BacMap

Definition	Azorhizobium caulinodans ORS 571, complete genome.
Accession	NC_009937
Length	5,369,772

Click here to switch to the map view.

The map label for this gene is butA [H]

Identifier: 158423530

GI number: 158423530

Start: 2184250

End: 2185035

Strand: Reverse

Name: butA [H]

Synonym: AZC_1906

Alternate gene names: 158423530

Gene position: 2185035-2184250 (Counterclockwise)

Preceding gene: 158423531

Following gene: 158423528

Centisome position: 40.69

GC content: 66.54

Gene sequence:

>786_bases
ATGCCCAATCTCCAGAACAAGTCGATCGTCATCACCGGCGCCGCCGGCGGCATTGGCGCCGCCATCGCCAAGGCGCTGGC
GGCCGATGGCGCACGCATCCTCGTGGCTGACCTTTCAGAAGAGGCCGCGAACCGGGTGGCAGGCGAGATCACCGCCGCCG
GAGGAACCGCAAAGGCAATCGCCGTGGACGTCCGCCGCCGCGCCGATGTGCGCGCCATGATCGATGCGGCGGTGTCCGCT
TTCGGGCGCCTCGACGTTCTCTTCAACAATGCCGGTGTCGCCCAGACGCGCCCTTTCCTCGACATCACCGAGGACGACTG
GCACTTCGTCACCGATGTGAATGCCATGGGCGTGCTGATCGGCATGCAGGAAGCCGTCAAGACCTTCCGCGCCCAGGGCG
GTGGCGGCAAGATCATCAACACTGCGTCCATCGCCGGCAAGCAGGGCTATGAGCCGCTCGCGCATTATTCCGCCAGCAAG
TTCGCGGTCGTGGCGCTCACCCAGGCAGCCGCCCGCGCCTTCGGCAAGGAGGGCATCACGGCCAATGCCTTCTGCCCGGG
CGTGGTCGCCACCGACATGTGGAAGACCATCGACAAGGGGTTCCGCGACAGCGGCCTGACGCACAAGGAAAACGAAGCCT
TCGATGGCTTTGCTGCCGGTGCCCTGCTGGGCCGGGCCTCGCGTCCGGACGATCTGGTGGGCGTCGCGCGCTTCCTCGCC
TCGTCCGACTCCGATTTCATGACCGGCCAGTCGCTGCTGGTGGATGGCGGGATGGTCCTCGTCTGA

Upstream 100 bases:

>100_bases
GGTCAACGAACTCCTGCTCAAGCACATCGCCGGCTGACCGGCTTTTCTCCCCTCTCCAGAAACAAGGCGCCGTCCGACCC
AGGACGGCCAAGGAGGACCC

Downstream 100 bases:

>100_bases
GGAAAACCGCGCGCCGCCGTCCAGCGGCGGCGCGTCACAATTCTTCCAGGCTATCCCCGATGGCCTCGATGCCGCGCAGC
CGCTTGCGCCCCGCTGCGCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: Acetoin(diacetyl) reductase; AR; Meso-2,3-butanediol dehydrogenase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MPNLQNKSIVITGAAGGIGAAIAKALAADGARILVADLSEEAANRVAGEITAAGGTAKAIAVDVRRRADVRAMIDAAVSA
FGRLDVLFNNAGVAQTRPFLDITEDDWHFVTDVNAMGVLIGMQEAVKTFRAQGGGGKIINTASIAGKQGYEPLAHYSASK
FAVVALTQAAARAFGKEGITANAFCPGVVATDMWKTIDKGFRDSGLTHKENEAFDGFAAGALLGRASRPDDLVGVARFLA
SSDSDFMTGQSLLVDGGMVLV

Sequences:

>Translated_261_residues
MPNLQNKSIVITGAAGGIGAAIAKALAADGARILVADLSEEAANRVAGEITAAGGTAKAIAVDVRRRADVRAMIDAAVSA
FGRLDVLFNNAGVAQTRPFLDITEDDWHFVTDVNAMGVLIGMQEAVKTFRAQGGGGKIINTASIAGKQGYEPLAHYSASK
FAVVALTQAAARAFGKEGITANAFCPGVVATDMWKTIDKGFRDSGLTHKENEAFDGFAAGALLGRASRPDDLVGVARFLA
SSDSDFMTGQSLLVDGGMVLV
>Mature_260_residues
PNLQNKSIVITGAAGGIGAAIAKALAADGARILVADLSEEAANRVAGEITAAGGTAKAIAVDVRRRADVRAMIDAAVSAF
GRLDVLFNNAGVAQTRPFLDITEDDWHFVTDVNAMGVLIGMQEAVKTFRAQGGGGKIINTASIAGKQGYEPLAHYSASKF
AVVALTQAAARAFGKEGITANAFCPGVVATDMWKTIDKGFRDSGLTHKENEAFDGFAAGALLGRASRPDDLVGVARFLAS
SDSDFMTGQSLLVDGGMVLV

Specific function: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=8e-30,
Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=26.9230769230769, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=29.0076335877863, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=31.4176245210728, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI31542939, Length=199, Percent_Identity=34.1708542713568, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI40254992, Length=256, Percent_Identity=28.515625, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=26.0700389105058, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=30.1255230125523, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI109715829, Length=258, Percent_Identity=27.1317829457364, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=23.4615384615385, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=28.3464566929134, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=32.7683615819209, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI210032110, Length=218, Percent_Identity=25.2293577981651, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4758504, Length=201, Percent_Identity=32.8358208955224, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=27.8625954198473, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI166795268, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI10190746, Length=220, Percent_Identity=27.7272727272727, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=26.7379679144385, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40254986, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI225579078, Length=204, Percent_Identity=28.921568627451, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI83715985, Length=181, Percent_Identity=34.2541436464088, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40807363, Length=202, Percent_Identity=26.7326732673267, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=35.0194552529183, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=32.4324324324324, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=35.2490421455939, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=28.957528957529, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=31.3492063492063, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=31.5175097276265, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=31.3953488372093, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=29.4573643410853, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=28.030303030303, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI2367365, Length=252, Percent_Identity=30.1587301587302, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI2367175, Length=189, Percent_Identity=32.8042328042328, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787820, Length=153, Percent_Identity=28.7581699346405, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=30.5882352941176, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.5555555555556, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=29.5454545454545, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=30.5454545454545, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=29.718875502008, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=28.7313432835821, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=29.7101449275362, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=28.8537549407115, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=285, Percent_Identity=28.4210526315789, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=25, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=34.3915343915344, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=31.2727272727273, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=29.5620437956204, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=275, Percent_Identity=28, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=273, Percent_Identity=27.8388278388278, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=28.7179487179487, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=277, Percent_Identity=28.8808664259928, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=28.2051282051282, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=28.6792452830189, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=27.9411764705882, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=276, Percent_Identity=28.6231884057971, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=28.5185185185185, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=26.9961977186312, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=26.1538461538462, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=264, Percent_Identity=28.7878787878788, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=29.2592592592593, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=279, Percent_Identity=28.673835125448, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=201, Percent_Identity=27.8606965174129, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=28.4263959390863, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=31.5533980582524, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=208, Percent_Identity=27.8846153846154, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=27.5735294117647, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=25.7731958762887, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=199, Percent_Identity=26.1306532663317, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=36.7875647668394, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=31.5589353612167, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571526, Length=266, Percent_Identity=32.3308270676692, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357041, Length=266, Percent_Identity=30.8270676691729, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=31.2741312741313, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=29.1828793774319, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644339, Length=267, Percent_Identity=29.2134831460674, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=35.0785340314136, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17737361, Length=214, Percent_Identity=33.1775700934579, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=31.1284046692607, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641232, Length=240, Percent_Identity=30.4166666666667, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=29.0155440414508, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281364494, Length=205, Percent_Identity=31.7073170731707, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=26.2886597938144, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=212, Percent_Identity=27.8301886792453, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=30.078125, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571387, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364892, Length=168, Percent_Identity=31.547619047619, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331218, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665243, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331216, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665247, Length=193, Percent_Identity=26.9430051813472, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580925, Length=201, Percent_Identity=30.8457711442786, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.304 [H]

Molecular weight: Translated: 26917; Mature: 26786

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLQNKSIVITGAAGGIGAAIAKALAADGARILVADLSEEAANRVAGEITAAGGTAKAI
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCEEEECCCCCEEE
AVDVRRRADVRAMIDAAVSAFGRLDVLFNNAGVAQTRPFLDITEDDWHFVTDVNAMGVLI
EEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEECCCCCEEEECCCHHHHHH
GMQEAVKTFRAQGGGGKIINTASIAGKQGYEPLAHYSASKFAVVALTQAAARAFGKEGIT
HHHHHHHHHHCCCCCCCEEEEHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
ANAFCPGVVATDMWKTIDKGFRDSGLTHKENEAFDGFAAGALLGRASRPDDLVGVARFLA
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
SSDSDFMTGQSLLVDGGMVLV
CCCCCCCCCCEEEECCCEEEC
>Mature Secondary Structure 
PNLQNKSIVITGAAGGIGAAIAKALAADGARILVADLSEEAANRVAGEITAAGGTAKAI
CCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCEEEECCCCCEEE
AVDVRRRADVRAMIDAAVSAFGRLDVLFNNAGVAQTRPFLDITEDDWHFVTDVNAMGVLI
EEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCEEECCCCCEEEECCCHHHHHH
GMQEAVKTFRAQGGGGKIINTASIAGKQGYEPLAHYSASKFAVVALTQAAARAFGKEGIT
HHHHHHHHHHCCCCCCCEEEEHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
ANAFCPGVVATDMWKTIDKGFRDSGLTHKENEAFDGFAAGALLGRASRPDDLVGVARFLA
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
SSDSDFMTGQSLLVDGGMVLV
CCCCCCCCCCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA