAGCTTTAGCCTGCTTAGCCTTTGATCGCGCGCAATATCTTGCTCGCTTGAGTAGTCGCATTACCGCCATG
GCTTCGTTAACGCTAAAAGGCAACTCGAACCATTTTGATGAAATCTTATTTGCCGCCAAACCGCATCCAGGGCAAAACCA
AATCGCCACTTGGATACGGGAAGATTTGAATCACCACGAACATCCACGTAATTCTGATCGTCTGCAGGACAGATATTCCA
TCCGCTGCGCACCACACATTATCGGCGTGTTGCAGGATGCCCTGCCGTTTATGCGTCAGTTTATCGAAACCGAAATCAAC
AGCGCCAACGACAACCCGATTGTCGACGGCGAAGGCGAGCATATTCTCCACGGTGGCCATTTCTACGGCGGCCATATCGC
CTTTGCGATGGATTCACTGAAAAATACTGTGGCCAACTTAGCCGATCTTATCGACCGCCAAATGGCGCTAGTAATGGACC
CTAAGTTTAACAATGGCTTACCTGCGAACCTATCCGGCTCAACCGGTCCACGCCGCGCGATTAATCATGGCTTTAAAGCG
GTACAAATTGGCGTGTCGGCTTGGACGGCAGAAGCGCTCAAGCACACTATGCCGGCCAGCGTGTTCTCTCGCTCGACCGA
ATGCCACAACCAAGACAAGGTGAGCATGGGTACTATCGCCGCCCGCGATTGTATGCGCGTGCTGCAATTGACCGAACAAG
TCGCAGCGGCTGCATTACTTGCCATGACCCAAGGTATTGGTCTGCGTATCGCTCAAAATGAACTGAGCGAAGCCTCGCTC
ACACCCTCATTGGCGAAAACCCTCGCTCAAGTGCGCGCCGATTTTGAAACCTTAATTGAAGATAGGCCGCTCGAAACTGT
GCTGCGCCAAACCATAGCTAAAATCCAAGCGGGCGAATGGGAAGTGTGCCGATGA

Upstream 100 bases:

>100_bases
GCACCCCATCGCATTTAGTACAGCCTAATCCGTTACCGACAACTTCAGCATCATCGCCGATCCCAGAGCAGGATCATAAG
ACAGACAGGACACAGCATTC

Downstream 100 bases:

>100_bases
AATCATTGCTCACTATCGATATGGAAATGCAAATCCCCTTCCACGATGTGGATTCTATGAGGATTACTTGGCATGGCAAT
TACCTGCGTTATTTCGAAAT

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: Histidase [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSHTKAADSESQSDLQTVEFGRQFLTLEQVVAVAKGAPVKLCDDADYQEYIQKGARFIDSLLHEEGVVYGVTTGYGDSCT
VNVSLDLVHELPLHLTRFHGCGLGETLSIMQARAVMACRLNSLAIGKSGVTYELLKRIETLLNLNIVPVIPEEGSVGASG
DLTPLSYLAAVLVGEREVIYQGERQATQDVYAKLNIIPHVLRPKEGLALMNGTAVMTALACLAFDRAQYLARLSSRITAM
ASLTLKGNSNHFDEILFAAKPHPGQNQIATWIREDLNHHEHPRNSDRLQDRYSIRCAPHIIGVLQDALPFMRQFIETEIN
SANDNPIVDGEGEHILHGGHFYGGHIAFAMDSLKNTVANLADLIDRQMALVMDPKFNNGLPANLSGSTGPRRAINHGFKA
VQIGVSAWTAEALKHTMPASVFSRSTECHNQDKVSMGTIAARDCMRVLQLTEQVAAAALLAMTQGIGLRIAQNELSEASL
TPSLAKTLAQVRADFETLIEDRPLETVLRQTIAKIQAGEWEVCR

Sequences:

>Translated_524_residues
MSHTKAADSESQSDLQTVEFGRQFLTLEQVVAVAKGAPVKLCDDADYQEYIQKGARFIDSLLHEEGVVYGVTTGYGDSCT
VNVSLDLVHELPLHLTRFHGCGLGETLSIMQARAVMACRLNSLAIGKSGVTYELLKRIETLLNLNIVPVIPEEGSVGASG
DLTPLSYLAAVLVGEREVIYQGERQATQDVYAKLNIIPHVLRPKEGLALMNGTAVMTALACLAFDRAQYLARLSSRITAM
ASLTLKGNSNHFDEILFAAKPHPGQNQIATWIREDLNHHEHPRNSDRLQDRYSIRCAPHIIGVLQDALPFMRQFIETEIN
SANDNPIVDGEGEHILHGGHFYGGHIAFAMDSLKNTVANLADLIDRQMALVMDPKFNNGLPANLSGSTGPRRAINHGFKA
VQIGVSAWTAEALKHTMPASVFSRSTECHNQDKVSMGTIAARDCMRVLQLTEQVAAAALLAMTQGIGLRIAQNELSEASL
TPSLAKTLAQVRADFETLIEDRPLETVLRQTIAKIQAGEWEVCR
>Mature_523_residues
SHTKAADSESQSDLQTVEFGRQFLTLEQVVAVAKGAPVKLCDDADYQEYIQKGARFIDSLLHEEGVVYGVTTGYGDSCTV
NVSLDLVHELPLHLTRFHGCGLGETLSIMQARAVMACRLNSLAIGKSGVTYELLKRIETLLNLNIVPVIPEEGSVGASGD
LTPLSYLAAVLVGEREVIYQGERQATQDVYAKLNIIPHVLRPKEGLALMNGTAVMTALACLAFDRAQYLARLSSRITAMA
SLTLKGNSNHFDEILFAAKPHPGQNQIATWIREDLNHHEHPRNSDRLQDRYSIRCAPHIIGVLQDALPFMRQFIETEINS
ANDNPIVDGEGEHILHGGHFYGGHIAFAMDSLKNTVANLADLIDRQMALVMDPKFNNGLPANLSGSTGPRRAINHGFKAV
QIGVSAWTAEALKHTMPASVFSRSTECHNQDKVSMGTIAARDCMRVLQLTEQVAAAALLAMTQGIGLRIAQNELSEASLT
PSLAKTLAQVRADFETLIEDRPLETVLRQTIAKIQAGEWEVCR

Specific function: Unknown

COG id: COG2986

COG function: function code E; Histidine ammonia-lyase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAL/histidase family [H]

Homologues:

Organism=Homo sapiens, GI4504333, Length=496, Percent_Identity=37.0967741935484, Blast_Score=295, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17567831, Length=485, Percent_Identity=36.0824742268041, Blast_Score=260, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005921
- InterPro:   IPR008948
- InterPro:   IPR001106
- InterPro:   IPR022313 [H]

Pfam domain/function: PF00221 PAL [H]

EC number: =4.3.1.3 [H]

Molecular weight: Translated: 57249; Mature: 57118

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00488 PAL_HISTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTKAADSESQSDLQTVEFGRQFLTLEQVVAVAKGAPVKLCDDADYQEYIQKGARFIDS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
LLHEEGVVYGVTTGYGDSCTVNVSLDLVHELPLHLTRFHGCGLGETLSIMQARAVMACRL
HHHHCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NSLAIGKSGVTYELLKRIETLLNLNIVPVIPEEGSVGASGDLTPLSYLAAVLVGEREVIY
CHHEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHEE
QGERQATQDVYAKLNIIPHVLRPKEGLALMNGTAVMTALACLAFDRAQYLARLSSRITAM
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLTLKGNSNHFDEILFAAKPHPGQNQIATWIREDLNHHEHPRNSDRLQDRYSIRCAPHI
HEEEEECCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IGVLQDALPFMRQFIETEINSANDNPIVDGEGEHILHGGHFYGGHIAFAMDSLKNTVANL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEECCHHHHHHHHHHHHHHHH
ADLIDRQMALVMDPKFNNGLPANLSGSTGPRRAINHGFKAVQIGVSAWTAEALKHTMPAS
HHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHCCHH
VFSRSTECHNQDKVSMGTIAARDCMRVLQLTEQVAAAALLAMTQGIGLRIAQNELSEASL
HHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
TPSLAKTLAQVRADFETLIEDRPLETVLRQTIAKIQAGEWEVCR
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SHTKAADSESQSDLQTVEFGRQFLTLEQVVAVAKGAPVKLCDDADYQEYIQKGARFIDS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHH
LLHEEGVVYGVTTGYGDSCTVNVSLDLVHELPLHLTRFHGCGLGETLSIMQARAVMACRL
HHHHCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
NSLAIGKSGVTYELLKRIETLLNLNIVPVIPEEGSVGASGDLTPLSYLAAVLVGEREVIY
CHHEECCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCHHHEE
QGERQATQDVYAKLNIIPHVLRPKEGLALMNGTAVMTALACLAFDRAQYLARLSSRITAM
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLTLKGNSNHFDEILFAAKPHPGQNQIATWIREDLNHHEHPRNSDRLQDRYSIRCAPHI
HEEEEECCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IGVLQDALPFMRQFIETEINSANDNPIVDGEGEHILHGGHFYGGHIAFAMDSLKNTVANL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCEECCHHHHHHHHHHHHHHHH
ADLIDRQMALVMDPKFNNGLPANLSGSTGPRRAINHGFKAVQIGVSAWTAEALKHTMPAS
HHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHCCHH
VFSRSTECHNQDKVSMGTIAARDCMRVLQLTEQVAAAALLAMTQGIGLRIAQNELSEASL
HHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
TPSLAKTLAQVRADFETLIEDRPLETVLRQTIAKIQAGEWEVCR
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA