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The map label for this gene is recQ [H]

Identifier: 158424466

GI number: 158424466

Start: 3235389

End: 3237215

Strand: Direct

Name: recQ [H]

Synonym: AZC_2842

Alternate gene names: 158424466

Gene position: 3235389-3237215 (Clockwise)

Preceding gene: 158424465

Following gene: 158424467

Centisome position: 60.25

GC content: 69.29

Gene sequence:

>1827_bases
ATGCTCCCCGTTCTGCCGCTTGAGTCGCACTCCGATCCCCGGGACGTGCTGCGTCACGTCTTCGGCTACGACAGCTTCCG
GGGACGTCAGGCGGAGATCGTCGACCATGTGGTCGCCGGCGGCGACGCGCTGGTGCTCATGCCCACAGGCGGCGGCAAGT
CGCTCTGCTATCAGGTGCCGGCGCTGGTGCGGCCGGGCACCGGCATCGTCATCTCCCCCCTCATCGCCCTCATGCACGAC
CAGGTGCAGGCCCTGCGCCAGCTGGGCGTGCGGGCGGCGGCGCTCAATTCCACACTCCAGCCCGCAGAGGCGCGGCAGGT
GGAGCGCCAGCTCGCCATGGGCGAGCTCGACCTGCTCTATGTGGCCCCCGAGCGCCTGCTGACGGACAGCTTCCTGACCC
TGCTGCAAGGGGCGCGCATTGCCCTCTTCGCCATCGACGAGGCGCACTGCGTCTCCCAGTGGGGCCACGATTTCCGCCCG
GAATACCGCCAGCTCACACTGCTGCACGAGCGCTTCCCCTCCGTGCCGCGCATCGCGCTCACCGCCACCGCCGACGGGCC
GACCCGGCGCGAGATCGTGGAGCGGCTGGGGCTGGAGAACGGCCGCGTCTTCCTCTCCAGCTTCGACCGGCCGAACATCC
GCTACCGGATCGCGCCGAAGGCCAATCCCAAGGCGCAACTGCGGGCCTTCCTCGACGACCATGAGGGAGAGGCGGGCGTC
ATCTACTGCATGAGCCGCGCCAAGGTGGAGCAGACGGCGCAGGCGCTGGTGGACGAGGGCCGCTTCGCGTTGCCCTATCA
TGCCGGCCTCGATGCGGAGACCCGCGCCCGCCATCAGGACCGATTCCTGAAGGAGGAAGGGGTCATCATGGTGGCCACCA
TCGCCTTCGGCATGGGCATCGACAAGCCGGACGTGCGCTTCGTTGTCCATCTCGACCTGCCCAAGAGCATCGAGGCCTAT
TATCAGGAGACCGGCCGCGCCGGCCGCGACGGCCTGCCGTCCGAGGCGCTGCTGCTCTATGGCGTCGAGGATGTGGCGAA
ACTCATCCAGTTCGTGGAGGCCTCCGACGCGCCCGACGCCCGCAAACGGGTGGAACGGCAGAAGCTCGATGCGTTGCTCG
GCCTTTGCGAGACGGCGAGTTGCCGCCGGCAGGTGCTGCTCTCTTATTTCGAGGAGACGCTGGACGAGCCCTGCGGCAAT
TGCGACACCTGCCTTGAGCCGGTGAAGACCTTCGACGGCACGGAAGCGGTGCAGAAGCTGCTCTCCTGCGTCTATCGCAC
CGAGCAGCGCTTCGGCGCCGGCCATGTGATCGACGTGCTGCTGGGCGTGGCAAACGAGCGGGCGCAGCGGCTCGGCCACG
ACAAGCTCTCCACCTTCGGCATCGGCACCGACCTCTCCCGCGACGAATGGCGGGCGGTGGTGCGGCAGGTGGTGGCCCTC
GGCCTCCTGAAAGTGGATGTGGAAGGCCACGGCGGCCTCAGCCTCTCGGACGACTGCCGGCCGGTGCTGCGCGGCGAGCG
GCGCGTGCAACTCAAGGCCGAGAAGCGCACGAAGCCGGCGCGCGCCACGGGCGGCGCCCGCGCGCCGCGGCCCACGCTCT
CGACGCCCGATGACGAGCGCCTTTACCAGAAGCTCCGCGCGCTGCGGCTTGAACTGGCGCGCGCGCAGAGCGTTCCCCCT
TACGTGATCTTCCACGATGCCACGCTGATGGAGATCGTGCGCGTGCGCCCGCGCTCGCTGGCGGCGCTGGGGGATGTGTC
AGGGGTGGGCGAGGCCAAGCTGGAGCGCTACGGACCGGTGTTTCTGGAGGCGGTGCGGGCCGGCTGA

Upstream 100 bases:

>100_bases
GGTGCCGAACAGCGGGGAAAGCTTCGAGGTCTGAGCCTCCTCACCCCCCGCCCGGTGTCGCGATGCGTTGCCCGCGCGCC
GGGCGGGAGTATAAGGGGCC

Downstream 100 bases:

>100_bases
AGGTGTGTTCCGAAGCCGGTGGGTCATGCGTCTGGCCCCGGCATGAGGCTTTCACCCGCCCGATGCCCTTGCTATAGCGG
CCTTAGTTTTAAGGAGCATG

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MLPVLPLESHSDPRDVLRHVFGYDSFRGRQAEIVDHVVAGGDALVLMPTGGGKSLCYQVPALVRPGTGIVISPLIALMHD
QVQALRQLGVRAAALNSTLQPAEARQVERQLAMGELDLLYVAPERLLTDSFLTLLQGARIALFAIDEAHCVSQWGHDFRP
EYRQLTLLHERFPSVPRIALTATADGPTRREIVERLGLENGRVFLSSFDRPNIRYRIAPKANPKAQLRAFLDDHEGEAGV
IYCMSRAKVEQTAQALVDEGRFALPYHAGLDAETRARHQDRFLKEEGVIMVATIAFGMGIDKPDVRFVVHLDLPKSIEAY
YQETGRAGRDGLPSEALLLYGVEDVAKLIQFVEASDAPDARKRVERQKLDALLGLCETASCRRQVLLSYFEETLDEPCGN
CDTCLEPVKTFDGTEAVQKLLSCVYRTEQRFGAGHVIDVLLGVANERAQRLGHDKLSTFGIGTDLSRDEWRAVVRQVVAL
GLLKVDVEGHGGLSLSDDCRPVLRGERRVQLKAEKRTKPARATGGARAPRPTLSTPDDERLYQKLRALRLELARAQSVPP
YVIFHDATLMEIVRVRPRSLAALGDVSGVGEAKLERYGPVFLEAVRAG

Sequences:

>Translated_608_residues
MLPVLPLESHSDPRDVLRHVFGYDSFRGRQAEIVDHVVAGGDALVLMPTGGGKSLCYQVPALVRPGTGIVISPLIALMHD
QVQALRQLGVRAAALNSTLQPAEARQVERQLAMGELDLLYVAPERLLTDSFLTLLQGARIALFAIDEAHCVSQWGHDFRP
EYRQLTLLHERFPSVPRIALTATADGPTRREIVERLGLENGRVFLSSFDRPNIRYRIAPKANPKAQLRAFLDDHEGEAGV
IYCMSRAKVEQTAQALVDEGRFALPYHAGLDAETRARHQDRFLKEEGVIMVATIAFGMGIDKPDVRFVVHLDLPKSIEAY
YQETGRAGRDGLPSEALLLYGVEDVAKLIQFVEASDAPDARKRVERQKLDALLGLCETASCRRQVLLSYFEETLDEPCGN
CDTCLEPVKTFDGTEAVQKLLSCVYRTEQRFGAGHVIDVLLGVANERAQRLGHDKLSTFGIGTDLSRDEWRAVVRQVVAL
GLLKVDVEGHGGLSLSDDCRPVLRGERRVQLKAEKRTKPARATGGARAPRPTLSTPDDERLYQKLRALRLELARAQSVPP
YVIFHDATLMEIVRVRPRSLAALGDVSGVGEAKLERYGPVFLEAVRAG
>Mature_608_residues
MLPVLPLESHSDPRDVLRHVFGYDSFRGRQAEIVDHVVAGGDALVLMPTGGGKSLCYQVPALVRPGTGIVISPLIALMHD
QVQALRQLGVRAAALNSTLQPAEARQVERQLAMGELDLLYVAPERLLTDSFLTLLQGARIALFAIDEAHCVSQWGHDFRP
EYRQLTLLHERFPSVPRIALTATADGPTRREIVERLGLENGRVFLSSFDRPNIRYRIAPKANPKAQLRAFLDDHEGEAGV
IYCMSRAKVEQTAQALVDEGRFALPYHAGLDAETRARHQDRFLKEEGVIMVATIAFGMGIDKPDVRFVVHLDLPKSIEAY
YQETGRAGRDGLPSEALLLYGVEDVAKLIQFVEASDAPDARKRVERQKLDALLGLCETASCRRQVLLSYFEETLDEPCGN
CDTCLEPVKTFDGTEAVQKLLSCVYRTEQRFGAGHVIDVLLGVANERAQRLGHDKLSTFGIGTDLSRDEWRAVVRQVVAL
GLLKVDVEGHGGLSLSDDCRPVLRGERRVQLKAEKRTKPARATGGARAPRPTLSTPDDERLYQKLRALRLELARAQSVPP
YVIFHDATLMEIVRVRPRSLAALGDVSGVGEAKLERYGPVFLEAVRAG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=627, Percent_Identity=34.6092503987241, Blast_Score=345, Evalue=8e-95,
Organism=Homo sapiens, GI14591902, Length=411, Percent_Identity=38.9294403892944, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI14591904, Length=411, Percent_Identity=38.9294403892944, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI110735439, Length=693, Percent_Identity=30.1587301587302, Blast_Score=279, Evalue=5e-75,
Organism=Homo sapiens, GI169218196, Length=693, Percent_Identity=30.1587301587302, Blast_Score=279, Evalue=6e-75,
Organism=Homo sapiens, GI148612816, Length=448, Percent_Identity=37.0535714285714, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI51242943, Length=401, Percent_Identity=38.1546134663342, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI51242947, Length=401, Percent_Identity=38.1546134663342, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI284005309, Length=384, Percent_Identity=34.375, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI48994977, Length=605, Percent_Identity=48.9256198347107, Blast_Score=578, Evalue=1e-166,
Organism=Escherichia coli, GI87082221, Length=331, Percent_Identity=23.2628398791541, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=498, Percent_Identity=38.7550200803213, Blast_Score=351, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI71987997, Length=420, Percent_Identity=38.3333333333333, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71987993, Length=420, Percent_Identity=38.3333333333333, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI32564293, Length=672, Percent_Identity=31.1011904761905, Blast_Score=283, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17552866, Length=448, Percent_Identity=36.8303571428571, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17555296, Length=337, Percent_Identity=24.3323442136499, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=524, Percent_Identity=34.5419847328244, Blast_Score=319, Evalue=6e-88,
Organism=Saccharomyces cerevisiae, GI6323947, Length=363, Percent_Identity=23.9669421487603, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324217, Length=380, Percent_Identity=22.6315789473684, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646066, Length=630, Percent_Identity=35.8730158730159, Blast_Score=367, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=445, Percent_Identity=37.0786516853933, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI62472181, Length=445, Percent_Identity=37.0786516853933, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24664230, Length=445, Percent_Identity=37.0786516853933, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21358123, Length=354, Percent_Identity=37.8531073446328, Blast_Score=215, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67231; Mature: 67231

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVLPLESHSDPRDVLRHVFGYDSFRGRQAEIVDHVVAGGDALVLMPTGGGKSLCYQVP
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHCCC
ALVRPGTGIVISPLIALMHDQVQALRQLGVRAAALNSTLQPAEARQVERQLAMGELDLLY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEE
VAPERLLTDSFLTLLQGARIALFAIDEAHCVSQWGHDFRPEYRQLTLLHERFPSVPRIAL
ECHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEE
TATADGPTRREIVERLGLENGRVFLSSFDRPNIRYRIAPKANPKAQLRAFLDDHEGEAGV
EECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEE
IYCMSRAKVEQTAQALVDEGRFALPYHAGLDAETRARHQDRFLKEEGVIMVATIAFGMGI
EEEEHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCC
DKPDVRFVVHLDLPKSIEAYYQETGRAGRDGLPSEALLLYGVEDVAKLIQFVEASDAPDA
CCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCHH
RKRVERQKLDALLGLCETASCRRQVLLSYFEETLDEPCGNCDTCLEPVKTFDGTEAVQKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHH
LSCVYRTEQRFGAGHVIDVLLGVANERAQRLGHDKLSTFGIGTDLSRDEWRAVVRQVVAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
GLLKVDVEGHGGLSLSDDCRPVLRGERRVQLKAEKRTKPARATGGARAPRPTLSTPDDER
HHHEEEECCCCCCCCCCCCHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHH
LYQKLRALRLELARAQSVPPYVIFHDATLMEIVRVRPRSLAALGDVSGVGEAKLERYGPV
HHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHCHH
FLEAVRAG
HHHHHHCC
>Mature Secondary Structure
MLPVLPLESHSDPRDVLRHVFGYDSFRGRQAEIVDHVVAGGDALVLMPTGGGKSLCYQVP
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHCCC
ALVRPGTGIVISPLIALMHDQVQALRQLGVRAAALNSTLQPAEARQVERQLAMGELDLLY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEE
VAPERLLTDSFLTLLQGARIALFAIDEAHCVSQWGHDFRPEYRQLTLLHERFPSVPRIAL
ECHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEE
TATADGPTRREIVERLGLENGRVFLSSFDRPNIRYRIAPKANPKAQLRAFLDDHEGEAGV
EECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCEE
IYCMSRAKVEQTAQALVDEGRFALPYHAGLDAETRARHQDRFLKEEGVIMVATIAFGMGI
EEEEHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHCCC
DKPDVRFVVHLDLPKSIEAYYQETGRAGRDGLPSEALLLYGVEDVAKLIQFVEASDAPDA
CCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCHH
RKRVERQKLDALLGLCETASCRRQVLLSYFEETLDEPCGNCDTCLEPVKTFDGTEAVQKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHH
LSCVYRTEQRFGAGHVIDVLLGVANERAQRLGHDKLSTFGIGTDLSRDEWRAVVRQVVAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHH
GLLKVDVEGHGGLSLSDDCRPVLRGERRVQLKAEKRTKPARATGGARAPRPTLSTPDDER
HHHEEEECCCCCCCCCCCCHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCHHH
LYQKLRALRLELARAQSVPPYVIFHDATLMEIVRVRPRSLAALGDVSGVGEAKLERYGPV
HHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHCHH
FLEAVRAG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]