Click here to switch to the map view.

The map label for this gene is trkA

Identifier: 158424706

GI number: 158424706

Start: 3523964

End: 3525340

Strand: Reverse

Name: trkA

Synonym: AZC_3082

Alternate gene names: 158424706

Gene position: 3525340-3523964 (Counterclockwise)

Preceding gene: 158424707

Following gene: 158424705

Centisome position: 65.65

GC content: 67.9

Gene sequence:

>1377_bases
ATGAAGGTCGTGATCTGCGGGGCAGGGCAGGTGGGGTTCGGCATTGCCGAGCGCCTCGCCAGCGAGCAGAACGACGTCTC
CATCGTCGATGCGAGCCCGCGCCGGATCCAGATCGCCACCGACCAGCTCGACGTGCGCGGCGTGGTGGGCCATGGCTCCC
ATCCGGACGTGCTGGCCCGTGCCGGCATCGAGCAGGCGGACATGCTGATCGCGGTCACCCTGCATGACGAAGTGAACATG
GTGGCCTGCCAGGTGGGCCATTCGCTGTTCAACGTGCCGACCAAGGTCGCCCGCATCCGCGCCCAGACCTATCTGCAGCC
CGAATGGCGCAGCATGCTCTCCCGCGACCATATGCCCATCGACGTGGTGATTTCACCGGAGATCGAGGTGGGCGAGATGG
TGCTGCGGCGCCTCTCGCTGCCGGGGGCGGTGGATACGGTCTCCTTCGGCGACGGCTCGGTGGTGATCGCCGGCGTGCTG
TGCGGCGAGGCCTGCCCGGTGGTCGACACCCCGCTCACCCAGCTCACCCAGCTCTTCCCCGACCTGCCGGCGACCATCGT
TGCCATCAACCGCAACGGCAAGGTGATGGCGACCCGCTCGTCGGACCAGATCCAGACCGGGGACATCGCCTATTTCGTCG
CTCCCGCCGATCAGGTGGGGCGCACGCTCTCCATCTTCGGCCACGACGAAATCCCGGCCAAGCGCATCATCATCGGCGGC
GGCGGCAACATCGGCCTCTACGTGGCGCAGGAGCTGGAGAAGCGGAACGCGGCCGCGCGCATCAAGGTGGTGGAGAGCAA
TCGCGAGCGGGCGCAGGCCATCGCGGAGGGGCTGTCGCGCTCGGTGGTGCTCCATGGCGACTCGCTCGCACGCGAGATCC
TCGACGAGGCCGGGGTCGCCGACAGCGACACCATGATCGCCCTCACCAATGACGACCGCGTCAACATCCTCTCCTGCCTG
CTCGCCAAGCAACTCGGCGCCCAGCGCATCCTCGCCTTGGTGAACGAGCAGGGCTATGCGGGCTTTGCCCACGGGCTCGG
CATCGACGCCTACGTCAATCCGCGCCAGATCACCGTCTCCAAGGTGCTCCAGCACGTGCGGCGCGGCCGCATCCGGGGCG
TGCACTCGCTGCTGGACGGGGCCGGCGAGATGATCGAGGCGGAGGCGCTCGAGACCTCACCGCTGGTGGGCCGCCCGCTA
CGCGACATCGACCTGCTCAAGGGCATGCGCATCGGCGCGGTGGTGCGCAACGGCGTCGTCATGCGCCCGAGCGGCGATAC
GGTTGTGCGGGCGCAGGACCGTGTGGTGCTGTTCGCATTGGCCGACGACATCAAGCGTGTGGAGCAGCTCTTCCGCGTCA
GCCTCGAATTCTTCTGA

Upstream 100 bases:

>100_bases
TTCGCGGCGGCGCGGTGTTGCAGGGGCGGCAGCCGCGCCGGGAAAACGGGATCGGCATTCGGGCCAAGGGCTTGCGGGTG
TCAGGCGGCGGGGGGTGGTC

Downstream 100 bases:

>100_bases
GCCCTCCCGATGGCCCCCATTCTCCGCCTGTTCGCCCTGGTGCTGGCGCTGCTCGCCGCGGCGGCGCTCGTGCCGGCGCT
GGTGGGCCTCGGCGCGCGGG

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVVICGAGQVGFGIAERLASEQNDVSIVDASPRRIQIATDQLDVRGVVGHGSHPDVLARAGIEQADMLIAVTLHDEVNM
VACQVGHSLFNVPTKVARIRAQTYLQPEWRSMLSRDHMPIDVVISPEIEVGEMVLRRLSLPGAVDTVSFGDGSVVIAGVL
CGEACPVVDTPLTQLTQLFPDLPATIVAINRNGKVMATRSSDQIQTGDIAYFVAPADQVGRTLSIFGHDEIPAKRIIIGG
GGNIGLYVAQELEKRNAAARIKVVESNRERAQAIAEGLSRSVVLHGDSLAREILDEAGVADSDTMIALTNDDRVNILSCL
LAKQLGAQRILALVNEQGYAGFAHGLGIDAYVNPRQITVSKVLQHVRRGRIRGVHSLLDGAGEMIEAEALETSPLVGRPL
RDIDLLKGMRIGAVVRNGVVMRPSGDTVVRAQDRVVLFALADDIKRVEQLFRVSLEFF

Sequences:

>Translated_458_residues
MKVVICGAGQVGFGIAERLASEQNDVSIVDASPRRIQIATDQLDVRGVVGHGSHPDVLARAGIEQADMLIAVTLHDEVNM
VACQVGHSLFNVPTKVARIRAQTYLQPEWRSMLSRDHMPIDVVISPEIEVGEMVLRRLSLPGAVDTVSFGDGSVVIAGVL
CGEACPVVDTPLTQLTQLFPDLPATIVAINRNGKVMATRSSDQIQTGDIAYFVAPADQVGRTLSIFGHDEIPAKRIIIGG
GGNIGLYVAQELEKRNAAARIKVVESNRERAQAIAEGLSRSVVLHGDSLAREILDEAGVADSDTMIALTNDDRVNILSCL
LAKQLGAQRILALVNEQGYAGFAHGLGIDAYVNPRQITVSKVLQHVRRGRIRGVHSLLDGAGEMIEAEALETSPLVGRPL
RDIDLLKGMRIGAVVRNGVVMRPSGDTVVRAQDRVVLFALADDIKRVEQLFRVSLEFF
>Mature_458_residues
MKVVICGAGQVGFGIAERLASEQNDVSIVDASPRRIQIATDQLDVRGVVGHGSHPDVLARAGIEQADMLIAVTLHDEVNM
VACQVGHSLFNVPTKVARIRAQTYLQPEWRSMLSRDHMPIDVVISPEIEVGEMVLRRLSLPGAVDTVSFGDGSVVIAGVL
CGEACPVVDTPLTQLTQLFPDLPATIVAINRNGKVMATRSSDQIQTGDIAYFVAPADQVGRTLSIFGHDEIPAKRIIIGG
GGNIGLYVAQELEKRNAAARIKVVESNRERAQAIAEGLSRSVVLHGDSLAREILDEAGVADSDTMIALTNDDRVNILSCL
LAKQLGAQRILALVNEQGYAGFAHGLGIDAYVNPRQITVSKVLQHVRRGRIRGVHSLLDGAGEMIEAEALETSPLVGRPL
RDIDLLKGMRIGAVVRNGVVMRPSGDTVVRAQDRVVLFALADDIKRVEQLFRVSLEFF

Specific function: Part of a potassium transport system

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains

Homologues:

Organism=Escherichia coli, GI1789685, Length=463, Percent_Identity=39.7408207343413, Blast_Score=318, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRKA_AZOC5 (Q04856)

Other databases:

- EMBL:   AP009384
- EMBL:   X63841
- PIR:   S18626
- RefSeq:   YP_001525998.1
- ProteinModelPortal:   Q04856
- GeneID:   5692244
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_3082
- HOGENOM:   HBG697234
- OMA:   HTPTKIA
- ProtClustDB:   PRK09496
- BioCyc:   ACAU438753:AZC_3082-MONOMER
- GO:   GO:0005488
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148
- Gene3D:   G3DSA:3.40.50.720
- PRINTS:   PR00335

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N

EC number: NA

Molecular weight: Translated: 49335; Mature: 49335

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS51202 RCK_C; PS51201 RCK_N

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVICGAGQVGFGIAERLASEQNDVSIVDASPRRIQIATDQLDVRGVVGHGSHPDVLAR
CEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCEEEEEEECCCCCCHHHHH
AGIEQADMLIAVTLHDEVNMVACQVGHSLFNVPTKVARIRAQTYLQPEWRSMLSRDHMPI
CCCCCCCEEEEEEECCCCCCHHHHHCHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCCCCE
DVVISPEIEVGEMVLRRLSLPGAVDTVSFGDGSVVIAGVLCGEACPVVDTPLTQLTQLFP
EEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHCC
DLPATIVAINRNGKVMATRSSDQIQTGDIAYFVAPADQVGRTLSIFGHDEIPAKRIIIGG
CCCEEEEEECCCCEEEEECCCCCEEECCEEEEECCHHHHCCEEEEECCCCCCCEEEEEEC
GGNIGLYVAQELEKRNAAARIKVVESNRERAQAIAEGLSRSVVLHGDSLAREILDEAGVA
CCCEEEEEHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCC
DSDTMIALTNDDRVNILSCLLAKQLGAQRILALVNEQGYAGFAHGLGIDAYVNPRQITVS
CCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCEEHHCCCCCEEECCCEEEHH
KVLQHVRRGRIRGVHSLLDGAGEMIEAEALETSPLVGRPLRDIDLLKGMRIGAVVRNGVV
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHCCEE
MRPSGDTVVRAQDRVVLFALADDIKRVEQLFRVSLEFF
ECCCCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVVICGAGQVGFGIAERLASEQNDVSIVDASPRRIQIATDQLDVRGVVGHGSHPDVLAR
CEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCEEEEEEECCCCCCHHHHH
AGIEQADMLIAVTLHDEVNMVACQVGHSLFNVPTKVARIRAQTYLQPEWRSMLSRDHMPI
CCCCCCCEEEEEEECCCCCCHHHHHCHHHHCCCHHHHHHHHHHCCCHHHHHHHCCCCCCE
DVVISPEIEVGEMVLRRLSLPGAVDTVSFGDGSVVIAGVLCGEACPVVDTPLTQLTQLFP
EEEECCCCCHHHHHHHHHCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHCC
DLPATIVAINRNGKVMATRSSDQIQTGDIAYFVAPADQVGRTLSIFGHDEIPAKRIIIGG
CCCEEEEEECCCCEEEEECCCCCEEECCEEEEECCHHHHCCEEEEECCCCCCCEEEEEEC
GGNIGLYVAQELEKRNAAARIKVVESNRERAQAIAEGLSRSVVLHGDSLAREILDEAGVA
CCCEEEEEHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCC
DSDTMIALTNDDRVNILSCLLAKQLGAQRILALVNEQGYAGFAHGLGIDAYVNPRQITVS
CCCCEEEEECCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCEEHHCCCCCEEECCCEEEHH
KVLQHVRRGRIRGVHSLLDGAGEMIEAEALETSPLVGRPLRDIDLLKGMRIGAVVRNGVV
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHCCEE
MRPSGDTVVRAQDRVVLFALADDIKRVEQLFRVSLEFF
ECCCCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370