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The map label for this gene is lysR [H]

Identifier: 158424642

GI number: 158424642

Start: 3450231

End: 3451166

Strand: Direct

Name: lysR [H]

Synonym: AZC_3018

Alternate gene names: 158424642

Gene position: 3450231-3451166 (Clockwise)

Preceding gene: 158424638

Following gene: 158424643

Centisome position: 64.25

GC content: 69.55

Gene sequence:

>936_bases
ATGCCCTTTCGTCCGTCCCATCGCCAGCTGGAGTATGCGGTCGCCTTGGCCGAAACCGGCCATTTCGGTTCCGCGGCCAA
GCGCTGCCACGTCTCGCAGCCCACCCTCTCGGTCCAGATTGCGCAGCTCGAACAGCAGCTCGGCACGCCCCTGTTCGACC
GCACGCGGGCGAAGGTGACGCCGACCGCCATCGGGGCACGCATCGTGGAGGCGGCGCGCTCGGTGCTGCTGACGCTGGAC
GACATCGTGACGGTGGCGGCCACCGGCGCGGACAATCTCGGCGGCCTCATCCGCCTCGGCGTCGCGCCCACCTTCGGACC
GTATTTCCTGCCGAACCTCCTGCCGGTGCTGCACGGCAAATATCCCGCGCTCCAGATCTACGTGCGAGAGGACCGGCCCG
CCGCCATCGAGCGCGACGTGATGACGGGCGATCTCGACTGCGGGCTCATTCCGCCCCCCGCCTCGGGCCACGCCCTCACC
TTCCGCCGCATCTGCCGGGAGGCCATTTATCTCGGCGTCGGCAAGGACCACCGCCTCGCCGCGAGCGGTCGCGTCAAGCC
CCGCCAGCTCAAGGGTGAGCGCCTGCTCACACTCGGGCGCGGCCACCATTTATTCGAGCGGGCGCGGGAGCTGGCGGCGG
CGAGCGGCGCCGACATGCGGGAAGATTATGAGGGCACGAGCCTCGATGCCCTGCGCCAGATGGTGGTGATGGGCATGGGC
GCGTCCCTCTTCCCGGAACTCTATGCCAAATCCGAATTCCGCGTGCAGGATCACGTCGCCCTGCTGCAGATCGACGGCTG
GCCGGCGAGCCGCGACATGGGCTACATCTGGCGGGCGAGCAACGGGCGGGCCGCCCAGTTCGAGGAACTGGCGCGGGAGA
GCGAGCAGGCGTGCGCGGCGCTGGGGCTCAGCGATGAGCCGCCAAAGCACGCCTGA

Upstream 100 bases:

>100_bases
ACAACCTCCTTTCAACGGGGAGGAGCATGCGGGATCGGACTTGATAGGTCCAATGCATAGTTTCTATATTCTCCATAGCC
TCGAACTATCGTGAACCGCC

Downstream 100 bases:

>100_bases
CGGGGAACGTTCGGCCAAGGCGCCCGTTCGACGACCGGGACACAGCGCGTGATTTCGGGAGCGCGCGGGGCGGAGCGTCA
CAGCTTTGTCATCAATGGCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MPFRPSHRQLEYAVALAETGHFGSAAKRCHVSQPTLSVQIAQLEQQLGTPLFDRTRAKVTPTAIGARIVEAARSVLLTLD
DIVTVAATGADNLGGLIRLGVAPTFGPYFLPNLLPVLHGKYPALQIYVREDRPAAIERDVMTGDLDCGLIPPPASGHALT
FRRICREAIYLGVGKDHRLAASGRVKPRQLKGERLLTLGRGHHLFERARELAAASGADMREDYEGTSLDALRQMVVMGMG
ASLFPELYAKSEFRVQDHVALLQIDGWPASRDMGYIWRASNGRAAQFEELARESEQACAALGLSDEPPKHA

Sequences:

>Translated_311_residues
MPFRPSHRQLEYAVALAETGHFGSAAKRCHVSQPTLSVQIAQLEQQLGTPLFDRTRAKVTPTAIGARIVEAARSVLLTLD
DIVTVAATGADNLGGLIRLGVAPTFGPYFLPNLLPVLHGKYPALQIYVREDRPAAIERDVMTGDLDCGLIPPPASGHALT
FRRICREAIYLGVGKDHRLAASGRVKPRQLKGERLLTLGRGHHLFERARELAAASGADMREDYEGTSLDALRQMVVMGMG
ASLFPELYAKSEFRVQDHVALLQIDGWPASRDMGYIWRASNGRAAQFEELARESEQACAALGLSDEPPKHA
>Mature_310_residues
PFRPSHRQLEYAVALAETGHFGSAAKRCHVSQPTLSVQIAQLEQQLGTPLFDRTRAKVTPTAIGARIVEAARSVLLTLDD
IVTVAATGADNLGGLIRLGVAPTFGPYFLPNLLPVLHGKYPALQIYVREDRPAAIERDVMTGDLDCGLIPPPASGHALTF
RRICREAIYLGVGKDHRLAASGRVKPRQLKGERLLTLGRGHHLFERARELAAASGADMREDYEGTSLDALRQMVVMGMGA
SLFPELYAKSEFRVQDHVALLQIDGWPASRDMGYIWRASNGRAAQFEELARESEQACAALGLSDEPPKHA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=284, Percent_Identity=36.6197183098592, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI157672245, Length=238, Percent_Identity=30.2521008403361, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693105, Length=236, Percent_Identity=26.6949152542373, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367136, Length=261, Percent_Identity=28.3524904214559, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787879, Length=287, Percent_Identity=27.8745644599303, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789204, Length=248, Percent_Identity=26.6129032258064, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788887, Length=240, Percent_Identity=26.25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=25.8823529411765, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788748, Length=192, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=25.6, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787806, Length=276, Percent_Identity=23.1884057971014, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33922; Mature: 33791

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFRPSHRQLEYAVALAETGHFGSAAKRCHVSQPTLSVQIAQLEQQLGTPLFDRTRAKVT
CCCCCCCHHHHEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCC
PTAIGARIVEAARSVLLTLDDIVTVAATGADNLGGLIRLGVAPTFGPYFLPNLLPVLHGK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCC
YPALQIYVREDRPAAIERDVMTGDLDCGLIPPPASGHALTFRRICREAIYLGVGKDHRLA
CCEEEEEEECCCCCHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
ASGRVKPRQLKGERLLTLGRGHHLFERARELAAASGADMREDYEGTSLDALRQMVVMGMG
CCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHCCC
ASLFPELYAKSEFRVQDHVALLQIDGWPASRDMGYIWRASNGRAAQFEELARESEQACAA
HHHHHHHHCCCCCEEECCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
LGLSDEPPKHA
CCCCCCCCCCC
>Mature Secondary Structure 
PFRPSHRQLEYAVALAETGHFGSAAKRCHVSQPTLSVQIAQLEQQLGTPLFDRTRAKVT
CCCCCCHHHHEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCC
PTAIGARIVEAARSVLLTLDDIVTVAATGADNLGGLIRLGVAPTFGPYFLPNLLPVLHGK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCC
YPALQIYVREDRPAAIERDVMTGDLDCGLIPPPASGHALTFRRICREAIYLGVGKDHRLA
CCEEEEEEECCCCCHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEE
ASGRVKPRQLKGERLLTLGRGHHLFERARELAAASGADMREDYEGTSLDALRQMVVMGMG
CCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHCCC
ASLFPELYAKSEFRVQDHVALLQIDGWPASRDMGYIWRASNGRAAQFEELARESEQACAA
HHHHHHHHCCCCCEEECCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
LGLSDEPPKHA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA