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The map label for this gene is ribE [H]

Identifier: 158422888

GI number: 158422888

Start: 1414712

End: 1415323

Strand: Direct

Name: ribE [H]

Synonym: AZC_1264

Alternate gene names: 158422888

Gene position: 1414712-1415323 (Clockwise)

Preceding gene: 158422887

Following gene: 158422889

Centisome position: 26.35

GC content: 65.03

Gene sequence:

>612_bases
ATGTTCACTGGCATCGTCACGGATCTCGGCGAGATCGTCGATCTGGAAGTGCACAATGAAGTGCGCACCTTCGGCATCGC
GACCGACTACAAGCCTTCCTCCATCGATATCGGCGCCTCCATCGCCTGTTCCGGCGTGTGCCTGACGGTGACCAAGGTGA
AGAAGCGCGGGCCCAAGCGCGCCGTCTTCTACGTGGACGCCGCCCCCGAGACGCTGGCCATCACCACGGTGGCGAAGTGG
CGCGAGGGGGCGCGGATCAATCTGGAGCGCTCGCTGACCATTGGCGGCGAGCTCGGCGGACATCTCGTGACCGGCCATGT
GGACGGCATCGCGAGGGTCGTTGCCCGCGACGATTTCGAGGAGACGAGCCGCTTCACCTTCGAGGCGCCGGAGCCGCTGG
CCCGCTTCATCGCCGCCAAGGGCTCGGTGTGTCTCGATGGCACGTCCCTGACCGTCAATACGGTGAAGGGCAACCGGTTC
TCGTGCCTGCTCATCCCCCACACGCTTGCCGTCACCACCTGGGGCGTCGTGCAGGCGGAAGATGAGATCAATCTCGAAGT
GGACCTCATGGCCCGCTATGCCGCGCGCCTTGCGCAGTATGAGCCGGCCTAG

Upstream 100 bases:

>100_bases
GTGGGTGGTGGTACAGAGGCGTTTCGATCCCCGTGCAGCCGCTCCTTGGGCAGGCCGCGCGGCCCCACTCATTGCGGCGA
AGACCCGCGCGGACGGAACC

Downstream 100 bases:

>100_bases
AGGGCGTCAGGCTTCGATTGCCCGGCAATTGAAGCCGTAAGACGCTCTCCATTTGAAATCGGAGCCGGATTTCCCGGGCA
GAAGGATTTCCTCTGACCCC

Product: riboflavin synthase alpha chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFTGIVTDLGEIVDLEVHNEVRTFGIATDYKPSSIDIGASIACSGVCLTVTKVKKRGPKRAVFYVDAAPETLAITTVAKW
REGARINLERSLTIGGELGGHLVTGHVDGIARVVARDDFEETSRFTFEAPEPLARFIAAKGSVCLDGTSLTVNTVKGNRF
SCLLIPHTLAVTTWGVVQAEDEINLEVDLMARYAARLAQYEPA

Sequences:

>Translated_203_residues
MFTGIVTDLGEIVDLEVHNEVRTFGIATDYKPSSIDIGASIACSGVCLTVTKVKKRGPKRAVFYVDAAPETLAITTVAKW
REGARINLERSLTIGGELGGHLVTGHVDGIARVVARDDFEETSRFTFEAPEPLARFIAAKGSVCLDGTSLTVNTVKGNRF
SCLLIPHTLAVTTWGVVQAEDEINLEVDLMARYAARLAQYEPA
>Mature_203_residues
MFTGIVTDLGEIVDLEVHNEVRTFGIATDYKPSSIDIGASIACSGVCLTVTKVKKRGPKRAVFYVDAAPETLAITTVAKW
REGARINLERSLTIGGELGGHLVTGHVDGIARVVARDDFEETSRFTFEAPEPLARFIAAKGSVCLDGTSLTVNTVKGNRF
SCLLIPHTLAVTTWGVVQAEDEINLEVDLMARYAARLAQYEPA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=190, Percent_Identity=34.2105263157895, Blast_Score=99, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319733, Length=204, Percent_Identity=34.3137254901961, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21924; Mature: 21924

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDLGEIVDLEVHNEVRTFGIATDYKPSSIDIGASIACSGVCLTVTKVKKRGPKR
CCCCHHHCCHHEEEEEECCCEEEEEEECCCCCCCCCCCCEEEECCEEEEEEEHHHCCCCE
AVFYVDAAPETLAITTVAKWREGARINLERSLTIGGELGGHLVTGHVDGIARVVARDDFE
EEEEEECCCCEEEEEEEHHHCCCCEEEEEEEEEECCCCCCEEEEECHHHHHHHHHCCCCH
ETSRFTFEAPEPLARFIAAKGSVCLDGTSLTVNTVKGNRFSCLLIPHTLAVTTWGVVQAE
HHCCEEECCCHHHHHHHHCCCCEEECCCEEEEEEECCCEEEEEEECCEEEEEEEEEEEEC
DEINLEVDLMARYAARLAQYEPA
CCCCEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIVTDLGEIVDLEVHNEVRTFGIATDYKPSSIDIGASIACSGVCLTVTKVKKRGPKR
CCCCHHHCCHHEEEEEECCCEEEEEEECCCCCCCCCCCCEEEECCEEEEEEEHHHCCCCE
AVFYVDAAPETLAITTVAKWREGARINLERSLTIGGELGGHLVTGHVDGIARVVARDDFE
EEEEEECCCCEEEEEEEHHHCCCCEEEEEEEEEECCCCCCEEEEECHHHHHHHHHCCCCH
ETSRFTFEAPEPLARFIAAKGSVCLDGTSLTVNTVKGNRFSCLLIPHTLAVTTWGVVQAE
HHCCEEECCCHHHHHHHHCCCCEEECCCEEEEEEECCCEEEEEEECCEEEEEEEEEEEEC
DEINLEVDLMARYAARLAQYEPA
CCCCEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]