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The map label for this gene is pgl [H]

Identifier: 158425254

GI number: 158425254

Start: 4167614

End: 4168339

Strand: Direct

Name: pgl [H]

Synonym: AZC_3630

Alternate gene names: 158425254

Gene position: 4167614-4168339 (Clockwise)

Preceding gene: 158425253

Following gene: 158425255

Centisome position: 77.61

GC content: 73.55

Gene sequence:

>726_bases
ATGACCGAAACCGCACCGGGCGAGCTGCTGCCCGTCGCCTTCACGGCCTATGAGGATCGCGCGGCGCTCGCCCGCGCCCT
CGCAGCCCACGTGGCCGAGGCCCTACGCCGGCGCCTCGCCACCGATGGCCGCGCCGCGCTCGCCGTCTCCGGCGGGCGCA
CGCCCACCCTCTTCTTCGAGACGCTCTCCGGCGCTCCGCTCGACTGGGCGAAGGTGAGCGTGACGCTGGTGGACGAGCGC
TGGGTGCCTGAGACTTCGGACCGCTCCAACGCCGCTCTCGTGCGCGCCCACTTGCTGCGTGGCCCCGCCACCGCCGCCCG
CTTTGTGCCGCTCTATACCGGGGCCCCCACCCCTGAGGAGGGGCTCACCGCCGCCCATGCGGCCATCGCCGATCTCCCCC
AGCCCTTCGCCGCCGTGGTGCTGGGCATGGGCGACGACGCCCACACCGCCTCCTTCTTTCCCGGCGCGGACACGCTGGCC
ACCGCTATCGATCCGCGCACCGATGCCAAGCTCATCACCGCCCGCGCGCCGGCGGCGGGGGAGCCGCGCATCACCTTCAC
CATCGGCCCGCTGATCGGCGCGGACGCCCTGTTCCTGCACATCGAGGGGGCCGGCAAGAAAGCCGTGCTCGATGCGGCGC
GGGAACCCGGCGACCCCATGGAGCGTCCGATCCGCGCCATCCTGCTGCACAGCCCACGCCCGCTCGACGTGCTGTGGTGC
CCCTGA

Upstream 100 bases:

>100_bases
GCGCGACGGCCGCACCTGGATGGACGACTGACGCCTGCCGCGTGACCCCGGCTCCGGCCGGGGACCGCCCTGCCCTTCCG
GCCCCGCACTGGAGCCCGCC

Downstream 100 bases:

>100_bases
CGGAGATCCTTCCATGACCGACGTGACCACCGAGATCGCGGACCCGCAGGCGCGTGCCGAGGCGGTCTCCGCGGCCTGGG
AGCGCCTCGCCGCCCTGCGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTETAPGELLPVAFTAYEDRAALARALAAHVAEALRRRLATDGRAALAVSGGRTPTLFFETLSGAPLDWAKVSVTLVDER
WVPETSDRSNAALVRAHLLRGPATAARFVPLYTGAPTPEEGLTAAHAAIADLPQPFAAVVLGMGDDAHTASFFPGADTLA
TAIDPRTDAKLITARAPAAGEPRITFTIGPLIGADALFLHIEGAGKKAVLDAAREPGDPMERPIRAILLHSPRPLDVLWC
P

Sequences:

>Translated_241_residues
MTETAPGELLPVAFTAYEDRAALARALAAHVAEALRRRLATDGRAALAVSGGRTPTLFFETLSGAPLDWAKVSVTLVDER
WVPETSDRSNAALVRAHLLRGPATAARFVPLYTGAPTPEEGLTAAHAAIADLPQPFAAVVLGMGDDAHTASFFPGADTLA
TAIDPRTDAKLITARAPAAGEPRITFTIGPLIGADALFLHIEGAGKKAVLDAAREPGDPMERPIRAILLHSPRPLDVLWC
P
>Mature_240_residues
TETAPGELLPVAFTAYEDRAALARALAAHVAEALRRRLATDGRAALAVSGGRTPTLFFETLSGAPLDWAKVSVTLVDERW
VPETSDRSNAALVRAHLLRGPATAARFVPLYTGAPTPEEGLTAAHAAIADLPQPFAAVVLGMGDDAHTASFFPGADTLAT
AIDPRTDAKLITARAPAAGEPRITFTIGPLIGADALFLHIEGAGKKAVLDAAREPGDPMERPIRAILLHSPRPLDVLWCP

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6321687, Length=219, Percent_Identity=25.5707762557078, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321957, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25300; Mature: 25169

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETAPGELLPVAFTAYEDRAALARALAAHVAEALRRRLATDGRAALAVSGGRTPTLFFE
CCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
TLSGAPLDWAKVSVTLVDERWVPETSDRSNAALVRAHLLRGPATAARFVPLYTGAPTPEE
ECCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHEEEEEECCCCCCHH
GLTAAHAAIADLPQPFAAVVLGMGDDAHTASFFPGADTLATAIDPRTDAKLITARAPAAG
HHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCC
EPRITFTIGPLIGADALFLHIEGAGKKAVLDAAREPGDPMERPIRAILLHSPRPLDVLWC
CCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHEEECCCCCCEEEEC
P
C
>Mature Secondary Structure 
TETAPGELLPVAFTAYEDRAALARALAAHVAEALRRRLATDGRAALAVSGGRTPTLFFE
CCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
TLSGAPLDWAKVSVTLVDERWVPETSDRSNAALVRAHLLRGPATAARFVPLYTGAPTPEE
ECCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHHEEEEEECCCCCCHH
GLTAAHAAIADLPQPFAAVVLGMGDDAHTASFFPGADTLATAIDPRTDAKLITARAPAAG
HHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCC
EPRITFTIGPLIGADALFLHIEGAGKKAVLDAAREPGDPMERPIRAILLHSPRPLDVLWC
CCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHEEECCCCCCEEEEC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]