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The map label for this gene is frr

Identifier: 158423320

GI number: 158423320

Start: 1942961

End: 1943521

Strand: Direct

Name: frr

Synonym: AZC_1696

Alternate gene names: 158423320

Gene position: 1942961-1943521 (Clockwise)

Preceding gene: 158423319

Following gene: 158423321

Centisome position: 36.18

GC content: 65.6

Gene sequence:

>561_bases
ATGACCACCGCCTTCGACATTGCAGACATCAAGCGCCGCATGGCCGGTGCCGTTACGTCCCTGAAGCAGGAACTGGGTGG
TCTGCGCACCGGTCGGGCCTCCGCCAGCCTGCTGGAGCCGATCACGGTGGATGCCTACGGCGCCAACATGCCGCTGGCCC
AGGTGGCCACCGTCTCCGTGCCCGAGCCGCGGCTGCTCTCGGTGCAGGTGTGGGATCGCGGCATGGTCAATGCCGTGGAG
AAGGCGATCCGCGACAGCAACCTCGGCCTCAACCCCAACACCGAGGGCCAGACCCTGCGCATCCGCATCCCGGAGCTCAA
TGAGGAGCGCCGCAAGGAGCTGGTGAAGGTCGCCCACAAATATGCCGAGGCCGCCCGCGTCGCCGTCCGCCATGTGCGCC
GCGACGGCATGGACCTGCTGAAGAAGCTGGAAAAGGACAGCGCCATCAGCTCCGACGACATGGAGCGCCTGTCCAAGGAC
GTGCAGAAGGCGACCGACGAGACCATCTCCGAGGTGGATCAGACCCTCGCCCACAAGGAAAAGGAAATCCTCTCGGTCTG
A

Upstream 100 bases:

>100_bases
TTCCAGCCTCGGTTTTCTGCAGGATCGGCGGCGCGCCGCCACCTCCCGCACCAGTCGCCGGCGCGTCCGTCGCGCCGCGA
GAATACGATAGAGGACAGCC

Downstream 100 bases:

>100_bases
GAGCGGTTTCGGCTTGGCGGGGGAGCGGCCCATGTCCCGGGCAGATGGCGTGCAAGACAGCGTCCCGGAGGCCGGTTCCC
CGTCCTGTCCGGCGGGCGTG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTTAFDIADIKRRMAGAVTSLKQELGGLRTGRASASLLEPITVDAYGANMPLAQVATVSVPEPRLLSVQVWDRGMVNAVE
KAIRDSNLGLNPNTEGQTLRIRIPELNEERRKELVKVAHKYAEAARVAVRHVRRDGMDLLKKLEKDSAISSDDMERLSKD
VQKATDETISEVDQTLAHKEKEILSV

Sequences:

>Translated_186_residues
MTTAFDIADIKRRMAGAVTSLKQELGGLRTGRASASLLEPITVDAYGANMPLAQVATVSVPEPRLLSVQVWDRGMVNAVE
KAIRDSNLGLNPNTEGQTLRIRIPELNEERRKELVKVAHKYAEAARVAVRHVRRDGMDLLKKLEKDSAISSDDMERLSKD
VQKATDETISEVDQTLAHKEKEILSV
>Mature_185_residues
TTAFDIADIKRRMAGAVTSLKQELGGLRTGRASASLLEPITVDAYGANMPLAQVATVSVPEPRLLSVQVWDRGMVNAVEK
AIRDSNLGLNPNTEGQTLRIRIPELNEERRKELVKVAHKYAEAARVAVRHVRRDGMDLLKKLEKDSAISSDDMERLSKDV
QKATDETISEVDQTLAHKEKEILSV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=31.4917127071823, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI291042689, Length=156, Percent_Identity=35.8974358974359, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=49.4505494505495, Blast_Score=165, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=28.4090909090909, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_AZOC5 (A8I468)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001524612.1
- ProteinModelPortal:   A8I468
- SMR:   A8I468
- GeneID:   5688106
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_1696
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   ACAU438753:AZC_1696-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20586; Mature: 20455

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAFDIADIKRRMAGAVTSLKQELGGLRTGRASASLLEPITVDAYGANMPLAQVATVSV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHCCCC
PEPRLLSVQVWDRGMVNAVEKAIRDSNLGLNPNTEGQTLRIRIPELNEERRKELVKVAHK
CCCCEEEEEHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
YAEAARVAVRHVRRDGMDLLKKLEKDSAISSDDMERLSKDVQKATDETISEVDQTLAHKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEILSV
HHHHCC
>Mature Secondary Structure 
TTAFDIADIKRRMAGAVTSLKQELGGLRTGRASASLLEPITVDAYGANMPLAQVATVSV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEECCCCCCCHHHHHCCCC
PEPRLLSVQVWDRGMVNAVEKAIRDSNLGLNPNTEGQTLRIRIPELNEERRKELVKVAHK
CCCCEEEEEHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
YAEAARVAVRHVRRDGMDLLKKLEKDSAISSDDMERLSKDVQKATDETISEVDQTLAHKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEILSV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA