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The map label for this gene is clpB [H]

Identifier: 159896561

GI number: 159896561

Start: 34479

End: 36947

Strand: Reverse

Name: clpB [H]

Synonym: Haur_0028

Alternate gene names: 159896561

Gene position: 36947-34479 (Counterclockwise)

Preceding gene: 159896562

Following gene: 159896554

Centisome position: 0.58

GC content: 51.8

Gene sequence:

>2469_bases
ATGAAGTTAGAACGATTTACCGAAAAAGCGCAAGAAGCGTTTCAACATGCCCAAGAGTTGATGCACGAACAGCATCACTC
GCAGCTCGATGTTGAGCATATCTTCTTGGCGTTGTTGCGCCAATCGGATGGGATTGCCGGGCGGGTTTTGGGTCGCCTCA
GTGTCAATGTTGAATCAGTAATTGCCCGCGTCGAACGCGAGCTTGATAAATCACCCAAAGTTTATAACTATGGCTATCCG
CAGCAAAGCGTCTATGTAACGCCGCGCACGCAACGATTGGTCAAACGCGCCGAGCAAGAAGCTGAGCGCATGGGCGATCA
ATATGTCTCAACTGAGCATTTGTTGATTGCAATTGCTGGCGAACGCGAAGGTGCTTCCGCTCGTATTCTGGCCAGTTTTG
GCATCGACACCGAGCGCTTGCTTTCAATTTTGATGGAGATTCGTGGCTCGCAACGCGCCGATGATCCAACTGCCGAGAGC
CGTTATGAAGTGCTGGAAAAATATAGCACCGATCTAACCGCCCTGGCCTCTCAAGGCTTGCTTGACCCAGTAGTTGGCCG
CGATAGCGAAATTACCCGCGTGATTCGGATTTTGAGCCGACGCAGCAAAAATAACCCGGTGTTGGTAGGCGAAACTGGCG
TTGGTAAAACTGCCATTGCTGAAGGCTTAGCCCAACGCATTGCCAATGGCGATGTGCCCGAGTTGTTGCGCAATCGGCGG
GTGCTGGCGCTCGATTTGGCAGGCATGGTCGCCGGCTCTAAATTCCGTGGCGAGTTTGAAGAACGACTCAAAGCAGTGAT
GGATGAGGTGCGCTCGGCCAAAGGCAAAGTGATTGTCTTTATCGATGAATTACACACCGTGGTTGGGGCTGGCTCAGCGG
CTGGCTCAATCGATGCCTCGAATATGCTCAAACCAGCCTTGGCACGCGGTGAAATGCAGGCAGTTGGCGCGACTACCACC
GACGAATATCGCAAGCACATCGAAAAAGATGCAGCCTTGGAACGCCGTTTCTCCCCAGTCTATGTTGAAGAGCCAGATGT
TGAAACCACGATCGAAATGCTGCGTGGTTTACGCCGTCGCTACGAAGAACATCACAATTTGACGATTAGTGATGCTGCTT
TGAAAGCCGCCGCCAACCTCTCGCATCGCTATATCAACGATCGTTTCTTGCCCGATAAAGCCATCGACTTGATCGACGAA
GCTTCGGCCAAACTGCGAATTGATATTTATTCGATGCCCAAGGAGTTGCGCGAAAAGCAACAAGCAATTCGTGATTTGCA
TCGTGGCGAGGAAGATGCTGGCAATCAACGCGATTACGAACGCGCGGCGATTCTCAAAGCCGAAGCCTTGGCCTTGGAGA
GCGAATTTCAGCTTGAGCGCCAGCAATGGCTTGAAACCAATCAGCTCGATGATGTGGTCGATGAAGAAGATGTGGCCACG
ATCGTTGCCAACTGGACGGGGATTCCGGTGCAGCGTATGCTCGAAACCGAAAAACTCAAGTTGGTCGAGATGGAAGAACG
TTTGCATGCTCGCGTTGTTGGTCAACACGAAGCCGTAACCGCCGTTGCCGATGCGATTCGCCGTGCTCGATCTGGCCTCA
AAGACCCACGCCGACCAATTGGCTCATTCATTTTTGTGGGGCCAACTGGGGTTGGTAAAACCGAATTGGCTAAAGCCTTG
GCAGCCTTCTTGTTCGACGACGAAGATGCCATGACCCGCGTCGATATGTCGGAATACCAAGAACGTCACACGGTTTCGCG
CTTGGTTGGCGCACCTCCAGGCTATGTTGGCTACGACGAAGGCGGTCAATTAACCGAATCAATTCGTCGCCGCCCATATC
AAGTAATTTTGTTCGATGAAATTGAAAAAGCCCATGGCGATGTCTTCAATTCGTTGTTGCAAGTGCTTGATGATGGCCGC
TTGACCGATGCTCAAGGCCGCACCGTCGATTTCCGCAACACCGTGATCATTATGACCTCGAATGTGGGCACTGATGAGAT
TCGGGCTGGCTCGATTGGCTTCCGCCGCGAGAACAAAATTGATATGGGTGAAGTGCGCAAGCGGGTTGACGATGCCATGA
AACGCACCTTCCGACCTGAGTTCTTAAACCGCATCGATGAAATTATTCTGTTCAAGCCATTGGAAATGGCCGAATTGACT
GGAATTATCGATATCTTGGCCTCTGAAGTTGCAGGCCGTTTGGGCGAGTTGCAAATTACCTTGCATCTGACCCGCGCTGC
CAAGGAATTGTTGGTGCAAGAAGGCTACAACCCAGTGTATGGGGCACGTCCATTGCGCCGCACCTTGCAACGCTTGGTCG
AAACGCCGCTCTCACGCGCCTTGCTTAAAGGCGAATTCAGCGCTGGCGATGTGGTCGAAGTCGATGTTGAAAATGGTGTG
ATTATTTTCAACAAAGGCGAACGCTTGCAAATTACCAGTAGCAAGCCAGTTGAGCCACTTTCAGCCTAA

Upstream 100 bases:

>100_bases
GCTCTACGGGACAGCGAATAATGTCAGAAGGCAAAAATCAAAAGGCAAAAGGGTTTTGACTTCTGCCTTTTGACTTTTGA
TTTTGACAAAGGGTTTTTAT

Downstream 100 bases:

>100_bases
CCAAACTTGTATCGAAACAGCGGTCGGGAAGTTGCTTCCCGACCGCTGAATGGTTTAAGTCAACAAACGCACCACAATCG
CCGCATGCTTATCGCCTTCA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MKLERFTEKAQEAFQHAQELMHEQHHSQLDVEHIFLALLRQSDGIAGRVLGRLSVNVESVIARVERELDKSPKVYNYGYP
QQSVYVTPRTQRLVKRAEQEAERMGDQYVSTEHLLIAIAGEREGASARILASFGIDTERLLSILMEIRGSQRADDPTAES
RYEVLEKYSTDLTALASQGLLDPVVGRDSEITRVIRILSRRSKNNPVLVGETGVGKTAIAEGLAQRIANGDVPELLRNRR
VLALDLAGMVAGSKFRGEFEERLKAVMDEVRSAKGKVIVFIDELHTVVGAGSAAGSIDASNMLKPALARGEMQAVGATTT
DEYRKHIEKDAALERRFSPVYVEEPDVETTIEMLRGLRRRYEEHHNLTISDAALKAAANLSHRYINDRFLPDKAIDLIDE
ASAKLRIDIYSMPKELREKQQAIRDLHRGEEDAGNQRDYERAAILKAEALALESEFQLERQQWLETNQLDDVVDEEDVAT
IVANWTGIPVQRMLETEKLKLVEMEERLHARVVGQHEAVTAVADAIRRARSGLKDPRRPIGSFIFVGPTGVGKTELAKAL
AAFLFDDEDAMTRVDMSEYQERHTVSRLVGAPPGYVGYDEGGQLTESIRRRPYQVILFDEIEKAHGDVFNSLLQVLDDGR
LTDAQGRTVDFRNTVIIMTSNVGTDEIRAGSIGFRRENKIDMGEVRKRVDDAMKRTFRPEFLNRIDEIILFKPLEMAELT
GIIDILASEVAGRLGELQITLHLTRAAKELLVQEGYNPVYGARPLRRTLQRLVETPLSRALLKGEFSAGDVVEVDVENGV
IIFNKGERLQITSSKPVEPLSA

Sequences:

>Translated_822_residues
MKLERFTEKAQEAFQHAQELMHEQHHSQLDVEHIFLALLRQSDGIAGRVLGRLSVNVESVIARVERELDKSPKVYNYGYP
QQSVYVTPRTQRLVKRAEQEAERMGDQYVSTEHLLIAIAGEREGASARILASFGIDTERLLSILMEIRGSQRADDPTAES
RYEVLEKYSTDLTALASQGLLDPVVGRDSEITRVIRILSRRSKNNPVLVGETGVGKTAIAEGLAQRIANGDVPELLRNRR
VLALDLAGMVAGSKFRGEFEERLKAVMDEVRSAKGKVIVFIDELHTVVGAGSAAGSIDASNMLKPALARGEMQAVGATTT
DEYRKHIEKDAALERRFSPVYVEEPDVETTIEMLRGLRRRYEEHHNLTISDAALKAAANLSHRYINDRFLPDKAIDLIDE
ASAKLRIDIYSMPKELREKQQAIRDLHRGEEDAGNQRDYERAAILKAEALALESEFQLERQQWLETNQLDDVVDEEDVAT
IVANWTGIPVQRMLETEKLKLVEMEERLHARVVGQHEAVTAVADAIRRARSGLKDPRRPIGSFIFVGPTGVGKTELAKAL
AAFLFDDEDAMTRVDMSEYQERHTVSRLVGAPPGYVGYDEGGQLTESIRRRPYQVILFDEIEKAHGDVFNSLLQVLDDGR
LTDAQGRTVDFRNTVIIMTSNVGTDEIRAGSIGFRRENKIDMGEVRKRVDDAMKRTFRPEFLNRIDEIILFKPLEMAELT
GIIDILASEVAGRLGELQITLHLTRAAKELLVQEGYNPVYGARPLRRTLQRLVETPLSRALLKGEFSAGDVVEVDVENGV
IIFNKGERLQITSSKPVEPLSA
>Mature_822_residues
MKLERFTEKAQEAFQHAQELMHEQHHSQLDVEHIFLALLRQSDGIAGRVLGRLSVNVESVIARVERELDKSPKVYNYGYP
QQSVYVTPRTQRLVKRAEQEAERMGDQYVSTEHLLIAIAGEREGASARILASFGIDTERLLSILMEIRGSQRADDPTAES
RYEVLEKYSTDLTALASQGLLDPVVGRDSEITRVIRILSRRSKNNPVLVGETGVGKTAIAEGLAQRIANGDVPELLRNRR
VLALDLAGMVAGSKFRGEFEERLKAVMDEVRSAKGKVIVFIDELHTVVGAGSAAGSIDASNMLKPALARGEMQAVGATTT
DEYRKHIEKDAALERRFSPVYVEEPDVETTIEMLRGLRRRYEEHHNLTISDAALKAAANLSHRYINDRFLPDKAIDLIDE
ASAKLRIDIYSMPKELREKQQAIRDLHRGEEDAGNQRDYERAAILKAEALALESEFQLERQQWLETNQLDDVVDEEDVAT
IVANWTGIPVQRMLETEKLKLVEMEERLHARVVGQHEAVTAVADAIRRARSGLKDPRRPIGSFIFVGPTGVGKTELAKAL
AAFLFDDEDAMTRVDMSEYQERHTVSRLVGAPPGYVGYDEGGQLTESIRRRPYQVILFDEIEKAHGDVFNSLLQVLDDGR
LTDAQGRTVDFRNTVIIMTSNVGTDEIRAGSIGFRRENKIDMGEVRKRVDDAMKRTFRPEFLNRIDEIILFKPLEMAELT
GIIDILASEVAGRLGELQITLHLTRAAKELLVQEGYNPVYGARPLRRTLQRLVETPLSRALLKGEFSAGDVVEVDVENGV
IIFNKGERLQITSSKPVEPLSA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=319, Percent_Identity=38.2445141065831, Blast_Score=219, Evalue=7e-57,
Organism=Escherichia coli, GI1788943, Length=867, Percent_Identity=48.6735870818916, Blast_Score=775, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=791, Percent_Identity=38.0530973451327, Blast_Score=521, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6320464, Length=711, Percent_Identity=47.3980309423347, Blast_Score=630, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=881, Percent_Identity=37.3439273552781, Blast_Score=530, Evalue=1e-151,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 92137; Mature: 92137

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLERFTEKAQEAFQHAQELMHEQHHSQLDVEHIFLALLRQSDGIAGRVLGRLSVNVESV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
IARVERELDKSPKVYNYGYPQQSVYVTPRTQRLVKRAEQEAERMGDQYVSTEHLLIAIAG
HHHHHHHHCCCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
EREGASARILASFGIDTERLLSILMEIRGSQRADDPTAESRYEVLEKYSTDLTALASQGL
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCC
LDPVVGRDSEITRVIRILSRRSKNNPVLVGETGVGKTAIAEGLAQRIANGDVPELLRNRR
CCHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
VLALDLAGMVAGSKFRGEFEERLKAVMDEVRSAKGKVIVFIDELHTVVGAGSAAGSIDAS
EEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCHH
NMLKPALARGEMQAVGATTTDEYRKHIEKDAALERRFSPVYVEEPDVETTIEMLRGLRRR
HHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHH
YEEHHNLTISDAALKAAANLSHRYINDRFLPDKAIDLIDEASAKLRIDIYSMPKELREKQ
HHHHCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEHHHCCHHHHHHH
QAIRDLHRGEEDAGNQRDYERAAILKAEALALESEFQLERQQWLETNQLDDVVDEEDVAT
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHH
IVANWTGIPVQRMLETEKLKLVEMEERLHARVVGQHEAVTAVADAIRRARSGLKDPRRPI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
GSFIFVGPTGVGKTELAKALAAFLFDDEDAMTRVDMSEYQERHTVSRLVGAPPGYVGYDE
CCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTESIRRRPYQVILFDEIEKAHGDVFNSLLQVLDDGRLTDAQGRTVDFRNTVIIMTS
CCHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEC
NVGTDEIRAGSIGFRRENKIDMGEVRKRVDDAMKRTFRPEFLNRIDEIILFKPLEMAELT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
GIIDILASEVAGRLGELQITLHLTRAAKELLVQEGYNPVYGARPLRRTLQRLVETPLSRA
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGEFSAGDVVEVDVENGVIIFNKGERLQITSSKPVEPLSA
HHHCCCCCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKLERFTEKAQEAFQHAQELMHEQHHSQLDVEHIFLALLRQSDGIAGRVLGRLSVNVESV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
IARVERELDKSPKVYNYGYPQQSVYVTPRTQRLVKRAEQEAERMGDQYVSTEHLLIAIAG
HHHHHHHHCCCCCEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
EREGASARILASFGIDTERLLSILMEIRGSQRADDPTAESRYEVLEKYSTDLTALASQGL
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCC
LDPVVGRDSEITRVIRILSRRSKNNPVLVGETGVGKTAIAEGLAQRIANGDVPELLRNRR
CCHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
VLALDLAGMVAGSKFRGEFEERLKAVMDEVRSAKGKVIVFIDELHTVVGAGSAAGSIDAS
EEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCHH
NMLKPALARGEMQAVGATTTDEYRKHIEKDAALERRFSPVYVEEPDVETTIEMLRGLRRR
HHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHH
YEEHHNLTISDAALKAAANLSHRYINDRFLPDKAIDLIDEASAKLRIDIYSMPKELREKQ
HHHHCCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEHHHCCHHHHHHH
QAIRDLHRGEEDAGNQRDYERAAILKAEALALESEFQLERQQWLETNQLDDVVDEEDVAT
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHH
IVANWTGIPVQRMLETEKLKLVEMEERLHARVVGQHEAVTAVADAIRRARSGLKDPRRPI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
GSFIFVGPTGVGKTELAKALAAFLFDDEDAMTRVDMSEYQERHTVSRLVGAPPGYVGYDE
CCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTESIRRRPYQVILFDEIEKAHGDVFNSLLQVLDDGRLTDAQGRTVDFRNTVIIMTS
CCHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEEC
NVGTDEIRAGSIGFRRENKIDMGEVRKRVDDAMKRTFRPEFLNRIDEIILFKPLEMAELT
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
GIIDILASEVAGRLGELQITLHLTRAAKELLVQEGYNPVYGARPLRRTLQRLVETPLSRA
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGEFSAGDVVEVDVENGVIIFNKGERLQITSSKPVEPLSA
HHHCCCCCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]