Click here to switch to the map view.

The map label for this gene is lysR [H]

Identifier: 158422854

GI number: 158422854

Start: 1379867

End: 1380832

Strand: Reverse

Name: lysR [H]

Synonym: AZC_1230

Alternate gene names: 158422854

Gene position: 1380832-1379867 (Counterclockwise)

Preceding gene: 158422864

Following gene: 158422851

Centisome position: 25.71

GC content: 68.94

Gene sequence:

>966_bases
ATGGCCCTGCAGCCCCGGAGTGTTCCCGTGTCCTGGCTCAATCCCCGGCAGATCGAGGCTTTCCGCGCCATCATGGTGTC
CGGCACGGTGACCGATGCCGCCGCCCTCATGGGCGTGACCCAGCCGGCCGTCAGCCGCATGCTCCGTGACCTTCAGGCGA
CGCTGGGGCTCACGCTGTTCGAGCGGCGCGGCGCCAAGCTGGTGCCCACCAATGAGGGGCTGACCGTCTATGCGGAGGTG
GCGCGCTCCTTCGTCGGGCTGGAGCGCATTGCGCACGTGGCGCGGGAGGTGAAGGAGCGGCGCGCCGGTGTGCTGCGCAT
CGCCGCCATGCCGGCGCTCATGAACGGCTTCCTGCCCCGCTTCGTCGGCCGCTTCCTGAAAGACAAGCCGCGCATGGATC
TCTCGCTCAGCGGCGTCAGCTCCCACCTGGTGCTGGAGCACACGCTGTCGGGAGAATGCGATCTCGGCTTCGTCATGGGG
CCGCTCGCCCATGCGGGCCTGATCGCCCATCCCATGCCTTCCGCTCCCATGGTGGCCGTGCTGCCGCAGCATCATCCGCT
GGCGGCCAAGGACGCCATCCATGTCACGGACTTCGATGGTCAGGACTTCATCGCCATGGAGCCGGGCGGCCTCTCGCGCA
TGCAGCTCGACCGCATCATGGAATTGCACAATGTGCGGCCGGCGGTGCGGGCGGAAACCCGCCTCTCGGGCATCGTCTGC
GGCCTCGTCACCTCAGGCCTCGGGGTGAGCGTGTGCGATCCCTTCACGGCCCATGAATTCACCGCGCGGGGCCTCGTCAT
CCGGCCGTTCACGCCATCGGTCGATTTCGAGTTCGCCGCCGTGCGTTCGGCGCAGAAGCGCTTCCCGGCCGTGGGCAAGG
CGCTGCTGGATGCCTTCGTGCTCCACAGCCGCGCCTTCATCGCCGAGGCGCCTTGGACCCAGCCCGAGCCCGCTGCCGCC
GGCTGA

Upstream 100 bases:

>100_bases
GCGCGCCTTTGCCGTCTTTGTGTGCGCGCTGACAAAATGGTCATACAGCGGGGGCTTGTGCGTCCAATGCATTTGGAATG
ATTTTACATAACGAGATGTT

Downstream 100 bases:

>100_bases
GGCCGCTCAGTGGAAGAGGTGCAGCGGCACGAGATGCTGCTGGATCAGATAGAGCAGGCCGGTCACCGTGGCGACGGAGA
GCACCGTGCCCACGAGCACG

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MALQPRSVPVSWLNPRQIEAFRAIMVSGTVTDAAALMGVTQPAVSRMLRDLQATLGLTLFERRGAKLVPTNEGLTVYAEV
ARSFVGLERIAHVAREVKERRAGVLRIAAMPALMNGFLPRFVGRFLKDKPRMDLSLSGVSSHLVLEHTLSGECDLGFVMG
PLAHAGLIAHPMPSAPMVAVLPQHHPLAAKDAIHVTDFDGQDFIAMEPGGLSRMQLDRIMELHNVRPAVRAETRLSGIVC
GLVTSGLGVSVCDPFTAHEFTARGLVIRPFTPSVDFEFAAVRSAQKRFPAVGKALLDAFVLHSRAFIAEAPWTQPEPAAA
G

Sequences:

>Translated_321_residues
MALQPRSVPVSWLNPRQIEAFRAIMVSGTVTDAAALMGVTQPAVSRMLRDLQATLGLTLFERRGAKLVPTNEGLTVYAEV
ARSFVGLERIAHVAREVKERRAGVLRIAAMPALMNGFLPRFVGRFLKDKPRMDLSLSGVSSHLVLEHTLSGECDLGFVMG
PLAHAGLIAHPMPSAPMVAVLPQHHPLAAKDAIHVTDFDGQDFIAMEPGGLSRMQLDRIMELHNVRPAVRAETRLSGIVC
GLVTSGLGVSVCDPFTAHEFTARGLVIRPFTPSVDFEFAAVRSAQKRFPAVGKALLDAFVLHSRAFIAEAPWTQPEPAAA
G
>Mature_320_residues
ALQPRSVPVSWLNPRQIEAFRAIMVSGTVTDAAALMGVTQPAVSRMLRDLQATLGLTLFERRGAKLVPTNEGLTVYAEVA
RSFVGLERIAHVAREVKERRAGVLRIAAMPALMNGFLPRFVGRFLKDKPRMDLSLSGVSSHLVLEHTLSGECDLGFVMGP
LAHAGLIAHPMPSAPMVAVLPQHHPLAAKDAIHVTDFDGQDFIAMEPGGLSRMQLDRIMELHNVRPAVRAETRLSGIVCG
LVTSGLGVSVCDPFTAHEFTARGLVIRPFTPSVDFEFAAVRSAQKRFPAVGKALLDAFVLHSRAFIAEAPWTQPEPAAAG

Specific function: Positive regulatory protein for the occ operon involved in octopine catabolism and uptake. Also acts as a negative regulator of its expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789204, Length=293, Percent_Identity=36.518771331058, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788481, Length=235, Percent_Identity=28.936170212766, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI157672245, Length=228, Percent_Identity=26.7543859649123, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI145693105, Length=233, Percent_Identity=24.0343347639485, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788887, Length=263, Percent_Identity=25.8555133079848, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790399, Length=203, Percent_Identity=23.6453201970443, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=19.7952218430034, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367136, Length=265, Percent_Identity=21.5094339622642, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790262, Length=292, Percent_Identity=24.3150684931507, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081904, Length=184, Percent_Identity=27.7173913043478, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34660; Mature: 34529

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQPRSVPVSWLNPRQIEAFRAIMVSGTVTDAAALMGVTQPAVSRMLRDLQATLGLTLF
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ERRGAKLVPTNEGLTVYAEVARSFVGLERIAHVAREVKERRAGVLRIAAMPALMNGFLPR
HHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHH
FVGRFLKDKPRMDLSLSGVSSHLVLEHTLSGECDLGFVMGPLAHAGLIAHPMPSAPMVAV
HHHHHHCCCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
LPQHHPLAAKDAIHVTDFDGQDFIAMEPGGLSRMQLDRIMELHNVRPAVRAETRLSGIVC
CCCCCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GLVTSGLGVSVCDPFTAHEFTARGLVIRPFTPSVDFEFAAVRSAQKRFPAVGKALLDAFV
HHHHCCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
LHSRAFIAEAPWTQPEPAAAG
HHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure 
ALQPRSVPVSWLNPRQIEAFRAIMVSGTVTDAAALMGVTQPAVSRMLRDLQATLGLTLF
CCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ERRGAKLVPTNEGLTVYAEVARSFVGLERIAHVAREVKERRAGVLRIAAMPALMNGFLPR
HHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHH
FVGRFLKDKPRMDLSLSGVSSHLVLEHTLSGECDLGFVMGPLAHAGLIAHPMPSAPMVAV
HHHHHHCCCCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
LPQHHPLAAKDAIHVTDFDGQDFIAMEPGGLSRMQLDRIMELHNVRPAVRAETRLSGIVC
CCCCCCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GLVTSGLGVSVCDPFTAHEFTARGLVIRPFTPSVDFEFAAVRSAQKRFPAVGKALLDAFV
HHHHCCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHH
LHSRAFIAEAPWTQPEPAAAG
HHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1799698 [H]