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The map label for this gene is cysQ [H]

Identifier: 158422706

GI number: 158422706

Start: 1211786

End: 1212595

Strand: Reverse

Name: cysQ [H]

Synonym: AZC_1082

Alternate gene names: 158422706

Gene position: 1212595-1211786 (Counterclockwise)

Preceding gene: 158422708

Following gene: 158422705

Centisome position: 22.58

GC content: 71.23

Gene sequence:

>810_bases
TTGCCGCCCATGACCGCCCCAGCCGACCTCACCTTCCTCGCCGCTTTGGCCCGCATCGCCCTCGACGCTGGCGCCGTCAT
CCGCCGGATCGAGGCGAACGGCATCCATGCGCGGGAGAAGGCGGACGCCAGCGTGGTGACGGATGCGGACGAGGCCGCAG
AGGCACTCATCTGCCCGGCCCTGCGCACGCTCGCGCCCGGCACGCCCATCATCGCCGAGGAAGCGGTCGCCGCCGGCGGC
GGGGTCGCGCCGGGCCGACGCTTCTTCCTCGTGGATCCGCTGGACGGAACGCGGGAGTTCGTCTCGGGCAATGGCGAGTA
CACGGTGAACATTGCCTTGGTCGAGGATGGCACGCCGCGCTACGGCATCATCTACGCACCGGCCAAGGGCCTGCTCTATG
CGGGCGGCGACGGCGCCGCCTTCAAGGCGCTGCGCGCGCCGGAGGATGCGGTGGTGCCGGAAAGCTGGACGCCCATCCAT
TGCCGGCTGCGCCCCGCCGGGCCCATCCGCGTCTGCGCCAGCCGCTCCCATTCGGACCCCAGCACCAGCGCCTTCATCGG
CGGCTTCGAGGTCGAGGATTGCGTCAACGCCGGCTCGGCCTTGAAATTCGGCCTGCTGGCGGAAGGCGCGGTGGACCTCT
ATCCGCGCCTGTCGCCGGTGATGGAATGGGATTCGGCGGCCGGCCACGCCATCGTGGTGGCCGCCGGCGGCAGCGTGCGC
CGGCCCGATGGATCGCCCCTCACCTACGGCCATCCGGAAAACGACTTCCGCGTCAACGGCTTCATCGCGGAAGGCCGGCC
CGTCGCCTGA

Upstream 100 bases:

>100_bases
CGGCGGCCCGGACGCAGCGACAGGGCGCCCTCTTCCCAAGCGGTCCCGCCCGGCCTAACAAGCGCCCTTTGACAGCGGGC
TCCGCCCCGCCCCGGAGCGA

Downstream 100 bases:

>100_bases
CGGCGGGCGCGGGCTGGCAGCGCGGGTTTGCGCCTCGCCTTGTCTGCGTCACAGTAGCGGGAAACGATCGCCTGCCGAAT
CGTAACGTCCCGCCCGTCGC

Product: 5-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MPPMTAPADLTFLAALARIALDAGAVIRRIEANGIHAREKADASVVTDADEAAEALICPALRTLAPGTPIIAEEAVAAGG
GVAPGRRFFLVDPLDGTREFVSGNGEYTVNIALVEDGTPRYGIIYAPAKGLLYAGGDGAAFKALRAPEDAVVPESWTPIH
CRLRPAGPIRVCASRSHSDPSTSAFIGGFEVEDCVNAGSALKFGLLAEGAVDLYPRLSPVMEWDSAAGHAIVVAAGGSVR
RPDGSPLTYGHPENDFRVNGFIAEGRPVA

Sequences:

>Translated_269_residues
MPPMTAPADLTFLAALARIALDAGAVIRRIEANGIHAREKADASVVTDADEAAEALICPALRTLAPGTPIIAEEAVAAGG
GVAPGRRFFLVDPLDGTREFVSGNGEYTVNIALVEDGTPRYGIIYAPAKGLLYAGGDGAAFKALRAPEDAVVPESWTPIH
CRLRPAGPIRVCASRSHSDPSTSAFIGGFEVEDCVNAGSALKFGLLAEGAVDLYPRLSPVMEWDSAAGHAIVVAAGGSVR
RPDGSPLTYGHPENDFRVNGFIAEGRPVA
>Mature_268_residues
PPMTAPADLTFLAALARIALDAGAVIRRIEANGIHAREKADASVVTDADEAAEALICPALRTLAPGTPIIAEEAVAAGGG
VAPGRRFFLVDPLDGTREFVSGNGEYTVNIALVEDGTPRYGIIYAPAKGLLYAGGDGAAFKALRAPEDAVVPESWTPIHC
RLRPAGPIRVCASRSHSDPSTSAFIGGFEVEDCVNAGSALKFGLLAEGAVDLYPRLSPVMEWDSAAGHAIVVAAGGSVRR
PDGSPLTYGHPENDFRVNGFIAEGRPVA

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=256, Percent_Identity=31.25, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1790659, Length=252, Percent_Identity=38.8888888888889, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI193202572, Length=218, Percent_Identity=29.3577981651376, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324508, Length=307, Percent_Identity=25.4071661237785, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27882; Mature: 27751

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPMTAPADLTFLAALARIALDAGAVIRRIEANGIHAREKADASVVTDADEAAEALICPA
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHH
LRTLAPGTPIIAEEAVAAGGGVAPGRRFFLVDPLDGTREFVSGNGEYTVNIALVEDGTPR
HHHHCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCCEEEEEEEEECCCCC
YGIIYAPAKGLLYAGGDGAAFKALRAPEDAVVPESWTPIHCRLRPAGPIRVCASRSHSDP
EEEEEECCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCC
STSAFIGGFEVEDCVNAGSALKFGLLAEGAVDLYPRLSPVMEWDSAAGHAIVVAAGGSVR
CCEEEECCEEHHHHHCCCCCEEEEEEECCCHHHCCCCCHHHHCCCCCCCEEEEECCCCEE
RPDGSPLTYGHPENDFRVNGFIAEGRPVA
CCCCCCCCCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
PPMTAPADLTFLAALARIALDAGAVIRRIEANGIHAREKADASVVTDADEAAEALICPA
CCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHH
LRTLAPGTPIIAEEAVAAGGGVAPGRRFFLVDPLDGTREFVSGNGEYTVNIALVEDGTPR
HHHHCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCCEEEEEEEEECCCCC
YGIIYAPAKGLLYAGGDGAAFKALRAPEDAVVPESWTPIHCRLRPAGPIRVCASRSHSDP
EEEEEECCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCC
STSAFIGGFEVEDCVNAGSALKFGLLAEGAVDLYPRLSPVMEWDSAAGHAIVVAAGGSVR
CCEEEECCEEHHHHHCCCCCEEEEEEECCCHHHCCCCCHHHHCCCCCCCEEEEECCCCEE
RPDGSPLTYGHPENDFRVNGFIAEGRPVA
CCCCCCCCCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]