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The map label for this gene is cobI [H]

Identifier: 158425562

GI number: 158425562

Start: 4503959

End: 4504693

Strand: Direct

Name: cobI [H]

Synonym: AZC_3938

Alternate gene names: 158425562

Gene position: 4503959-4504693 (Clockwise)

Preceding gene: 158425561

Following gene: 158425563

Centisome position: 83.88

GC content: 70.07

Gene sequence:

>735_bases
GTGAACGCCGCCATCGGACAGCTCATCGGCGTCGGCGTCGGCCCCGGCGATCCCGAACTCATGACGCTCAAGGCCGTGCG
CGCGCTGGAGCAGGCGGACGTGATCGCCCACTTCGCCAAGGCGGGCAACAACAGCCACGCCCGCACCATTGCCGGCGCAC
ACTTCCGCCCAGGGGCGGAAGAACTGCCCCTGCTCTATCCGGTGACGACCGAGATTCACCGCCATGACGAGGCCTACAAG
CTCGCCATCGGCGCCTTCTATGACGAATCCGCCGCGCGGGTCGCCGAGCGCCTCATGGCCGGGCTCAATGTGGCGGTGCT
GAGCGAGGGCGATCCCCTCTTCTATGGCTCCTACATGCATCTGCATGTGCGCCTCGCCCACCGCTTTCCCACGCGGGTCA
TTCCCGGCGTCACCGGCATGTCCGGCTGCTGGTCGCAGGCGGGGGCGCCCATCGCGCAGGGCGATGATGTGCTGATGGTG
CTGCCCGGCACGCTGGACGAGCCGGAGCTGGCCCGCCGCCTTGCCGAGGCGGATGCCGCCGTCATCATGAAGGTGGGCCG
CAACCTGCCGAAGATCCGCCGCGCGCTCGCCGCAGCCGGCCGCCTGCCGCGCGCGCTCTATGTGGAGCGGGGCACCATGG
CGGAGAGCTATGTGGTGCCGCTCGCCGAGCGCAATGACGACCGCGCGCCCTATTTCGCCATCGTGCTGGTGCCCGGCTGG
GAGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
CGGAAAACCCGCGCGGCGTGCCCTTCGCCATCGTGCGCGGGCGGCTGGGCGGCAGCGCCATCACCGCCGCCGCCGTCAAC
GCACTCGCGAGGGCCGGGCT

Downstream 100 bases:

>100_bases
GCGGGTCGCTCACCGTGGTGGGCCTCGGCCCCGGTGCCGCCCAGCAGATGACGCCGGAGGCCGTGGCCGCGCTGGAGGCG
GCGGACGAACTCTTCGGCTA

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MNAAIGQLIGVGVGPGDPELMTLKAVRALEQADVIAHFAKAGNNSHARTIAGAHFRPGAEELPLLYPVTTEIHRHDEAYK
LAIGAFYDESAARVAERLMAGLNVAVLSEGDPLFYGSYMHLHVRLAHRFPTRVIPGVTGMSGCWSQAGAPIAQGDDVLMV
LPGTLDEPELARRLAEADAAVIMKVGRNLPKIRRALAAAGRLPRALYVERGTMAESYVVPLAERNDDRAPYFAIVLVPGW
ERAA

Sequences:

>Translated_244_residues
MNAAIGQLIGVGVGPGDPELMTLKAVRALEQADVIAHFAKAGNNSHARTIAGAHFRPGAEELPLLYPVTTEIHRHDEAYK
LAIGAFYDESAARVAERLMAGLNVAVLSEGDPLFYGSYMHLHVRLAHRFPTRVIPGVTGMSGCWSQAGAPIAQGDDVLMV
LPGTLDEPELARRLAEADAAVIMKVGRNLPKIRRALAAAGRLPRALYVERGTMAESYVVPLAERNDDRAPYFAIVLVPGW
ERAA
>Mature_244_residues
MNAAIGQLIGVGVGPGDPELMTLKAVRALEQADVIAHFAKAGNNSHARTIAGAHFRPGAEELPLLYPVTTEIHRHDEAYK
LAIGAFYDESAARVAERLMAGLNVAVLSEGDPLFYGSYMHLHVRLAHRFPTRVIPGVTGMSGCWSQAGAPIAQGDDVLMV
LPGTLDEPELARRLAEADAAVIMKVGRNLPKIRRALAAAGRLPRALYVERGTMAESYVVPLAERNDDRAPYFAIVLVPGW
ERAA

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26250; Mature: 26250

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAIGQLIGVGVGPGDPELMTLKAVRALEQADVIAHFAKAGNNSHARTIAGAHFRPGAE
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
ELPLLYPVTTEIHRHDEAYKLAIGAFYDESAARVAERLMAGLNVAVLSEGDPLFYGSYMH
CCCEEEECHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCEEECCEEE
LHVRLAHRFPTRVIPGVTGMSGCWSQAGAPIAQGDDVLMVLPGTLDEPELARRLAEADAA
EEEEEHHHCCHHHCCCCCCCCHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
VIMKVGRNLPKIRRALAAAGRLPRALYVERGTMAESYVVPLAERNDDRAPYFAIVLVPGW
HHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEHHCCCCCCCCEEEEEEECCC
ERAA
CCCC
>Mature Secondary Structure
MNAAIGQLIGVGVGPGDPELMTLKAVRALEQADVIAHFAKAGNNSHARTIAGAHFRPGAE
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
ELPLLYPVTTEIHRHDEAYKLAIGAFYDESAARVAERLMAGLNVAVLSEGDPLFYGSYMH
CCCEEEECHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCEEECCEEE
LHVRLAHRFPTRVIPGVTGMSGCWSQAGAPIAQGDDVLMVLPGTLDEPELARRLAEADAA
EEEEEHHHCCHHHCCCCCCCCHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
VIMKVGRNLPKIRRALAAAGRLPRALYVERGTMAESYVVPLAERNDDRAPYFAIVLVPGW
HHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEHHCCCCCCCCEEEEEEECCC
ERAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]