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The map label for this gene is aroC

Identifier: 158423373

GI number: 158423373

Start: 1999749

End: 2000864

Strand: Reverse

Name: aroC

Synonym: AZC_1749

Alternate gene names: 158423373

Gene position: 2000864-1999749 (Counterclockwise)

Preceding gene: 158423375

Following gene: 158423349

Centisome position: 37.26

GC content: 70.07

Gene sequence:

>1116_bases
ATGTCGTTCAACACGTTCGGGCACCTGTTCCGTGTCACCACCTTCGGCGAGAGCCATGGCCCGGCCATCGGCTGCGTGGT
GGACGGCTGCCCGCCCGGCCTGCGCTTTACCGTTGATGAGGTGCAGGCTGCGCTCGACCGGCGCCGGCCCGGCCAGTCGC
GCTTCACCACCCAGCGGCGCGAGCCGGACCAGGTGCGCGTCATCTCCGGCACCATGGACCATCCGGAGGGTGGCCTCGTC
ACCACCGGCACGCCCATCGGCCTGCTCATCGAGAATGTGGACCAGCGCTCCAAGGACTATGCCGACATCGCCGGCAGCTA
CCGCCCCGGCCATGCGGACGTGACCTATGACCTGAAATACGGCCTGCGGGACCATCGCGGCGGCGGGCGCTCCTCGGCCC
GCGAGACGGCCATGCGCGTCGCGGCCGGCGCCATCGCCGCCAAGGTACTGCCCGGCGTGACCGTGCGCGCCGCTCTCACC
CGTATCGGCGAGATCGAGATCGACCGCGCCCGCTGGGACTGGGCGCAGGTGAGCGAGAACCCCTTCTTCTGTCCGGACCC
GGAGACGGTGCCGGTGTGGACCGATTATCTCGACGGCATCCGCAAGCGCGGCTCGTCCGTCGGCGCGGTGATCGAAGTGG
TGGCGGAAGGCGTGCCGGCGGGCCTCGGCGCGCCCATCTACGGCAAGCTGGATGCGGACCTTGCCGCCGCCTTCATGAGC
ATCAATGCCGTGAAGGGCGTGGAGATCGGCGAGGGCTTCAACGCCGCCCGCCTCACCGGCGAGGAGAATGCGGACGAGAT
GCGCACCGGCAATGACGGCCGGCCGTATTTCCTCTCCAACCACGCCGGCGGCATCCTCGGCGGCATCTCCAGCGGCGAGC
CCGTGGTGGCGCGCTTCGCGGTGAAGCCCACCTCTTCCATCCTCACGCCCCGCCGGACGGTGGACAAGTTCGGCACCGAG
GAAGACCTCATCACCAAGGGCCGCCACGACCCCTGCGTCGGCATCCGCGCCGTGCCCGTTGGCGAAGCCATGATGCTGTG
CGTGTTGGCCGACCACCTCCTGCGCCATCGCGGGCAGGTCGGCACGACCCCCGTGTGGCCGTTCCAGCGGGGCTGA

Upstream 100 bases:

>100_bases
GTGCTTGTGGGCATGGCCATTGCGTTGCCAGCCCGGCGGCATCTGCTCTACAGAGCATCAACCGGCCCGCCGCGCGCCAA
TCTCTAGAGAAGCCAGCCTC

Downstream 100 bases:

>100_bases
TGCGGCGGCCCTGCCCATCACTGCATTGGGGCCACTCCTTCGCTCCCTCGGCCGTCATGCCCGGGCTTGTCCCGGGCATC
CACGCCGCGCCGACAGCACA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSFNTFGHLFRVTTFGESHGPAIGCVVDGCPPGLRFTVDEVQAALDRRRPGQSRFTTQRREPDQVRVISGTMDHPEGGLV
TTGTPIGLLIENVDQRSKDYADIAGSYRPGHADVTYDLKYGLRDHRGGGRSSARETAMRVAAGAIAAKVLPGVTVRAALT
RIGEIEIDRARWDWAQVSENPFFCPDPETVPVWTDYLDGIRKRGSSVGAVIEVVAEGVPAGLGAPIYGKLDADLAAAFMS
INAVKGVEIGEGFNAARLTGEENADEMRTGNDGRPYFLSNHAGGILGGISSGEPVVARFAVKPTSSILTPRRTVDKFGTE
EDLITKGRHDPCVGIRAVPVGEAMMLCVLADHLLRHRGQVGTTPVWPFQRG

Sequences:

>Translated_371_residues
MSFNTFGHLFRVTTFGESHGPAIGCVVDGCPPGLRFTVDEVQAALDRRRPGQSRFTTQRREPDQVRVISGTMDHPEGGLV
TTGTPIGLLIENVDQRSKDYADIAGSYRPGHADVTYDLKYGLRDHRGGGRSSARETAMRVAAGAIAAKVLPGVTVRAALT
RIGEIEIDRARWDWAQVSENPFFCPDPETVPVWTDYLDGIRKRGSSVGAVIEVVAEGVPAGLGAPIYGKLDADLAAAFMS
INAVKGVEIGEGFNAARLTGEENADEMRTGNDGRPYFLSNHAGGILGGISSGEPVVARFAVKPTSSILTPRRTVDKFGTE
EDLITKGRHDPCVGIRAVPVGEAMMLCVLADHLLRHRGQVGTTPVWPFQRG
>Mature_370_residues
SFNTFGHLFRVTTFGESHGPAIGCVVDGCPPGLRFTVDEVQAALDRRRPGQSRFTTQRREPDQVRVISGTMDHPEGGLVT
TGTPIGLLIENVDQRSKDYADIAGSYRPGHADVTYDLKYGLRDHRGGGRSSARETAMRVAAGAIAAKVLPGVTVRAALTR
IGEIEIDRARWDWAQVSENPFFCPDPETVPVWTDYLDGIRKRGSSVGAVIEVVAEGVPAGLGAPIYGKLDADLAAAFMSI
NAVKGVEIGEGFNAARLTGEENADEMRTGNDGRPYFLSNHAGGILGGISSGEPVVARFAVKPTSSILTPRRTVDKFGTEE
DLITKGRHDPCVGIRAVPVGEAMMLCVLADHLLRHRGQVGTTPVWPFQRG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=362, Percent_Identity=62.1546961325967, Blast_Score=424, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=42.627345844504, Blast_Score=273, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_AZOC5 (A8I4M5)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524665.1
- ProteinModelPortal:   A8I4M5
- SMR:   A8I4M5
- GeneID:   5688189
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1749
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- BioCyc:   ACAU438753:AZC_1749-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39831; Mature: 39699

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNTFGHLFRVTTFGESHGPAIGCVVDGCPPGLRFTVDEVQAALDRRRPGQSRFTTQRR
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCHHHCCCCC
EPDQVRVISGTMDHPEGGLVTTGTPIGLLIENVDQRSKDYADIAGSYRPGHADVTYDLKY
CCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEEC
GLRDHRGGGRSSARETAMRVAAGAIAAKVLPGVTVRAALTRIGEIEIDRARWDWAQVSEN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCHHHHCCC
PFFCPDPETVPVWTDYLDGIRKRGSSVGAVIEVVAEGVPAGLGAPIYGKLDADLAAAFMS
CCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
INAVKGVEIGEGFNAARLTGEENADEMRTGNDGRPYFLSNHAGGILGGISSGEPVVARFA
HHHHCCCCCCCCCCCEEECCCCCHHHHHCCCCCCCEEECCCCCCEEECCCCCCCEEEEEE
VKPTSSILTPRRTVDKFGTEEDLITKGRHDPCVGIRAVPVGEAMMLCVLADHLLRHRGQV
ECCCHHHCCCHHHHHHCCCCHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCC
GTTPVWPFQRG
CCCCCCCCCCC
>Mature Secondary Structure 
SFNTFGHLFRVTTFGESHGPAIGCVVDGCPPGLRFTVDEVQAALDRRRPGQSRFTTQRR
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCHHHCCCCC
EPDQVRVISGTMDHPEGGLVTTGTPIGLLIENVDQRSKDYADIAGSYRPGHADVTYDLKY
CCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEEC
GLRDHRGGGRSSARETAMRVAAGAIAAKVLPGVTVRAALTRIGEIEIDRARWDWAQVSEN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCHHHHCCC
PFFCPDPETVPVWTDYLDGIRKRGSSVGAVIEVVAEGVPAGLGAPIYGKLDADLAAAFMS
CCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
INAVKGVEIGEGFNAARLTGEENADEMRTGNDGRPYFLSNHAGGILGGISSGEPVVARFA
HHHHCCCCCCCCCCCEEECCCCCHHHHHCCCCCCCEEECCCCCCEEECCCCCCCEEEEEE
VKPTSSILTPRRTVDKFGTEEDLITKGRHDPCVGIRAVPVGEAMMLCVLADHLLRHRGQV
ECCCHHHCCCHHHHHHCCCCHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCC
GTTPVWPFQRG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA