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The map label for this gene is acoC [H]

Identifier: 158423531

GI number: 158423531

Start: 2185099

End: 2186214

Strand: Reverse

Name: acoC [H]

Synonym: AZC_1907

Alternate gene names: 158423531

Gene position: 2186214-2185099 (Counterclockwise)

Preceding gene: 158423532

Following gene: 158423530

Centisome position: 40.71

GC content: 68.1

Gene sequence:

>1116_bases
ATGAACGCGCGTATCAATCCCATTGTCATGCCCAAGTGGGGGCTCTCCATGGCGGAGGGCAAGGTGACGGGCTGGCTCGT
CCGGCCTGGCGCGAAGATCACCGCCGGCGACGAGATCCTCGAAGTTGAGACGGACAAGATTGCCGGGGTGGTCGAAGCCG
GCGAGGCCGGCACTCTGCGGCGCGTCCTCGGCGAGCCCCAGACGGTCTATCCCGTGAAGGCGCTCATCGGCGTCATCGCG
GACGATGATGTGCCCGATGCGGAGATCGACGCCTTTGTCGCCGCTTATGCCGTGCCTGCCGAGGAGGGGGAGGACGCCGC
GGAGGCCGGGCCACGCTATGAATTCGTCGAAACGCCGGCCGGGCGCCTGCGCTATGCCCGCCGCGGCGAGGGCGAGGATA
CGGTACTGCTGATCCACGGCTTCGGCGGCGATCTCGACAACTGGCTGTTCAATATCGACGCTTTGGGCGCCGCCGCCACC
GTCTATGCCCTCGATCTTCCGGGCCATGGGCAATCGGAGAAGGCGCTCGGCGACCCCAGCCTGCCGGGCCTCGCGACGGC
CGTGCTCGGCTTCATGGATGCCCTCGGCATCGCGCGCGCCCATCTGGTGGGCCATTCCATGGGCGGCGCGCTCGCCCAGC
GGGTGGCGGTCGATGCGCCGTCCCGTGTGGCCTCGATTGCCCTCATTGCATCGGCCGGGCTCGGGCCGGAGATCAATGGC
GATTACATCGCCGGCTTCGTTTCGGCCGCCGGACGGCGTGAGCTCAAGCCCGTGCTGGAACATCTCTTCCACGACCCGTC
CACCGTGACGCGGCAGTTGGTGGACGACGTGCTGAAATACAAGCGCATCGATGGTGTCGATACGGCCCTGCGGGCGCTTG
CGGACGGCCTCTTTCCCGATGGCCGGCAGGCCAGCCAGCTCGCCGACCGGACACGCGCAGCGGGGACACGCACGCTCGTC
GTCTTCGGCGAGGGCGACCGCATCATTCCCGCCGCCCACGCTCAGGCGCTCGCGGACACTGCGCAGGTGCATGTACTGCC
GGAGGCCGGGCACATGGTGCAGATGGAAAAGGCCGGGCGGGTCAACGAACTCCTGCTCAAGCACATCGCCGGCTGA

Upstream 100 bases:

>100_bases
CCGGGACGCCTCAGGGCGGTCCCGGCCACCATCCAGAGCTTCAGCTTCAAACCGGCACCGGCCGCACAGACACGCGGGCC
CGGCGCCGAGGGAGACAGGA

Downstream 100 bases:

>100_bases
CCGGCTTTTCTCCCCTCTCCAGAAACAAGGCGCCGTCCGACCCAGGACGGCCAAGGAGGACCCATGCCCAATCTCCAGAA
CAAGTCGATCGTCATCACCG

Product: branched-chain alpha-keto acid dehydrogenase subunit E2

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system; Fast-migrating protein; FMP [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MNARINPIVMPKWGLSMAEGKVTGWLVRPGAKITAGDEILEVETDKIAGVVEAGEAGTLRRVLGEPQTVYPVKALIGVIA
DDDVPDAEIDAFVAAYAVPAEEGEDAAEAGPRYEFVETPAGRLRYARRGEGEDTVLLIHGFGGDLDNWLFNIDALGAAAT
VYALDLPGHGQSEKALGDPSLPGLATAVLGFMDALGIARAHLVGHSMGGALAQRVAVDAPSRVASIALIASAGLGPEING
DYIAGFVSAAGRRELKPVLEHLFHDPSTVTRQLVDDVLKYKRIDGVDTALRALADGLFPDGRQASQLADRTRAAGTRTLV
VFGEGDRIIPAAHAQALADTAQVHVLPEAGHMVQMEKAGRVNELLLKHIAG

Sequences:

>Translated_371_residues
MNARINPIVMPKWGLSMAEGKVTGWLVRPGAKITAGDEILEVETDKIAGVVEAGEAGTLRRVLGEPQTVYPVKALIGVIA
DDDVPDAEIDAFVAAYAVPAEEGEDAAEAGPRYEFVETPAGRLRYARRGEGEDTVLLIHGFGGDLDNWLFNIDALGAAAT
VYALDLPGHGQSEKALGDPSLPGLATAVLGFMDALGIARAHLVGHSMGGALAQRVAVDAPSRVASIALIASAGLGPEING
DYIAGFVSAAGRRELKPVLEHLFHDPSTVTRQLVDDVLKYKRIDGVDTALRALADGLFPDGRQASQLADRTRAAGTRTLV
VFGEGDRIIPAAHAQALADTAQVHVLPEAGHMVQMEKAGRVNELLLKHIAG
>Mature_371_residues
MNARINPIVMPKWGLSMAEGKVTGWLVRPGAKITAGDEILEVETDKIAGVVEAGEAGTLRRVLGEPQTVYPVKALIGVIA
DDDVPDAEIDAFVAAYAVPAEEGEDAAEAGPRYEFVETPAGRLRYARRGEGEDTVLLIHGFGGDLDNWLFNIDALGAAAT
VYALDLPGHGQSEKALGDPSLPGLATAVLGFMDALGIARAHLVGHSMGGALAQRVAVDAPSRVASIALIASAGLGPEING
DYIAGFVSAAGRRELKPVLEHLFHDPSTVTRQLVDDVLKYKRIDGVDTALRALADGLFPDGRQASQLADRTRAAGTRTLV
VFGEGDRIIPAAHAQALADTAQVHVLPEAGHMVQMEKAGRVNELLLKHIAG

Specific function: Dihydrolipoamide acetyltransferase involved in acetoin catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI189027141, Length=285, Percent_Identity=24.5614035087719, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI87081721, Length=271, Percent_Identity=26.5682656826568, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 38954; Mature: 38954

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARINPIVMPKWGLSMAEGKVTGWLVRPGAKITAGDEILEVETDKIAGVVEAGEAGTLR
CCCCCCCEEECCCCCCCCCCCEEEEEECCCCEEECCCCEEEEEHHHHHHEEECCCCHHHH
RVLGEPQTVYPVKALIGVIADDDVPDAEIDAFVAAYAVPAEEGEDAAEAGPRYEFVETPA
HHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCH
GRLRYARRGEGEDTVLLIHGFGGDLDNWLFNIDALGAAATVYALDLPGHGQSEKALGDPS
HHHHHHHCCCCCCEEEEEECCCCCHHHHEEEHHHHCCEEEEEEEECCCCCCCCCCCCCCC
LPGLATAVLGFMDALGIARAHLVGHSMGGALAQRVAVDAPSRVASIALIASAGLGPEING
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
DYIAGFVSAAGRRELKPVLEHLFHDPSTVTRQLVDDVLKYKRIDGVDTALRALADGLFPD
HHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
GRQASQLADRTRAAGTRTLVVFGEGDRIIPAAHAQALADTAQVHVLPEAGHMVQMEKAGR
CCHHHHHHHHHHCCCCEEEEEECCCCEEECHHHHHHHHCCCEEEEEECCCCEEEEHHCCC
VNELLLKHIAG
HHHHHHHHHCC
>Mature Secondary Structure
MNARINPIVMPKWGLSMAEGKVTGWLVRPGAKITAGDEILEVETDKIAGVVEAGEAGTLR
CCCCCCCEEECCCCCCCCCCCEEEEEECCCCEEECCCCEEEEEHHHHHHEEECCCCHHHH
RVLGEPQTVYPVKALIGVIADDDVPDAEIDAFVAAYAVPAEEGEDAAEAGPRYEFVETPA
HHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCH
GRLRYARRGEGEDTVLLIHGFGGDLDNWLFNIDALGAAATVYALDLPGHGQSEKALGDPS
HHHHHHHCCCCCCEEEEEECCCCCHHHHEEEHHHHCCEEEEEEEECCCCCCCCCCCCCCC
LPGLATAVLGFMDALGIARAHLVGHSMGGALAQRVAVDAPSRVASIALIASAGLGPEING
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
DYIAGFVSAAGRRELKPVLEHLFHDPSTVTRQLVDDVLKYKRIDGVDTALRALADGLFPD
HHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
GRQASQLADRTRAAGTRTLVVFGEGDRIIPAAHAQALADTAQVHVLPEAGHMVQMEKAGR
CCHHHHHHHHHHCCCCEEEEEECCCCEEECHHHHHHHHCCCEEEEEECCCCEEEEHHCCC
VNELLLKHIAG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2061286 [H]