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The map label for this gene is yhcY [H]

Identifier: 159897837

GI number: 159897837

Start: 1518697

End: 1519842

Strand: Direct

Name: yhcY [H]

Synonym: Haur_1308

Alternate gene names: 159897837

Gene position: 1518697-1519842 (Clockwise)

Preceding gene: 159897835

Following gene: 159897838

Centisome position: 23.93

GC content: 52.09

Gene sequence:

>1146_bases
ATGAGCAATGATCCAGCGGTTTTGGCTCGCCGAAACCATGAATTGATGATTTTGAACCAAATTGCCGAGGCGTTGAATCG
GAGCACGCAGCTTGATCAGGCGTTACAAACTGTTTTAGAACTAGTGGCTGAGTTGTTGGGGTTGCACACAGGTTGGGTTT
GGCTGTTACGTGAGGATCAAACGACCCATTATTTGGCCGCCGCCTATCATCTGCCGCCTGTGTTGTGCCACCCCCAAGCC
TTAGAAGACGATTGTTATTGCCTGGAACGTTTTCGCGATGATGATTTGGAACGGGCTGCCAACATTAGCGTGATTCGTTG
CACACGTTTGCGCCACGTTCCGCAAGGTACCGAGGTGCGTTTTCATTCGTCAATTCCGTTGATGGCCCATGGCCGCAAGC
TTGGAGTGTTTAATGTGGCTAGCCCTGATTGGTGTGAATTGAGCGCTGATGATTTGCGTTTATTGCACACGGTCGGCGAT
TTGCTGAGCATGGCGATTGAACGTACACGCCTATTTGAACGCTCGCTCAGCTTGGGTGCGGTCGAGGAGCGTAACCGGAT
TGCCCGCGAAATTCACGATACTTTGGCCCAAGGCTTGACTGCGGTATTGCTACAACTTGAAACCGCCGATGCTTTATTTG
AAACGGGTGCTACCGAGCGTGGCCGAGCCAAAATTCAGCAAGCGCTACAATGGACGCGCTATAATCTTGATGAGGCGCGG
CGTTCGGTACTCGATCTGCGGGCGGCTCCGCTCGAAGGCCGTAGTTTGGTTGAAGCCTTGGCAACCTTGAAGCATGAGCA
TGACCCATTCAGCTTTGACATTCAAACGATTGGCGCGTTGCAGCCGTTGCCCTTACGGATCGAAGTTGGCTTGTTGCGAA
TTGTGCAAGAAGCCTTGAATAATGTGCGGCAGCATGCCCAAGCCAACGCTGTGGTGATTGAATATCACGCTACGCCGACC
CAGATTGAAATTTGCGTGCATGACGATGGCTGTGGCTTTGACCCAACCTTGCCCAAGCCCCAACATTTTGGCCTGATTGG
CATGAATGAGCGTACTCGGTTGCTGAGCGGCAGCCTTGAAATCAAAAGTACCCTTGGCGCAGGGACTGAGGTTTGTATTG
TTGTGCCACTGGGGAGTTCCAAATGA

Upstream 100 bases:

>100_bases
TAAACTCGCACTAAAATGGTTGTTAGAGTAGAGCCACAACGGTGGCAAATTTGGCATGGATATTTAGGCATTTGGCGAAA
TTGCCAAAAAGGTGTTGATA

Downstream 100 bases:

>100_bases
TCCGCATTTTGGTGGTTGATGATCATCCGGTGGTGCGCGAGGGCTTGGTGGCAATTCTCAGCACCCAAGCCGATTTTTCC
GTGGTTGGTGAGGCTAGCGC

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSNDPAVLARRNHELMILNQIAEALNRSTQLDQALQTVLELVAELLGLHTGWVWLLREDQTTHYLAAAYHLPPVLCHPQA
LEDDCYCLERFRDDDLERAANISVIRCTRLRHVPQGTEVRFHSSIPLMAHGRKLGVFNVASPDWCELSADDLRLLHTVGD
LLSMAIERTRLFERSLSLGAVEERNRIAREIHDTLAQGLTAVLLQLETADALFETGATERGRAKIQQALQWTRYNLDEAR
RSVLDLRAAPLEGRSLVEALATLKHEHDPFSFDIQTIGALQPLPLRIEVGLLRIVQEALNNVRQHAQANAVVIEYHATPT
QIEICVHDDGCGFDPTLPKPQHFGLIGMNERTRLLSGSLEIKSTLGAGTEVCIVVPLGSSK

Sequences:

>Translated_381_residues
MSNDPAVLARRNHELMILNQIAEALNRSTQLDQALQTVLELVAELLGLHTGWVWLLREDQTTHYLAAAYHLPPVLCHPQA
LEDDCYCLERFRDDDLERAANISVIRCTRLRHVPQGTEVRFHSSIPLMAHGRKLGVFNVASPDWCELSADDLRLLHTVGD
LLSMAIERTRLFERSLSLGAVEERNRIAREIHDTLAQGLTAVLLQLETADALFETGATERGRAKIQQALQWTRYNLDEAR
RSVLDLRAAPLEGRSLVEALATLKHEHDPFSFDIQTIGALQPLPLRIEVGLLRIVQEALNNVRQHAQANAVVIEYHATPT
QIEICVHDDGCGFDPTLPKPQHFGLIGMNERTRLLSGSLEIKSTLGAGTEVCIVVPLGSSK
>Mature_380_residues
SNDPAVLARRNHELMILNQIAEALNRSTQLDQALQTVLELVAELLGLHTGWVWLLREDQTTHYLAAAYHLPPVLCHPQAL
EDDCYCLERFRDDDLERAANISVIRCTRLRHVPQGTEVRFHSSIPLMAHGRKLGVFNVASPDWCELSADDLRLLHTVGDL
LSMAIERTRLFERSLSLGAVEERNRIAREIHDTLAQGLTAVLLQLETADALFETGATERGRAKIQQALQWTRYNLDEARR
SVLDLRAAPLEGRSLVEALATLKHEHDPFSFDIQTIGALQPLPLRIEVGLLRIVQEALNNVRQHAQANAVVIEYHATPTQ
IEICVHDDGCGFDPTLPKPQHFGLIGMNERTRLLSGSLEIKSTLGAGTEVCIVVPLGSSK

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=248, Percent_Identity=28.6290322580645, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082311, Length=250, Percent_Identity=28.8, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788812, Length=228, Percent_Identity=31.140350877193, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42522; Mature: 42391

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDPAVLARRNHELMILNQIAEALNRSTQLDQALQTVLELVAELLGLHTGWVWLLREDQ
CCCCCCEEEECCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TTHYLAAAYHLPPVLCHPQALEDDCYCLERFRDDDLERAANISVIRCTRLRHVPQGTEVR
CCEEEEEHHCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHCCEEEEEEHHHCCCCCCCEE
FHSSIPLMAHGRKLGVFNVASPDWCELSADDLRLLHTVGDLLSMAIERTRLFERSLSLGA
EECCCCCEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VEERNRIAREIHDTLAQGLTAVLLQLETADALFETGATERGRAKIQQALQWTRYNLDEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHH
RSVLDLRAAPLEGRSLVEALATLKHEHDPFSFDIQTIGALQPLPLRIEVGLLRIVQEALN
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCEEEHHHHHHHHHHHHH
NVRQHAQANAVVIEYHATPTQIEICVHDDGCGFDPTLPKPQHFGLIGMNERTRLLSGSLE
HHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHCCCEE
IKSTLGAGTEVCIVVPLGSSK
EHHHCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
SNDPAVLARRNHELMILNQIAEALNRSTQLDQALQTVLELVAELLGLHTGWVWLLREDQ
CCCCCEEEECCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TTHYLAAAYHLPPVLCHPQALEDDCYCLERFRDDDLERAANISVIRCTRLRHVPQGTEVR
CCEEEEEHHCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHCCEEEEEEHHHCCCCCCCEE
FHSSIPLMAHGRKLGVFNVASPDWCELSADDLRLLHTVGDLLSMAIERTRLFERSLSLGA
EECCCCCEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VEERNRIAREIHDTLAQGLTAVLLQLETADALFETGATERGRAKIQQALQWTRYNLDEAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHH
RSVLDLRAAPLEGRSLVEALATLKHEHDPFSFDIQTIGALQPLPLRIEVGLLRIVQEALN
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCEEEHHHHHHHHHHHHH
NVRQHAQANAVVIEYHATPTQIEICVHDDGCGFDPTLPKPQHFGLIGMNERTRLLSGSLE
HHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHCCCEE
IKSTLGAGTEVCIVVPLGSSK
EHHHCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]