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The map label for this gene is hisC [H]

Identifier: 158424066

GI number: 158424066

Start: 2777938

End: 2779071

Strand: Reverse

Name: hisC [H]

Synonym: AZC_2442

Alternate gene names: 158424066

Gene position: 2779071-2777938 (Counterclockwise)

Preceding gene: 158424067

Following gene: 158424065

Centisome position: 51.75

GC content: 67.99

Gene sequence:

>1134_bases
ATGTCATCCGCCAGCCAGCGCAATCGCTATTTCGATGCGCTCTCCAGCACGCCCGGCCTCATGTGGCTGGGGCAGAACAC
CAATCACATCCCGGCCCATCCGGCGGTGAAGGCGGCGATGATCGCGGCCATCGAGGAAGGCGCCTTCAACGCCTATGCCC
CGCCGCTGGGCTTCGAGGCGCTGCGCGCGGCCATCGTCGCGGATCTCGGCACGCCCGGGGCCGAGGCGCTTGTGACGGAG
GGCGGCGTCTCCGCCCTCGCCATGGTGTGCCGCGCCTATTGCCGGCCGGGCACCACCTTCGTCACCACTGATCCCACATG
GAAGTGGCCCTGCCTCTTTGCGAAGCAGGCGGGCGCGGAGGTGATCGAGATCCCCATCTATGATCCCGCCTGCAACTATC
GCCTCACGCCCGAGGCGCTGAAAGCGGCGGTGGATGAGCGCACCGCCATCATCTATCTCGTGGACCCCAACAATCCGCTC
GGCATCCGCTACACGCGCGAGGAGATCGAGGCCTTCGCGGCCATCGCTCGCGACTGCGGCGCCATGCTGGTGCACGACTG
CACCTATCGCGATTTCGCGGATGGGCATTATCCGGCGCTGCTCGCCGCGCCAGAAGGCGCCATTGTCTCGCTCTCCTTCT
CCAAATGGCTTGGTCTTGCCGGCCTGCGCGTGGGCGCGCTGGTGGCGGCGCCCGCCGTGCTGGAGGCCTGCGCCGAGCGG
GCGACCAGCGTGCTGGGCGCCAGCGTCATCGCCCAGCGGGCGGCCGAGGCGGGGCTGAAGGTGAAGCCCGAATGGATGGG
AGAGGTGCGCCGCATCGATCGCGCCAACAAGGCGAAGATCAAGGAGGCTGCGTCCGCCATCGAAGGCTTCGCGTTGCCGG
TCTATCCCTCGCACGGCAATTTCCTCGTGCTGGAAACCATCGGCGCCGGCATCCGGCCCGAGGCACTGGTGGAAGCGGCC
CGGCGCGAGAAGATGATGATCCGGCAGGGAACCTATCACACGGCGCGCTTCGGCGACCGCTTCGTGAAAGTGAGCACCTC
GGTCCCGGAGGGCTGGGTGGATGCCTTCTGCGCGCAGCTTCCCGCGCTCGTCGCCACCGCCCGCACGCTCAACGACATCG
GCCCCCAGTTCTGA

Upstream 100 bases:

>100_bases
CGGCATCTCGGCCCGCGGCTCGGTCATCTGAGCGCCAGCGCTTTCCTGCGGCCGGCCCGCACCGGCCGCGTTCCTTCCCG
GCTCGCCCCAAGGACCGCTC

Downstream 100 bases:

>100_bases
GCCTTGAGAGACGCACCATGCATGTGACCACGAAGGACGGCATCCGCCTGCATGTGGAAGAGGCGGGCGAGGGCACCCCC
ATCCTCTTCGTCCATGAGTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSSASQRNRYFDALSSTPGLMWLGQNTNHIPAHPAVKAAMIAAIEEGAFNAYAPPLGFEALRAAIVADLGTPGAEALVTE
GGVSALAMVCRAYCRPGTTFVTTDPTWKWPCLFAKQAGAEVIEIPIYDPACNYRLTPEALKAAVDERTAIIYLVDPNNPL
GIRYTREEIEAFAAIARDCGAMLVHDCTYRDFADGHYPALLAAPEGAIVSLSFSKWLGLAGLRVGALVAAPAVLEACAER
ATSVLGASVIAQRAAEAGLKVKPEWMGEVRRIDRANKAKIKEAASAIEGFALPVYPSHGNFLVLETIGAGIRPEALVEAA
RREKMMIRQGTYHTARFGDRFVKVSTSVPEGWVDAFCAQLPALVATARTLNDIGPQF

Sequences:

>Translated_377_residues
MSSASQRNRYFDALSSTPGLMWLGQNTNHIPAHPAVKAAMIAAIEEGAFNAYAPPLGFEALRAAIVADLGTPGAEALVTE
GGVSALAMVCRAYCRPGTTFVTTDPTWKWPCLFAKQAGAEVIEIPIYDPACNYRLTPEALKAAVDERTAIIYLVDPNNPL
GIRYTREEIEAFAAIARDCGAMLVHDCTYRDFADGHYPALLAAPEGAIVSLSFSKWLGLAGLRVGALVAAPAVLEACAER
ATSVLGASVIAQRAAEAGLKVKPEWMGEVRRIDRANKAKIKEAASAIEGFALPVYPSHGNFLVLETIGAGIRPEALVEAA
RREKMMIRQGTYHTARFGDRFVKVSTSVPEGWVDAFCAQLPALVATARTLNDIGPQF
>Mature_376_residues
SSASQRNRYFDALSSTPGLMWLGQNTNHIPAHPAVKAAMIAAIEEGAFNAYAPPLGFEALRAAIVADLGTPGAEALVTEG
GVSALAMVCRAYCRPGTTFVTTDPTWKWPCLFAKQAGAEVIEIPIYDPACNYRLTPEALKAAVDERTAIIYLVDPNNPLG
IRYTREEIEAFAAIARDCGAMLVHDCTYRDFADGHYPALLAAPEGAIVSLSFSKWLGLAGLRVGALVAAPAVLEACAERA
TSVLGASVIAQRAAEAGLKVKPEWMGEVRRIDRANKAKIKEAASAIEGFALPVYPSHGNFLVLETIGAGIRPEALVEAAR
REKMMIRQGTYHTARFGDRFVKVSTSVPEGWVDAFCAQLPALVATARTLNDIGPQF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=356, Percent_Identity=24.438202247191, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40333; Mature: 40201

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASQRNRYFDALSSTPGLMWLGQNTNHIPAHPAVKAAMIAAIEEGAFNAYAPPLGFEA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
LRAAIVADLGTPGAEALVTEGGVSALAMVCRAYCRPGTTFVTTDPTWKWPCLFAKQAGAE
HHHHHHHHCCCCCCHHHEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHCCCC
VIEIPIYDPACNYRLTPEALKAAVDERTAIIYLVDPNNPLGIRYTREEIEAFAAIARDCG
EEEEECCCCCCCCEECHHHHHHHHCCCEEEEEEECCCCCCCEEECHHHHHHHHHHHHHHH
AMLVHDCTYRDFADGHYPALLAAPEGAIVSLSFSKWLGLAGLRVGALVAAPAVLEACAER
HHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATSVLGASVIAQRAAEAGLKVKPEWMGEVRRIDRANKAKIKEAASAIEGFALPVYPSHGN
HHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCC
FLVLETIGAGIRPEALVEAARREKMMIRQGTYHTARFGDRFVKVSTSVPEGWVDAFCAQL
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCHHHHHHHHHHH
PALVATARTLNDIGPQF
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSASQRNRYFDALSSTPGLMWLGQNTNHIPAHPAVKAAMIAAIEEGAFNAYAPPLGFEA
CCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
LRAAIVADLGTPGAEALVTEGGVSALAMVCRAYCRPGTTFVTTDPTWKWPCLFAKQAGAE
HHHHHHHHCCCCCCHHHEECCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHCCCC
VIEIPIYDPACNYRLTPEALKAAVDERTAIIYLVDPNNPLGIRYTREEIEAFAAIARDCG
EEEEECCCCCCCCEECHHHHHHHHCCCEEEEEEECCCCCCCEEECHHHHHHHHHHHHHHH
AMLVHDCTYRDFADGHYPALLAAPEGAIVSLSFSKWLGLAGLRVGALVAAPAVLEACAER
HHHHHCCCCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATSVLGASVIAQRAAEAGLKVKPEWMGEVRRIDRANKAKIKEAASAIEGFALPVYPSHGN
HHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCC
FLVLETIGAGIRPEALVEAARREKMMIRQGTYHTARFGDRFVKVSTSVPEGWVDAFCAQL
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCHHHHHHHHHHH
PALVATARTLNDIGPQF
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]