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The map label for this gene is cymR [H]

Identifier: 159899482

GI number: 159899482

Start: 3738625

End: 3739053

Strand: Reverse

Name: cymR [H]

Synonym: Haur_2963

Alternate gene names: 159899482

Gene position: 3739053-3738625 (Counterclockwise)

Preceding gene: 159899483

Following gene: 159899481

Centisome position: 58.91

GC content: 49.18

Gene sequence:

>429_bases
ATGCGATTATCAACCAAAGGTGAATATGGCGTGCGAGCGTTATTTGATTTGGCTCAGCACTATGGCGAGGGTTTGGTGCA
AAGCCACGAAATTGCCGAGCGTCAAGCTATCTCAGAAAATTATCTCAATCAATTGTTAATCGCATTGCGCAAAGCTGGCC
TAATTACCAGCGTGCGTGGCCCTCAAGGTGGTCATCAGTTGGCTCGCCCTCCCCAAGCAATTAGCTTGCTTGATGCTATT
TTGGTATTGGAAGGGCCATTGTTGCCAACACCCGAAGGCGCAAGCCTCGATACTTTTGATGCTGGTTTGTTGGGCGAAGT
TTGGGGCGAATTACGCGCCGTGATCGAAGGCCATCTCAGCGAAATGACCATCGCCGATCTCTGTCAACGCAAACACCAGC
AACTCGATTCGCCGATGTATTATATTTAG

Upstream 100 bases:

>100_bases
GGTGGCGACCAATTTAAAAGGCTCGCTTTTGACTTCTCTGGCCCCTAATGCTAGCATGGCGGCTATCTGAATTGATTGTA
TATAGCAGCAATGAGGCAGA

Downstream 100 bases:

>100_bases
GGATCAGGGGTAGGGGATTAGGGGTCAGAATTTAGGCTGATTTTACAATTGATCTTTTTTTTACATTCCTCGAACTAATC
CCTGGCATCTGACCCCTGAC

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MRLSTKGEYGVRALFDLAQHYGEGLVQSHEIAERQAISENYLNQLLIALRKAGLITSVRGPQGGHQLARPPQAISLLDAI
LVLEGPLLPTPEGASLDTFDAGLLGEVWGELRAVIEGHLSEMTIADLCQRKHQQLDSPMYYI

Sequences:

>Translated_142_residues
MRLSTKGEYGVRALFDLAQHYGEGLVQSHEIAERQAISENYLNQLLIALRKAGLITSVRGPQGGHQLARPPQAISLLDAI
LVLEGPLLPTPEGASLDTFDAGLLGEVWGELRAVIEGHLSEMTIADLCQRKHQQLDSPMYYI
>Mature_142_residues
MRLSTKGEYGVRALFDLAQHYGEGLVQSHEIAERQAISENYLNQLLIALRKAGLITSVRGPQGGHQLARPPQAISLLDAI
LVLEGPLLPTPEGASLDTFDAGLLGEVWGELRAVIEGHLSEMTIADLCQRKHQQLDSPMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=133, Percent_Identity=34.5864661654135, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15572; Mature: 15572

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSTKGEYGVRALFDLAQHYGEGLVQSHEIAERQAISENYLNQLLIALRKAGLITSVRG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
PQGGHQLARPPQAISLLDAILVLEGPLLPTPEGASLDTFDAGLLGEVWGELRAVIEGHLS
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EMTIADLCQRKHQQLDSPMYYI
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLSTKGEYGVRALFDLAQHYGEGLVQSHEIAERQAISENYLNQLLIALRKAGLITSVRG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
PQGGHQLARPPQAISLLDAILVLEGPLLPTPEGASLDTFDAGLLGEVWGELRAVIEGHLS
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EMTIADLCQRKHQQLDSPMYYI
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]