Click here to switch to the map view.

The map label for this gene is dctB [H]

Identifier: 158422790

GI number: 158422790

Start: 1300838

End: 1302955

Strand: Reverse

Name: dctB [H]

Synonym: AZC_1166

Alternate gene names: 158422790

Gene position: 1302955-1300838 (Counterclockwise)

Preceding gene: 158422791

Following gene: 158422789

Centisome position: 24.26

GC content: 64.87

Gene sequence:

>2118_bases
ATGCGGCTGGCCGCCACCCGGAGAGCGATCAGCGAGATATTCGACGGTTCCTATCAACTCGCCATCAATCTGTTCGTGAT
CTTCCTCCTGATCGCGGCACTGGTGGGCGGCACGGCCGCTGTTCTCGTCGAGCTGAACCTGCGCTCCGAGATCGAAGAAG
CCGAGCTGAATGCGCAGAAGACGGCCTATATTCTCCTGCACAATTTCGAGCAGACCGTAGAGCCCATCGACGCACTGCTT
CTCAACATCGCCAATGCCATCGACGGCAGCAACACGCCCACCGAAGTCTATGACTTCCTGCGCGGGCTGAGCATTCCCCC
GTCCATTGTCCAACTGGCGGTGGCCGATACCACCGGCATGATGATCGCCAGCAATCTGTCCCCGCCGGTGGGTGAGCGGG
TGGACCTGTCCGATCGCGAGCACATCCGGGTCCATATGGGCCCCAATCCGCATTCCGGGCTGTTCATCAGCAAGCCTGTG
CTCGGCCGCGTTTCCAAGCGCTGGACCATCCAATTTTCCCGCGCCTGGTATGACCATGCGGGCCAGTTCCGCGGCGTGGT
GATCGCCTCCTACAACATCTTCGACTTCATCAGCTTCTACAGCCGGCTGCGCATCGACCCGAACTCGCTCATCTCGCTGA
TCGGCACCGATGGCGTCGTGCGGGCACGCGCGGCCGCGACGGTCAGCTTCGGCGAGGACGTCCGCAACAGTCCCGCCTTC
ACCCGCATCCTGCGCGCGCAGGAAGTGCCCTATGACCAGGTCAGCGGCGTCGATGGCATCGACCGCGTGGGTTATTACGT
CCGTTCCGACCGCTATCCCATCGTCATGCTGGTGGCCTACGACAAGGCCTATATCCGCGGCCTGAGCTATGATTTCCGCA
TCACCGTATGGATCACCGCGGCCTGCCTCGGTGCGGTACTTTTCGTGCTCGGCGTGGTGGCCATGGCCTACCATCGGCTA
CAGCAGCGGGTGCGCGCCAGCGCCCTGCGCGAAGGCGCCCGGCAGCGCGAGGTGCACTTCCTGGAGGCGATGGCCGGCGT
GCCCGGCGTCTGCGTCGTCCATGTCACGGACCAGGGCAGCCGGCAGGTGGGCGACACGTCGGGCAGCGTCCTGCCGGCGC
TGATCCACGACTATGTGGCGAGCCCCCGCTTCCGCTCCATCGCCCGCTCCCTCACCGGCCCGCAGGTCAGCGTCGAATAT
TTCGCCAAGGAGGGCGAGGAATTCGAGGTGCAGATGATGATCGCGCCGCTGGAAGAGATCGACCAGATGGGAGACGGCGA
CGGCAGCAAGCGCGACCTCGTGGTATTCGCCGTGGACCAGACCTCCAAGCGCATCGAGGAGAACAACCTCTACCAGATGT
CCAAGCTCGCATCGCTCGGCGAGGTGGCGACCGGGCTCGCGCACGAGATCAACCAGCCGCTCGGGGTCATCCGGCTGGCG
GCCACCAATGCGCTCACCGGCCTCCAGAAGGGCATGCCGGTCGAGCATATGGAGGCCAAGCTCAAGCGCATCATCCAGCA
GACGGTGCGCATGAGCCGCATCATCGACCACATGCGCATCTTCGGCCGCAAGAGCGGCATGCGGCTCGAGCCGAGCGACC
CGATGGAGGCCGTGGACGGCGCCCTTCAGGTGGTGGGCGCCCAGTTGCGGCTGGAGAACGTGTCGGTTGCCGTCTCCGGC
GGCAGCGACGGCTTGCGGGTGCTCTGCCGGCAGGACCAGCTCGAACAGGTGGTCATCAACCTCCTCCAGAACGCCCGGGA
CGCCATCCGCGACCGCCGCCGTTCGGTCGGTGTGGAATATCTCGGCGCCATCACCATCGAGGTTTCGCAGGCCCAGGATG
AAAACCGGGCGCCGCAGGTGCTCATCCGGGTGAAGGACAATGCCGGCGGTATTCCCGAGAATGTCATCGACAAGGTGTTC
CAGCCCTTCTTCACCACCAAGCCTCCGGGACAGGGCACCGGCCTCGGCCTTTCGGTGAGCTTCGGCATCATCCGCGACCA
TGGCGGCACCCTGAGCGTCGAGAACGCCTTCGAGGGCGCGGTCTTCACCATCCGCCTCCCGTCTATGCAGGACAGTCAGT
CTCTCCCGGCGCCGCAGGACATGAGCCTGCGGGCCTGA

Upstream 100 bases:

>100_bases
ACATCGAGCGCGCGAAAGCCGCCGGCGTGATCGATTGCCTGACGAAACCGCTGTCCATGGATGCCCTACAGCGCGCCCTC
AAAGCCTTGCCGGTGTAATC

Downstream 100 bases:

>100_bases
CCCTCGGCGGATCGACGCAGCGACCCCACGGGGGCCTGACGGCACGTCCCATCCGGATCAAGATGGCGCCTGAAGCGCCC
ATGCGGCGCGAAGCGGAGAG

Product: sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MRLAATRRAISEIFDGSYQLAINLFVIFLLIAALVGGTAAVLVELNLRSEIEEAELNAQKTAYILLHNFEQTVEPIDALL
LNIANAIDGSNTPTEVYDFLRGLSIPPSIVQLAVADTTGMMIASNLSPPVGERVDLSDREHIRVHMGPNPHSGLFISKPV
LGRVSKRWTIQFSRAWYDHAGQFRGVVIASYNIFDFISFYSRLRIDPNSLISLIGTDGVVRARAAATVSFGEDVRNSPAF
TRILRAQEVPYDQVSGVDGIDRVGYYVRSDRYPIVMLVAYDKAYIRGLSYDFRITVWITAACLGAVLFVLGVVAMAYHRL
QQRVRASALREGARQREVHFLEAMAGVPGVCVVHVTDQGSRQVGDTSGSVLPALIHDYVASPRFRSIARSLTGPQVSVEY
FAKEGEEFEVQMMIAPLEEIDQMGDGDGSKRDLVVFAVDQTSKRIEENNLYQMSKLASLGEVATGLAHEINQPLGVIRLA
ATNALTGLQKGMPVEHMEAKLKRIIQQTVRMSRIIDHMRIFGRKSGMRLEPSDPMEAVDGALQVVGAQLRLENVSVAVSG
GSDGLRVLCRQDQLEQVVINLLQNARDAIRDRRRSVGVEYLGAITIEVSQAQDENRAPQVLIRVKDNAGGIPENVIDKVF
QPFFTTKPPGQGTGLGLSVSFGIIRDHGGTLSVENAFEGAVFTIRLPSMQDSQSLPAPQDMSLRA

Sequences:

>Translated_705_residues
MRLAATRRAISEIFDGSYQLAINLFVIFLLIAALVGGTAAVLVELNLRSEIEEAELNAQKTAYILLHNFEQTVEPIDALL
LNIANAIDGSNTPTEVYDFLRGLSIPPSIVQLAVADTTGMMIASNLSPPVGERVDLSDREHIRVHMGPNPHSGLFISKPV
LGRVSKRWTIQFSRAWYDHAGQFRGVVIASYNIFDFISFYSRLRIDPNSLISLIGTDGVVRARAAATVSFGEDVRNSPAF
TRILRAQEVPYDQVSGVDGIDRVGYYVRSDRYPIVMLVAYDKAYIRGLSYDFRITVWITAACLGAVLFVLGVVAMAYHRL
QQRVRASALREGARQREVHFLEAMAGVPGVCVVHVTDQGSRQVGDTSGSVLPALIHDYVASPRFRSIARSLTGPQVSVEY
FAKEGEEFEVQMMIAPLEEIDQMGDGDGSKRDLVVFAVDQTSKRIEENNLYQMSKLASLGEVATGLAHEINQPLGVIRLA
ATNALTGLQKGMPVEHMEAKLKRIIQQTVRMSRIIDHMRIFGRKSGMRLEPSDPMEAVDGALQVVGAQLRLENVSVAVSG
GSDGLRVLCRQDQLEQVVINLLQNARDAIRDRRRSVGVEYLGAITIEVSQAQDENRAPQVLIRVKDNAGGIPENVIDKVF
QPFFTTKPPGQGTGLGLSVSFGIIRDHGGTLSVENAFEGAVFTIRLPSMQDSQSLPAPQDMSLRA
>Mature_705_residues
MRLAATRRAISEIFDGSYQLAINLFVIFLLIAALVGGTAAVLVELNLRSEIEEAELNAQKTAYILLHNFEQTVEPIDALL
LNIANAIDGSNTPTEVYDFLRGLSIPPSIVQLAVADTTGMMIASNLSPPVGERVDLSDREHIRVHMGPNPHSGLFISKPV
LGRVSKRWTIQFSRAWYDHAGQFRGVVIASYNIFDFISFYSRLRIDPNSLISLIGTDGVVRARAAATVSFGEDVRNSPAF
TRILRAQEVPYDQVSGVDGIDRVGYYVRSDRYPIVMLVAYDKAYIRGLSYDFRITVWITAACLGAVLFVLGVVAMAYHRL
QQRVRASALREGARQREVHFLEAMAGVPGVCVVHVTDQGSRQVGDTSGSVLPALIHDYVASPRFRSIARSLTGPQVSVEY
FAKEGEEFEVQMMIAPLEEIDQMGDGDGSKRDLVVFAVDQTSKRIEENNLYQMSKLASLGEVATGLAHEINQPLGVIRLA
ATNALTGLQKGMPVEHMEAKLKRIIQQTVRMSRIIDHMRIFGRKSGMRLEPSDPMEAVDGALQVVGAQLRLENVSVAVSG
GSDGLRVLCRQDQLEQVVINLLQNARDAIRDRRRSVGVEYLGAITIEVSQAQDENRAPQVLIRVKDNAGGIPENVIDKVF
QPFFTTKPPGQGTGLGLSVSFGIIRDHGGTLSVENAFEGAVFTIRLPSMQDSQSLPAPQDMSLRA

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=31.6602316602317, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=26.953125, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77370; Mature: 77370

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAATRRAISEIFDGSYQLAINLFVIFLLIAALVGGTAAVLVELNLRSEIEEAELNAQK
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCC
TAYILLHNFEQTVEPIDALLLNIANAIDGSNTPTEVYDFLRGLSIPPSIVQLAVADTTGM
EEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHEEEEECCCCE
MIASNLSPPVGERVDLSDREHIRVHMGPNPHSGLFISKPVLGRVSKRWTIQFSRAWYDHA
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCHHHCCCCEEEEEEHHHHHHCC
GQFRGVVIASYNIFDFISFYSRLRIDPNSLISLIGTDGVVRARAAATVSFGEDVRNSPAF
CCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHEEEECCHHHCCCHHH
TRILRAQEVPYDQVSGVDGIDRVGYYVRSDRYPIVMLVAYDKAYIRGLSYDFRITVWITA
HHHHHHHCCCHHHHCCCCCHHHHCCEEECCCCCEEEEEEECHHHHHCCCCCEEEEHHHHH
ACLGAVLFVLGVVAMAYHRLQQRVRASALREGARQREVHFLEAMAGVPGVCVVHVTDQGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
RQVGDTSGSVLPALIHDYVASPRFRSIARSLTGPQVSVEYFAKEGEEFEVQMMIAPLEEI
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHCCCCCEEEEEEECCHHHH
DQMGDGDGSKRDLVVFAVDQTSKRIEENNLYQMSKLASLGEVATGLAHEINQPLGVIRLA
HHCCCCCCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEH
ATNALTGLQKGMPVEHMEAKLKRIIQQTVRMSRIIDHMRIFGRKSGMRLEPSDPMEAVDG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ALQVVGAQLRLENVSVAVSGGSDGLRVLCRQDQLEQVVINLLQNARDAIRDRRRSVGVEY
HHHHHHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LGAITIEVSQAQDENRAPQVLIRVKDNAGGIPENVIDKVFQPFFTTKPPGQGTGLGLSVS
EEEEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEE
FGIIRDHGGTLSVENAFEGAVFTIRLPSMQDSQSLPAPQDMSLRA
EEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLAATRRAISEIFDGSYQLAINLFVIFLLIAALVGGTAAVLVELNLRSEIEEAELNAQK
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCC
TAYILLHNFEQTVEPIDALLLNIANAIDGSNTPTEVYDFLRGLSIPPSIVQLAVADTTGM
EEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHEEEEECCCCE
MIASNLSPPVGERVDLSDREHIRVHMGPNPHSGLFISKPVLGRVSKRWTIQFSRAWYDHA
EEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCHHHCCCCEEEEEEHHHHHHCC
GQFRGVVIASYNIFDFISFYSRLRIDPNSLISLIGTDGVVRARAAATVSFGEDVRNSPAF
CCCCEEEEEECHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHEEEECCHHHCCCHHH
TRILRAQEVPYDQVSGVDGIDRVGYYVRSDRYPIVMLVAYDKAYIRGLSYDFRITVWITA
HHHHHHHCCCHHHHCCCCCHHHHCCEEECCCCCEEEEEEECHHHHHCCCCCEEEEHHHHH
ACLGAVLFVLGVVAMAYHRLQQRVRASALREGARQREVHFLEAMAGVPGVCVVHVTDQGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
RQVGDTSGSVLPALIHDYVASPRFRSIARSLTGPQVSVEYFAKEGEEFEVQMMIAPLEEI
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEHHHHHCCCCCEEEEEEECCHHHH
DQMGDGDGSKRDLVVFAVDQTSKRIEENNLYQMSKLASLGEVATGLAHEINQPLGVIRLA
HHCCCCCCCCCEEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEH
ATNALTGLQKGMPVEHMEAKLKRIIQQTVRMSRIIDHMRIFGRKSGMRLEPSDPMEAVDG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
ALQVVGAQLRLENVSVAVSGGSDGLRVLCRQDQLEQVVINLLQNARDAIRDRRRSVGVEY
HHHHHHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LGAITIEVSQAQDENRAPQVLIRVKDNAGGIPENVIDKVFQPFFTTKPPGQGTGLGLSVS
EEEEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEE
FGIIRDHGGTLSVENAFEGAVFTIRLPSMQDSQSLPAPQDMSLRA
EEEEECCCCEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]