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The map label for this gene is moeA [H]

Identifier: 159041301

GI number: 159041301

Start: 761369

End: 762628

Strand: Reverse

Name: moeA [H]

Synonym: Cmaq_0727

Alternate gene names: 159041301

Gene position: 762628-761369 (Counterclockwise)

Preceding gene: 159041302

Following gene: 159041298

Centisome position: 36.71

GC content: 38.81

Gene sequence:

>1260_bases
ATGAGACTTCATGAAGATAAGTATATTACGTTACATGATTTAAACGAAGTATTGAGTAATGCACCTAGGTGTAATCCTGA
GGTTAGTGAAATGGCACTATGGGATGCTGTGGGTTTAGTTTTAGCTAATGACATTATTGCACCGTTTGATACACCTATTA
TGCCTAAGGCTGTCTACGATGGGTTTGCGGTTAAGGCAGGTGAAACACCTGGTGTATTTAAGTTAGTTGGCTCAATACTA
ATAGGTCAATTACCTAACCGTGAATTGAGAGTAGGGGAGACGTATTATGTGACCACTGGAGCCTACTTACCTAAAGGAGC
TGATGTTGTTGTACCTGAGGAGGATGCTACTGTTAATGGTGATTCAGTAATAATTAATAAGGCATATTCAACAGGCGATA
ACATTGATGAACCTGGTTCATACGCCAAGAAGGGTCAATTACTTGTCAGTAAAGGCACAGTATTAACACCTTACATACTT
TCCGCACTACTTGAGACAGGGGTCTTTAAGGCTCAATTCTATAATAGACTTAAGGTTACTATAATTTCAACGGGCAGTGA
GTTGGTTAAACCAAGAACCCCTGAGGGGGCTTTAAATGAATTCATGACGGGTAAGGTTATTGAGAGCACTGGTTTATTAA
TTGAATGGTTTATGAGCAATTACATGCCTTATGTAACAGTATTAAAGCATATCATTATTAATGATTCTTACGATGAAATA
CTAAGTTCAGTTACCGATGGGTTAAGGAAATCAAACATTATAGTAATCACTGGTGGAACCAGACCAAGTGGTATTGATTA
CGTGCATGATACCTTAACAGCATTGAAACCCAAGTACTACGTTAGAGGTATTAAAATGAGACCAGGTAGACCATCCACCG
TTGCAGTATTCGATGACTGTCATGTAGCCTTTGGTGTAAGTGGACACCCAATAAGCGCATTAAATGCCTTAAGCCTATTA
ATAGAACCATTTGTAAGAAACATGTTAAGCATTGTGAGCACAGTGCCTTTACCCAAGGCCTATGGCAGGTTACTTGAATC
AACTGAACCAGGTAGGGGTCTTTGGAGACAGGTAAGAGCTAAGGTGGAGGTGGATAATAATGGTTATATTGTTAAACCAT
TGAAGATAACAGGTAGTTCATTCACATCCACCCTAGCTGAAGCAGATGCCTTAATTAACATTCCACCATGGGTTAATGAT
GCCGCAAAGGATTTAATAGTTGAAATGCTAATGCTTAGAAGCAGATCATTTAAATATTAA

Upstream 100 bases:

>100_bases
AGTACTTGATAAAGTATTAGCGCATAGATGCGACTATCCATTATTGAGAAAAAATCATTCGCAATGGGTTTAAAAACTAA
AGGTGAATTTATCATGCTTA

Downstream 100 bases:

>100_bases
TATGCTAAGTTAGACTAGAATAATGAACACCATGGACATGGACTTTACGTAACTGCAGCATTAATTTAAGTTGCTTCCTT
GCATCCAAATAAGTTATGCA

Product: MoeA domain-containing protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRLHEDKYITLHDLNEVLSNAPRCNPEVSEMALWDAVGLVLANDIIAPFDTPIMPKAVYDGFAVKAGETPGVFKLVGSIL
IGQLPNRELRVGETYYVTTGAYLPKGADVVVPEEDATVNGDSVIINKAYSTGDNIDEPGSYAKKGQLLVSKGTVLTPYIL
SALLETGVFKAQFYNRLKVTIISTGSELVKPRTPEGALNEFMTGKVIESTGLLIEWFMSNYMPYVTVLKHIIINDSYDEI
LSSVTDGLRKSNIIVITGGTRPSGIDYVHDTLTALKPKYYVRGIKMRPGRPSTVAVFDDCHVAFGVSGHPISALNALSLL
IEPFVRNMLSIVSTVPLPKAYGRLLESTEPGRGLWRQVRAKVEVDNNGYIVKPLKITGSSFTSTLAEADALINIPPWVND
AAKDLIVEMLMLRSRSFKY

Sequences:

>Translated_419_residues
MRLHEDKYITLHDLNEVLSNAPRCNPEVSEMALWDAVGLVLANDIIAPFDTPIMPKAVYDGFAVKAGETPGVFKLVGSIL
IGQLPNRELRVGETYYVTTGAYLPKGADVVVPEEDATVNGDSVIINKAYSTGDNIDEPGSYAKKGQLLVSKGTVLTPYIL
SALLETGVFKAQFYNRLKVTIISTGSELVKPRTPEGALNEFMTGKVIESTGLLIEWFMSNYMPYVTVLKHIIINDSYDEI
LSSVTDGLRKSNIIVITGGTRPSGIDYVHDTLTALKPKYYVRGIKMRPGRPSTVAVFDDCHVAFGVSGHPISALNALSLL
IEPFVRNMLSIVSTVPLPKAYGRLLESTEPGRGLWRQVRAKVEVDNNGYIVKPLKITGSSFTSTLAEADALINIPPWVND
AAKDLIVEMLMLRSRSFKY
>Mature_419_residues
MRLHEDKYITLHDLNEVLSNAPRCNPEVSEMALWDAVGLVLANDIIAPFDTPIMPKAVYDGFAVKAGETPGVFKLVGSIL
IGQLPNRELRVGETYYVTTGAYLPKGADVVVPEEDATVNGDSVIINKAYSTGDNIDEPGSYAKKGQLLVSKGTVLTPYIL
SALLETGVFKAQFYNRLKVTIISTGSELVKPRTPEGALNEFMTGKVIESTGLLIEWFMSNYMPYVTVLKHIIINDSYDEI
LSSVTDGLRKSNIIVITGGTRPSGIDYVHDTLTALKPKYYVRGIKMRPGRPSTVAVFDDCHVAFGVSGHPISALNALSLL
IEPFVRNMLSIVSTVPLPKAYGRLLESTEPGRGLWRQVRAKVEVDNNGYIVKPLKITGSSFTSTLAEADALINIPPWVND
AAKDLIVEMLMLRSRSFKY

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=315, Percent_Identity=29.2063492063492, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI10880983, Length=315, Percent_Identity=29.2063492063492, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI1787049, Length=372, Percent_Identity=24.1935483870968, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25147659, Length=308, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562606, Length=356, Percent_Identity=25, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136978, Length=293, Percent_Identity=27.9863481228669, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24638841, Length=293, Percent_Identity=27.9863481228669, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 45914; Mature: 45914

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLHEDKYITLHDLNEVLSNAPRCNPEVSEMALWDAVGLVLANDIIAPFDTPIMPKAVYD
CCCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
GFAVKAGETPGVFKLVGSILIGQLPNRELRVGETYYVTTGAYLPKGADVVVPEEDATVNG
CEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCCCCCCEEEECCCCCEECC
DSVIINKAYSTGDNIDEPGSYAKKGQLLVSKGTVLTPYILSALLETGVFKAQFYNRLKVT
CEEEEEECCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHCEEEEE
IISTGSELVKPRTPEGALNEFMTGKVIESTGLLIEWFMSNYMPYVTVLKHIIINDSYDEI
EEECCHHHCCCCCCCHHHHHHHCCCEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
LSSVTDGLRKSNIIVITGGTRPSGIDYVHDTLTALKPKYYVRGIKMRPGRPSTVAVFDDC
HHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCHHEEEEEECCCCCCEEEEEECC
HVAFGVSGHPISALNALSLLIEPFVRNMLSIVSTVPLPKAYGRLLESTEPGRGLWRQVRA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHE
KVEVDNNGYIVKPLKITGSSFTSTLAEADALINIPPWVNDAAKDLIVEMLMLRSRSFKY
EEEECCCCEEEEEEEECCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLHEDKYITLHDLNEVLSNAPRCNPEVSEMALWDAVGLVLANDIIAPFDTPIMPKAVYD
CCCCCCCEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHC
GFAVKAGETPGVFKLVGSILIGQLPNRELRVGETYYVTTGAYLPKGADVVVPEEDATVNG
CEEEECCCCCHHHHHHHHHHHCCCCCCCEEECCEEEEEECCCCCCCCEEEECCCCCEECC
DSVIINKAYSTGDNIDEPGSYAKKGQLLVSKGTVLTPYILSALLETGVFKAQFYNRLKVT
CEEEEEECCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHCEEEEE
IISTGSELVKPRTPEGALNEFMTGKVIESTGLLIEWFMSNYMPYVTVLKHIIINDSYDEI
EEECCHHHCCCCCCCHHHHHHHCCCEECCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
LSSVTDGLRKSNIIVITGGTRPSGIDYVHDTLTALKPKYYVRGIKMRPGRPSTVAVFDDC
HHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCHHEEEEEECCCCCCEEEEEECC
HVAFGVSGHPISALNALSLLIEPFVRNMLSIVSTVPLPKAYGRLLESTEPGRGLWRQVRA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHE
KVEVDNNGYIVKPLKITGSSFTSTLAEADALINIPPWVNDAAKDLIVEMLMLRSRSFKY
EEEECCCCEEEEEEEECCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA