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The map label for this gene is ubiE [C]

Identifier: 159898623

GI number: 159898623

Start: 2627462

End: 2628271

Strand: Reverse

Name: ubiE [C]

Synonym: Haur_2102

Alternate gene names: 159898623

Gene position: 2628271-2627462 (Counterclockwise)

Preceding gene: 159898624

Following gene: 159898622

Centisome position: 41.41

GC content: 52.47

Gene sequence:

>810_bases
ATGACAACTACCGATTGGGGCGCAATCGATCAAACCAGTGCTGCCCCCACCCATTGTATTGGCTATCTCAACACGGTCAG
CGAGCTTGACCAAGTGGCGCAATATAAGGCCATGACCTTTGAATTACTGGATCTACAACTAGGCCAGCGGGTGCTTGATG
TAGGCTGTGGGGCGGGCAACGATGCTCGCTCGATCGCCCAGCGAGTTGGCGCTGAAGGGCTGGTGATTGGGCTTGATAAT
AGCGAAGCTATGCTGACAAGCGCCCAAAATCACCCTGCCAACCACGGGCTAAATGTACGCTTTGAACATGGCTCGATTGA
TGCGTTGCCCTTTCCTGATGGCTATTTCGATAGCTGTCGAGCCGATCGGGTTTTTCAACATTTGGAAGATCGCAAGCAGG
CCTTAGCCGAAATGCTGCGGGTAACCAAAGTTGGCGGCAGCATTGTGGTCAGTGACACCGATTGGGAAAGCCTTTTAATT
GATGGCCCTGATAAAACGCTGCTACGCCAGGTTGTGCAACGGATTACGGATCGGGTGCGCAATGGCTGGTCGGGCCGTCA
ACTGCCGCGTTTATTCCAGCTTTCGGGGTTGCAACAGGTGCAAACAACCGCGATGACAATTATTGAAACCAATCCAACCC
TTGCTGATCAACTGTTCGGTATCCAATCGGCGATTAATGATCTGCTGCAACAGGCCCAAATAACCCGCGAGGCAGCGCTC
GACTGGCAGCGCTATTGCCAAACTGCCAGTCGCTTGGGCGTTTTCTTCAGTGCAATTACTGGATTTGGGGTTGTTGGGAT
AAAGGGTTAA

Upstream 100 bases:

>100_bases
TACTTGAACCATGGCAACGTGGCGAATATCTGCCAATGCGCTTGCCACAGCCCGCTGAAACCCAAACGACGCTGAGGCTT
CAGCCAGAATAGGAACCAGC

Downstream 100 bases:

>100_bases
CCTCTGATAGCGTAGCTGAATCGAACGATTGAAGGATTGACCTATGTGGCAGGTGGTTATACAGGGTTAACTTTTGATAG
CGTAGCTGAATCGAACAGTT

Product: hypothetical protein

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTTTDWGAIDQTSAAPTHCIGYLNTVSELDQVAQYKAMTFELLDLQLGQRVLDVGCGAGNDARSIAQRVGAEGLVIGLDN
SEAMLTSAQNHPANHGLNVRFEHGSIDALPFPDGYFDSCRADRVFQHLEDRKQALAEMLRVTKVGGSIVVSDTDWESLLI
DGPDKTLLRQVVQRITDRVRNGWSGRQLPRLFQLSGLQQVQTTAMTIIETNPTLADQLFGIQSAINDLLQQAQITREAAL
DWQRYCQTASRLGVFFSAITGFGVVGIKG

Sequences:

>Translated_269_residues
MTTTDWGAIDQTSAAPTHCIGYLNTVSELDQVAQYKAMTFELLDLQLGQRVLDVGCGAGNDARSIAQRVGAEGLVIGLDN
SEAMLTSAQNHPANHGLNVRFEHGSIDALPFPDGYFDSCRADRVFQHLEDRKQALAEMLRVTKVGGSIVVSDTDWESLLI
DGPDKTLLRQVVQRITDRVRNGWSGRQLPRLFQLSGLQQVQTTAMTIIETNPTLADQLFGIQSAINDLLQQAQITREAAL
DWQRYCQTASRLGVFFSAITGFGVVGIKG
>Mature_268_residues
TTTDWGAIDQTSAAPTHCIGYLNTVSELDQVAQYKAMTFELLDLQLGQRVLDVGCGAGNDARSIAQRVGAEGLVIGLDNS
EAMLTSAQNHPANHGLNVRFEHGSIDALPFPDGYFDSCRADRVFQHLEDRKQALAEMLRVTKVGGSIVVSDTDWESLLID
GPDKTLLRQVVQRITDRVRNGWSGRQLPRLFQLSGLQQVQTTAMTIIETNPTLADQLFGIQSAINDLLQQAQITREAALD
WQRYCQTASRLGVFFSAITGFGVVGIKG

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=118, Percent_Identity=33.0508474576271, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29451; Mature: 29319

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTDWGAIDQTSAAPTHCIGYLNTVSELDQVAQYKAMTFELLDLQLGQRVLDVGCGAGN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DARSIAQRVGAEGLVIGLDNSEAMLTSAQNHPANHGLNVRFEHGSIDALPFPDGYFDSCR
HHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHH
ADRVFQHLEDRKQALAEMLRVTKVGGSIVVSDTDWESLLIDGPDKTLLRQVVQRITDRVR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHH
NGWSGRQLPRLFQLSGLQQVQTTAMTIIETNPTLADQLFGIQSAINDLLQQAQITREAAL
CCCCCCCHHHHHHHHCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DWQRYCQTASRLGVFFSAITGFGVVGIKG
HHHHHHHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure 
TTTDWGAIDQTSAAPTHCIGYLNTVSELDQVAQYKAMTFELLDLQLGQRVLDVGCGAGN
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DARSIAQRVGAEGLVIGLDNSEAMLTSAQNHPANHGLNVRFEHGSIDALPFPDGYFDSCR
HHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHH
ADRVFQHLEDRKQALAEMLRVTKVGGSIVVSDTDWESLLIDGPDKTLLRQVVQRITDRVR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHH
NGWSGRQLPRLFQLSGLQQVQTTAMTIIETNPTLADQLFGIQSAINDLLQQAQITREAAL
CCCCCCCHHHHHHHHCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DWQRYCQTASRLGVFFSAITGFGVVGIKG
HHHHHHHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]