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The map label for this gene is uppS2 [H]

Identifier: 158423321

GI number: 158423321

Start: 1943535

End: 1944329

Strand: Direct

Name: uppS2 [H]

Synonym: AZC_1697

Alternate gene names: 158423321

Gene position: 1943535-1944329 (Clockwise)

Preceding gene: 158423320

Following gene: 158423322

Centisome position: 36.19

GC content: 69.69

Gene sequence:

>795_bases
TTGGCGGGGGAGCGGCCCATGTCCCGGGCAGATGGCGTGCAAGACAGCGTCCCGGAGGCCGGTTCCCCGTCCTGTCCGGC
GGGCGTGCCCGTCCATGTGGGCATCATCATGGATGGCAACGGCCGCTGGGCCACCTCGCGCAAGCTGCCGCGCGTGGAAG
GCCATCGGCGCGGGGTGGAGGCGCTGCGCCGCTGCGTGCGCTCCGCCCGCGAGATCGGCATCCGGTTTCTGACCATCTAC
AGCTTCTCGAGCGAGAACTGGTCGCGCCCGGTGAGCGAGATTTCCGAGCTCATGGGCCTGCTGCGCCGCTTCCTGCGCCA
TGACCTCGCCGAACTGCACGCCGCCAACGTGCGCGTGCGCATCATCGGCGAGCGCGCCTCGCTCTCCCGCGACCTGTCCG
CCATGCTGGACGAGGCCGAGGCGCTGACCGCCGCCAACACCGGCCTCACGCTCGTTGTCGCTTTCAATTACGGCAGCCGG
CAGGAGATTGCGGAAGCCGCAGCCCGCCTTGCGGCGGAGGTCGCCGCCGGCACGCTGCGTCCGGAAGAGATCACGGCCGA
CCTGCTGGGCAGCCGCCTTCTCACGGCAGGCATCCCCGATCCCGACCTCATCATCCGCACCAGCGGCGAGCAGCGGCTTT
CCAACTTCCTGCTGTGGCAGGCTGCGTATGCGGAACTTGTCTTCCTGCCCATCTACTGGCCGGACTTCGACCATGCGGCG
CTGCTCGGGGCGCTTCAGGAATATGCCCGGCGCGACCGCCGGTTCGGCGGACTGACCGCCCGCACCGGCAGTTGA

Upstream 100 bases:

>100_bases
AAGGACGTGCAGAAGGCGACCGACGAGACCATCTCCGAGGTGGATCAGACCCTCGCCCACAAGGAAAAGGAAATCCTCTC
GGTCTGAGAGCGGTTTCGGC

Downstream 100 bases:

>100_bases
TCCCCGTGGTCATTGGACCGGACCTCAAGCAGCGCACGCTGTCAGCCATCGTGCTCGCCCCCGTGGTTCTCGCGACCACC
GTCTTCGGCGGGCTGCCTTT

Product: di-trans-poly-cis-decaprenylcistransferase

Products: NA

Alternate protein names: UPP synthase 2; Di-trans,poly-cis-decaprenylcistransferase 2; Undecaprenyl diphosphate synthase 2; UDS 2 [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MAGERPMSRADGVQDSVPEAGSPSCPAGVPVHVGIIMDGNGRWATSRKLPRVEGHRRGVEALRRCVRSAREIGIRFLTIY
SFSSENWSRPVSEISELMGLLRRFLRHDLAELHAANVRVRIIGERASLSRDLSAMLDEAEALTAANTGLTLVVAFNYGSR
QEIAEAAARLAAEVAAGTLRPEEITADLLGSRLLTAGIPDPDLIIRTSGEQRLSNFLLWQAAYAELVFLPIYWPDFDHAA
LLGALQEYARRDRRFGGLTARTGS

Sequences:

>Translated_264_residues
MAGERPMSRADGVQDSVPEAGSPSCPAGVPVHVGIIMDGNGRWATSRKLPRVEGHRRGVEALRRCVRSAREIGIRFLTIY
SFSSENWSRPVSEISELMGLLRRFLRHDLAELHAANVRVRIIGERASLSRDLSAMLDEAEALTAANTGLTLVVAFNYGSR
QEIAEAAARLAAEVAAGTLRPEEITADLLGSRLLTAGIPDPDLIIRTSGEQRLSNFLLWQAAYAELVFLPIYWPDFDHAA
LLGALQEYARRDRRFGGLTARTGS
>Mature_263_residues
AGERPMSRADGVQDSVPEAGSPSCPAGVPVHVGIIMDGNGRWATSRKLPRVEGHRRGVEALRRCVRSAREIGIRFLTIYS
FSSENWSRPVSEISELMGLLRRFLRHDLAELHAANVRVRIIGERASLSRDLSAMLDEAEALTAANTGLTLVVAFNYGSRQ
EIAEAAARLAAEVAAGTLRPEEITADLLGSRLLTAGIPDPDLIIRTSGEQRLSNFLLWQAAYAELVFLPIYWPDFDHAAL
LGALQEYARRDRRFGGLTARTGS

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=223, Percent_Identity=38.5650224215247, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI45580742, Length=223, Percent_Identity=38.5650224215247, Blast_Score=155, Evalue=3e-38,
Organism=Escherichia coli, GI1786371, Length=236, Percent_Identity=47.8813559322034, Blast_Score=224, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI71993029, Length=225, Percent_Identity=36, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319474, Length=213, Percent_Identity=37.0892018779343, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323748, Length=241, Percent_Identity=29.4605809128631, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18857969, Length=228, Percent_Identity=38.1578947368421, Blast_Score=148, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28904; Mature: 28773

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGERPMSRADGVQDSVPEAGSPSCPAGVPVHVGIIMDGNGRWATSRKLPRVEGHRRGVE
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHHH
ALRRCVRSAREIGIRFLTIYSFSSENWSRPVSEISELMGLLRRFLRHDLAELHAANVRVR
HHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IIGERASLSRDLSAMLDEAEALTAANTGLTLVVAFNYGSRQEIAEAAARLAAEVAAGTLR
EEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
PEEITADLLGSRLLTAGIPDPDLIIRTSGEQRLSNFLLWQAAYAELVFLPIYWPDFDHAA
HHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHH
LLGALQEYARRDRRFGGLTARTGS
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AGERPMSRADGVQDSVPEAGSPSCPAGVPVHVGIIMDGNGRWATSRKLPRVEGHRRGVE
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCHHHHHHH
ALRRCVRSAREIGIRFLTIYSFSSENWSRPVSEISELMGLLRRFLRHDLAELHAANVRVR
HHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
IIGERASLSRDLSAMLDEAEALTAANTGLTLVVAFNYGSRQEIAEAAARLAAEVAAGTLR
EEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
PEEITADLLGSRLLTAGIPDPDLIIRTSGEQRLSNFLLWQAAYAELVFLPIYWPDFDHAA
HHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHH
LLGALQEYARRDRRFGGLTARTGS
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]