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The map label for this gene is xerC

Identifier: 159901208

GI number: 159901208

Start: 5999673

End: 6000593

Strand: Direct

Name: xerC

Synonym: Haur_4696

Alternate gene names: 159901208

Gene position: 5999673-6000593 (Clockwise)

Preceding gene: 159901207

Following gene: 159901209

Centisome position: 94.53

GC content: 51.68

Gene sequence:

>921_bases
ATGCAGCAGCAGCTAGAACAGTTTTTGGCCTATTTAACGGTTGAGCGCGGTTTGACCGGTAACACAATTGCCGCCTACCG
AACCGATCTTGACCAATTTGTTAACTTTATTGTTGAACGTAACACAGGCAGTTGGAGCAACGTCTCCCGCGATGACCTGT
TGGCGTTCTTGCTCTTTCTCAAAGAAAAGCGCTACGCAACCTCCACGATCGCACGTCGTACTGCTGCAATTAAATCGTTT
TTTGAATACCTGCAAGGCCAGCATAGTATCACCACGAATCCAACTGAAAACTTGGATTCACCCAAGGTTGATCGGTTCTT
GCCCAAGGCAATTACGGTCGCCCAAGTTGATGAACTGCTTGAGTTACCTTTGACCACCAGCGGCCCTGAAGGCTTGCGCG
ATAAAGCCATGCTCGAAGTGTTGTATGCCACTGGCATGCGCGTTAGCGAGTTGGTTGCGCTCGATGTGGGCGATGTTGAT
CTGGCGATCCACCAGATTCGCTGCTTGGGCAAGGCCAATAAAGAGCGGAATCTGCCGATTGTTGGCAGCGCCAGCACCGC
CTTGGAAGAATATCTCGATATTGCCCGTGGCCAAATTAGCCGTAACGGCGGCGATCCAGCCTTGTTTCTCAATCACCGTG
GTAAGCGGCTTACCCGCCAAGGCTTTTGGTTGATTTTGAAGGGCTACGCCGAACGCTTGGGGCTGAGCGATCTGACACCG
CATACCTTGCGCCACTCGTTCGCAACCCACATGCTCAACCGTGGCAAAGATCTGCGCGAGGTGCAAGAGTTGCTGGGCCA
TGCAAGTATTTCAACAACGCAAATTTATACCCACGTAAGCAACGACCGAGCCGTTAAATACGATCAAGCAGCCCAACGAC
CAACAGTCGCCAATGCTGCTGAAGTCGAATTTAGCGCCTAA

Upstream 100 bases:

>100_bases
TCCCCAACAATCAATCATCTTTGACATAAGCAATTCTTGGTGCTACCATAGGCGCTGCGGGGAATTTTGGAAACGCATAT
CCCGACGTTGGAGGGTGCTC

Downstream 100 bases:

>100_bases
TCAAATCAGTCGTTGGACTGAACGCAAGCATTGACAACAATGCTACAGTAGCAGCCAACAACGTGATTCATCTTGGTGAT
GAACCGTAGAAGTAGCTTGG

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MQQQLEQFLAYLTVERGLTGNTIAAYRTDLDQFVNFIVERNTGSWSNVSRDDLLAFLLFLKEKRYATSTIARRTAAIKSF
FEYLQGQHSITTNPTENLDSPKVDRFLPKAITVAQVDELLELPLTTSGPEGLRDKAMLEVLYATGMRVSELVALDVGDVD
LAIHQIRCLGKANKERNLPIVGSASTALEEYLDIARGQISRNGGDPALFLNHRGKRLTRQGFWLILKGYAERLGLSDLTP
HTLRHSFATHMLNRGKDLREVQELLGHASISTTQIYTHVSNDRAVKYDQAAQRPTVANAAEVEFSA

Sequences:

>Translated_306_residues
MQQQLEQFLAYLTVERGLTGNTIAAYRTDLDQFVNFIVERNTGSWSNVSRDDLLAFLLFLKEKRYATSTIARRTAAIKSF
FEYLQGQHSITTNPTENLDSPKVDRFLPKAITVAQVDELLELPLTTSGPEGLRDKAMLEVLYATGMRVSELVALDVGDVD
LAIHQIRCLGKANKERNLPIVGSASTALEEYLDIARGQISRNGGDPALFLNHRGKRLTRQGFWLILKGYAERLGLSDLTP
HTLRHSFATHMLNRGKDLREVQELLGHASISTTQIYTHVSNDRAVKYDQAAQRPTVANAAEVEFSA
>Mature_306_residues
MQQQLEQFLAYLTVERGLTGNTIAAYRTDLDQFVNFIVERNTGSWSNVSRDDLLAFLLFLKEKRYATSTIARRTAAIKSF
FEYLQGQHSITTNPTENLDSPKVDRFLPKAITVAQVDELLELPLTTSGPEGLRDKAMLEVLYATGMRVSELVALDVGDVD
LAIHQIRCLGKANKERNLPIVGSASTALEEYLDIARGQISRNGGDPALFLNHRGKRLTRQGFWLILKGYAERLGLSDLTP
HTLRHSFATHMLNRGKDLREVQELLGHASISTTQIYTHVSNDRAVKYDQAAQRPTVANAAEVEFSA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=288, Percent_Identity=44.0972222222222, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=39.3220338983051, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=29.1208791208791, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790768, Length=154, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_HERA2 (A9B1E0)

Other databases:

- EMBL:   CP000875
- RefSeq:   YP_001547455.1
- ProteinModelPortal:   A9B1E0
- SMR:   A9B1E0
- GeneID:   5736543
- GenomeReviews:   CP000875_GR
- KEGG:   hau:Haur_4696
- HOGENOM:   HBG727654
- OMA:   YLEYGRP
- ProtClustDB:   CLSK973200
- BioCyc:   HAUR316274:HAUR_4696-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 34204; Mature: 34204

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: ACT_SITE 147-147 ACT_SITE 171-171 ACT_SITE 241-241 ACT_SITE 244-244 ACT_SITE 267-267 ACT_SITE 276-276

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQLEQFLAYLTVERGLTGNTIAAYRTDLDQFVNFIVERNTGSWSNVSRDDLLAFLLFL
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
KEKRYATSTIARRTAAIKSFFEYLQGQHSITTNPTENLDSPKVDRFLPKAITVAQVDELL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELPLTTSGPEGLRDKAMLEVLYATGMRVSELVALDVGDVDLAIHQIRCLGKANKERNLPI
HCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCE
VGSASTALEEYLDIARGQISRNGGDPALFLNHRGKRLTRQGFWLILKGYAERLGLSDLTP
ECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHCCCCCCCH
HTLRHSFATHMLNRGKDLREVQELLGHASISTTQIYTHVSNDRAVKYDQAAQRPTVANAA
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCEECHHHHCCCCCCCCC
EVEFSA
CCEECC
>Mature Secondary Structure
MQQQLEQFLAYLTVERGLTGNTIAAYRTDLDQFVNFIVERNTGSWSNVSRDDLLAFLLFL
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
KEKRYATSTIARRTAAIKSFFEYLQGQHSITTNPTENLDSPKVDRFLPKAITVAQVDELL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELPLTTSGPEGLRDKAMLEVLYATGMRVSELVALDVGDVDLAIHQIRCLGKANKERNLPI
HCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCE
VGSASTALEEYLDIARGQISRNGGDPALFLNHRGKRLTRQGFWLILKGYAERLGLSDLTP
ECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHCCHHHHHHHHHHHCCCCCCCH
HTLRHSFATHMLNRGKDLREVQELLGHASISTTQIYTHVSNDRAVKYDQAAQRPTVANAA
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCEECHHHHCCCCCCCCC
EVEFSA
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA