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The map label for this gene is dprE1 [H]

Identifier: 158425433

GI number: 158425433

Start: 4362471

End: 4363793

Strand: Reverse

Name: dprE1 [H]

Synonym: AZC_3809

Alternate gene names: 158425433

Gene position: 4363793-4362471 (Counterclockwise)

Preceding gene: 158425434

Following gene: 158425432

Centisome position: 81.27

GC content: 54.5

Gene sequence:

>1323_bases
ATGATTTTGTCAGGCTGGGGACGCTATCCTCGTGTCGACGCACGGGTCTTCGCTCCCCGTGTGGAAACTGAAATCGAGCA
AGTAATTCGTAGTCAGCGAACTCTGATAGGAAGAGGTGCCGGATTGGCGTACGGTGATTGCGCCATAAGCGTTGGTGCCA
CTGTCGAAATGAGACGTCTCGCGGGGATTGAGCTTTTCGACGATGCGGCGGGTATTCTCACTGCCCAAGCGGGCGTGACG
TTGGAGGATATCATCGACCTGGTGCTTCCTCGCGGATGGTTTCCGGCGGTCGTGCCTGGAACAAAAGGTGTGACGCTAGG
CGGTATGATCGCTGCCGATGTTCACGGCAAGAACCACCGAACGGGCGGAAGCTTTCGCGAATGTGTTGAGTGGATAGAGG
TCATGGGGGCAGAGGGCCTCGTTCGACGTTGCTCCCGGCATCGCGAAGCGTTGCTGTTTAATTTCACCATCGGCGGAATG
GGCCTTACGGGGGTTATTCTACGTGCAACCATCCAACTTCGCAGAGTAGAAACGGGTTGGATGCGGAGGGTCAAGGCTCC
AACGAATAGTCTTAGTTGCACATTGGAAGTGATGGAATCGCTGCGAGATCCACAATATACAGTCGCCTGGGTTGACGCTC
TCGCTCGCGGGAAGGAATTAGGGCGAGGGATTGTAATATCGGGTAGTCACCTTTCAGAAGCGGAGCTATCGCACAACGTG
TATGAAAGGTATCCACCAGCGTTAGATAAGTGCATGTCTGTGCCGCGCTGTTCGCCGCGGCTCGTGCCCTCGGCGCCTCT
AATGGGAATATTGAACGGCGTATATGCCAGAAAATCGCGGCTTCTCCCGCCCGATGATGTCGTAGACTGGGATGCCTTCT
TCTTCCCACTCGACAGGTTGCCGCGATGGAATAGACTGTATGGACGCGCTGGATTTATTCAGCATCAATGCGTAATCCCC
CTGAAAAACGCTGAGGAAGGGATACGAGAACTGTTAGGTGAGATAAGAAAGTCCAATGTAAGCGTACCTCTTGCGGTATT
GAAGAGGATGGGTGCCGAAGCCGGGCCGTTCTCGTTTCCCATGGAGGGTTATTCGATCGCGTTCGACTTTGCTGTCTCTG
GGCGAGCATTAAATTTGCTGGCGCGGCTGGATGATATCGTTATCCAGCACGGGGGGCGCATATATCTCGCCAAAGATAGT
CGCATGTCGGCAGTCGTGCTTCGGCAATGTGACTCGCGGGTCGCCCGTTTTGAGCAAGTGCGTGCGAACTGTGGTTGGGA
TCGAGTGTTCAACTCAGTGCTGTCTGAGAGGCTAAAGATCTGA

Upstream 100 bases:

>100_bases
GGTCGCAATCGATTGGTTGAGTGAGGGTGTCCGACTGCGCGCTAAGATGCGCGGGGATGCATTTCGAGGAGCTCGTTCGG
CGACGGATTGGAGGCGTTGG

Downstream 100 bases:

>100_bases
TGAAAAGGCCTGTTCTAATTCTTGGCGCGCGATCGGCTATAGGGATCGCGATCGCCCGAAGATTCGCGGAACTAGGACAC
CCTATCCAACTCGCGGCTAG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MILSGWGRYPRVDARVFAPRVETEIEQVIRSQRTLIGRGAGLAYGDCAISVGATVEMRRLAGIELFDDAAGILTAQAGVT
LEDIIDLVLPRGWFPAVVPGTKGVTLGGMIAADVHGKNHRTGGSFRECVEWIEVMGAEGLVRRCSRHREALLFNFTIGGM
GLTGVILRATIQLRRVETGWMRRVKAPTNSLSCTLEVMESLRDPQYTVAWVDALARGKELGRGIVISGSHLSEAELSHNV
YERYPPALDKCMSVPRCSPRLVPSAPLMGILNGVYARKSRLLPPDDVVDWDAFFFPLDRLPRWNRLYGRAGFIQHQCVIP
LKNAEEGIRELLGEIRKSNVSVPLAVLKRMGAEAGPFSFPMEGYSIAFDFAVSGRALNLLARLDDIVIQHGGRIYLAKDS
RMSAVVLRQCDSRVARFEQVRANCGWDRVFNSVLSERLKI

Sequences:

>Translated_440_residues
MILSGWGRYPRVDARVFAPRVETEIEQVIRSQRTLIGRGAGLAYGDCAISVGATVEMRRLAGIELFDDAAGILTAQAGVT
LEDIIDLVLPRGWFPAVVPGTKGVTLGGMIAADVHGKNHRTGGSFRECVEWIEVMGAEGLVRRCSRHREALLFNFTIGGM
GLTGVILRATIQLRRVETGWMRRVKAPTNSLSCTLEVMESLRDPQYTVAWVDALARGKELGRGIVISGSHLSEAELSHNV
YERYPPALDKCMSVPRCSPRLVPSAPLMGILNGVYARKSRLLPPDDVVDWDAFFFPLDRLPRWNRLYGRAGFIQHQCVIP
LKNAEEGIRELLGEIRKSNVSVPLAVLKRMGAEAGPFSFPMEGYSIAFDFAVSGRALNLLARLDDIVIQHGGRIYLAKDS
RMSAVVLRQCDSRVARFEQVRANCGWDRVFNSVLSERLKI
>Mature_440_residues
MILSGWGRYPRVDARVFAPRVETEIEQVIRSQRTLIGRGAGLAYGDCAISVGATVEMRRLAGIELFDDAAGILTAQAGVT
LEDIIDLVLPRGWFPAVVPGTKGVTLGGMIAADVHGKNHRTGGSFRECVEWIEVMGAEGLVRRCSRHREALLFNFTIGGM
GLTGVILRATIQLRRVETGWMRRVKAPTNSLSCTLEVMESLRDPQYTVAWVDALARGKELGRGIVISGSHLSEAELSHNV
YERYPPALDKCMSVPRCSPRLVPSAPLMGILNGVYARKSRLLPPDDVVDWDAFFFPLDRLPRWNRLYGRAGFIQHQCVIP
LKNAEEGIRELLGEIRKSNVSVPLAVLKRMGAEAGPFSFPMEGYSIAFDFAVSGRALNLLARLDDIVIQHGGRIYLAKDS
RMSAVVLRQCDSRVARFEQVRANCGWDRVFNSVLSERLKI

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48687; Mature: 48687

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSGWGRYPRVDARVFAPRVETEIEQVIRSQRTLIGRGAGLAYGDCAISVGATVEMRRL
CEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCHHHHHH
AGIELFDDAAGILTAQAGVTLEDIIDLVLPRGWFPAVVPGTKGVTLGGMIAADVHGKNHR
CCCEEECCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEECCEEEEECCCCCCC
TGGSFRECVEWIEVMGAEGLVRRCSRHREALLFNFTIGGMGLTGVILRATIQLRRVETGW
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
MRRVKAPTNSLSCTLEVMESLRDPQYTVAWVDALARGKELGRGIVISGSHLSEAELSHNV
HHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
YERYPPALDKCMSVPRCSPRLVPSAPLMGILNGVYARKSRLLPPDDVVDWDAFFFPLDRL
HHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
PRWNRLYGRAGFIQHQCVIPLKNAEEGIRELLGEIRKSNVSVPLAVLKRMGAEAGPFSFP
CCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCC
MEGYSIAFDFAVSGRALNLLARLDDIVIQHGGRIYLAKDSRMSAVVLRQCDSRVARFEQV
CCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
RANCGWDRVFNSVLSERLKI
HHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILSGWGRYPRVDARVFAPRVETEIEQVIRSQRTLIGRGAGLAYGDCAISVGATVEMRRL
CEECCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCHHHHHH
AGIELFDDAAGILTAQAGVTLEDIIDLVLPRGWFPAVVPGTKGVTLGGMIAADVHGKNHR
CCCEEECCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCEECCEEEEECCCCCCC
TGGSFRECVEWIEVMGAEGLVRRCSRHREALLFNFTIGGMGLTGVILRATIQLRRVETGW
CCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
MRRVKAPTNSLSCTLEVMESLRDPQYTVAWVDALARGKELGRGIVISGSHLSEAELSHNV
HHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHH
YERYPPALDKCMSVPRCSPRLVPSAPLMGILNGVYARKSRLLPPDDVVDWDAFFFPLDRL
HHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
PRWNRLYGRAGFIQHQCVIPLKNAEEGIRELLGEIRKSNVSVPLAVLKRMGAEAGPFSFP
CCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCC
MEGYSIAFDFAVSGRALNLLARLDDIVIQHGGRIYLAKDSRMSAVVLRQCDSRVARFEQV
CCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
RANCGWDRVFNSVLSERLKI
HHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]