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The map label for this gene is flp [H]

Identifier: 159898039

GI number: 159898039

Start: 1764576

End: 1766438

Strand: Direct

Name: flp [H]

Synonym: Haur_1514

Alternate gene names: 159898039

Gene position: 1764576-1766438 (Clockwise)

Preceding gene: 159898038

Following gene: 159898040

Centisome position: 27.8

GC content: 48.9

Gene sequence:

>1863_bases
GTGCCGATTCCCACTAATTGGCAACTTGAGGAACAAGCTGGTATTGTGCGGCTGAACGATCCCGATCAAAAAATTACGAT
TGCCCTGCTGAGTGTTGAAGAAGCCGATTTGGCCAAGGCGATTGAATTAGGCTGGCAGCAAGCCGACCCAAGTTTTACGC
TTACCCCCGATGATAGCCAAGAAATGCCAGCGCCAAATGGTGTGGAAAAAGCCTTAGTTGCGGCATATGACACCAAGAAC
ACGGCTCAAACGACGATTGCCTTGGCCCAATTACATGAAGGCATGGCGTATTTGATGCTGGTGCAAGGCGAAAATACCAC
AATTGCCAAGCGTCAATCGCAAGTTGGCATTATTCAATCGGGCTTTACGATTTTGGCGCTCAATCAAACCACGCTTAGCG
CTGATCAACGGGTCGATGTTGGGCCAGAACTGATCAGCGAATTAGAAAGCTTTATCCAAGCCGAACAAGCCGAATATAAA
ATTCCTGGCGTGAGTGTGGCGATTGTCCAAGATGGTCAAATTGTCTATAGCAAGGGTTTTGGCGTGCGTGATGTTGTTTC
GCAAGCCCCCATGGATGCTGATACCCAGATGATGATTGGCTCAACTGGCAAGAGCTTAACGACCTTATTAATGGCAACTT
TGGTCGATCAAGGCAAGCTGGATTGGGATACCCCGGTTGTCGAGTTATTGCCCAATTTCAAGGTCAAAGATCCGGAAATT
ACCAAGCAAATCACGGTGCGCCATTTGGTTTGTGCCTGTACTGGCGTGCCACGCCGTGATTATGAGATGATTTTCAATGC
TGAGGATTTGGATGCCCAAGGCATTATCGCTTCGGTTGCTGATTTTGAGTTCTTTACCGATTTTGGCGAAGCTTTTCAAT
ATAGCAATCAGATGGTGGCGATTGGCGGCTTTGCGGCAGCGGCGGCCAGTGGCGGCGAGCTAACGCAGCTTGATCAAACC
TTTGCTCAAGCATTAACCGAACGGGTGCTCAAACCAATGGGTATGAACAGCACCACGCTTGATCAAGCAGCCGTTGAGGC
CAGCCCTAACCATGCGCTGCCCCATGGCTTGGATTTGGTCAACGCAACCTACCAAACCTTGCCAATCAGCATGGAATTTG
CGATCAAAGGAGTAGCTCCAGCAGGCGCAACCGAGTGGTCAACTGCCAACGATATGGGCAATTATCTGATTACCCTGCTC
AATCATGGCATTACGCCTAGTGGTCAACGCTTAGTTTCCGACGAAAATTTAGCTGTGTTGTGGGAGCCGCAAATTGCCAT
CGATGCTAAATCGAGCTATGGGCTTGGTTGGATGATCAGCGACTACCATGGCTTGGAATTTATTGCTCACGGCGGTACGA
CCTTTGGTTTCTCATCAGAGTTTGCCTTTATTCCAGAGGCCAACATTGGGATTGTGGTGTTGACTAATGGCCAATACGCC
AACCATATTGCTACAAGTATTAGCGACCGCTACTTTGAATTAGCCTTTGATCAGCCAAGCAAGGCTGCTGAAACCTCAGC
CTACACTGCTCAAAGCATCGAACAATCGTTGGGCGAAATCGCCAAAAATATCGTGCCTGAGCTGGATTTGGCGAGCGTTG
AGCCATTGTTGGGCAGCTATACCAATGCCGCCTTGGGTGATGTGAGTTTGCTACTCAGTGGCGAGGAATTGTGGCTGGAT
ATTGGTGCAATTCAGACCCAATTCAAGCCAGTCTTGAACGAACAAGGCCAGCCAGATGGCTATCTCTCAGTAACGCCACC
GTTTACTGGAATTCCCTTCAAAACCGGAGTTGATGCCAATAACCAACCAACCTTGACCATGGATCTTGGCAGCGAAACCT
ATCTCTTTACCCGTAAACCATAA

Upstream 100 bases:

>100_bases
CGAACCAACTGCTGCCACCACTGTCACCGCAGCGCCAACTAAGGCCAGCGCAGGTGTCGAAAGCAGTAGTATCTATACCA
GCACGAGTCAATTATTCTCA

Downstream 100 bases:

>100_bases
ACTAAGCCACAACCGCCCAGCTAGTAGCAGAAGCCTAGCTGGGCGATAATTGAGCTTCAGTGACCAAAATACCCTAAAAG
AATTATTTACGCTTGTTTAC

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MPIPTNWQLEEQAGIVRLNDPDQKITIALLSVEEADLAKAIELGWQQADPSFTLTPDDSQEMPAPNGVEKALVAAYDTKN
TAQTTIALAQLHEGMAYLMLVQGENTTIAKRQSQVGIIQSGFTILALNQTTLSADQRVDVGPELISELESFIQAEQAEYK
IPGVSVAIVQDGQIVYSKGFGVRDVVSQAPMDADTQMMIGSTGKSLTTLLMATLVDQGKLDWDTPVVELLPNFKVKDPEI
TKQITVRHLVCACTGVPRRDYEMIFNAEDLDAQGIIASVADFEFFTDFGEAFQYSNQMVAIGGFAAAAASGGELTQLDQT
FAQALTERVLKPMGMNSTTLDQAAVEASPNHALPHGLDLVNATYQTLPISMEFAIKGVAPAGATEWSTANDMGNYLITLL
NHGITPSGQRLVSDENLAVLWEPQIAIDAKSSYGLGWMISDYHGLEFIAHGGTTFGFSSEFAFIPEANIGIVVLTNGQYA
NHIATSISDRYFELAFDQPSKAAETSAYTAQSIEQSLGEIAKNIVPELDLASVEPLLGSYTNAALGDVSLLLSGEELWLD
IGAIQTQFKPVLNEQGQPDGYLSVTPPFTGIPFKTGVDANNQPTLTMDLGSETYLFTRKP

Sequences:

>Translated_620_residues
MPIPTNWQLEEQAGIVRLNDPDQKITIALLSVEEADLAKAIELGWQQADPSFTLTPDDSQEMPAPNGVEKALVAAYDTKN
TAQTTIALAQLHEGMAYLMLVQGENTTIAKRQSQVGIIQSGFTILALNQTTLSADQRVDVGPELISELESFIQAEQAEYK
IPGVSVAIVQDGQIVYSKGFGVRDVVSQAPMDADTQMMIGSTGKSLTTLLMATLVDQGKLDWDTPVVELLPNFKVKDPEI
TKQITVRHLVCACTGVPRRDYEMIFNAEDLDAQGIIASVADFEFFTDFGEAFQYSNQMVAIGGFAAAAASGGELTQLDQT
FAQALTERVLKPMGMNSTTLDQAAVEASPNHALPHGLDLVNATYQTLPISMEFAIKGVAPAGATEWSTANDMGNYLITLL
NHGITPSGQRLVSDENLAVLWEPQIAIDAKSSYGLGWMISDYHGLEFIAHGGTTFGFSSEFAFIPEANIGIVVLTNGQYA
NHIATSISDRYFELAFDQPSKAAETSAYTAQSIEQSLGEIAKNIVPELDLASVEPLLGSYTNAALGDVSLLLSGEELWLD
IGAIQTQFKPVLNEQGQPDGYLSVTPPFTGIPFKTGVDANNQPTLTMDLGSETYLFTRKP
>Mature_619_residues
PIPTNWQLEEQAGIVRLNDPDQKITIALLSVEEADLAKAIELGWQQADPSFTLTPDDSQEMPAPNGVEKALVAAYDTKNT
AQTTIALAQLHEGMAYLMLVQGENTTIAKRQSQVGIIQSGFTILALNQTTLSADQRVDVGPELISELESFIQAEQAEYKI
PGVSVAIVQDGQIVYSKGFGVRDVVSQAPMDADTQMMIGSTGKSLTTLLMATLVDQGKLDWDTPVVELLPNFKVKDPEIT
KQITVRHLVCACTGVPRRDYEMIFNAEDLDAQGIIASVADFEFFTDFGEAFQYSNQMVAIGGFAAAAASGGELTQLDQTF
AQALTERVLKPMGMNSTTLDQAAVEASPNHALPHGLDLVNATYQTLPISMEFAIKGVAPAGATEWSTANDMGNYLITLLN
HGITPSGQRLVSDENLAVLWEPQIAIDAKSSYGLGWMISDYHGLEFIAHGGTTFGFSSEFAFIPEANIGIVVLTNGQYAN
HIATSISDRYFELAFDQPSKAAETSAYTAQSIEQSLGEIAKNIVPELDLASVEPLLGSYTNAALGDVSLLLSGEELWLDI
GAIQTQFKPVLNEQGQPDGYLSVTPPFTGIPFKTGVDANNQPTLTMDLGSETYLFTRKP

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI26051233, Length=102, Percent_Identity=40.1960784313725, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI26051231, Length=102, Percent_Identity=40.1960784313725, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 66851; Mature: 66720

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIPTNWQLEEQAGIVRLNDPDQKITIALLSVEEADLAKAIELGWQQADPSFTLTPDDSQ
CCCCCCCEEHHCCCEEEECCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCC
EMPAPNGVEKALVAAYDTKNTAQTTIALAQLHEGMAYLMLVQGENTTIAKRQSQVGIIQS
CCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHCCEEEEEEEECCCCEEEHHHCCCEEEEC
GFTILALNQTTLSADQRVDVGPELISELESFIQAEQAEYKIPGVSVAIVQDGQIVYSKGF
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEEEECCEEEEECCC
GVRDVVSQAPMDADTQMMIGSTGKSLTTLLMATLVDQGKLDWDTPVVELLPNFKVKDPEI
CHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHH
TKQITVRHLVCACTGVPRRDYEMIFNAEDLDAQGIIASVADFEFFTDFGEAFQYSNQMVA
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
IGGFAAAAASGGELTQLDQTFAQALTERVLKPMGMNSTTLDQAAVEASPNHALPHGLDLV
EECHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCHHH
NATYQTLPISMEFAIKGVAPAGATEWSTANDMGNYLITLLNHGITPSGQRLVSDENLAVL
HCHHHHCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEE
WEPQIAIDAKSSYGLGWMISDYHGLEFIAHGGTTFGFSSEFAFIPEANIGIVVLTNGQYA
ECCCEEEECCCCCCEEEEEECCCCEEEEECCCCEECCCCCEEECCCCCEEEEEEECCCHH
NHIATSISDRYFELAFDQPSKAAETSAYTAQSIEQSLGEIAKNIVPELDLASVEPLLGSY
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
TNAALGDVSLLLSGEELWLDIGAIQTQFKPVLNEQGQPDGYLSVTPPFTGIPFKTGVDAN
CCCHHCCEEEEEECCHHEEEHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCC
NQPTLTMDLGSETYLFTRKP
CCCEEEEECCCCEEEEEECC
>Mature Secondary Structure 
PIPTNWQLEEQAGIVRLNDPDQKITIALLSVEEADLAKAIELGWQQADPSFTLTPDDSQ
CCCCCCEEHHCCCEEEECCCCCEEEEEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCC
EMPAPNGVEKALVAAYDTKNTAQTTIALAQLHEGMAYLMLVQGENTTIAKRQSQVGIIQS
CCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHCCEEEEEEEECCCCEEEHHHCCCEEEEC
GFTILALNQTTLSADQRVDVGPELISELESFIQAEQAEYKIPGVSVAIVQDGQIVYSKGF
CCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEEEECCEEEEECCC
GVRDVVSQAPMDADTQMMIGSTGKSLTTLLMATLVDQGKLDWDTPVVELLPNFKVKDPEI
CHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHH
TKQITVRHLVCACTGVPRRDYEMIFNAEDLDAQGIIASVADFEFFTDFGEAFQYSNQMVA
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEE
IGGFAAAAASGGELTQLDQTFAQALTERVLKPMGMNSTTLDQAAVEASPNHALPHGLDLV
EECHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCHHH
NATYQTLPISMEFAIKGVAPAGATEWSTANDMGNYLITLLNHGITPSGQRLVSDENLAVL
HCHHHHCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEE
WEPQIAIDAKSSYGLGWMISDYHGLEFIAHGGTTFGFSSEFAFIPEANIGIVVLTNGQYA
ECCCEEEECCCCCCEEEEEECCCCEEEEECCCCEECCCCCEEECCCCCEEEEEEECCCHH
NHIATSISDRYFELAFDQPSKAAETSAYTAQSIEQSLGEIAKNIVPELDLASVEPLLGSY
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
TNAALGDVSLLLSGEELWLDIGAIQTQFKPVLNEQGQPDGYLSVTPPFTGIPFKTGVDAN
CCCHHCCEEEEEECCHHEEEHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCC
NQPTLTMDLGSETYLFTRKP
CCCEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA