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The map label for this gene is ribBA [H]

Identifier: 159897835

GI number: 159897835

Start: 1516664

End: 1517893

Strand: Direct

Name: ribBA [H]

Synonym: Haur_1306

Alternate gene names: 159897835

Gene position: 1516664-1517893 (Clockwise)

Preceding gene: 159897834

Following gene: 159897837

Centisome position: 23.9

GC content: 50.41

Gene sequence:

>1230_bases
ATGCCGTTGGCAAGCATCGAAGAAGCACTGCAAGATTATGCAGCCGGAAAAATGGTGATCATCGTAGACGATGAAGATCG
CGAAAACGAGGGTGATCTCGCGTGTGCTGCCCAGTTTGTTACGCCACAGGCAATTAATTTTATGGCCAAAGAAGGCCGTG
GGCTGATCTGTTTAGCCATTACTGGTCAGCGCCTCGACGAGTTGGAAATTCCAATGATGGTGACCTCGAATAACTCTAAG
TTTGGCACCAATTTCACGGTGTCGATCGAGGCTGCTCAAGGCGTAACCACCGGAATTTCAGCCTATGATCGAGCGCATAC
CATCCAAACCGTGATCAATCCAAACTCCAAGCCCAGCGATATTTCGCGGCCTGGCCATGTGTTTCCTTTACGCGCTGCCG
AGGGTGGCGTATTGCGGCGGGTTGGCCAAACTGAAGCCTCAGTCGATATGTCACGCTTGGCGGGTTTGTATCCTGCTGGC
GTAATTTGCGAAATTATGAACGACGATGGCACGATGGCTCGGATGCCTGACCTTGAGATTTTCGCCGAAAAGCATGATCT
CAAAATTATCAGCGTTGAGCAATTAATTCGCTTTCGTCGTGAGCGTGAATTTCTAGTTACGCGCACTGCTGAAGCTCGCT
TACCAACGGCCTATGGCGAATTTCAAATCGTCTCATATGAGAGCAAAATCAACACACCTGATCTGCAAGCCAAGGAGGCA
GTGGCCTTGATTATGGGCGATATTTCAACCGACGAGCCAGTGCTGGTGCGGGTGCACTCCGAATGTTTAACTGGCGATGC
CTTTGGCTCATTGCGTTGTGATTGCGGCCCACAGCTTGAAAAAGCGATGCAACGGATTGCCCAAGAAGGCCGTGGCGTGT
TGCTGTATTTGCGCCAAGAAGGCCGTGGAATTGGTCTGACCAACAAAATTCGCGCCTATATGCTGCAAGATCAGGGCTTG
GATACGGTTGAAGCTAACGAGCGCCTAGGTTTCCCTGCTGATTTACGCGATTATGGCTTGGGAGCGCAAATGCTGGCCGA
TTTGGGTCTGCGCGATTTACGCCTACTCACCAATAATCCCAAAAAGATCATTGGTTTTGAAGGCTATGGTTTGCATGTGG
TTGAACAATTGCCCTTGGAAACCGACCCTAACACTGAAAACCAAGCCTATCTGCGCACCAAGCGCGAACGCATGGGCCAT
ACGTTATCGAATTTGAATTCGGCGGAATAG

Upstream 100 bases:

>100_bases
GATTGTTTCGTGCTGACTGAACCAACCCCGATTAGTCATCGGTGGTTGTGGGTATGTACCAAACAATGAGCGTTCTCATT
GTCACAAAGGAGTGGAATGT

Downstream 100 bases:

>100_bases
CCTTATAACCATGCCAACCGCCGTTCGCGCATGCTGACCCAACGTGCTTGACCGATCACCAAATGGTCAAGCACGTCGAT
ATCGAGCAGTTGGCCAGCCT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: 3,4-dihydroxy-2-butanone 4-phosphate synthase; DHBP synthase; GTP cyclohydrolase-2; GTP cyclohydrolase II [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPLASIEEALQDYAAGKMVIIVDDEDRENEGDLACAAQFVTPQAINFMAKEGRGLICLAITGQRLDELEIPMMVTSNNSK
FGTNFTVSIEAAQGVTTGISAYDRAHTIQTVINPNSKPSDISRPGHVFPLRAAEGGVLRRVGQTEASVDMSRLAGLYPAG
VICEIMNDDGTMARMPDLEIFAEKHDLKIISVEQLIRFRREREFLVTRTAEARLPTAYGEFQIVSYESKINTPDLQAKEA
VALIMGDISTDEPVLVRVHSECLTGDAFGSLRCDCGPQLEKAMQRIAQEGRGVLLYLRQEGRGIGLTNKIRAYMLQDQGL
DTVEANERLGFPADLRDYGLGAQMLADLGLRDLRLLTNNPKKIIGFEGYGLHVVEQLPLETDPNTENQAYLRTKRERMGH
TLSNLNSAE

Sequences:

>Translated_409_residues
MPLASIEEALQDYAAGKMVIIVDDEDRENEGDLACAAQFVTPQAINFMAKEGRGLICLAITGQRLDELEIPMMVTSNNSK
FGTNFTVSIEAAQGVTTGISAYDRAHTIQTVINPNSKPSDISRPGHVFPLRAAEGGVLRRVGQTEASVDMSRLAGLYPAG
VICEIMNDDGTMARMPDLEIFAEKHDLKIISVEQLIRFRREREFLVTRTAEARLPTAYGEFQIVSYESKINTPDLQAKEA
VALIMGDISTDEPVLVRVHSECLTGDAFGSLRCDCGPQLEKAMQRIAQEGRGVLLYLRQEGRGIGLTNKIRAYMLQDQGL
DTVEANERLGFPADLRDYGLGAQMLADLGLRDLRLLTNNPKKIIGFEGYGLHVVEQLPLETDPNTENQAYLRTKRERMGH
TLSNLNSAE
>Mature_408_residues
PLASIEEALQDYAAGKMVIIVDDEDRENEGDLACAAQFVTPQAINFMAKEGRGLICLAITGQRLDELEIPMMVTSNNSKF
GTNFTVSIEAAQGVTTGISAYDRAHTIQTVINPNSKPSDISRPGHVFPLRAAEGGVLRRVGQTEASVDMSRLAGLYPAGV
ICEIMNDDGTMARMPDLEIFAEKHDLKIISVEQLIRFRREREFLVTRTAEARLPTAYGEFQIVSYESKINTPDLQAKEAV
ALIMGDISTDEPVLVRVHSECLTGDAFGSLRCDCGPQLEKAMQRIAQEGRGVLLYLRQEGRGIGLTNKIRAYMLQDQGLD
TVEANERLGFPADLRDYGLGAQMLADLGLRDLRLLTNNPKKIIGFEGYGLHVVEQLPLETDPNTENQAYLRTKRERMGHT
LSNLNSAE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1787533, Length=198, Percent_Identity=58.0808080808081, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1789420, Length=202, Percent_Identity=50.4950495049505, Blast_Score=221, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=41.1764705882353, Blast_Score=182, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6319438, Length=172, Percent_Identity=48.2558139534884, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12; =3.5.4.25 [H]

Molecular weight: Translated: 45104; Mature: 44973

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLASIEEALQDYAAGKMVIIVDDEDRENEGDLACAAQFVTPQAINFMAKEGRGLICLAI
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEE
TGQRLDELEIPMMVTSNNSKFGTNFTVSIEAAQGVTTGISAYDRAHTIQTVINPNSKPSD
CCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHEEEEEECCCCCCCC
ISRPGHVFPLRAAEGGVLRRVGQTEASVDMSRLAGLYPAGVICEIMNDDGTMARMPDLEI
CCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHE
FAEKHDLKIISVEQLIRFRREREFLVTRTAEARLPTAYGEFQIVSYESKINTPDLQAKEA
EECCCCEEEEEHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHE
VALIMGDISTDEPVLVRVHSECLTGDAFGSLRCDCGPQLEKAMQRIAQEGRGVLLYLRQE
EEEEEECCCCCCCEEEEEECHHHCCCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEEEEC
GRGIGLTNKIRAYMLQDQGLDTVEANERLGFPADLRDYGLGAQMLADLGLRDLRLLTNNP
CCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHCCHHEEHEEECCC
KKIIGFEGYGLHVVEQLPLETDPNTENQAYLRTKRERMGHTLSNLNSAE
CEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCC
>Mature Secondary Structure 
PLASIEEALQDYAAGKMVIIVDDEDRENEGDLACAAQFVTPQAINFMAKEGRGLICLAI
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEE
TGQRLDELEIPMMVTSNNSKFGTNFTVSIEAAQGVTTGISAYDRAHTIQTVINPNSKPSD
CCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHEEEEEECCCCCCCC
ISRPGHVFPLRAAEGGVLRRVGQTEASVDMSRLAGLYPAGVICEIMNDDGTMARMPDLEI
CCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHE
FAEKHDLKIISVEQLIRFRREREFLVTRTAEARLPTAYGEFQIVSYESKINTPDLQAKEA
EECCCCEEEEEHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHE
VALIMGDISTDEPVLVRVHSECLTGDAFGSLRCDCGPQLEKAMQRIAQEGRGVLLYLRQE
EEEEEECCCCCCCEEEEEECHHHCCCCCCCEECCCCHHHHHHHHHHHHCCCCEEEEEEEC
GRGIGLTNKIRAYMLQDQGLDTVEANERLGFPADLRDYGLGAQMLADLGLRDLRLLTNNP
CCCCCCHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHCCHHEEHEEECCC
KKIIGFEGYGLHVVEQLPLETDPNTENQAYLRTKRERMGHTLSNLNSAE
CEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA