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The map label for this gene is degS [H]

Identifier: 159901421

GI number: 159901421

Start: 6248870

End: 6249913

Strand: Reverse

Name: degS [H]

Synonym: Haur_4910

Alternate gene names: 159901421

Gene position: 6249913-6248870 (Counterclockwise)

Preceding gene: 159901422

Following gene: 159901415

Centisome position: 98.48

GC content: 47.22

Gene sequence:

>1044_bases
ATGGCAGCCGACAAAGACGCATTATTAAAAGAATTGCGTGACCAACAAGACCGCATTCGTCGCCAAATGACCGAACTTGA
TGCCTTGGTTCGCCAAAATCAAGCTGAAGTCGATAAAATGTCGCAACGTGAAATGTCGGTTTCCAGTCGCCGTCGCGATA
TGGAAGTCAATTTCGAGCGCTATGAAAAAGTTGATATTAAAAATTTCTACACTTCGGCCCAAGAGGTTCAAACCCGTGTC
CAAATGATGCGCAGCCAAGTGGAGCAACTGCAAACTAAACAACAAGTGCTGCGCGAACAACAAGATACGCTGCAAAAACT
GATTCAAAGCCTCGATGAGGTCAGCGTTGTGGCCGAAACAACCATTTCAAACTTGCCACACGTTAATCCACAAGAACAAA
TTGCCGCGATTATTCAAGCCCAAGAAAAGGAGCGCCTGCGGATTTCGTTGCAAATGCACGATGGCCCAGCTCAATCGATG
AGTAACTTGGTGTTACGCGCCGAAATTTGCGAACGCTTCCTTGATCACGATACCAATCAGGCTCGTTCAGAGATGTCTAG
CCTCAAAACGGCGATCAATACTGTGTTGCAAGATACACGGCGTTTTATCTTCGATTTACGCCCGATGACCCTTGACGATT
TAGGGTTGTTGCCAACGCTCAAGCGTTATAGCCAAGAATTTGGCGATAAAAACAATATCGAGATCAATTTAATGGTACAA
GGTTTGGAAACCCGCTTGCCTAGTCATTATGAAGTAACGATTTTCCGTTTTGTCCAAGAAGCGCTGAATAACGTGCAACG
CCACGCCAATGCTTCGCATGTCCGAATTATCCTTGAGGCTGATGCTAGCCGCATTCAAATTGCGATTGAGGACGATGGGG
CTGGCTTCCATGTTGCCGAAACCCTCAACGACCCAACAGGTAAACGCAATATGGGGATAGCCAGCTTACGTCAACAGGCC
GAAGTGCTCTTACGTGGCCAAATGGGCATAGAAAGCACTGTAGGCAGGGGTACTCGGGTTGTAGCAGTCGTACCTTCACC
CTAA

Upstream 100 bases:

>100_bases
TCCAACGCCGTTTTAGTGCTGCGTCGCTGGGTATAATTGACGCAGTAAAATCGCCACCAGTATAATTTCATTCACGCACC
ACCATCGAATTGGAGGGCTT

Downstream 100 bases:

>100_bases
TCACCTATCTTGATAGGACTAACATCCTATTGGCATTCAAACTATCGTCGGATATGATGTCCACATCGTAATCAATATTT
CTCTCGTAAGGAGATACTGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MAADKDALLKELRDQQDRIRRQMTELDALVRQNQAEVDKMSQREMSVSSRRRDMEVNFERYEKVDIKNFYTSAQEVQTRV
QMMRSQVEQLQTKQQVLREQQDTLQKLIQSLDEVSVVAETTISNLPHVNPQEQIAAIIQAQEKERLRISLQMHDGPAQSM
SNLVLRAEICERFLDHDTNQARSEMSSLKTAINTVLQDTRRFIFDLRPMTLDDLGLLPTLKRYSQEFGDKNNIEINLMVQ
GLETRLPSHYEVTIFRFVQEALNNVQRHANASHVRIILEADASRIQIAIEDDGAGFHVAETLNDPTGKRNMGIASLRQQA
EVLLRGQMGIESTVGRGTRVVAVVPSP

Sequences:

>Translated_347_residues
MAADKDALLKELRDQQDRIRRQMTELDALVRQNQAEVDKMSQREMSVSSRRRDMEVNFERYEKVDIKNFYTSAQEVQTRV
QMMRSQVEQLQTKQQVLREQQDTLQKLIQSLDEVSVVAETTISNLPHVNPQEQIAAIIQAQEKERLRISLQMHDGPAQSM
SNLVLRAEICERFLDHDTNQARSEMSSLKTAINTVLQDTRRFIFDLRPMTLDDLGLLPTLKRYSQEFGDKNNIEINLMVQ
GLETRLPSHYEVTIFRFVQEALNNVQRHANASHVRIILEADASRIQIAIEDDGAGFHVAETLNDPTGKRNMGIASLRQQA
EVLLRGQMGIESTVGRGTRVVAVVPSP
>Mature_346_residues
AADKDALLKELRDQQDRIRRQMTELDALVRQNQAEVDKMSQREMSVSSRRRDMEVNFERYEKVDIKNFYTSAQEVQTRVQ
MMRSQVEQLQTKQQVLREQQDTLQKLIQSLDEVSVVAETTISNLPHVNPQEQIAAIIQAQEKERLRISLQMHDGPAQSMS
NLVLRAEICERFLDHDTNQARSEMSSLKTAINTVLQDTRRFIFDLRPMTLDDLGLLPTLKRYSQEFGDKNNIEINLMVQG
LETRLPSHYEVTIFRFVQEALNNVQRHANASHVRIILEADASRIQIAIEDDGAGFHVAETLNDPTGKRNMGIASLRQQAE
VLLRGQMGIESTVGRGTRVVAVVPSP

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=199, Percent_Identity=25.1256281407035, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39721; Mature: 39590

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADKDALLKELRDQQDRIRRQMTELDALVRQNQAEVDKMSQREMSVSSRRRDMEVNFER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
YEKVDIKNFYTSAQEVQTRVQMMRSQVEQLQTKQQVLREQQDTLQKLIQSLDEVSVVAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TISNLPHVNPQEQIAAIIQAQEKERLRISLQMHDGPAQSMSNLVLRAEICERFLDHDTNQ
HHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHH
ARSEMSSLKTAINTVLQDTRRFIFDLRPMTLDDLGLLPTLKRYSQEFGDKNNIEINLMVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEEEEE
GLETRLPSHYEVTIFRFVQEALNNVQRHANASHVRIILEADASRIQIAIEDDGAGFHVAE
EHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCEEEHH
TLNDPTGKRNMGIASLRQQAEVLLRGQMGIESTVGRGTRVVAVVPSP
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEECCC
>Mature Secondary Structure 
AADKDALLKELRDQQDRIRRQMTELDALVRQNQAEVDKMSQREMSVSSRRRDMEVNFER
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
YEKVDIKNFYTSAQEVQTRVQMMRSQVEQLQTKQQVLREQQDTLQKLIQSLDEVSVVAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TISNLPHVNPQEQIAAIIQAQEKERLRISLQMHDGPAQSMSNLVLRAEICERFLDHDTNQ
HHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHH
ARSEMSSLKTAINTVLQDTRRFIFDLRPMTLDDLGLLPTLKRYSQEFGDKNNIEINLMVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHCCCCCCEEEEEEEE
GLETRLPSHYEVTIFRFVQEALNNVQRHANASHVRIILEADASRIQIAIEDDGAGFHVAE
EHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCEEEHH
TLNDPTGKRNMGIASLRQQAEVLLRGQMGIESTVGRGTRVVAVVPSP
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]