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The map label for this gene is speF [H]

Identifier: 158424643

GI number: 158424643

Start: 3451305

End: 3453662

Strand: Direct

Name: speF [H]

Synonym: AZC_3019

Alternate gene names: 158424643

Gene position: 3451305-3453662 (Clockwise)

Preceding gene: 158424642

Following gene: 158424644

Centisome position: 64.27

GC content: 65.39

Gene sequence:

>2358_bases
ATGGATTATTTCCGCCGCTTCACCTTCCTGTTCGCGACCCCCGCCTTCGACGCGGACGACCTCGAGGGCGTCCGCCTCAA
CCAGATCGTGGACGAGATCGGCCGCGCCGGCTTCGAGGTGGTGATGGCGCGCGATCTCGATGACGCGCAGATCGCGGTGC
AGACGGACGCCGCCATCGGCTGCATGCTCATCGACTGGGGCAAGAAGGGGCTGGAGGGCAAGACCGCCGCTCTCATCAAC
CTTATGCGTAAGCGCGGGCTCGACTTCCCCATCATCCTGCTGGTGCGGCGCAAGCGCTTCGAGGATCTGCCGGTCGAAGT
GCTGGACTTCATCGACGGCTACGTCTTCCTCTCGGAAGAGACCCCCGCCTTCATCGCCAAGAACCTCGTTTCCCGGCTCA
AGCAATACGCCGAGACGCTGAAGACACCCTTCTTCGGCGCGCTGGTGGATTATGCGGAGGAAGGCAACCAGCTGTGGACC
TGCCCAGGCCACAACGGCGGCGTGTTCTACAGCCGCAGCCCCATTGGCCGGGTGTTCATGGAGCATCTCGGCGAGGCCGT
GTTCCGCGACGACCTCGACAATTCCGTGCTTGATCTCGGCGACCTGCTGACCCACGAGGGCCCCGCCCTTCAGGCGCAGA
AGGAAGCCGCCAAGATCTTCGGCGCGGAGAAGACCTATTTCGTGCTGAACGGCACCTCCACCTCCAACAAGGTGGCGCTC
TCCGCCCTCGTGACCGACGGCGACCTCGTGCTGTTCGACCGCAACAACCACAAGGCCGCCCACCATGGCGCGCTGCTCAT
CGGCGGCGGCATCCCGGTCTATGTGCCCACCGTGCGCAACGCCTGGGGCCTCATCGGCCCGATGCGCTGGGACAAGCTGG
ACGAGACGGCGCTGCGCGAGGCCATTCGCACCAATCCGCTGGTGAGCGATCCCGATGCCTGGCAGCGCCCCCGCCCCTTC
CGGGTCGCAGTGGTGGAGCAGTGCACCTATGACGGCACCATCCACAATGCCGAGATGATCCTGAAGCGGATCGGCCACCT
GTGCGACTACATCCTGTTCGATGAGGCCTGGGCGGGCTTCATGAAGTTCCACCCGCTCTATGCGGGCCGCTACGCCATGG
GCCTTTCCGACCTCGGTCCGGACTCGCCCGGCATCATCGCCACCCAGTCCACCCACAAGCAACTGGCGAGCTTCTCGCAG
GCCTCGCAGATCCACATGAAGGACCGGCACATCACCGGCCAGAAGCGGCGCGTGGAGCATCGCCGCTTCAACGAGAGCTT
CATGCAGCACGCCTCCACCTCGCCTTTCTATCCGCTGTTCGCCTCCCTCGACGTGGGCGCCCAGATGATGAAGGGGCGTT
CGGGTGAGGTGCTGTGGGACGATACGATCCGGCTCGGCATCGAGCTGCGCAAGAAGATCCGCGCCAGCCGCCGCGAGTTC
GAGGAGAAGGAGAGCCGGCCGGAACGGCGCTGGTTCTTCGAGCCCTTCGTGCCCGAGCGCGTGGCCATTCCCGATGCTGC
CCGCCCCGGTGCGTTCCATGACGTGCCGTGGGAAAGCGTGGGCACCGACCAGCTCGCCACCGATCCCGCCTTCTGGCAAC
TGGCGCCCGAGGCAAAGTGGCATGGTTTCGGCGATCTGGCGCCGGGCTTTGCCATGACGGATCCCAACAAGCTCACCCTG
CTGACCCCTGGCTTCGACCGGACTACGGGCGACTATACGGAGCACGGCATTCCGGCCCCGGTGGTGGCGCAATATCTGCG
CGAGAACCGCATCGTGCCGGAGAAGAACGACCTCAACTCGCTGCTCTTCCTCCTCACCCCCGGCGTCGAGGCCAGCAAGG
CGGGTACGCTCATCTCCGGCCTCGTCGCCTTCAAGCGCCTGCATGACGACAACGCGCTGCTGGAGGACGCGATTCCGGAA
TTCTTCCGCCGCCGGCCGCAGCGCTATGCCGGCGTGCGCCTGCGCGACCTGTGCGGGGAGATGCACCGCTTCTTCCGCGA
GGCGAATGTGAGCCGCCTGCAGGCCCAGCAGTTCTGCCCCGAGCATCTGCCGGAAATGGCCATGTCGCCCCACGACGCCG
CCCGCTGCCTCGTGCGCAACGATGTGGACTATCTGCCCATCGACGCCATCTCGGGCCGCATCGCCACAACGCCCTTCGTG
GTCTATCCGCCGGGCATCGCCACCATCGTGCCGGGCGAGCGCCTGACGGAACGCGCGCAGCCCATGATCGATTATCTCAG
GATGTTCGAGGCGAGCTTCAACACCTTCCCCGGCTTCGAGGTTGAAATTCAGGGCGTTTACCGCGAGATCGATGCCACGG
GGCGGGTGCGGCTCTATACCTATGTGGTCAGCGAATAG

Upstream 100 bases:

>100_bases
GACACAGCGCGTGATTTCGGGAGCGCGCGGGGCGGAGCGTCACAGCTTTGTCATCAATGGCAGGACATCTGCACCCCGAG
CTCAGCCCCCGGGGACGATG

Downstream 100 bases:

>100_bases
GATTGCGTCAGGACGCCATGGAGACAGACACCGCCATCGTCATCCGCCCCACCCGTGACGAGGATGTGGATGCGATGCTT
GCCATTTACCGTCACCACAT

Product: arginine/lysine/ornithine decarboxylases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MDYFRRFTFLFATPAFDADDLEGVRLNQIVDEIGRAGFEVVMARDLDDAQIAVQTDAAIGCMLIDWGKKGLEGKTAALIN
LMRKRGLDFPIILLVRRKRFEDLPVEVLDFIDGYVFLSEETPAFIAKNLVSRLKQYAETLKTPFFGALVDYAEEGNQLWT
CPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALQAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
SALVTDGDLVLFDRNNHKAAHHGALLIGGGIPVYVPTVRNAWGLIGPMRWDKLDETALREAIRTNPLVSDPDAWQRPRPF
RVAVVEQCTYDGTIHNAEMILKRIGHLCDYILFDEAWAGFMKFHPLYAGRYAMGLSDLGPDSPGIIATQSTHKQLASFSQ
ASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRASRREF
EEKESRPERRWFFEPFVPERVAIPDAARPGAFHDVPWESVGTDQLATDPAFWQLAPEAKWHGFGDLAPGFAMTDPNKLTL
LTPGFDRTTGDYTEHGIPAPVVAQYLRENRIVPEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKRLHDDNALLEDAIPE
FFRRRPQRYAGVRLRDLCGEMHRFFREANVSRLQAQQFCPEHLPEMAMSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
VYPPGIATIVPGERLTERAQPMIDYLRMFEASFNTFPGFEVEIQGVYREIDATGRVRLYTYVVSE

Sequences:

>Translated_785_residues
MDYFRRFTFLFATPAFDADDLEGVRLNQIVDEIGRAGFEVVMARDLDDAQIAVQTDAAIGCMLIDWGKKGLEGKTAALIN
LMRKRGLDFPIILLVRRKRFEDLPVEVLDFIDGYVFLSEETPAFIAKNLVSRLKQYAETLKTPFFGALVDYAEEGNQLWT
CPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALQAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
SALVTDGDLVLFDRNNHKAAHHGALLIGGGIPVYVPTVRNAWGLIGPMRWDKLDETALREAIRTNPLVSDPDAWQRPRPF
RVAVVEQCTYDGTIHNAEMILKRIGHLCDYILFDEAWAGFMKFHPLYAGRYAMGLSDLGPDSPGIIATQSTHKQLASFSQ
ASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRASRREF
EEKESRPERRWFFEPFVPERVAIPDAARPGAFHDVPWESVGTDQLATDPAFWQLAPEAKWHGFGDLAPGFAMTDPNKLTL
LTPGFDRTTGDYTEHGIPAPVVAQYLRENRIVPEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKRLHDDNALLEDAIPE
FFRRRPQRYAGVRLRDLCGEMHRFFREANVSRLQAQQFCPEHLPEMAMSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
VYPPGIATIVPGERLTERAQPMIDYLRMFEASFNTFPGFEVEIQGVYREIDATGRVRLYTYVVSE
>Mature_785_residues
MDYFRRFTFLFATPAFDADDLEGVRLNQIVDEIGRAGFEVVMARDLDDAQIAVQTDAAIGCMLIDWGKKGLEGKTAALIN
LMRKRGLDFPIILLVRRKRFEDLPVEVLDFIDGYVFLSEETPAFIAKNLVSRLKQYAETLKTPFFGALVDYAEEGNQLWT
CPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALQAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
SALVTDGDLVLFDRNNHKAAHHGALLIGGGIPVYVPTVRNAWGLIGPMRWDKLDETALREAIRTNPLVSDPDAWQRPRPF
RVAVVEQCTYDGTIHNAEMILKRIGHLCDYILFDEAWAGFMKFHPLYAGRYAMGLSDLGPDSPGIIATQSTHKQLASFSQ
ASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRASRREF
EEKESRPERRWFFEPFVPERVAIPDAARPGAFHDVPWESVGTDQLATDPAFWQLAPEAKWHGFGDLAPGFAMTDPNKLTL
LTPGFDRTTGDYTEHGIPAPVVAQYLRENRIVPEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKRLHDDNALLEDAIPE
FFRRRPQRYAGVRLRDLCGEMHRFFREANVSRLQAQQFCPEHLPEMAMSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
VYPPGIATIVPGERLTERAQPMIDYLRMFEASFNTFPGFEVEIQGVYREIDATGRVRLYTYVVSE

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=714, Percent_Identity=43.9775910364146, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI87082193, Length=708, Percent_Identity=44.0677966101695, Blast_Score=574, Evalue=1e-165,
Organism=Escherichia coli, GI221142684, Length=751, Percent_Identity=33.155792276964, Blast_Score=441, Evalue=1e-124,
Organism=Escherichia coli, GI1790573, Length=744, Percent_Identity=30.9139784946237, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1786384, Length=742, Percent_Identity=31.266846361186, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 88477; Mature: 88477

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYFRRFTFLFATPAFDADDLEGVRLNQIVDEIGRAGFEVVMARDLDDAQIAVQTDAAIG
CCHHHHEEHEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCEE
CMLIDWGKKGLEGKTAALINLMRKRGLDFPIILLVRRKRFEDLPVEVLDFIDGYVFLSEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCEEEECCC
TPAFIAKNLVSRLKQYAETLKTPFFGALVDYAEEGNQLWTCPGHNGGVFYSRSPIGRVFM
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCEEEECCCHHHHHH
EHLGEAVFRDDLDNSVLDLGDLLTHEGPALQAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEE
SALVTDGDLVLFDRNNHKAAHHGALLIGGGIPVYVPTVRNAWGLIGPMRWDKLDETALRE
EEEEECCCEEEEECCCCCCHHCCEEEECCCCEEEECCHHCCCCCCCCCCCCCCHHHHHHH
AIRTNPLVSDPDAWQRPRPFRVAVVEQCTYDGTIHNAEMILKRIGHLCDYILFDEAWAGF
HHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKFHPLYAGRYAMGLSDLGPDSPGIIATQSTHKQLASFSQASQIHMKDRHITGQKRRVEH
HHHCHHHCCHHHCCHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRASRREF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
EEKESRPERRWFFEPFVPERVAIPDAARPGAFHDVPWESVGTDQLATDPAFWQLAPEAKW
HHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
HGFGDLAPGFAMTDPNKLTLLTPGFDRTTGDYTEHGIPAPVVAQYLRENRIVPEKNDLNS
CCCCCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
LLFLLTPGVEASKAGTLISGLVAFKRLHDDNALLEDAIPEFFRRRPQRYAGVRLRDLCGE
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCHHHHHHHH
MHRFFREANVSRLQAQQFCPEHLPEMAMSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
HHHHHHHCCHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHCCCCEECCCEE
VYPPGIATIVPGERLTERAQPMIDYLRMFEASFNTFPGFEVEIQGVYREIDATGRVRLYT
EECCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCCCCEEEEE
YVVSE
EEECC
>Mature Secondary Structure
MDYFRRFTFLFATPAFDADDLEGVRLNQIVDEIGRAGFEVVMARDLDDAQIAVQTDAAIG
CCHHHHEEHEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCEE
CMLIDWGKKGLEGKTAALINLMRKRGLDFPIILLVRRKRFEDLPVEVLDFIDGYVFLSEE
EEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHCCEEEECCC
TPAFIAKNLVSRLKQYAETLKTPFFGALVDYAEEGNQLWTCPGHNGGVFYSRSPIGRVFM
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCEEEECCCHHHHHH
EHLGEAVFRDDLDNSVLDLGDLLTHEGPALQAQKEAAKIFGAEKTYFVLNGTSTSNKVAL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEEE
SALVTDGDLVLFDRNNHKAAHHGALLIGGGIPVYVPTVRNAWGLIGPMRWDKLDETALRE
EEEEECCCEEEEECCCCCCHHCCEEEECCCCEEEECCHHCCCCCCCCCCCCCCHHHHHHH
AIRTNPLVSDPDAWQRPRPFRVAVVEQCTYDGTIHNAEMILKRIGHLCDYILFDEAWAGF
HHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MKFHPLYAGRYAMGLSDLGPDSPGIIATQSTHKQLASFSQASQIHMKDRHITGQKRRVEH
HHHCHHHCCHHHCCHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRASRREF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHH
EEKESRPERRWFFEPFVPERVAIPDAARPGAFHDVPWESVGTDQLATDPAFWQLAPEAKW
HHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCC
HGFGDLAPGFAMTDPNKLTLLTPGFDRTTGDYTEHGIPAPVVAQYLRENRIVPEKNDLNS
CCCCCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
LLFLLTPGVEASKAGTLISGLVAFKRLHDDNALLEDAIPEFFRRRPQRYAGVRLRDLCGE
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHCCHHHHHHHH
MHRFFREANVSRLQAQQFCPEHLPEMAMSPHDAARCLVRNDVDYLPIDAISGRIATTPFV
HHHHHHHCCHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHCCCCEECCCEE
VYPPGIATIVPGERLTERAQPMIDYLRMFEASFNTFPGFEVEIQGVYREIDATGRVRLYT
EECCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHCCCCCEEEEE
YVVSE
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]