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The map label for this gene is nrdB [H]

Identifier: 159899093

GI number: 159899093

Start: 3299808

End: 3300836

Strand: Reverse

Name: nrdB [H]

Synonym: Haur_2574

Alternate gene names: 159899093

Gene position: 3300836-3299808 (Counterclockwise)

Preceding gene: 159899094

Following gene: 159899092

Centisome position: 52.01

GC content: 41.89

Gene sequence:

>1029_bases
ATGACTGAACAATTTGGCCGCTTTAATGCCAGCGATAAACGCCTGATCAATTGTAATCAAGTTGATGTAAACCAATTAAT
GCCGTTGCGCTATGGCTGGGCTTGGGAGCATTATCTGAATGGTTGTGCGAACCACTGGATGCCCAACGAAGTTTCGATGA
CTGGTGATATTGCAATTTGGCGCTCAACGAGTCTATCAGCTGATGAACGCTTGATGGTATTGCGCAATTTAGGCTTTTTT
GCGACAGCAGAAAGTTTAGTTGGCAACAATATTGTTTTGGCGATTTTTCGACATATTACCAACGCCGAATGTCGTCAATA
TTTATTACGCCAAGCTTTTGAAGAAGCGATTCATACCCACGCATTTTTGCATATTGTCGAAAGCTTGGGCCTGAATGAAC
GTGAAATCTTCAATATGTATCATGAAATTCCAGTTATTAGCCAAAAAGATCAGTTTGAGATGCAATTAACTGCGGCGGTG
CTCGACCCACAATTTAGCACTGAAACGCTCACAGGGATGCAAACCTTCGTTAAAAATCTAATTGGCTATTATGTGATTAT
GGAAGGGATTTTCTTCTATAGCGGTTTTGCAATGCTGCTTTCATTACATCGCCGCAATGTACTGACGGGCATTGGTGAGC
AAATTCAATATATTTTACGCGATGAAACAATTCACCTGAATTTTGGGGTCGATTTGATTAATGGAATCAAAGCTGAAAAC
CCAGCAATTTGGACAAACGAATTTCAAGCTGAGATTGTGCAATTAATTCGCCAATCAGTTGAATTAGAAGCTCAATATGC
TGCTGAATGCTTGCCGCGTGGAGTAATGGGCTTGCATGCAGCAATGTTCCGCGATTATGTGCAATATATCGCCGACCGCC
GTCTGCAACGGATTGGTTTAGCGATTCAATATGGCTCACAAAATCCATTTCCATGGATGAGTGAAACGATCGATTTGACC
AAGGAGAAGAATTTCTTTGAGACGCGGGTCACTGAATATCAATCAGCGGCCAGTCTAGAATGGGATTAA

Upstream 100 bases:

>100_bases
TGGATGCGCAACCGCAGCGAATCGGCCAGCGTGCTGAGCGATAACGTTTGTCCAATCGATGACCCTAGTTGCGAAGCCTG
TGAGTAGCGAGGAATGTTGC

Downstream 100 bases:

>100_bases
GCATGAATTTTCAAACAACAGTTGTGGGTTATCCACGGGTTGGCGTTGGCCGGCCATACAAGCAGGCTTTGGAACGCTTT
TGGAGTGGCAAACTCGATGA

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTEQFGRFNASDKRLINCNQVDVNQLMPLRYGWAWEHYLNGCANHWMPNEVSMTGDIAIWRSTSLSADERLMVLRNLGFF
ATAESLVGNNIVLAIFRHITNAECRQYLLRQAFEEAIHTHAFLHIVESLGLNEREIFNMYHEIPVISQKDQFEMQLTAAV
LDPQFSTETLTGMQTFVKNLIGYYVIMEGIFFYSGFAMLLSLHRRNVLTGIGEQIQYILRDETIHLNFGVDLINGIKAEN
PAIWTNEFQAEIVQLIRQSVELEAQYAAECLPRGVMGLHAAMFRDYVQYIADRRLQRIGLAIQYGSQNPFPWMSETIDLT
KEKNFFETRVTEYQSAASLEWD

Sequences:

>Translated_342_residues
MTEQFGRFNASDKRLINCNQVDVNQLMPLRYGWAWEHYLNGCANHWMPNEVSMTGDIAIWRSTSLSADERLMVLRNLGFF
ATAESLVGNNIVLAIFRHITNAECRQYLLRQAFEEAIHTHAFLHIVESLGLNEREIFNMYHEIPVISQKDQFEMQLTAAV
LDPQFSTETLTGMQTFVKNLIGYYVIMEGIFFYSGFAMLLSLHRRNVLTGIGEQIQYILRDETIHLNFGVDLINGIKAEN
PAIWTNEFQAEIVQLIRQSVELEAQYAAECLPRGVMGLHAAMFRDYVQYIADRRLQRIGLAIQYGSQNPFPWMSETIDLT
KEKNFFETRVTEYQSAASLEWD
>Mature_341_residues
TEQFGRFNASDKRLINCNQVDVNQLMPLRYGWAWEHYLNGCANHWMPNEVSMTGDIAIWRSTSLSADERLMVLRNLGFFA
TAESLVGNNIVLAIFRHITNAECRQYLLRQAFEEAIHTHAFLHIVESLGLNEREIFNMYHEIPVISQKDQFEMQLTAAVL
DPQFSTETLTGMQTFVKNLIGYYVIMEGIFFYSGFAMLLSLHRRNVLTGIGEQIQYILRDETIHLNFGVDLINGIKAENP
AIWTNEFQAEIVQLIRQSVELEAQYAAECLPRGVMGLHAAMFRDYVQYIADRRLQRIGLAIQYGSQNPFPWMSETIDLTK
EKNFFETRVTEYQSAASLEWD

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI42544136, Length=317, Percent_Identity=25.2365930599369, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI289177074, Length=317, Percent_Identity=25.2365930599369, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI4557845, Length=312, Percent_Identity=25.3205128205128, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI260064013, Length=312, Percent_Identity=25.3205128205128, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI289177076, Length=294, Percent_Identity=25.1700680272109, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17551968, Length=312, Percent_Identity=26.9230769230769, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193206379, Length=302, Percent_Identity=25.8278145695364, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567153, Length=157, Percent_Identity=33.1210191082803, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6322434, Length=318, Percent_Identity=28.3018867924528, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6321619, Length=315, Percent_Identity=22.2222222222222, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI18079279, Length=312, Percent_Identity=26.2820512820513, Blast_Score=130, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 39533; Mature: 39401

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQFGRFNASDKRLINCNQVDVNQLMPLRYGWAWEHYLNGCANHWMPNEVSMTGDIAIW
CCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
RSTSLSADERLMVLRNLGFFATAESLVGNNIVLAIFRHITNAECRQYLLRQAFEEAIHTH
ECCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AFLHIVESLGLNEREIFNMYHEIPVISQKDQFEMQLTAAVLDPQFSTETLTGMQTFVKNL
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IGYYVIMEGIFFYSGFAMLLSLHRRNVLTGIGEQIQYILRDETIHLNFGVDLINGIKAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCC
PAIWTNEFQAEIVQLIRQSVELEAQYAAECLPRGVMGLHAAMFRDYVQYIADRRLQRIGL
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
AIQYGSQNPFPWMSETIDLTKEKNFFETRVTEYQSAASLEWD
EEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEQFGRFNASDKRLINCNQVDVNQLMPLRYGWAWEHYLNGCANHWMPNEVSMTGDIAIW
CCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
RSTSLSADERLMVLRNLGFFATAESLVGNNIVLAIFRHITNAECRQYLLRQAFEEAIHTH
ECCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
AFLHIVESLGLNEREIFNMYHEIPVISQKDQFEMQLTAAVLDPQFSTETLTGMQTFVKNL
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IGYYVIMEGIFFYSGFAMLLSLHRRNVLTGIGEQIQYILRDETIHLNFGVDLINGIKAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHCCCCCCC
PAIWTNEFQAEIVQLIRQSVELEAQYAAECLPRGVMGLHAAMFRDYVQYIADRRLQRIGL
CCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
AIQYGSQNPFPWMSETIDLTKEKNFFETRVTEYQSAASLEWD
EEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]