BacMap

Definition	Azorhizobium caulinodans ORS 571, complete genome.
Accession	NC_009937
Length	5,369,772

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The map label for this gene is fabG [H]

Identifier: 158424067

GI number: 158424067

Start: 2779141

End: 2779920

Strand: Reverse

Name: fabG [H]

Synonym: AZC_2443

Alternate gene names: 158424067

Gene position: 2779920-2779141 (Counterclockwise)

Preceding gene: 158424068

Following gene: 158424066

Centisome position: 51.77

GC content: 64.87

Gene sequence:

>780_bases
TTGAAGTTGGACCTCACGAACAAGACCGCCCTGATCACCGGCGCCTCGAAGGGCATCGGCCTTGCGGTGGCACAGGTGTT
TGCTGCCGAGGGCTGCCACCTGCATCTGGCCGCCCGCAATGGCGAGGCGATGGCGCAGGCCAAGAGCGAGCTGGAAGCCG
CCCACGGCGTGCGCGTTACCGTGCATGCGCTCGATCTGTCGTCCACCGAGGCCATGGAGAAGCTGGCCGAGGACGTGGGC
TATGTGGACATTCTGATCAACAATGCCGGCGACATCCCTGCCGGCTCGCTGGAGATCGTGGACGATGCCGCCTGGCGGCG
CGGCTTCGATCTCAAGGTCTTCGGCTACATCACGCTGGCCCGCGCCTTCTATAAGAAGATGCGCGGCAAGGATGGCGTGA
TCGTCAATGTCATCGGCAATTCCGGCGAGAACTGGGATGCGAGCTATATCGCCGGCTCCACCGGCAATGCCGCGCTCATG
TCCTTCACCAAGGCGCTCGGCGGCGCGAGCCTCAATGAGGGCGTGCGCGTGGTGGGCGTCAATCCGGGGCCGGTGGCGAC
GGATCGCATGCTCAAGATCATGAAGCGCAAGGCCATCGACATGCTGGGCGATGAAAGCCGCTGGGAGGAGCTGTTCGACA
AATATCCGGGCAAGCGGCCCGCGACCTCCGAGGAAGTGGCGGACCTCGTCGCCTTCCTCGCTTCGCCCCGCGCCGGCTAC
ATCACCGGCACCAACGTGACCATCGATGGCGGCATCTCGGCCCGCGGCTCGGTCATCTGA

Upstream 100 bases:

>100_bases
ATTTGCTGGATTTCCTCGCCGCCTTTGGATGAGCGCGAGTGAGGCAAGTTGGTATGCAATTTGCTAGCTATTGTATATCC
ATTTCGCCCGGAGACCTGCC

Downstream 100 bases:

>100_bases
GCGCCAGCGCTTTCCTGCGGCCGGCCCGCACCGGCCGCGTTCCTTCCCGGCTCGCCCCAAGGACCGCTCATGTCATCCGC
CAGCCAGCGCAATCGCTATT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKLDLTNKTALITGASKGIGLAVAQVFAAEGCHLHLAARNGEAMAQAKSELEAAHGVRVTVHALDLSSTEAMEKLAEDVG
YVDILINNAGDIPAGSLEIVDDAAWRRGFDLKVFGYITLARAFYKKMRGKDGVIVNVIGNSGENWDASYIAGSTGNAALM
SFTKALGGASLNEGVRVVGVNPGPVATDRMLKIMKRKAIDMLGDESRWEELFDKYPGKRPATSEEVADLVAFLASPRAGY
ITGTNVTIDGGISARGSVI

Sequences:

>Translated_259_residues
MKLDLTNKTALITGASKGIGLAVAQVFAAEGCHLHLAARNGEAMAQAKSELEAAHGVRVTVHALDLSSTEAMEKLAEDVG
YVDILINNAGDIPAGSLEIVDDAAWRRGFDLKVFGYITLARAFYKKMRGKDGVIVNVIGNSGENWDASYIAGSTGNAALM
SFTKALGGASLNEGVRVVGVNPGPVATDRMLKIMKRKAIDMLGDESRWEELFDKYPGKRPATSEEVADLVAFLASPRAGY
ITGTNVTIDGGISARGSVI
>Mature_259_residues
MKLDLTNKTALITGASKGIGLAVAQVFAAEGCHLHLAARNGEAMAQAKSELEAAHGVRVTVHALDLSSTEAMEKLAEDVG
YVDILINNAGDIPAGSLEIVDDAAWRRGFDLKVFGYITLARAFYKKMRGKDGVIVNVIGNSGENWDASYIAGSTGNAALM
SFTKALGGASLNEGVRVVGVNPGPVATDRMLKIMKRKAIDMLGDESRWEELFDKYPGKRPATSEEVADLVAFLASPRAGY
ITGTNVTIDGGISARGSVI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=28.0769230769231, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=30.2681992337165, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=27.0916334661355, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI66933014, Length=229, Percent_Identity=29.2576419213974, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=26.5625, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7657478, Length=236, Percent_Identity=30.5084745762712, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=26.7175572519084, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=33.7254901960784, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=35.546875, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787905, Length=262, Percent_Identity=25.9541984732824, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=27.6515151515151, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=25, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=24.8062015503876, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=27.6264591439689, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=32.8413284132841, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=29.1187739463602, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=28.8537549407115, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=29.0441176470588, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.968253968254, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=29.8039215686275, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=27.5471698113208, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=28.7937743190661, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=29.2307692307692, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=28.8321167883212, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.8507462686567, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=277, Percent_Identity=28.158844765343, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=28.740157480315, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=25.187969924812, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=25.9541984732824, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=284, Percent_Identity=29.2253521126761, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=28.1021897810219, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=25.6505576208178, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.6932270916335, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=279, Percent_Identity=27.2401433691756, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=24.812030075188, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.3408239700375, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=255, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=32.6693227091633, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=33.587786259542, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=29.718875502008, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=28.5140562248996, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=28.0632411067194, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=28.740157480315, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=30.5343511450382, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=207, Percent_Identity=30.4347826086957, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27329; Mature: 27329

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDLTNKTALITGASKGIGLAVAQVFAAEGCHLHLAARNGEAMAQAKSELEAAHGVRVT
CEECCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEE
VHALDLSSTEAMEKLAEDVGYVDILINNAGDIPAGSLEIVDDAAWRRGFDLKVFGYITLA
EEEECCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEHHHHHCCCCEEHHHHHHHH
RAFYKKMRGKDGVIVNVIGNSGENWDASYIAGSTGNAALMSFTKALGGASLNEGVRVVGV
HHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEC
NPGPVATDRMLKIMKRKAIDMLGDESRWEELFDKYPGKRPATSEEVADLVAFLASPRAGY
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
ITGTNVTIDGGISARGSVI
EECCCEEECCCCCCCCCCC
>Mature Secondary Structure
MKLDLTNKTALITGASKGIGLAVAQVFAAEGCHLHLAARNGEAMAQAKSELEAAHGVRVT
CEECCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEE
VHALDLSSTEAMEKLAEDVGYVDILINNAGDIPAGSLEIVDDAAWRRGFDLKVFGYITLA
EEEECCCCHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEHHHHHCCCCEEHHHHHHHH
RAFYKKMRGKDGVIVNVIGNSGENWDASYIAGSTGNAALMSFTKALGGASLNEGVRVVGV
HHHHHHHCCCCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEC
NPGPVATDRMLKIMKRKAIDMLGDESRWEELFDKYPGKRPATSEEVADLVAFLASPRAGY
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
ITGTNVTIDGGISARGSVI
EECCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1556094; 8905232; 9278503; 1314802 [H]