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The map label for this gene is pgi [H]

Identifier: 158425255

GI number: 158425255

Start: 4168353

End: 4170035

Strand: Direct

Name: pgi [H]

Synonym: AZC_3631

Alternate gene names: 158425255

Gene position: 4168353-4170035 (Clockwise)

Preceding gene: 158425254

Following gene: 158425256

Centisome position: 77.63

GC content: 69.1

Gene sequence:

>1683_bases
ATGACCGACGTGACCACCGAGATCGCGGACCCGCAGGCGCGTGCCGAGGCGGTCTCCGCGGCCTGGGAGCGCCTCGCCGC
CCTGCGCGCCGCGACGAGCGATACCCCCATCGCCCGGCTTTTCGACGCGCCGAACCGCTTCGAGCATTTCTCGCTCAGCC
TCGGCGACCTGCTGCTCGATGCCTCCAAGACCTCGCTGACCGAGGAGGCGCTGGCTGGCCTCTACGCACTCATGCGCGCG
GCTGGCGTGGAGGCGCGGCGGGACGCCATGTTCGCCGGCGCCCACATCAACATCACCGAGGACCGGGCCGTGCTCCACAC
GGCGCTGCGCGACACCACCGCCGCGCCGCTGCTGGTGGACGGGCAGGATGTGAAGCCGGAAATCCGCGAGACGCTGGGCC
GCCTCGCCGCCTTCGCCGAGGGCGTGCGCAAGGGCACCATCGCCGGGGCCCGCGGCCAGGCCTTCACGGACGTGGTCAAT
ATCGGCATCGGCGGCTCCGACCTCGGCCCGGTGATGGCGACGCTGGCGCTCGCCCCCTATCACGATGGCCCGCGCCTGCA
CTTCGTCTCGAACGTCGACGGCGCGCACATCCATGACGTGCTGAAGCCGCTCAATCCCGCCACCACGCTCATCATCATCG
CCTCCAAGACCTTCACCACCATCGAGACCATGACCAACGCCCGCACGGCGCGGGCCTGGATCGCCGATGCGCAGGGCGAG
GCGGCGGTGGGCGCGCATTTTGCCGCCGTCTCCACCGCCCTCGACAAGGTGGCCGCCTTCGGCATCGACACCGCCCGCGC
CTTTGGCTTCTGGGATTGGGTGGGCGGGCGCTATTCGGTGTGGTCGGCGGTGGGGCTCCCGCTCATGGTCGCCATCGGCC
CGGCCCTGTTCGCGGATTTCCTCGCCGGCGGCGCGGCCATCGACGAGCACTTCCGCAATGCGCCGCTGGAGGAGAATCTC
CCTGCCCTGCTGGCCGCTGTCGGCCTGTGGCACCGGAACGTGTGCGGCTATCCGACCCGCGCCGTCATTCCCTATGACCA
GCGCCTCGCCCGCCTGCCCGCCTATCTCCAGCAGCTCGACATGGAGAGCAACGGCAAGTCGGTGACCCTCGACGGCACGC
CGGTGGCGCGACCCACGGGGCCTGTGGTCTGGGGCGAGCCGGGCACCAATTCCCAGCACGCCTTCTTCCAGCTCATCCAC
CAGGGCACGGACATCATCCCGGTGGAGTTCCTGATTGCCGCTCAGGGCCACGAGCCGAAGCTGCGCCACCAGCACGATCT
GCTGATCGCCAACTGCCTTGCCCAGTCGGAAGCCCTGCTGAGGGGTCGCTCGCTGGAGGCGGCAACCGCGCAGCTCCGCG
CCAAGGGCATGGGTGAGGCGGAGGCACAACGTATTGCACCGCACCGTGTTTTCTCCGGCAGCCGGCCGTCCCTCACCCTC
GCTTATACGCTCCTCGACCCCTTCACCCTGGGTCGCCTCATCGCGCTCTATGAGCACCGCGTCTTCATAGAGGCCGCAGT
GTGGGGCATAGACGCCTTCGATCAATGGGGTGTGGAACTCGGCAAGGAGCTGGCGACGGACTTCCTGCCCGCCGTGACAG
AGGGCGCCGTGCCTCCCGGAACGTCCGGATCGACGCGCGGCACTCTTTCGCACCTGCGAAATCTTGCCGCTGACGCAAAG
TAA

Upstream 100 bases:

>100_bases
CGGGAACCCGGCGACCCCATGGAGCGTCCGATCCGCGCCATCCTGCTGCACAGCCCACGCCCGCTCGACGTGCTGTGGTG
CCCCTGACGGAGATCCTTCC

Downstream 100 bases:

>100_bases
TTGGTATGCGCAAACGCGGGAGCGTCCTGCGTTATTTTGTATACCACGGATCCTGAAACTGGGTCAGTATGTCTTCCGTG
AACGACGGCCGCCGACGTGG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MTDVTTEIADPQARAEAVSAAWERLAALRAATSDTPIARLFDAPNRFEHFSLSLGDLLLDASKTSLTEEALAGLYALMRA
AGVEARRDAMFAGAHINITEDRAVLHTALRDTTAAPLLVDGQDVKPEIRETLGRLAAFAEGVRKGTIAGARGQAFTDVVN
IGIGGSDLGPVMATLALAPYHDGPRLHFVSNVDGAHIHDVLKPLNPATTLIIIASKTFTTIETMTNARTARAWIADAQGE
AAVGAHFAAVSTALDKVAAFGIDTARAFGFWDWVGGRYSVWSAVGLPLMVAIGPALFADFLAGGAAIDEHFRNAPLEENL
PALLAAVGLWHRNVCGYPTRAVIPYDQRLARLPAYLQQLDMESNGKSVTLDGTPVARPTGPVVWGEPGTNSQHAFFQLIH
QGTDIIPVEFLIAAQGHEPKLRHQHDLLIANCLAQSEALLRGRSLEAATAQLRAKGMGEAEAQRIAPHRVFSGSRPSLTL
AYTLLDPFTLGRLIALYEHRVFIEAAVWGIDAFDQWGVELGKELATDFLPAVTEGAVPPGTSGSTRGTLSHLRNLAADAK

Sequences:

>Translated_560_residues
MTDVTTEIADPQARAEAVSAAWERLAALRAATSDTPIARLFDAPNRFEHFSLSLGDLLLDASKTSLTEEALAGLYALMRA
AGVEARRDAMFAGAHINITEDRAVLHTALRDTTAAPLLVDGQDVKPEIRETLGRLAAFAEGVRKGTIAGARGQAFTDVVN
IGIGGSDLGPVMATLALAPYHDGPRLHFVSNVDGAHIHDVLKPLNPATTLIIIASKTFTTIETMTNARTARAWIADAQGE
AAVGAHFAAVSTALDKVAAFGIDTARAFGFWDWVGGRYSVWSAVGLPLMVAIGPALFADFLAGGAAIDEHFRNAPLEENL
PALLAAVGLWHRNVCGYPTRAVIPYDQRLARLPAYLQQLDMESNGKSVTLDGTPVARPTGPVVWGEPGTNSQHAFFQLIH
QGTDIIPVEFLIAAQGHEPKLRHQHDLLIANCLAQSEALLRGRSLEAATAQLRAKGMGEAEAQRIAPHRVFSGSRPSLTL
AYTLLDPFTLGRLIALYEHRVFIEAAVWGIDAFDQWGVELGKELATDFLPAVTEGAVPPGTSGSTRGTLSHLRNLAADAK
>Mature_559_residues
TDVTTEIADPQARAEAVSAAWERLAALRAATSDTPIARLFDAPNRFEHFSLSLGDLLLDASKTSLTEEALAGLYALMRAA
GVEARRDAMFAGAHINITEDRAVLHTALRDTTAAPLLVDGQDVKPEIRETLGRLAAFAEGVRKGTIAGARGQAFTDVVNI
GIGGSDLGPVMATLALAPYHDGPRLHFVSNVDGAHIHDVLKPLNPATTLIIIASKTFTTIETMTNARTARAWIADAQGEA
AVGAHFAAVSTALDKVAAFGIDTARAFGFWDWVGGRYSVWSAVGLPLMVAIGPALFADFLAGGAAIDEHFRNAPLEENLP
ALLAAVGLWHRNVCGYPTRAVIPYDQRLARLPAYLQQLDMESNGKSVTLDGTPVARPTGPVVWGEPGTNSQHAFFQLIHQ
GTDIIPVEFLIAAQGHEPKLRHQHDLLIANCLAQSEALLRGRSLEAATAQLRAKGMGEAEAQRIAPHRVFSGSRPSLTLA
YTLLDPFTLGRLIALYEHRVFIEAAVWGIDAFDQWGVELGKELATDFLPAVTEGAVPPGTSGSTRGTLSHLRNLAADAK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=533, Percent_Identity=50.656660412758, Blast_Score=551, Evalue=1e-157,
Organism=Homo sapiens, GI296080693, Length=533, Percent_Identity=47.4671669793621, Blast_Score=503, Evalue=1e-142,
Organism=Escherichia coli, GI1790457, Length=538, Percent_Identity=48.6988847583643, Blast_Score=527, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI71996708, Length=538, Percent_Identity=48.1412639405204, Blast_Score=527, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI71996703, Length=538, Percent_Identity=48.1412639405204, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6319673, Length=543, Percent_Identity=46.4088397790055, Blast_Score=483, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24651916, Length=544, Percent_Identity=48.1617647058824, Blast_Score=525, Evalue=1e-149,
Organism=Drosophila melanogaster, GI24651914, Length=544, Percent_Identity=48.1617647058824, Blast_Score=525, Evalue=1e-149,
Organism=Drosophila melanogaster, GI17737445, Length=544, Percent_Identity=48.1617647058824, Blast_Score=525, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59742; Mature: 59610

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVTTEIADPQARAEAVSAAWERLAALRAATSDTPIARLFDAPNRFEHFSLSLGDLLLD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHEHEEEHHHHHHC
ASKTSLTEEALAGLYALMRAAGVEARRDAMFAGAHINITEDRAVLHTALRDTTAAPLLVD
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCEEEECCCHHHHHHHHHHCCCCCEEEC
GQDVKPEIRETLGRLAAFAEGVRKGTIAGARGQAFTDVVNIGIGGSDLGPVMATLALAPY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCCCHHHHHHHHHHCCC
HDGPRLHFVSNVDGAHIHDVLKPLNPATTLIIIASKTFTTIETMTNARTARAWIADAQGE
CCCCCEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHEECCCCC
AAVGAHFAAVSTALDKVAAFGIDTARAFGFWDWVGGRYSVWSAVGLPLMVAIGPALFADF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHH
LAGGAAIDEHFRNAPLEENLPALLAAVGLWHRNVCGYPTRAVIPYDQRLARLPAYLQQLD
HHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHC
MESNGKSVTLDGTPVARPTGPVVWGEPGTNSQHAFFQLIHQGTDIIPVEFLIAAQGHEPK
CCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCC
LRHQHDLLIANCLAQSEALLRGRSLEAATAQLRAKGMGEAEAQRIAPHRVFSGSRPSLTL
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCCEEE
AYTLLDPFTLGRLIALYEHRVFIEAAVWGIDAFDQWGVELGKELATDFLPAVTEGAVPPG
EEEHHCHHHHHHHHHHHHHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TSGSTRGTLSHLRNLAADAK
CCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDVTTEIADPQARAEAVSAAWERLAALRAATSDTPIARLFDAPNRFEHFSLSLGDLLLD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHEHEEEHHHHHHC
ASKTSLTEEALAGLYALMRAAGVEARRDAMFAGAHINITEDRAVLHTALRDTTAAPLLVD
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHEEECCEEEECCCHHHHHHHHHHCCCCCEEEC
GQDVKPEIRETLGRLAAFAEGVRKGTIAGARGQAFTDVVNIGIGGSDLGPVMATLALAPY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCCCHHHHHHHHHHCCC
HDGPRLHFVSNVDGAHIHDVLKPLNPATTLIIIASKTFTTIETMTNARTARAWIADAQGE
CCCCCEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHEECCCCC
AAVGAHFAAVSTALDKVAAFGIDTARAFGFWDWVGGRYSVWSAVGLPLMVAIGPALFADF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHH
LAGGAAIDEHFRNAPLEENLPALLAAVGLWHRNVCGYPTRAVIPYDQRLARLPAYLQQLD
HHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHC
MESNGKSVTLDGTPVARPTGPVVWGEPGTNSQHAFFQLIHQGTDIIPVEFLIAAQGHEPK
CCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCC
LRHQHDLLIANCLAQSEALLRGRSLEAATAQLRAKGMGEAEAQRIAPHRVFSGSRPSLTL
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCCCHHHCCCCCCCEEE
AYTLLDPFTLGRLIALYEHRVFIEAAVWGIDAFDQWGVELGKELATDFLPAVTEGAVPPG
EEEHHCHHHHHHHHHHHHHHHEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TSGSTRGTLSHLRNLAADAK
CCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA