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The map label for this gene is phoP [H]

Identifier: 159901175

GI number: 159901175

Start: 5960675

End: 5961373

Strand: Direct

Name: phoP [H]

Synonym: Haur_4663

Alternate gene names: 159901175

Gene position: 5960675-5961373 (Clockwise)

Preceding gene: 159901174

Following gene: 159901176

Centisome position: 93.92

GC content: 56.37

Gene sequence:

>699_bases
ATGGCCAATATTTTGGTGGTTGATGACGAACCGAATATTCGCGAAGTGGTAGGCTTGTATTTGCGGCGCGAAGGCCATAC
GGTGCTTGAGGCCAGCGATGGCGAGGCCGCTTTGCGCTTGGCGCGTCAGCAACCACCCGATTTGGTCGTGCTTGATCTGA
TGTTGCCCAAAGTGACTGGCTTAGAAGTTTGTCGGCGCTTGCAGAGCGATCGCCGCACGCCAGTGATTATGCTCACCGCC
AAGAGCGAGGAGAACGATCGCATCATTGGCCTCGGGGTTGGTGCTGATGATTATGTGGTCAAGCCATTTAGCCCACGCGA
ATTGGTGGCCCGGGTGGAAGCGGTGTTGCGCCGTGTTCAGCCGCAGCCCGATGCTCCACCACCCGACGAACGCCCAATTG
AACTTGGCGCACTGCGGGTCGATCCGCGCACTCGTGATGTGCAAGTGGCGGGCAAATCGATCAGCCTAACTGCGCGTGAG
TTTGATTTGCTCTATTTTTTGGCACGCCATCGCGAGCGTGTGTTTACCCGCGACCAACTGATGGAACTCGTTTGGGGCTA
TACATTTTCTGCCGATACCAGCACCGTGACGGTGCATATTCGGCGCTTGCGCGAAAAAATCGAAGACGATCCGACTGCCC
CGCGTTATTTGCAAACAGTTTGGGGCGTGGGCTACAAACTCAGCGCAGGCGAACAATGA

Upstream 100 bases:

>100_bases
TGGGGCAATCTGTGGCGAAACAACAGCCCTTCGTGTCCTTCGTGGATCAATATTCTAATCCCTGACTCCTAGCCCCTGAA
CCCTAAAAAAAGGATGAGGT

Downstream 100 bases:

>100_bases
GACGTTTTTTGCATCAATCGAGCCTTTTGTTGTTGACCTTGGCGATTGCTCTGGGCTTGGTAAGTTTGGTCGGTCACTTT
GGCTTGATGCTGCCAATGAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MANILVVDDEPNIREVVGLYLRREGHTVLEASDGEAALRLARQQPPDLVVLDLMLPKVTGLEVCRRLQSDRRTPVIMLTA
KSEENDRIIGLGVGADDYVVKPFSPRELVARVEAVLRRVQPQPDAPPPDERPIELGALRVDPRTRDVQVAGKSISLTARE
FDLLYFLARHRERVFTRDQLMELVWGYTFSADTSTVTVHIRRLREKIEDDPTAPRYLQTVWGVGYKLSAGEQ

Sequences:

>Translated_232_residues
MANILVVDDEPNIREVVGLYLRREGHTVLEASDGEAALRLARQQPPDLVVLDLMLPKVTGLEVCRRLQSDRRTPVIMLTA
KSEENDRIIGLGVGADDYVVKPFSPRELVARVEAVLRRVQPQPDAPPPDERPIELGALRVDPRTRDVQVAGKSISLTARE
FDLLYFLARHRERVFTRDQLMELVWGYTFSADTSTVTVHIRRLREKIEDDPTAPRYLQTVWGVGYKLSAGEQ
>Mature_231_residues
ANILVVDDEPNIREVVGLYLRREGHTVLEASDGEAALRLARQQPPDLVVLDLMLPKVTGLEVCRRLQSDRRTPVIMLTAK
SEENDRIIGLGVGADDYVVKPFSPRELVARVEAVLRRVQPQPDAPPPDERPIELGALRVDPRTRDVQVAGKSISLTAREF
DLLYFLARHRERVFTRDQLMELVWGYTFSADTSTVTVHIRRLREKIEDDPTAPRYLQTVWGVGYKLSAGEQ

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=45.3333333333333, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=43.2314410480349, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=40.0881057268723, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=38.4955752212389, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=39.5555555555556, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=37.4449339207048, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=37.8260869565217, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=38.4955752212389, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=32.3008849557522, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.8701298701299, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=30.0429184549356, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=32.3144104803493, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=35.042735042735, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.5991189427313, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=36.5217391304348, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26276; Mature: 26144

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILVVDDEPNIREVVGLYLRREGHTVLEASDGEAALRLARQQPPDLVVLDLMLPKVTG
CCCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCH
LEVCRRLQSDRRTPVIMLTAKSEENDRIIGLGVGADDYVVKPFSPRELVARVEAVLRRVQ
HHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCC
PQPDAPPPDERPIELGALRVDPRTRDVQVAGKSISLTAREFDLLYFLARHRERVFTRDQL
CCCCCCCCCCCCEEEEEEEECCCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
MELVWGYTFSADTSTVTVHIRRLREKIEDDPTAPRYLQTVWGVGYKLSAGEQ
HHHHHCCEECCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure 
ANILVVDDEPNIREVVGLYLRREGHTVLEASDGEAALRLARQQPPDLVVLDLMLPKVTG
CCEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCH
LEVCRRLQSDRRTPVIMLTAKSEENDRIIGLGVGADDYVVKPFSPRELVARVEAVLRRVQ
HHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHCC
PQPDAPPPDERPIELGALRVDPRTRDVQVAGKSISLTAREFDLLYFLARHRERVFTRDQL
CCCCCCCCCCCCEEEEEEEECCCCCEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
MELVWGYTFSADTSTVTVHIRRLREKIEDDPTAPRYLQTVWGVGYKLSAGEQ
HHHHHCCEECCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]