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The map label for this gene is ptrB [H]

Identifier: 158422708

GI number: 158422708

Start: 1213552

End: 1215537

Strand: Reverse

Name: ptrB [H]

Synonym: AZC_1084

Alternate gene names: 158422708

Gene position: 1215537-1213552 (Counterclockwise)

Preceding gene: 158422709

Following gene: 158422706

Centisome position: 22.64

GC content: 67.17

Gene sequence:

>1986_bases
ATGCGTGATCCTGCGCTCCTGCCCGCCGACATCCGCACCTATCTGGAAGCCGAGAACAGCTATTCTGCGCACTACTTTGC
CGCCTATGGAGAGCTGAAGGAGCGGCTGATCACGGAAATGCGCGGACGCATCAAGGAAGATGATGCGAACGTTCCATCGC
CGGACGGCGCCTTCGCATATTATTCCCGCCACCGCACCGGCGGGCAGCATCCGCTCATCTGCCGCAAGGCCCTGCCCGAC
GGCGCAGAGGAGATCCTGCTGGACGGCGACAGGGAAGCGGAAGGCAAGGCCTATTTCCGCCTCGCGCCCGCCCGCCACAG
CCGCGACCACGCCCGGCTCGCCTATGCCGCGGACGAGGCGGGCTCGGAACTGTTCACCTTGCGGGTGCGGGACCTTGCGA
CCGGCGCCAACCTGCCCTTCAGCATAGCGGATACCACCGGCGACCTGCTCTGGGGCGGCGACGCCGAGACCCTCTATTAC
ATCCGCCGCGACGAGGAACACCGTCCTTCCATGGTGTTCCGTCACCGCATCGGCACGCCGCCGGAGAGCGACGAACTCAT
CTATCAGGAGCCGGACAAGGGGTTCTTTGTTTCACTGGGTGAAACCCAGTCGGGGACTTTCGGCCTCATCGCCTGCGGCG
ACCATGAGACGTCGGAAGTCCATCTGCTCGACCTCGCCGACCCGTCCGCCACACCCCGCCTCGTCGCCGCGCGCACCGTC
GGGCTGCGCTATGACGTGGAGCACCACCCCGATCTGGGCGGCGCCGATACCCTCATCCTGCTCACCAATGCGGACGGGGC
CGAAGACTTCAAGCTCGTGACAGCTCCGACCGCCGCGCCGCAGAAGGCGAACTGGCGCGATCTCGTGCCGCACCGTGCCG
GGCGCATGATCCTGTCCCACACCGCCTACCGGCATTTCCTGGTCCGGCTCGAGCGGGAGGACGGCCTCCCGCGCGTCACG
CTGCGGGCGCTGGCAAGCGGCGAGGAGCATGCCATCGCCTTCGCCGAGGAGGCTTATGGGCTCGGCCTCAACGGCGGCTA
TGAGTTCGATCCGAAAAGCCTGCGCTTCACCTATTCCTCCATGACCACCCCGGCTGAGGAATGGGATTACGACATGGCCG
CACGCACCCGCGCGCTGCTGAAGCGGCAGGAGGTGCCGAGCGGGCATGACCCGGCGGCTTATGTGACCCGCCGCCTGTTC
GCGACGGCCGCGGATGGTGAGCAGGTGCCCATCTCCCTGCTCTACCGCGCCGATACGCCGCTCGACGGCAGCGCACCCTG
CCTGCTCTATGGCTATGGCGCCTACGGCATGTCCATGCCGGCGAGCTTCTCCACCACCCGCCTGTCGCTGGTGGATCGGG
GATTCGTCTATGCCATCGCCCACGTGCGCGGCGGCACGGAAAAGGGCTGGCACTGGTACACGGACGGCAAGCTGGCGAAG
AAGACCAACACCTTCACGGACTTCATCGCCGCAGCCGAACATCTGGTGCAGGCGCGCCTCACCCGGCCGGAGAAGATCGT
CGCGCAGGGCGGCTCGGCGGGCGGCATGCTCATGGGCGCCATCGCCAACATGCGGCCGGACCTGTTCGCGGGCATCGTCG
CCGAGGTGCCGTTCGTGGACGTGCTCGCCACCATGCTGGACGACACGCTGCCCCTCACCCCGCCCGAATGGCCCGAATGG
GGCAATCCGATCATCGATCCGGACGCCTTCCGCACCATCCTCGGCTATTCGCCCGTGGACAATGTGACGGCGCAGGCCTA
CCCGGCGCTCTTCGCACTCGCCGGCCTCACCGACCCGCGCGTCACCTATTGGGAACCGGCCAAATGGATCGCGCGGCTGC
GGGCGGCCAATACCGGTACGGCACCGATCCTGCTCAAGACCAATATGGAGGCGGGCCATGGCGGCGCCGCCGGCCGGTTC
GACCGGCTGGAGGAAGTGGCGCTCGTATACATCTTCGCGCTGAAGACGGCCGGCGTCATCGCCTGA

Upstream 100 bases:

>100_bases
TCTTCCCGAGGCTCCCCGCCGTCCGACCGCCCGCACGCTGCACGGCGTCACGGTCCATGATGATTACGCCTGGTTGCGGG
CCGACAACTGGCGCGACGTC

Downstream 100 bases:

>100_bases
CCGTCGCAAGAACGGGCGGCGCCGGTCCTTCGAGGACCGGCCCGCTCAGGCCGGCAGGGCCGACAGCGTGACGGTCTCTC
CGTCCTGGGAGAAGCCGAGC

Product: peptidase

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MRDPALLPADIRTYLEAENSYSAHYFAAYGELKERLITEMRGRIKEDDANVPSPDGAFAYYSRHRTGGQHPLICRKALPD
GAEEILLDGDREAEGKAYFRLAPARHSRDHARLAYAADEAGSELFTLRVRDLATGANLPFSIADTTGDLLWGGDAETLYY
IRRDEEHRPSMVFRHRIGTPPESDELIYQEPDKGFFVSLGETQSGTFGLIACGDHETSEVHLLDLADPSATPRLVAARTV
GLRYDVEHHPDLGGADTLILLTNADGAEDFKLVTAPTAAPQKANWRDLVPHRAGRMILSHTAYRHFLVRLEREDGLPRVT
LRALASGEEHAIAFAEEAYGLGLNGGYEFDPKSLRFTYSSMTTPAEEWDYDMAARTRALLKRQEVPSGHDPAAYVTRRLF
ATAADGEQVPISLLYRADTPLDGSAPCLLYGYGAYGMSMPASFSTTRLSLVDRGFVYAIAHVRGGTEKGWHWYTDGKLAK
KTNTFTDFIAAAEHLVQARLTRPEKIVAQGGSAGGMLMGAIANMRPDLFAGIVAEVPFVDVLATMLDDTLPLTPPEWPEW
GNPIIDPDAFRTILGYSPVDNVTAQAYPALFALAGLTDPRVTYWEPAKWIARLRAANTGTAPILLKTNMEAGHGGAAGRF
DRLEEVALVYIFALKTAGVIA

Sequences:

>Translated_661_residues
MRDPALLPADIRTYLEAENSYSAHYFAAYGELKERLITEMRGRIKEDDANVPSPDGAFAYYSRHRTGGQHPLICRKALPD
GAEEILLDGDREAEGKAYFRLAPARHSRDHARLAYAADEAGSELFTLRVRDLATGANLPFSIADTTGDLLWGGDAETLYY
IRRDEEHRPSMVFRHRIGTPPESDELIYQEPDKGFFVSLGETQSGTFGLIACGDHETSEVHLLDLADPSATPRLVAARTV
GLRYDVEHHPDLGGADTLILLTNADGAEDFKLVTAPTAAPQKANWRDLVPHRAGRMILSHTAYRHFLVRLEREDGLPRVT
LRALASGEEHAIAFAEEAYGLGLNGGYEFDPKSLRFTYSSMTTPAEEWDYDMAARTRALLKRQEVPSGHDPAAYVTRRLF
ATAADGEQVPISLLYRADTPLDGSAPCLLYGYGAYGMSMPASFSTTRLSLVDRGFVYAIAHVRGGTEKGWHWYTDGKLAK
KTNTFTDFIAAAEHLVQARLTRPEKIVAQGGSAGGMLMGAIANMRPDLFAGIVAEVPFVDVLATMLDDTLPLTPPEWPEW
GNPIIDPDAFRTILGYSPVDNVTAQAYPALFALAGLTDPRVTYWEPAKWIARLRAANTGTAPILLKTNMEAGHGGAAGRF
DRLEEVALVYIFALKTAGVIA
>Mature_661_residues
MRDPALLPADIRTYLEAENSYSAHYFAAYGELKERLITEMRGRIKEDDANVPSPDGAFAYYSRHRTGGQHPLICRKALPD
GAEEILLDGDREAEGKAYFRLAPARHSRDHARLAYAADEAGSELFTLRVRDLATGANLPFSIADTTGDLLWGGDAETLYY
IRRDEEHRPSMVFRHRIGTPPESDELIYQEPDKGFFVSLGETQSGTFGLIACGDHETSEVHLLDLADPSATPRLVAARTV
GLRYDVEHHPDLGGADTLILLTNADGAEDFKLVTAPTAAPQKANWRDLVPHRAGRMILSHTAYRHFLVRLEREDGLPRVT
LRALASGEEHAIAFAEEAYGLGLNGGYEFDPKSLRFTYSSMTTPAEEWDYDMAARTRALLKRQEVPSGHDPAAYVTRRLF
ATAADGEQVPISLLYRADTPLDGSAPCLLYGYGAYGMSMPASFSTTRLSLVDRGFVYAIAHVRGGTEKGWHWYTDGKLAK
KTNTFTDFIAAAEHLVQARLTRPEKIVAQGGSAGGMLMGAIANMRPDLFAGIVAEVPFVDVLATMLDDTLPLTPPEWPEW
GNPIIDPDAFRTILGYSPVDNVTAQAYPALFALAGLTDPRVTYWEPAKWIARLRAANTGTAPILLKTNMEAGHGGAAGRF
DRLEEVALVYIFALKTAGVIA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172438, Length=465, Percent_Identity=31.8279569892473, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI284172431, Length=465, Percent_Identity=31.8279569892473, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI284172420, Length=465, Percent_Identity=31.8279569892473, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI284172413, Length=465, Percent_Identity=31.8279569892473, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI70778815, Length=465, Percent_Identity=31.8279569892473, Blast_Score=199, Evalue=9e-51,
Organism=Homo sapiens, GI41349456, Length=581, Percent_Identity=24.7848537005164, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI108860686, Length=269, Percent_Identity=36.4312267657993, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI108860692, Length=215, Percent_Identity=38.1395348837209, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1788150, Length=661, Percent_Identity=38.5779122541604, Blast_Score=432, Evalue=1e-122,
Organism=Drosophila melanogaster, GI24583414, Length=677, Percent_Identity=24.0768094534712, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI221510989, Length=686, Percent_Identity=23.3236151603499, Blast_Score=171, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 72528; Mature: 72528

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPALLPADIRTYLEAENSYSAHYFAAYGELKERLITEMRGRIKEDDANVPSPDGAFAY
CCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
YSRHRTGGQHPLICRKALPDGAEEILLDGDREAEGKAYFRLAPARHSRDHARLAYAADEA
EHHCCCCCCCCEEEHHCCCCCCHHHEECCCCCCCCCEEEEECCCCCCCCCCEEEEECCCC
GSELFTLRVRDLATGANLPFSIADTTGDLLWGGDAETLYYIRRDEEHRPSMVFRHRIGTP
CCEEEEEEEEHHCCCCCCCEEEECCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHCCCC
PESDELIYQEPDKGFFVSLGETQSGTFGLIACGDHETSEVHLLDLADPSATPRLVAARTV
CCCCCEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEEEE
GLRYDVEHHPDLGGADTLILLTNADGAEDFKLVTAPTAAPQKANWRDLVPHRAGRMILSH
CEEEECCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHCCHHHCHHHHHH
TAYRHFLVRLEREDGLPRVTLRALASGEEHAIAFAEEAYGLGLNGGYEFDPKSLRFTYSS
HHHHHHHEEEECCCCCCHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCCCCCEEEEECC
MTTPAEEWDYDMAARTRALLKRQEVPSGHDPAAYVTRRLFATAADGEQVPISLLYRADTP
CCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCC
LDGSAPCLLYGYGAYGMSMPASFSTTRLSLVDRGFVYAIAHVRGGTEKGWHWYTDGKLAK
CCCCCCEEEEEECCCCCCCCCCCCCEEEEHHHCCEEEEEEECCCCCCCCCEEEECCEEEC
KTNTFTDFIAAAEHLVQARLTRPEKIVAQGGSAGGMLMGAIANMRPDLFAGIVAEVPFVD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHCCHHH
VLATMLDDTLPLTPPEWPEWGNPIIDPDAFRTILGYSPVDNVTAQAYPALFALAGLTDPR
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
VTYWEPAKWIARLRAANTGTAPILLKTNMEAGHGGAAGRFDRLEEVALVYIFALKTAGVI
CEEECHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
A
C
>Mature Secondary Structure
MRDPALLPADIRTYLEAENSYSAHYFAAYGELKERLITEMRGRIKEDDANVPSPDGAFAY
CCCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
YSRHRTGGQHPLICRKALPDGAEEILLDGDREAEGKAYFRLAPARHSRDHARLAYAADEA
EHHCCCCCCCCEEEHHCCCCCCHHHEECCCCCCCCCEEEEECCCCCCCCCCEEEEECCCC
GSELFTLRVRDLATGANLPFSIADTTGDLLWGGDAETLYYIRRDEEHRPSMVFRHRIGTP
CCEEEEEEEEHHCCCCCCCEEEECCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHCCCC
PESDELIYQEPDKGFFVSLGETQSGTFGLIACGDHETSEVHLLDLADPSATPRLVAARTV
CCCCCEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEEEE
GLRYDVEHHPDLGGADTLILLTNADGAEDFKLVTAPTAAPQKANWRDLVPHRAGRMILSH
CEEEECCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHCCHHHCHHHHHH
TAYRHFLVRLEREDGLPRVTLRALASGEEHAIAFAEEAYGLGLNGGYEFDPKSLRFTYSS
HHHHHHHEEEECCCCCCHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCCCCCEEEEECC
MTTPAEEWDYDMAARTRALLKRQEVPSGHDPAAYVTRRLFATAADGEQVPISLLYRADTP
CCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCC
LDGSAPCLLYGYGAYGMSMPASFSTTRLSLVDRGFVYAIAHVRGGTEKGWHWYTDGKLAK
CCCCCCEEEEEECCCCCCCCCCCCCEEEEHHHCCEEEEEEECCCCCCCCCEEEECCEEEC
KTNTFTDFIAAAEHLVQARLTRPEKIVAQGGSAGGMLMGAIANMRPDLFAGIVAEVPFVD
CCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHCCHHH
VLATMLDDTLPLTPPEWPEWGNPIIDPDAFRTILGYSPVDNVTAQAYPALFALAGLTDPR
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
VTYWEPAKWIARLRAANTGTAPILLKTNMEAGHGGAAGRFDRLEEVALVYIFALKTAGVI
CEEECHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7629037 [H]