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The map label for this gene is recG [H]

Identifier: 158423349

GI number: 158423349

Start: 1973455

End: 1975551

Strand: Reverse

Name: recG [H]

Synonym: AZC_1725

Alternate gene names: 158423349

Gene position: 1975551-1973455 (Counterclockwise)

Preceding gene: 158423373

Following gene: 158423348

Centisome position: 36.79

GC content: 71.2

Gene sequence:

>2097_bases
ATGCGCCCGGCTTTGCTCGATCCGCTTTTCGCCCCCCTCACCACGCTTCCCGGCATCGGGCCGAAGATGGTGCGCCCGTT
CGGGCGGCTGCTGGGGCGGGAAAATCCGCGCGTCATCGACCTCCTCTTCCACATGCCCTCCGGCCTCATCGACCGCCGGG
CGCGGCCGACCATCTTCGAGGCCGAGCCGGAAACGGACGTGACGCTGGAAGTGCGCGTGGACGGCCACAGCGCCCCGCCC
CCCGGCCGGCGCGCGCCGCATCGGACCTTCGTTTCGGACGCCAGCGGCGACCTGACGGTGGTCCATTTCAACATCGAACG
CGCCCGCATCGAGCGCCTGCTGCCCGTGGGCGAGACGCGCTGGCTGTGCGGGCGCGTGACGCTCTATGACGGCATGCGGC
AGATGACCCATCCCGACCGCATCCTCGATGCGGCAGGCCTCGCCAAGCTGCCGCCGGTGGAACCTAAATATCCGCTGACC
GAAGGCCTCGCCGGCGGCCATGTGCGTCGCGCCATGGAGGCCGCGCTCGCCCGCGTGCCCGAGTTGCCGGAGGCCATTCC
GCCGGAGCTTCTGGAGCGGGGCGACTGGCCCTCCTTCCGCGAGGCTCTGAAGCGCATCCACCAGCCCGAGACCCCGGTGG
ACGGCCTGCCCACCGGCCGGGCCTGGGAGCGCCTCGCCTTCGATGAGCTCTATGCCCATCAGGTGACGCTCGCCCTCGTG
CGGCAGACGCAGGTGAAGGCCGGCGGGCGGCCGACGCGCGGCGACGGACGGCTCGCCGCCGCCATCCTCAAGGCCCTGCC
CTTCCGCCTCACCAGCGCGCAGGAAGAGGCGCTCGCCGCCATCCGCGCCGATCTTGCGGCGGACACGCGGATGCTGCGCC
TGCTGCAAGGCGACGTGGGCTCGGGCAAGACCGTGGTGGCGCTTCTGGCTGCCGCCGCAGCCATCGAGGCCGGCCGTCAG
GCGGCGCTGATGGCGCCCACCGAAATCCTCGCCCGCCAGCATCTGGAGACCATCGCGCCGCTGGCGGCCGCCGCCGGCAT
CGAGGTGGCGGTGCTCACCGGCCGCGAGAAGGGGCGCACCCGCGCCGGCATTCTGGAGGGGCTCGCCAGCGGGCGCATCG
GACTCGTTGTGGGCACGCACGCGCTCATTCAGGACGATGTGGCCTTCGCTGATCTTGCCCTCGCCATCGTGGACGAGCAG
CACCGTTTCGGCGTCGAGCAGCGCCTCACTTTCTCCCGCAAGGGGGCGGCGGTGGACATGCTGCTGATGACGGCAACGCC
CATCCCCCGCACCCTCGTCCTCACCCTGTTCGGCGACATGGACAGTTCCGAGCTGCGGGAGAAGCCGCCGGGCCGCAAGC
CGGTGGACACACGCTCCGTCTCGCTGGAGCGTCTGGACGAAGTGGTCGGCGCCCTCGGCCGACAGTTGCGCGACGGGGCA
CAGGCCTACTGGATCTGCCCGCTGGTGGAGGAAAGCGACACCTCGGACCTCGCCGCCGCCACCGAGCGCGCCGCACATCT
GAAGAAGGTGTTCGGCGAAAAGGCGGTGGAACTGGTGCACGGACGCATGTCCGGCGCCGACAAGGACGCCGCCATGGCAC
GCTTTGCCTCAGGCGAGGCGCGCATTCTCGTCGCCACCACGGTGGTGGAGGTGGGCGTCAACGTGCCCAACGCCACGCTC
ATGGTGATCGAGCATGCGGAGCGCTTCGGCCTCGCCCAGCTCCACCAGTTGCGCGGGCGCGTCGGGCGCGGCGAGAAGGC
CTCGACATGCCTGCTGCTCTTTCGCGGCCCCCTGAGCGAGACCTCCAAGGCCCGCCTCGCCATCCTGCGCGAGAGCGAGG
ACGGCTTCCGCATCGCCGAGGAAGACCTGCGCCTGCGCGGCGAGGGCGACGTGCTCGGCACCAAGCAGAGCGGCCTGCCC
GGCTTCAAGGTGGCGCGCATGGAGGTGCATGGCGCCCTCGTCTCGCAGGCCCGCGATGCCGCCGCGCGTCTGGTGCCCGG
CAATCCCGATCTCGAAGGCCCCGAAGGCGAACGGGTGCGCACGCTGCTCTATGTGCAGGAGCGCGATGCGGCGGTGCGCT
TGCTCTCGGCCGGCTAA

Upstream 100 bases:

>100_bases
GGCGGGCGACGCCACTTGTTCCGGCAACTGAGCACCGCCCGCCCCCGCCCGAACGCCGCCGCTTGCCCGAATCCCCCCCA
TCCGCCACTTTCGGCGCCCC

Downstream 100 bases:

>100_bases
GGGGCCACCCTGCGCGCGATTACGTCGCCGCCCAAGGTTTCCTGCCCAGTGTCCACCGAGCCGCCGCGGCCCCCGTTCGC
CGCCGCCACCTTCCGCCAGA

Product: helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 698; Mature: 698

Protein sequence:

>698_residues
MRPALLDPLFAPLTTLPGIGPKMVRPFGRLLGRENPRVIDLLFHMPSGLIDRRARPTIFEAEPETDVTLEVRVDGHSAPP
PGRRAPHRTFVSDASGDLTVVHFNIERARIERLLPVGETRWLCGRVTLYDGMRQMTHPDRILDAAGLAKLPPVEPKYPLT
EGLAGGHVRRAMEAALARVPELPEAIPPELLERGDWPSFREALKRIHQPETPVDGLPTGRAWERLAFDELYAHQVTLALV
RQTQVKAGGRPTRGDGRLAAAILKALPFRLTSAQEEALAAIRADLAADTRMLRLLQGDVGSGKTVVALLAAAAAIEAGRQ
AALMAPTEILARQHLETIAPLAAAAGIEVAVLTGREKGRTRAGILEGLASGRIGLVVGTHALIQDDVAFADLALAIVDEQ
HRFGVEQRLTFSRKGAAVDMLLMTATPIPRTLVLTLFGDMDSSELREKPPGRKPVDTRSVSLERLDEVVGALGRQLRDGA
QAYWICPLVEESDTSDLAAATERAAHLKKVFGEKAVELVHGRMSGADKDAAMARFASGEARILVATTVVEVGVNVPNATL
MVIEHAERFGLAQLHQLRGRVGRGEKASTCLLLFRGPLSETSKARLAILRESEDGFRIAEEDLRLRGEGDVLGTKQSGLP
GFKVARMEVHGALVSQARDAAARLVPGNPDLEGPEGERVRTLLYVQERDAAVRLLSAG

Sequences:

>Translated_698_residues
MRPALLDPLFAPLTTLPGIGPKMVRPFGRLLGRENPRVIDLLFHMPSGLIDRRARPTIFEAEPETDVTLEVRVDGHSAPP
PGRRAPHRTFVSDASGDLTVVHFNIERARIERLLPVGETRWLCGRVTLYDGMRQMTHPDRILDAAGLAKLPPVEPKYPLT
EGLAGGHVRRAMEAALARVPELPEAIPPELLERGDWPSFREALKRIHQPETPVDGLPTGRAWERLAFDELYAHQVTLALV
RQTQVKAGGRPTRGDGRLAAAILKALPFRLTSAQEEALAAIRADLAADTRMLRLLQGDVGSGKTVVALLAAAAAIEAGRQ
AALMAPTEILARQHLETIAPLAAAAGIEVAVLTGREKGRTRAGILEGLASGRIGLVVGTHALIQDDVAFADLALAIVDEQ
HRFGVEQRLTFSRKGAAVDMLLMTATPIPRTLVLTLFGDMDSSELREKPPGRKPVDTRSVSLERLDEVVGALGRQLRDGA
QAYWICPLVEESDTSDLAAATERAAHLKKVFGEKAVELVHGRMSGADKDAAMARFASGEARILVATTVVEVGVNVPNATL
MVIEHAERFGLAQLHQLRGRVGRGEKASTCLLLFRGPLSETSKARLAILRESEDGFRIAEEDLRLRGEGDVLGTKQSGLP
GFKVARMEVHGALVSQARDAAARLVPGNPDLEGPEGERVRTLLYVQERDAAVRLLSAG
>Mature_698_residues
MRPALLDPLFAPLTTLPGIGPKMVRPFGRLLGRENPRVIDLLFHMPSGLIDRRARPTIFEAEPETDVTLEVRVDGHSAPP
PGRRAPHRTFVSDASGDLTVVHFNIERARIERLLPVGETRWLCGRVTLYDGMRQMTHPDRILDAAGLAKLPPVEPKYPLT
EGLAGGHVRRAMEAALARVPELPEAIPPELLERGDWPSFREALKRIHQPETPVDGLPTGRAWERLAFDELYAHQVTLALV
RQTQVKAGGRPTRGDGRLAAAILKALPFRLTSAQEEALAAIRADLAADTRMLRLLQGDVGSGKTVVALLAAAAAIEAGRQ
AALMAPTEILARQHLETIAPLAAAAGIEVAVLTGREKGRTRAGILEGLASGRIGLVVGTHALIQDDVAFADLALAIVDEQ
HRFGVEQRLTFSRKGAAVDMLLMTATPIPRTLVLTLFGDMDSSELREKPPGRKPVDTRSVSLERLDEVVGALGRQLRDGA
QAYWICPLVEESDTSDLAAATERAAHLKKVFGEKAVELVHGRMSGADKDAAMARFASGEARILVATTVVEVGVNVPNATL
MVIEHAERFGLAQLHQLRGRVGRGEKASTCLLLFRGPLSETSKARLAILRESEDGFRIAEEDLRLRGEGDVLGTKQSGLP
GFKVARMEVHGALVSQARDAAARLVPGNPDLEGPEGERVRTLLYVQERDAAVRLLSAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=662, Percent_Identity=42.4471299093656, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1787357, Length=403, Percent_Identity=36.4764267990074, Blast_Score=233, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 75485; Mature: 75485

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPALLDPLFAPLTTLPGIGPKMVRPFGRLLGRENPRVIDLLFHMPSGLIDRRARPTIFE
CCCCHHCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCCCHHHCCCCCCEEE
AEPETDVTLEVRVDGHSAPPPGRRAPHRTFVSDASGDLTVVHFNIERARIERLLPVGETR
CCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECHHHHHHHHCCCCCCC
WLCGRVTLYDGMRQMTHPDRILDAAGLAKLPPVEPKYPLTEGLAGGHVRRAMEAALARVP
CEEEEHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCC
ELPEAIPPELLERGDWPSFREALKRIHQPETPVDGLPTGRAWERLAFDELYAHQVTLALV
CCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQTQVKAGGRPTRGDGRLAAAILKALPFRLTSAQEEALAAIRADLAADTRMLRLLQGDVG
HHHHHHCCCCCCCCCCHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGKTVVALLAAAAAIEAGRQAALMAPTEILARQHLETIAPLAAAAGIEVAVLTGREKGRT
CCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
RAGILEGLASGRIGLVVGTHALIQDDVAFADLALAIVDEQHRFGVEQRLTFSRKGAAVDM
HHHHHHHHHCCCEEEEECCHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHHCCCCCCEEE
LLMTATPIPRTLVLTLFGDMDSSELREKPPGRKPVDTRSVSLERLDEVVGALGRQLRDGA
HEEECCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QAYWICPLVEESDTSDLAAATERAAHLKKVFGEKAVELVHGRMSGADKDAAMARFASGEA
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
RILVATTVVEVGVNVPNATLMVIEHAERFGLAQLHQLRGRVGRGEKASTCLLLFRGPLSE
EEEEEEEEHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
TSKARLAILRESEDGFRIAEEDLRLRGEGDVLGTKQSGLPGFKVARMEVHGALVSQARDA
CCCCEEEEEEECCCCCEEEHHHHEECCCCCEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
AARLVPGNPDLEGPEGERVRTLLYVQERDAAVRLLSAG
HHEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCC
>Mature Secondary Structure
MRPALLDPLFAPLTTLPGIGPKMVRPFGRLLGRENPRVIDLLFHMPSGLIDRRARPTIFE
CCCCHHCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHCCCCHHHCCCCCCEEE
AEPETDVTLEVRVDGHSAPPPGRRAPHRTFVSDASGDLTVVHFNIERARIERLLPVGETR
CCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECHHHHHHHHCCCCCCC
WLCGRVTLYDGMRQMTHPDRILDAAGLAKLPPVEPKYPLTEGLAGGHVRRAMEAALARVP
CEEEEHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCC
ELPEAIPPELLERGDWPSFREALKRIHQPETPVDGLPTGRAWERLAFDELYAHQVTLALV
CCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RQTQVKAGGRPTRGDGRLAAAILKALPFRLTSAQEEALAAIRADLAADTRMLRLLQGDVG
HHHHHHCCCCCCCCCCHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SGKTVVALLAAAAAIEAGRQAALMAPTEILARQHLETIAPLAAAAGIEVAVLTGREKGRT
CCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
RAGILEGLASGRIGLVVGTHALIQDDVAFADLALAIVDEQHRFGVEQRLTFSRKGAAVDM
HHHHHHHHHCCCEEEEECCHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHHCCCCCCEEE
LLMTATPIPRTLVLTLFGDMDSSELREKPPGRKPVDTRSVSLERLDEVVGALGRQLRDGA
HEEECCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
QAYWICPLVEESDTSDLAAATERAAHLKKVFGEKAVELVHGRMSGADKDAAMARFASGEA
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
RILVATTVVEVGVNVPNATLMVIEHAERFGLAQLHQLRGRVGRGEKASTCLLLFRGPLSE
EEEEEEEEHHHCCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCC
TSKARLAILRESEDGFRIAEEDLRLRGEGDVLGTKQSGLPGFKVARMEVHGALVSQARDA
CCCCEEEEEEECCCCCEEEHHHHEECCCCCEECCCCCCCCCCEEEHHHHHHHHHHHHHHH
AARLVPGNPDLEGPEGERVRTLLYVQERDAAVRLLSAG
HHEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]