Click here to switch to the map view.

The map label for this gene is hfq

Identifier: 158424704

GI number: 158424704

Start: 3521987

End: 3522244

Strand: Reverse

Name: hfq

Synonym: AZC_3080

Alternate gene names: 158424704

Gene position: 3522244-3521987 (Counterclockwise)

Preceding gene: 158424705

Following gene: 158424703

Centisome position: 65.59

GC content: 58.91

Gene sequence:

>258_bases
ATGGCGGCGGAACGCACACAAAACCTGCAAGACACCTTTCTCAACCACGTCCGCAAGAGCAAGACGCCCCTCACCATCTT
CCTGGTGAATGGCGTGAAGCTCCAGGGCGTCGTGACCTGGTTCGACAACTTCTGCGTGCTCCTGCGTCGCGACGGGCACT
CGCAATTGGTCTACAAGCACGCTATCTCCACGATCATGCCCGGGCATCCGGTGCAACTGTTTGATCCCACCGACGAGGTG
GCTTCGGAGAAAGCGTGA

Upstream 100 bases:

>100_bases
CTAGCGCCGGAATTCCTGTTTGCGCATCGTCTTGCCTTGCCCTTGCGGCATCGCGACCGTGTGACATGACGGGGCAACGC
CGAAAGAAACGGATACGAAA

Downstream 100 bases:

>100_bases
TCCGGCGTGGAGCTTAAGGGACCGCGGGGCGCAGCGGGGGGTGGACTGAAGGGCGTGGACCGTCACGCTCCGCCCACCCG
TTGTGCCGTCATTACCCCAC

Product: protein hfq

Products: NA

Alternate protein names: Nif-regulating factor

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDEV
ASEKA

Sequences:

>Translated_85_residues
MAAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDEV
ASEKA
>Mature_84_residues
AAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDEVA
SEKA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Seems to

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=53.7313432835821, Blast_Score=81, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_AZOC5 (Q43971)

Other databases:

- EMBL:   X76450
- EMBL:   AP009384
- PIR:   I39519
- RefSeq:   YP_001525996.1
- ProteinModelPortal:   Q43971
- SMR:   Q43971
- GeneID:   5691901
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_3080
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- BioCyc:   ACAU438753:AZC_3080-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9621; Mature: 9490

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKH
CCCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEHHHHHHHCEEEEEECCCCCHHHHHH
AISTIMPGHPVQLFDPTDEVASEKA
HHHHCCCCCCEEEECCCHHHCCCCC
>Mature Secondary Structure 
AAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKH
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCEEEEHHHHHHHCEEEEEECCCCCHHHHHH
AISTIMPGHPVQLFDPTDEVASEKA
HHHHCCCCCCEEEECCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8197116