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The map label for this gene is cobL [H]

Identifier: 158425566

GI number: 158425566

Start: 4507042

End: 4508283

Strand: Direct

Name: cobL [H]

Synonym: AZC_3942

Alternate gene names: 158425566

Gene position: 4507042-4508283 (Clockwise)

Preceding gene: 158425564

Following gene: 158425567

Centisome position: 83.93

GC content: 74.15

Gene sequence:

>1242_bases
ATGGCGGGCGACACTGCCGCAGCACGGCCCTGGCTGTCCATCGTCGGCATCGGTGAGGATGGCGCGGACGGCCTCTCCCC
CGCCGCACGCGCGCTGGTCGGCGACGCAGAGCTGGTGTTCGGCGGTGCCCGGCATCTGGCGCTGGCGGGCGCCCTCGTGC
GCGGCACGCCGTGCCCCTGGCCCAGCCCGTTCTCGGAGGGCATCGCGCAGGTGGTGGCGGCGCGCGGCCGAAAGGTGTGC
GTGCTCGCCTCCGGCGATCCTTTCCTGCACGGCGTCGGCGCCACACTCTCCCGGCACGTCCCGGCGGATGAGATGCAGGT
CCTGCCCGCGCCCTCCGCCTTCAGCCTCGCGGCGGCCCGGCTCGGCTGGCCCTTGCAGGAGACGGCGCAGGTCTCCCTGC
ACGGCAAGGCCATCGGCCGCATCCGGCCCTTTCTGCAACCGGGCGCCCGCATCCTGGCCCTGACCTCGGACGGCGACGGT
CCCGCGCAGGTGGCGTGCCTCCTCGCCGCGCTCGGCTTCGGCGCGGCGCGGCTCACCGTGCTGGAAGCCCTCGGCGGCCC
GCGCGCGCGGATGCGCACGGCGACGGCCGCCGGCTTCGATCTCGCGGATGTCGATCCGCTGAACATCCTCGCCCTGGAAG
TCCCGGCGGACACAGCCCCGCAGGCCCTGCCGCTCACCTGCGGCCTGCCGGACGAGCTGTTCGAGCATGACGGCCAGCTC
ACCAAGCGCGAGATCCGCGCCGTCACCTTGTCCGCCCTCGCGCCGCGCGCGGGCGAGCATCTGTGGGACGTGGGCGGGGG
CGCGGGCTCCGTCGCCATCGAATGGCTGCTGACGCACCCCTCCCTGTCGGCCACCGCCATCGAGCAGGACGAAACCCGCG
CCGAGCGCATCCGGGCCAATGCGGGCAATCTGGGGGTGCCGCACCTTGCCGTCGTCACGGGCATCGCGCCGCAGGCTTAT
GCGGGCCTGCCGCAGCCCGATGTCGTGTTCATCGGCGGCGGCGGGTCCGAGCCGGGTGTCCTCGCCGGAGCCCTCGCAGC
ATTGAAGCCGGGCGGGCGCCTTGTCGCCAATGCCGTCACGCTGGAGACCGAAGCCGTGCTTCTGGAGCATTACGCCCGCC
TCGGCGGCAGCCTCGCGCGGCTGTCCGTGTCCCGCGCCGTGCCGGTGAAGGGCATGACCGGCTGGCGCCCGGCGATGCCG
GTCACGCAGTGGAGCGTCGTCAAGGCGGGAGCGTCCGCATGA

Upstream 100 bases:

>100_bases
GCCTGCGAGTCGCGCGGCGAGACGCCGGGCCTCCCCTGTCCCCCCAAGGATGAGGATGTGACGCGGCATGGATGCGGCTT
GGCTGAGCGAGGGACCTGAC

Downstream 100 bases:

>100_bases
TCGCGGCGGGTATCGGCAGCAAGCGGGGCGTGACCGCACAGGACGTGCTCGCCGCCATCGACGCAGCGCTGGAGCGGGTG
CACCTGTCGCGCGAGGATCT

Product: precorrin-6Y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAGDTAAARPWLSIVGIGEDGADGLSPAARALVGDAELVFGGARHLALAGALVRGTPCPWPSPFSEGIAQVVAARGRKVC
VLASGDPFLHGVGATLSRHVPADEMQVLPAPSAFSLAAARLGWPLQETAQVSLHGKAIGRIRPFLQPGARILALTSDGDG
PAQVACLLAALGFGAARLTVLEALGGPRARMRTATAAGFDLADVDPLNILALEVPADTAPQALPLTCGLPDELFEHDGQL
TKREIRAVTLSALAPRAGEHLWDVGGGAGSVAIEWLLTHPSLSATAIEQDETRAERIRANAGNLGVPHLAVVTGIAPQAY
AGLPQPDVVFIGGGGSEPGVLAGALAALKPGGRLVANAVTLETEAVLLEHYARLGGSLARLSVSRAVPVKGMTGWRPAMP
VTQWSVVKAGASA

Sequences:

>Translated_413_residues
MAGDTAAARPWLSIVGIGEDGADGLSPAARALVGDAELVFGGARHLALAGALVRGTPCPWPSPFSEGIAQVVAARGRKVC
VLASGDPFLHGVGATLSRHVPADEMQVLPAPSAFSLAAARLGWPLQETAQVSLHGKAIGRIRPFLQPGARILALTSDGDG
PAQVACLLAALGFGAARLTVLEALGGPRARMRTATAAGFDLADVDPLNILALEVPADTAPQALPLTCGLPDELFEHDGQL
TKREIRAVTLSALAPRAGEHLWDVGGGAGSVAIEWLLTHPSLSATAIEQDETRAERIRANAGNLGVPHLAVVTGIAPQAY
AGLPQPDVVFIGGGGSEPGVLAGALAALKPGGRLVANAVTLETEAVLLEHYARLGGSLARLSVSRAVPVKGMTGWRPAMP
VTQWSVVKAGASA
>Mature_412_residues
AGDTAAARPWLSIVGIGEDGADGLSPAARALVGDAELVFGGARHLALAGALVRGTPCPWPSPFSEGIAQVVAARGRKVCV
LASGDPFLHGVGATLSRHVPADEMQVLPAPSAFSLAAARLGWPLQETAQVSLHGKAIGRIRPFLQPGARILALTSDGDGP
AQVACLLAALGFGAARLTVLEALGGPRARMRTATAAGFDLADVDPLNILALEVPADTAPQALPLTCGLPDELFEHDGQLT
KREIRAVTLSALAPRAGEHLWDVGGGAGSVAIEWLLTHPSLSATAIEQDETRAERIRANAGNLGVPHLAVVTGIAPQAYA
GLPQPDVVFIGGGGSEPGVLAGALAALKPGGRLVANAVTLETEAVLLEHYARLGGSLARLSVSRAVPVKGMTGWRPAMPV
TQWSVVKAGASA

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 42051; Mature: 41920

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGDTAAARPWLSIVGIGEDGADGLSPAARALVGDAELVFGGARHLALAGALVRGTPCPW
CCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCC
PSPFSEGIAQVVAARGRKVCVLASGDPFLHGVGATLSRHVPADEMQVLPAPSAFSLAAAR
CCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCHHHHCCCCCCHHEEECCCCHHHHHHHH
LGWPLQETAQVSLHGKAIGRIRPFLQPGARILALTSDGDGPAQVACLLAALGFGAARLTV
HCCCHHHHHEEEECCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHH
LEALGGPRARMRTATAAGFDLADVDPLNILALEVPADTAPQALPLTCGLPDELFEHDGQL
HHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHCCCCH
TKREIRAVTLSALAPRAGEHLWDVGGGAGSVAIEWLLTHPSLSATAIEQDETRAERIRAN
HHHHHHHHHHHHHCCCCCCHHEECCCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHCC
AGNLGVPHLAVVTGIAPQAYAGLPQPDVVFIGGGGSEPGVLAGALAALKPGGRLVANAVT
CCCCCCCHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEE
LETEAVLLEHYARLGGSLARLSVSRAVPVKGMTGWRPAMPVTQWSVVKAGASA
EHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCCCCCCCHHEECCCCCC
>Mature Secondary Structure 
AGDTAAARPWLSIVGIGEDGADGLSPAARALVGDAELVFGGARHLALAGALVRGTPCPW
CCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCC
PSPFSEGIAQVVAARGRKVCVLASGDPFLHGVGATLSRHVPADEMQVLPAPSAFSLAAAR
CCHHHHHHHHHHHHCCCEEEEEECCCCCEEECCHHHHCCCCCCHHEEECCCCHHHHHHHH
LGWPLQETAQVSLHGKAIGRIRPFLQPGARILALTSDGDGPAQVACLLAALGFGAARLTV
HCCCHHHHHEEEECCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHH
LEALGGPRARMRTATAAGFDLADVDPLNILALEVPADTAPQALPLTCGLPDELFEHDGQL
HHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHCCCCH
TKREIRAVTLSALAPRAGEHLWDVGGGAGSVAIEWLLTHPSLSATAIEQDETRAERIRAN
HHHHHHHHHHHHHCCCCCCHHEECCCCCCCEEEEEEEECCCCCEEEECCHHHHHHHHHCC
AGNLGVPHLAVVTGIAPQAYAGLPQPDVVFIGGGGSEPGVLAGALAALKPGGRLVANAVT
CCCCCCCHHHHHHCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEEE
LETEAVLLEHYARLGGSLARLSVSRAVPVKGMTGWRPAMPVTQWSVVKAGASA
EHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCCCCCCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]