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The map label for this gene is ribD [H]

Identifier: 158422887

GI number: 158422887

Start: 1413428

End: 1414582

Strand: Direct

Name: ribD [H]

Synonym: AZC_1263

Alternate gene names: 158422887

Gene position: 1413428-1414582 (Clockwise)

Preceding gene: 158422886

Following gene: 158422888

Centisome position: 26.32

GC content: 74.72

Gene sequence:

>1155_bases
ATGAGCGCTGCTGCGGTGGGCCTTGGCCGGGCCGGCGTCTTCTCGCCCGAGGAAGACGAGGCCCTGATGGCGGAGGCGCT
GGCGGTCGGCCAGCTCGGCCTCGGCCGCACCTGGCCCAACCCTTCCGTGGGCGCCGTCGTGGTGCGCCCGACCTCGGCTG
GTCCCCAGATTCTCGGTCGTGCCGGCACGGCGCCCGCCGGCCGTCCCCATGCGGAGCCGCTGGCGCTGGCGCAGGCGGGC
GACGCGGCCCGCGGGGCGACGCTCTATGTCACGCTGGAGCCCTGCTCGCATTTCGGCCGCACGCCGCCCTGCGCGGATGC
GGTGATCGCCGCCGGCATCACCCGCGTGGTTGCGGCGGTGGAGGATCCCGATCCGCGCGTACGGGGCAGGGGGGTCGCCC
GCATGCGCGCGGCGGGCCTGTGGGTCACCGTGGGTGTCGGCGCCGAGCGGGCGCTGGAGGATCATGCGGGCCACATCAGC
CGCGTCACCCGCGGCCGGCCTCACGTGCTCCTCAAGATGGCCGTCTCGGCTGATGGCAAGGCGGGCCTTGAAGGCCCGCG
CCCCGCCGCCATCACCGGCGAGGAGGCGCGCGCCCGTGTCCATCTCATGCGCGCACACGCGGACGCCATCATGGTCGGCA
TCGGCACCGTTCTGGCGGACGATCCGCAGCTCACCGTGCGCCTGCCCGGCATGGAAGGGCGCTCGCCGGTGCGGATCGTG
CTCGACGGCGACCTGCGCCTGCCGACCACCTGCGGCCTGGTGCGTACGGCGGAGCAGGTGCCTGTGTGGGCCATCGCCGC
CGAGGATGCGCCCGCCGAGCGCGAGAAGGCGCTGGTGGATGCGGGTGTTCAGGTGTTGCGCGCCCCCCGCGCTGCTTCCG
GCCGCCTCGATCTCCCGGCGGTGATGAAGCTTCTCGGCCTCCTCGGCGTCACCCGCCTGATGGTGGAAGGCGGCCCGCAG
GTGGCCGCAGCGCTGCTGGATGAGGGGCTGGTGGACGAGGTTGCGGTGCTGCGTTCCCCCGACGCGCTGGGGGCAGGGGG
CCTCGATGCGCTGGCCGGCCGGCCGCTCGCGCGCCTCACCGAGCCGGTGGGCTTTGCGGTGGTGGAGCGCACGGAGCTTG
GCCGCGACAGTCTCATGCGGCTGCGGCGGCTCTGA

Upstream 100 bases:

>100_bases
TGCTGGACGAATTGCAGCTCGGCGAGCGCAAGGCGGAGGCGCTGGCCAAGCTGAAGCGCGCGGACCGCACAGCGTCCGAA
AGCGAACCGGAGTAGGGGCC

Downstream 100 bases:

>100_bases
TCTGCGCCCTGTTTTTGCTGCCGTTGGCGGTGGGTGGTGGTACAGAGGCGTTTCGATCCCCGTGCAGCCGCTCCTTGGGC
AGGCCGCGCGGCCCCACTCA

Product: riboflavin biosynthesis protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSAAAVGLGRAGVFSPEEDEALMAEALAVGQLGLGRTWPNPSVGAVVVRPTSAGPQILGRAGTAPAGRPHAEPLALAQAG
DAARGATLYVTLEPCSHFGRTPPCADAVIAAGITRVVAAVEDPDPRVRGRGVARMRAAGLWVTVGVGAERALEDHAGHIS
RVTRGRPHVLLKMAVSADGKAGLEGPRPAAITGEEARARVHLMRAHADAIMVGIGTVLADDPQLTVRLPGMEGRSPVRIV
LDGDLRLPTTCGLVRTAEQVPVWAIAAEDAPAEREKALVDAGVQVLRAPRAASGRLDLPAVMKLLGLLGVTRLMVEGGPQ
VAAALLDEGLVDEVAVLRSPDALGAGGLDALAGRPLARLTEPVGFAVVERTELGRDSLMRLRRL

Sequences:

>Translated_384_residues
MSAAAVGLGRAGVFSPEEDEALMAEALAVGQLGLGRTWPNPSVGAVVVRPTSAGPQILGRAGTAPAGRPHAEPLALAQAG
DAARGATLYVTLEPCSHFGRTPPCADAVIAAGITRVVAAVEDPDPRVRGRGVARMRAAGLWVTVGVGAERALEDHAGHIS
RVTRGRPHVLLKMAVSADGKAGLEGPRPAAITGEEARARVHLMRAHADAIMVGIGTVLADDPQLTVRLPGMEGRSPVRIV
LDGDLRLPTTCGLVRTAEQVPVWAIAAEDAPAEREKALVDAGVQVLRAPRAASGRLDLPAVMKLLGLLGVTRLMVEGGPQ
VAAALLDEGLVDEVAVLRSPDALGAGGLDALAGRPLARLTEPVGFAVVERTELGRDSLMRLRRL
>Mature_383_residues
SAAAVGLGRAGVFSPEEDEALMAEALAVGQLGLGRTWPNPSVGAVVVRPTSAGPQILGRAGTAPAGRPHAEPLALAQAGD
AARGATLYVTLEPCSHFGRTPPCADAVIAAGITRVVAAVEDPDPRVRGRGVARMRAAGLWVTVGVGAERALEDHAGHISR
VTRGRPHVLLKMAVSADGKAGLEGPRPAAITGEEARARVHLMRAHADAIMVGIGTVLADDPQLTVRLPGMEGRSPVRIVL
DGDLRLPTTCGLVRTAEQVPVWAIAAEDAPAEREKALVDAGVQVLRAPRAASGRLDLPAVMKLLGLLGVTRLMVEGGPQV
AAALLDEGLVDEVAVLRSPDALGAGGLDALAGRPLARLTEPVGFAVVERTELGRDSLMRLRRL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=377, Percent_Identity=39.7877984084881, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39608; Mature: 39477

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAAVGLGRAGVFSPEEDEALMAEALAVGQLGLGRTWPNPSVGAVVVRPTSAGPQILGR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHCC
AGTAPAGRPHAEPLALAQAGDAARGATLYVTLEPCSHFGRTPPCADAVIAAGITRVVAAV
CCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHC
EDPDPRVRGRGVARMRAAGLWVTVGVGAERALEDHAGHISRVTRGRPHVLLKMAVSADGK
CCCCCCCCCCCHHHEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
AGLEGPRPAAITGEEARARVHLMRAHADAIMVGIGTVLADDPQLTVRLPGMEGRSPVRIV
CCCCCCCCCEECCHHHHHHHHHHHHHHCEEEEEHHHHEECCCEEEEEECCCCCCCCEEEE
LDGDLRLPTTCGLVRTAEQVPVWAIAAEDAPAEREKALVDAGVQVLRAPRAASGRLDLPA
EECCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VMKLLGLLGVTRLMVEGGPQVAAALLDEGLVDEVAVLRSPDALGAGGLDALAGRPLARLT
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHH
EPVGFAVVERTELGRDSLMRLRRL
CCCCEEEEEHHHCCHHHHHHHHCC
>Mature Secondary Structure 
SAAAVGLGRAGVFSPEEDEALMAEALAVGQLGLGRTWPNPSVGAVVVRPTSAGPQILGR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHCC
AGTAPAGRPHAEPLALAQAGDAARGATLYVTLEPCSHFGRTPPCADAVIAAGITRVVAAV
CCCCCCCCCCCCCCHHHCCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHC
EDPDPRVRGRGVARMRAAGLWVTVGVGAERALEDHAGHISRVTRGRPHVLLKMAVSADGK
CCCCCCCCCCCHHHEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
AGLEGPRPAAITGEEARARVHLMRAHADAIMVGIGTVLADDPQLTVRLPGMEGRSPVRIV
CCCCCCCCCEECCHHHHHHHHHHHHHHCEEEEEHHHHEECCCEEEEEECCCCCCCCEEEE
LDGDLRLPTTCGLVRTAEQVPVWAIAAEDAPAEREKALVDAGVQVLRAPRAASGRLDLPA
EECCCCCCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
VMKLLGLLGVTRLMVEGGPQVAAALLDEGLVDEVAVLRSPDALGAGGLDALAGRPLARLT
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHH
EPVGFAVVERTELGRDSLMRLRRL
CCCCEEEEEHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]