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The map label for this gene is cobJ [H]

Identifier: 158425563

GI number: 158425563

Start: 4504690

End: 4505442

Strand: Direct

Name: cobJ [H]

Synonym: AZC_3939

Alternate gene names: 158425563

Gene position: 4504690-4505442 (Clockwise)

Preceding gene: 158425562

Following gene: 158425564

Centisome position: 83.89

GC content: 72.64

Gene sequence:

>753_bases
GTGAGCGGGTCGCTCACCGTGGTGGGCCTCGGCCCCGGTGCCGCCCAGCAGATGACGCCGGAGGCCGTGGCCGCGCTGGA
GGCGGCGGACGAACTCTTCGGCTACGGCCCCTATCTCGCCCGCGCGCCGGAACGGCCGGGGCAGGTGCGCCACGCCTCCG
ACAATCGCGAGGAACTGGACCGCGCCCGCGCCGCCCTCGACCGGGCGGTGGCCGGCGCGCAGGTGGCGATGGTGTCGGGC
GGCGATGCGGGCGTCTTCGCCATGGCGGCGGCTGTCTGCGAGGCGGTGGAAAAGGGGCCGGACGCCTATCGCACCGTGGA
GCTTTCCGTCGTGCCGGGCGTCACTGCCATGCTGGCGGTGGCTGCGCGCATCGGCGCGCCGCTGGGGCACGATTTCTGCG
CCATCTCGCTCTCCGACAATCTGAAGCCGTGGGAGCTCGTCACCGCCCGCCTCAAGGCGGCGGCGCAGGCGGGCTTCGTG
ATCGCGCTTTATAATCCCATCAGTAAGGCGCGGCCCTGGCAGCTCGGCTCCGCCTTCGACCTGCTGCGCGAGGTGCTGCC
GGGAACCGTGCCCGTCATCTTCGGCCGAGCCGCCGGCCGGACGGACGAGCGCATCACCCTTGCCACGCTCTCGGAGGCTG
ATGCCGGCGTCGCGGACATGGCCACCTGCGTCATCATCGGCTCGGCCGAGACGCGGGTGGTGGAGCGGCCCGGATTGTCC
CCCCTCGTCTATTCGCCGCGCTCGGCGCGATGA

Upstream 100 bases:

>100_bases
GCACCATGGCGGAGAGCTATGTGGTGCCGCTCGCCGAGCGCAATGACGACCGCGCGCCCTATTTCGCCATCGTGCTGGTG
CCCGGCTGGGAGCGCGCCGC

Downstream 100 bases:

>100_bases
TGCAGGGCTGATGCGAAAGGACAGGCCATGACGCTGTCGAATGACGACGAGCTGAAGGCAATGCAGGAGATCGGCCGCAT
CTGCGCCGAGACGCTGGAGG

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSGSLTVVGLGPGAAQQMTPEAVAALEAADELFGYGPYLARAPERPGQVRHASDNREELDRARAALDRAVAGAQVAMVSG
GDAGVFAMAAAVCEAVEKGPDAYRTVELSVVPGVTAMLAVAARIGAPLGHDFCAISLSDNLKPWELVTARLKAAAQAGFV
IALYNPISKARPWQLGSAFDLLREVLPGTVPVIFGRAAGRTDERITLATLSEADAGVADMATCVIIGSAETRVVERPGLS
PLVYSPRSAR

Sequences:

>Translated_250_residues
MSGSLTVVGLGPGAAQQMTPEAVAALEAADELFGYGPYLARAPERPGQVRHASDNREELDRARAALDRAVAGAQVAMVSG
GDAGVFAMAAAVCEAVEKGPDAYRTVELSVVPGVTAMLAVAARIGAPLGHDFCAISLSDNLKPWELVTARLKAAAQAGFV
IALYNPISKARPWQLGSAFDLLREVLPGTVPVIFGRAAGRTDERITLATLSEADAGVADMATCVIIGSAETRVVERPGLS
PLVYSPRSAR
>Mature_249_residues
SGSLTVVGLGPGAAQQMTPEAVAALEAADELFGYGPYLARAPERPGQVRHASDNREELDRARAALDRAVAGAQVAMVSGG
DAGVFAMAAAVCEAVEKGPDAYRTVELSVVPGVTAMLAVAARIGAPLGHDFCAISLSDNLKPWELVTARLKAAAQAGFVI
ALYNPISKARPWQLGSAFDLLREVLPGTVPVIFGRAAGRTDERITLATLSEADAGVADMATCVIIGSAETRVVERPGLSP
LVYSPRSAR

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 25894; Mature: 25763

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSLTVVGLGPGAAQQMTPEAVAALEAADELFGYGPYLARAPERPGQVRHASDNREELD
CCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHH
RARAALDRAVAGAQVAMVSGGDAGVFAMAAAVCEAVEKGPDAYRTVELSVVPGVTAMLAV
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHH
AARIGAPLGHDFCAISLSDNLKPWELVTARLKAAAQAGFVIALYNPISKARPWQLGSAFD
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHH
LLREVLPGTVPVIFGRAAGRTDERITLATLSEADAGVADMATCVIIGSAETRVVERPGLS
HHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHEEEEEECCCCCEEEECCCCC
PLVYSPRSAR
CEECCCCCCC
>Mature Secondary Structure 
SGSLTVVGLGPGAAQQMTPEAVAALEAADELFGYGPYLARAPERPGQVRHASDNREELD
CCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHH
RARAALDRAVAGAQVAMVSGGDAGVFAMAAAVCEAVEKGPDAYRTVELSVVPGVTAMLAV
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHH
AARIGAPLGHDFCAISLSDNLKPWELVTARLKAAAQAGFVIALYNPISKARPWQLGSAFD
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHH
LLREVLPGTVPVIFGRAAGRTDERITLATLSEADAGVADMATCVIIGSAETRVVERPGLS
HHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHEEEEEECCCCCEEEECCCCC
PLVYSPRSAR
CEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]