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The map label for this gene is fabF [H]

Identifier: 159898111

GI number: 159898111

Start: 1841487

End: 1842728

Strand: Direct

Name: fabF [H]

Synonym: Haur_1587

Alternate gene names: 159898111

Gene position: 1841487-1842728 (Clockwise)

Preceding gene: 159898110

Following gene: 159898112

Centisome position: 29.02

GC content: 51.93

Gene sequence:

>1242_bases
ATGAATCGACGTGTCGTCGTCACAGGATTGGGCGCGATTAGCCCATTGGGCCTCGACGTGCCATCTTTGTGGGAGGGCAT
TGTCCAAGCACGTTCGGCGGTTGGACGAATTACCCAATTCGATCCAACGAAGTTTAGTGCTCAGATTGCCGCAGAAGTCC
ATGGCTTTGATGCTGCCAACTATATGGATAAAAAAGAGGCACGGCGCAACTCGCGGTTTGTGCATTTTGCGGTAGCAGCA
GCCAAAGAAGCCTTACGCAGCGCCGATTTTACGATTACCGACGAAAATGCTGATGATGTAGGGGTCATTATTGGCTGTGG
CGTTGGTGGTCTCGATAATTTTACAACCTATCTGCGGGTGATGGATGCCAAGGGTCCTGACCGAATCACACCATTTTTGA
TTCCAATGATGATTGTGGATATGGCAGGCGGGGTTGTGGCGATTGAAATTGGCGCACGCGGCCCGAATTTTTGTCCAGTT
TCAGCCTGTGCAACTTCGGGCAATGCTATCGGCGAAGCTTGGCATGTGATTCGACGTGGCGAGGCCAAAGTTATTTTAGC
GGGTGGTACAGAAGCATCAATTACCGAAATTGGGATTGGTGCCTTTGCGAGTGCCCGAGCGCTCTCGACCCGCAACGATG
ACCCAGCCACCGCCTCACGTCCCTTCGATAAAGATCGTGATGGCTTTGTGATGGGCGAAGGTTCAGGGGTTTTAGTGCTT
GAAGACTATGAGCATGCGGTCAGCCGTGGCGCAACCATTTTGGCTGAATTGGTTGGCTATGGAGTTAGCACCGATGCCTA
TCACATTACCATGCCTGCCGAAGATGGTTCGGGCGCGGTCAAGGCTATGCGTATGGCCTTGCGCCAAGCAGGCTTAGAGC
CACACGAATTGGGCTATTTGAATGCCCATGGCACTTCAACGCCAGTCAATGATCGAACTGAAACCTTGGCGGTTAAAAAA
GTGTTCGGCGATTACACTGCCAAATTGCCAATTAGTTCGAACAAATCGCAAATTGGCCATACCCTCGGGGCTGGCGGCGC
AATCGAAGCCGTGATCGGCATTTGCGCGATGCGCGAAGGCCTGCTCCCTGCCACGATCAACTATCATACTCCCGACCCTG
AGTGTGAGATCGATTGTGTGCCGAATACACCACGGCCAGCCCAATTCTCCAGCTTTATGAGCAATTCATTTGGCTTTGGT
GGCCATAACGTTAGTCTGTTGTTCAAGGCTTTTGAAGCCTAA

Upstream 100 bases:

>100_bases
CGCGAGAGGTCAACCAAATTTGCTGGTTGGCCTCTCGGTATGTTTAGGTAGTTGCTGCTATAATGGTGCGGCACTTTGCT
ATGCACTAGGAGGTTTTGCT

Downstream 100 bases:

>100_bases
AAAACCGCGCAAGCTAGGTAGATTCTTGGGATCTGCCTAGCTTGCTTAGCTTAACATTGCTGCTATGGATCTAAACAAAC
TACAAGCTGAACTTGGTTAC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNRRVVVTGLGAISPLGLDVPSLWEGIVQARSAVGRITQFDPTKFSAQIAAEVHGFDAANYMDKKEARRNSRFVHFAVAA
AKEALRSADFTITDENADDVGVIIGCGVGGLDNFTTYLRVMDAKGPDRITPFLIPMMIVDMAGGVVAIEIGARGPNFCPV
SACATSGNAIGEAWHVIRRGEAKVILAGGTEASITEIGIGAFASARALSTRNDDPATASRPFDKDRDGFVMGEGSGVLVL
EDYEHAVSRGATILAELVGYGVSTDAYHITMPAEDGSGAVKAMRMALRQAGLEPHELGYLNAHGTSTPVNDRTETLAVKK
VFGDYTAKLPISSNKSQIGHTLGAGGAIEAVIGICAMREGLLPATINYHTPDPECEIDCVPNTPRPAQFSSFMSNSFGFG
GHNVSLLFKAFEA

Sequences:

>Translated_413_residues
MNRRVVVTGLGAISPLGLDVPSLWEGIVQARSAVGRITQFDPTKFSAQIAAEVHGFDAANYMDKKEARRNSRFVHFAVAA
AKEALRSADFTITDENADDVGVIIGCGVGGLDNFTTYLRVMDAKGPDRITPFLIPMMIVDMAGGVVAIEIGARGPNFCPV
SACATSGNAIGEAWHVIRRGEAKVILAGGTEASITEIGIGAFASARALSTRNDDPATASRPFDKDRDGFVMGEGSGVLVL
EDYEHAVSRGATILAELVGYGVSTDAYHITMPAEDGSGAVKAMRMALRQAGLEPHELGYLNAHGTSTPVNDRTETLAVKK
VFGDYTAKLPISSNKSQIGHTLGAGGAIEAVIGICAMREGLLPATINYHTPDPECEIDCVPNTPRPAQFSSFMSNSFGFG
GHNVSLLFKAFEA
>Mature_413_residues
MNRRVVVTGLGAISPLGLDVPSLWEGIVQARSAVGRITQFDPTKFSAQIAAEVHGFDAANYMDKKEARRNSRFVHFAVAA
AKEALRSADFTITDENADDVGVIIGCGVGGLDNFTTYLRVMDAKGPDRITPFLIPMMIVDMAGGVVAIEIGARGPNFCPV
SACATSGNAIGEAWHVIRRGEAKVILAGGTEASITEIGIGAFASARALSTRNDDPATASRPFDKDRDGFVMGEGSGVLVL
EDYEHAVSRGATILAELVGYGVSTDAYHITMPAEDGSGAVKAMRMALRQAGLEPHELGYLNAHGTSTPVNDRTETLAVKK
VFGDYTAKLPISSNKSQIGHTLGAGGAIEAVIGICAMREGLLPATINYHTPDPECEIDCVPNTPRPAQFSSFMSNSFGFG
GHNVSLLFKAFEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=39.3285371702638, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI223972627, Length=174, Percent_Identity=40.2298850574713, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI41872631, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=46.0048426150121, Blast_Score=348, Evalue=3e-97,
Organism=Escherichia coli, GI1788663, Length=415, Percent_Identity=33.2530120481928, Blast_Score=207, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71983541, Length=414, Percent_Identity=37.6811594202899, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=256, Percent_Identity=43.75, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI212642053, Length=364, Percent_Identity=26.3736263736264, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=259, Percent_Identity=27.7992277992278, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=36.9127516778523, Blast_Score=272, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24644341, Length=417, Percent_Identity=41.9664268585132, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI19920632, Length=402, Percent_Identity=25.6218905472637, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI221330659, Length=402, Percent_Identity=25.6218905472637, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581345, Length=404, Percent_Identity=24.2574257425743, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43566; Mature: 43566

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRVVVTGLGAISPLGLDVPSLWEGIVQARSAVGRITQFDPTKFSAQIAAEVHGFDAAN
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHH
YMDKKEARRNSRFVHFAVAAAKEALRSADFTITDENADDVGVIIGCGVGGLDNFTTYLRV
HHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHEEEHEE
MDAKGPDRITPFLIPMMIVDMAGGVVAIEIGARGPNFCPVSACATSGNAIGEAWHVIRRG
ECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCC
EAKVILAGGTEASITEIGIGAFASARALSTRNDDPATASRPFDKDRDGFVMGEGSGVLVL
CEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EDYEHAVSRGATILAELVGYGVSTDAYHITMPAEDGSGAVKAMRMALRQAGLEPHELGYL
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHCEEE
NAHGTSTPVNDRTETLAVKKVFGDYTAKLPISSNKSQIGHTLGAGGAIEAVIGICAMREG
ECCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHCHHHCCCHHHHHHHHHHHHHCC
LLPATINYHTPDPECEIDCVPNTPRPAQFSSFMSNSFGFGGHNVSLLFKAFEA
CCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEHEEECCC
>Mature Secondary Structure
MNRRVVVTGLGAISPLGLDVPSLWEGIVQARSAVGRITQFDPTKFSAQIAAEVHGFDAAN
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHH
YMDKKEARRNSRFVHFAVAAAKEALRSADFTITDENADDVGVIIGCGVGGLDNFTTYLRV
HHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEECCCCCCEEEEEECCCCCHHHHEEEHEE
MDAKGPDRITPFLIPMMIVDMAGGVVAIEIGARGPNFCPVSACATSGNAIGEAWHVIRRG
ECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCC
EAKVILAGGTEASITEIGIGAFASARALSTRNDDPATASRPFDKDRDGFVMGEGSGVLVL
CEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
EDYEHAVSRGATILAELVGYGVSTDAYHITMPAEDGSGAVKAMRMALRQAGLEPHELGYL
CCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHCEEE
NAHGTSTPVNDRTETLAVKKVFGDYTAKLPISSNKSQIGHTLGAGGAIEAVIGICAMREG
ECCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCHHHHCHHHCCCHHHHHHHHHHHHHCC
LLPATINYHTPDPECEIDCVPNTPRPAQFSSFMSNSFGFGGHNVSLLFKAFEA
CCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]