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The map label for this gene is map [H]

Identifier: 158425564

GI number: 158425564

Start: 4505470

End: 4506225

Strand: Direct

Name: map [H]

Synonym: AZC_3940

Alternate gene names: 158425564

Gene position: 4505470-4506225 (Clockwise)

Preceding gene: 158425563

Following gene: 158425566

Centisome position: 83.9

GC content: 67.59

Gene sequence:

>756_bases
ATGACGCTGTCGAATGACGACGAGCTGAAGGCAATGCAGGAGATCGGCCGCATCTGCGCCGAGACGCTGGAGGCGATGAG
CAAGGCGATCGAGCCCGGCATCACCACCCGCGAGCTGGACGGGATCGGCCGGGCCTTTCTGGAGGCCGCCGGCGCGCAGT
CGGCGCCCGAGACGGTCTATGATTTTCCCGGCGCCACCTGCATCAGCATCAATGAGGAAGTCGCCCACGGCATTCCCGGC
GACCGCGTCATCCGGCCCGGCGATCTCGTGAACATTGACGTTTCGGCGCACAAGAACGGCTATTTCGCCGACACCGGCGC
CTCCTTCGCCGTGCCACCGGTGACGCGGGCGGTGGAGAAGCTCTGCCGCGACGGACGCCGCGCCATGTGGGCGGGCCTGC
GGCAGGTGGCGCCGGGCCGCCTGCTGGCGGGCATCGGTCAGGCTGTGGGCGCCTTTGCCAAGAAGAACGGCTATACGCTG
GTGCGCAATCTCGCGAGCCACGGCGTCGGCCTCTCGCTGCACGAGGAGCCCACCGAAATCGCCACCTGGCCGGATGCCTC
CGATCGCCGGATCATCACGGAAGGGCTGGTGTTCACGGTGGAGCCCTTCCTGTCGCTCGGCGCGACCCTCGCCGAAAATG
TCGAGGACGATCCGTGGACGCTCTATAGCGAACCTCGCGCCCTCACGGTCCAGTACGAGCACACGGTGGTCGCCACCCGC
AACGGCCCGCTCGTGCTGACCATGCCGGGGCATTAA

Upstream 100 bases:

>100_bases
CTCGGCCGAGACGCGGGTGGTGGAGCGGCCCGGATTGTCCCCCCTCGTCTATTCGCCGCGCTCGGCGCGATGATGCAGGG
CTGATGCGAAAGGACAGGCC

Downstream 100 bases:

>100_bases
AGCGCGCTTCTGTGTGCGCGGGTCCGGCTCTGGGTGTCGGGCGCGTTCGTCCTTTCGAGCCAGTGCGCCACCTCTTCCAC
CGTCTCCACCGCCGGCACAT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTLSNDDELKAMQEIGRICAETLEAMSKAIEPGITTRELDGIGRAFLEAAGAQSAPETVYDFPGATCISINEEVAHGIPG
DRVIRPGDLVNIDVSAHKNGYFADTGASFAVPPVTRAVEKLCRDGRRAMWAGLRQVAPGRLLAGIGQAVGAFAKKNGYTL
VRNLASHGVGLSLHEEPTEIATWPDASDRRIITEGLVFTVEPFLSLGATLAENVEDDPWTLYSEPRALTVQYEHTVVATR
NGPLVLTMPGH

Sequences:

>Translated_251_residues
MTLSNDDELKAMQEIGRICAETLEAMSKAIEPGITTRELDGIGRAFLEAAGAQSAPETVYDFPGATCISINEEVAHGIPG
DRVIRPGDLVNIDVSAHKNGYFADTGASFAVPPVTRAVEKLCRDGRRAMWAGLRQVAPGRLLAGIGQAVGAFAKKNGYTL
VRNLASHGVGLSLHEEPTEIATWPDASDRRIITEGLVFTVEPFLSLGATLAENVEDDPWTLYSEPRALTVQYEHTVVATR
NGPLVLTMPGH
>Mature_250_residues
TLSNDDELKAMQEIGRICAETLEAMSKAIEPGITTRELDGIGRAFLEAAGAQSAPETVYDFPGATCISINEEVAHGIPGD
RVIRPGDLVNIDVSAHKNGYFADTGASFAVPPVTRAVEKLCRDGRRAMWAGLRQVAPGRLLAGIGQAVGAFAKKNGYTLV
RNLASHGVGLSLHEEPTEIATWPDASDRRIITEGLVFTVEPFLSLGATLAENVEDDPWTLYSEPRALTVQYEHTVVATRN
GPLVLTMPGH

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=247, Percent_Identity=29.1497975708502, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=28.968253968254, Blast_Score=132, Evalue=3e-31,
Organism=Escherichia coli, GI1786364, Length=250, Percent_Identity=36, Blast_Score=174, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=29.8804780876494, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323273, Length=246, Percent_Identity=30.0813008130081, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355531, Length=246, Percent_Identity=32.9268292682927, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24583427, Length=241, Percent_Identity=30.2904564315353, Blast_Score=113, Evalue=9e-26,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26906; Mature: 26775

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSNDDELKAMQEIGRICAETLEAMSKAIEPGITTRELDGIGRAFLEAAGAQSAPETVY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
DFPGATCISINEEVAHGIPGDRVIRPGDLVNIDVSAHKNGYFADTGASFAVPPVTRAVEK
HCCCCEEEEECHHHHCCCCCCCEECCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHH
LCRDGRRAMWAGLRQVAPGRLLAGIGQAVGAFAKKNGYTLVRNLASHGVGLSLHEEPTEI
HHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEECCCCCCE
ATWPDASDRRIITEGLVFTVEPFLSLGATLAENVEDDPWTLYSEPRALTVQYEHTVVATR
ECCCCCCCCEEEECCCEEEEHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEEEEEEC
NGPLVLTMPGH
CCCEEEEECCC
>Mature Secondary Structure 
TLSNDDELKAMQEIGRICAETLEAMSKAIEPGITTRELDGIGRAFLEAAGAQSAPETVY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
DFPGATCISINEEVAHGIPGDRVIRPGDLVNIDVSAHKNGYFADTGASFAVPPVTRAVEK
HCCCCEEEEECHHHHCCCCCCCEECCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHH
LCRDGRRAMWAGLRQVAPGRLLAGIGQAVGAFAKKNGYTLVRNLASHGVGLSLHEEPTEI
HHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEECCCCCCE
ATWPDASDRRIITEGLVFTVEPFLSLGATLAENVEDDPWTLYSEPRALTVQYEHTVVATR
ECCCCCCCCEEEECCCEEEEHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEEEEEEC
NGPLVLTMPGH
CCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA