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The map label for this gene is trkH [H]

Identifier: 158424705

GI number: 158424705

Start: 3522548

End: 3523954

Strand: Reverse

Name: trkH [H]

Synonym: AZC_3081

Alternate gene names: 158424705

Gene position: 3523954-3522548 (Counterclockwise)

Preceding gene: 158424706

Following gene: 158424704

Centisome position: 65.63

GC content: 72.71

Gene sequence:

>1407_bases
ATGGCCCCCATTCTCCGCCTGTTCGCCCTGGTGCTGGCGCTGCTCGCCGCGGCGGCGCTCGTGCCGGCGCTGGTGGGCCT
CGGCGCGCGGGACGGATCTGCGCCCGTCTTCATCGCCACGGCCGTGGCGAGCCTGTTCCTGGCGGGTGCGGTGCATCTGG
CGGTGCGCGGGCGGCCGGGCCGGCTGCGGCGGCTGCATCTGTTCGCCGCGCTCGGCGTGCTCTGGCTGCTGGTTCCGATC
ATGGCGGCCCCCGCCGTGGCCGTGCTGGCGCCCATGGCTTTCGGCGGGGCGGTGCTGGAGGCACTGTCCGCCTTCACGAC
CACCGGCCTGTCGTCCGTGGGCGAGGCGCCGGCCAGCCTCCATGTCTGGCTCGCCCTGCTGCAATGGGCCGGCGGGCTGC
TGACCCTGGTGGCCGGCATCGCCGTGCTGGCCCCCGCCGGGGTAGCGGGCCTGCCGGACCGGGCGGTTCATCCGGGGGAG
ACGGTGGAAGCCATCGATCTGCTGGATGCGCTCGGCACCGTGGCGCCCATCTATGGCCTCGCGACCCTCGTTGCCTTCAT
TGCGATGCTGGGCGCGGGGGCCTCGCTCCTCTCCGCCGCGACGCTCGCCACCGCCGTCATCTCCACCGGCGCGCACGTGC
CGCCGGAGGTGCATGAATTCCTGGCGGCCAGCGTGCCGGGCCGGTGGGTGACCATTCCCTTCCTGCTCTGGTCTGCCACC
AGCGTGCGCTGGCACAAGGCCCTGGTGTCCCGGCGCATCCACGCGGCCCCCGAGCAGGGCGAGAGCCTGATCCTGTTCGG
CTACTGGGCGGTGTTCGGCCTCGTCATGGGCGCCTATTTCTTCCGGGGCGCCGCCGGCCTCCACACCCATGAAGCGGTGC
TCGACGGGCTGTTCGGCGCGGCCTCGCTGATCTCCACCACCGGGCTTGCGCCCCACCGGGGGGCCTTCGACGAACTGCCG
CCGGCTCTGGTCCTTGCCGTGGCCTTCGTGGGCGGCGGGGCGCTGTCGGTCTCGGGCGGCCTGAAGATCCTGCGCGTGCG
GGCCATGCTGCTGCGGGCGCGGGGCGATCTGATGCGGCTGGTCTATCCCAATCTCGTCCAGCCCTCGCGCACCGGAGAGG
GCGGAGTCGGCTCGGCCATGCGCGGCGTGTGGGTGGGCATGGTCGCCCTCTGCCTGACCTTTGCCGCAGCGCTCATCCTC
ATCGCGGGCAGCATGCCGAGCTTCGAGGCGGCGGTGTCCACGGCGGTGTCCGCTTTGAGCAATACGGGGCCGCTGCTCGA
CGGCACGCCGGGGCCGGAGGACTTCGACCTGCTGGCAGCGGTCGGGGCCGGTTTCGCGATGATCGCCGGACGGCTGGAGA
CGGTCGGTGCCTTCGTCATCATCCACCTCGCCTTCTGGCGGACCTGA

Upstream 100 bases:

>100_bases
GCGGGCGCAGGACCGTGTGGTGCTGTTCGCATTGGCCGACGACATCAAGCGTGTGGAGCAGCTCTTCCGCGTCAGCCTCG
AATTCTTCTGAGCCCTCCCG

Downstream 100 bases:

>100_bases
CCGCAACGCCGTCGGGCACATGCCGCGCTTGTGATCGCGGCGTAAACCGGGGGCTCAGCCGGCAGCGCCCTTGAGCGTCA
CAGCGTGCGCAAGGCCATGC

Product: Trk-type K+ transporters membrane component

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MAPILRLFALVLALLAAAALVPALVGLGARDGSAPVFIATAVASLFLAGAVHLAVRGRPGRLRRLHLFAALGVLWLLVPI
MAAPAVAVLAPMAFGGAVLEALSAFTTTGLSSVGEAPASLHVWLALLQWAGGLLTLVAGIAVLAPAGVAGLPDRAVHPGE
TVEAIDLLDALGTVAPIYGLATLVAFIAMLGAGASLLSAATLATAVISTGAHVPPEVHEFLAASVPGRWVTIPFLLWSAT
SVRWHKALVSRRIHAAPEQGESLILFGYWAVFGLVMGAYFFRGAAGLHTHEAVLDGLFGAASLISTTGLAPHRGAFDELP
PALVLAVAFVGGGALSVSGGLKILRVRAMLLRARGDLMRLVYPNLVQPSRTGEGGVGSAMRGVWVGMVALCLTFAAALIL
IAGSMPSFEAAVSTAVSALSNTGPLLDGTPGPEDFDLLAAVGAGFAMIAGRLETVGAFVIIHLAFWRT

Sequences:

>Translated_468_residues
MAPILRLFALVLALLAAAALVPALVGLGARDGSAPVFIATAVASLFLAGAVHLAVRGRPGRLRRLHLFAALGVLWLLVPI
MAAPAVAVLAPMAFGGAVLEALSAFTTTGLSSVGEAPASLHVWLALLQWAGGLLTLVAGIAVLAPAGVAGLPDRAVHPGE
TVEAIDLLDALGTVAPIYGLATLVAFIAMLGAGASLLSAATLATAVISTGAHVPPEVHEFLAASVPGRWVTIPFLLWSAT
SVRWHKALVSRRIHAAPEQGESLILFGYWAVFGLVMGAYFFRGAAGLHTHEAVLDGLFGAASLISTTGLAPHRGAFDELP
PALVLAVAFVGGGALSVSGGLKILRVRAMLLRARGDLMRLVYPNLVQPSRTGEGGVGSAMRGVWVGMVALCLTFAAALIL
IAGSMPSFEAAVSTAVSALSNTGPLLDGTPGPEDFDLLAAVGAGFAMIAGRLETVGAFVIIHLAFWRT
>Mature_467_residues
APILRLFALVLALLAAAALVPALVGLGARDGSAPVFIATAVASLFLAGAVHLAVRGRPGRLRRLHLFAALGVLWLLVPIM
AAPAVAVLAPMAFGGAVLEALSAFTTTGLSSVGEAPASLHVWLALLQWAGGLLTLVAGIAVLAPAGVAGLPDRAVHPGET
VEAIDLLDALGTVAPIYGLATLVAFIAMLGAGASLLSAATLATAVISTGAHVPPEVHEFLAASVPGRWVTIPFLLWSATS
VRWHKALVSRRIHAAPEQGESLILFGYWAVFGLVMGAYFFRGAAGLHTHEAVLDGLFGAASLISTTGLAPHRGAFDELPP
ALVLAVAFVGGGALSVSGGLKILRVRAMLLRARGDLMRLVYPNLVQPSRTGEGGVGSAMRGVWVGMVALCLTFAAALILI
AGSMPSFEAAVSTAVSALSNTGPLLDGTPGPEDFDLLAAVGAGFAMIAGRLETVGAFVIIHLAFWRT

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=498, Percent_Identity=26.3052208835341, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787626, Length=476, Percent_Identity=23.7394957983193, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 47686; Mature: 47555

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPILRLFALVLALLAAAALVPALVGLGARDGSAPVFIATAVASLFLAGAVHLAVRGRPG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCC
RLRRLHLFAALGVLWLLVPIMAAPAVAVLAPMAFGGAVLEALSAFTTTGLSSVGEAPASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
HVWLALLQWAGGLLTLVAGIAVLAPAGVAGLPDRAVHPGETVEAIDLLDALGTVAPIYGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATLVAFIAMLGAGASLLSAATLATAVISTGAHVPPEVHEFLAASVPGRWVTIPFLLWSAT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHCC
SVRWHKALVSRRIHAAPEQGESLILFGYWAVFGLVMGAYFFRGAAGLHTHEAVLDGLFGA
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASLISTTGLAPHRGAFDELPPALVLAVAFVGGGALSVSGGLKILRVRAMLLRARGDLMRL
HHHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
VYPNLVQPSRTGEGGVGSAMRGVWVGMVALCLTFAAALILIAGSMPSFEAAVSTAVSALS
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
NTGPLLDGTPGPEDFDLLAAVGAGFAMIAGRLETVGAFVIIHLAFWRT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
APILRLFALVLALLAAAALVPALVGLGARDGSAPVFIATAVASLFLAGAVHLAVRGRPG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCC
RLRRLHLFAALGVLWLLVPIMAAPAVAVLAPMAFGGAVLEALSAFTTTGLSSVGEAPASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
HVWLALLQWAGGLLTLVAGIAVLAPAGVAGLPDRAVHPGETVEAIDLLDALGTVAPIYGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATLVAFIAMLGAGASLLSAATLATAVISTGAHVPPEVHEFLAASVPGRWVTIPFLLWSAT
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHCC
SVRWHKALVSRRIHAAPEQGESLILFGYWAVFGLVMGAYFFRGAAGLHTHEAVLDGLFGA
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASLISTTGLAPHRGAFDELPPALVLAVAFVGGGALSVSGGLKILRVRAMLLRARGDLMRL
HHHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
VYPNLVQPSRTGEGGVGSAMRGVWVGMVALCLTFAAALILIAGSMPSFEAAVSTAVSALS
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
NTGPLLDGTPGPEDFDLLAAVGAGFAMIAGRLETVGAFVIIHLAFWRT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]