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The map label for this gene is opuCB [H]

Identifier: 159896881

GI number: 159896881

Start: 420026

End: 420679

Strand: Direct

Name: opuCB [H]

Synonym: Haur_0349

Alternate gene names: 159896881

Gene position: 420026-420679 (Clockwise)

Preceding gene: 159896880

Following gene: 159896882

Centisome position: 6.62

GC content: 54.43

Gene sequence:

>654_bases
GTGGGTGAATTTCAGCAGGCCTTGGAGTATGCGCTTGAGCCGCGCAATTTGGCGCGATTAAGTGCCGCGCTCAATCGCCA
TGGGCAGCTTGTTGCTAGCGCGATGGCGATTGCGCTGCTACTAGGCTTGCCCTTTGGCTGGTGGAGCAGCCGCTCACGCC
TGATTAGCGCCATTGCGATCAATACCACCAATGGGCTGCGGGTCATTCCCAGCCTTGCCATCCTCTTTTTGTTTGTCGCA
ATCCCAGGCTTTGGCTTGAGTATTCGTTCGGCAATTATTGCCCTAACAATCTTGGCTTTGCCACCAATTTTGATCAATAC
CAATACGGCTTTTCGCACGCTCAACCCAGCTGTGCGCGAAGCCGCCAAGGCCATGGGTATGCCAGCATGGCTCCAACTAT
GGCGGGTCGAGTTGCCTTTAGCTGCGCCTGTCATTCTTTCGGGCATCCGCATCGCTTTGGTTGAGGTGATTGCCAGCGCC
ACCTTGGCTGCCTTTATTGGAGCTGGCGGGCTAGGCAGTTTTATCACTTTAGGATTTAGTATGAGCCGCGTCGATATTTT
GCTTGTTGGCGCTATTCCGGTGGCTTTGCTCGCAATTCTGGCCGAAATCGTCATGGCCGGGCTGTTGCGATGGGTGCAAC
CACCACAGTTTTAA

Upstream 100 bases:

>100_bases
TTGCGCGATCAATTAGTGGCTTTATTGCAAGCACTTTAGAGCTACTTTTTGCTGTAAATTGTGGTATGCTTTTTGAGGTT
TCCAACGTAGAGGAATGTGT

Downstream 100 bases:

>100_bases
GCTTGTTGGATAGGAGGATTCATGCGACGTTTCATCCAGCTAACCGTGTTGCTCACGCTCTTGATGACCATTTTAGCCGC
TTGTGGCGATGATGCAGCCA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MGEFQQALEYALEPRNLARLSAALNRHGQLVASAMAIALLLGLPFGWWSSRSRLISAIAINTTNGLRVIPSLAILFLFVA
IPGFGLSIRSAIIALTILALPPILINTNTAFRTLNPAVREAAKAMGMPAWLQLWRVELPLAAPVILSGIRIALVEVIASA
TLAAFIGAGGLGSFITLGFSMSRVDILLVGAIPVALLAILAEIVMAGLLRWVQPPQF

Sequences:

>Translated_217_residues
MGEFQQALEYALEPRNLARLSAALNRHGQLVASAMAIALLLGLPFGWWSSRSRLISAIAINTTNGLRVIPSLAILFLFVA
IPGFGLSIRSAIIALTILALPPILINTNTAFRTLNPAVREAAKAMGMPAWLQLWRVELPLAAPVILSGIRIALVEVIASA
TLAAFIGAGGLGSFITLGFSMSRVDILLVGAIPVALLAILAEIVMAGLLRWVQPPQF
>Mature_216_residues
GEFQQALEYALEPRNLARLSAALNRHGQLVASAMAIALLLGLPFGWWSSRSRLISAIAINTTNGLRVIPSLAILFLFVAI
PGFGLSIRSAIIALTILALPPILINTNTAFRTLNPAVREAAKAMGMPAWLQLWRVELPLAAPVILSGIRIALVEVIASAT
LAAFIGAGGLGSFITLGFSMSRVDILLVGAIPVALLAILAEIVMAGLLRWVQPPQF

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=197, Percent_Identity=32.48730964467, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788449, Length=136, Percent_Identity=40.4411764705882, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789033, Length=165, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23023; Mature: 22892

Theoretical pI: Translated: 11.99; Mature: 11.99

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEFQQALEYALEPRNLARLSAALNRHGQLVASAMAIALLLGLPFGWWSSRSRLISAIAI
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEE
NTTNGLRVIPSLAILFLFVAIPGFGLSIRSAIIALTILALPPILINTNTAFRTLNPAVRE
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHCCHHHHH
AAKAMGMPAWLQLWRVELPLAAPVILSGIRIALVEVIASATLAAFIGAGGLGSFITLGFS
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
MSRVDILLVGAIPVALLAILAEIVMAGLLRWVQPPQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GEFQQALEYALEPRNLARLSAALNRHGQLVASAMAIALLLGLPFGWWSSRSRLISAIAI
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEE
NTTNGLRVIPSLAILFLFVAIPGFGLSIRSAIIALTILALPPILINTNTAFRTLNPAVRE
ECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHCCHHHHH
AAKAMGMPAWLQLWRVELPLAAPVILSGIRIALVEVIASATLAAFIGAGGLGSFITLGFS
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
MSRVDILLVGAIPVALLAILAEIVMAGLLRWVQPPQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]