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The map label for this gene is hypB [H]

Identifier: 158422232

GI number: 158422232

Start: 673820

End: 674770

Strand: Direct

Name: hypB [H]

Synonym: AZC_0608

Alternate gene names: 158422232

Gene position: 673820-674770 (Clockwise)

Preceding gene: 158422231

Following gene: 158422233

Centisome position: 12.55

GC content: 67.4

Gene sequence:

>951_bases
ATGTGCGTGACCTGCGGCTGCGGCCCTGATGCCGTGACCATCTCCGGCCCGAATGGCGAAGCGCATCACGATCCTGCGCA
CGGCCATGACCATTCTCACGGTCACGACCATGGCCATTCCCACGCCCATGGCGATCACGGCCATGGCCATCATCATCACG
ACGACCACCATCACGGCCACGATGAGCCGCAGCCGGTGCGCTCCCACGCGCCGGGGTTGGAGGCCCGCCGGCTGGTGGAG
ATCGAGCAGAACATCCTCGCCAAGAACGACGGCTTCGCCGATACCAACCGCGCCCGCCTCTCGACCCTCGGCGTCTTCGC
GCTGAACCTGCTCGCCGGCCCCGGCGCCGGCAAGACGACGCTGCTCGTCGAGACGCTGAAGGCGCTGAAGGACAAGATCC
CCGCTGCCGTGATCGAGGGAGACCAGCAGACCAGCAATGATGCCGAGCGCATCCGCGCCGTCGGCGCGCCGGCGGTGCAG
ATCAACACCGGCAAGGGCTGCCATCTCGACGCGCATATGGTCGGCCATGCGCTGGAGCGCCTGCCGCTGGAAGCGGGAGG
CGTGCTGTTCATCGAGAATGTGGGCAACCTCGTCTGCCCCGCCGCCTTTGATCTCGGCGAAGACAAGCGGGTGACGCTGC
TGTCGGTCACAGAGGGCGAGGACAAGCCGCTCAAATATCCCGACATCTTTGAAGGCGCACACCTCGTGCTTCTCACCAAG
GCCGATCTGGTGCCGCATCTCGAGGTGGACGTGGATCTCATCATCGCCAACGTCCGCCGCATCAATCCGCACGCCAAGGT
GCTCACGCTCTCCAGCCGTTCCGGCGATGGCATGCGCGCCTGGCTCTCCTGGTTGGAGGATGTGCGCGCCGAAAAGCTGG
AAGCGCTGGCCGAGGCCGCCGCCGCTCGCGCGGCGGCCCTGCGCGGTGCGGCCCGGCGGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
CGCTCGCCACCCGCCTCGACCCCTGCCCCTGCTGCGGCGGCGAGCGCCTCGTGCCCAATGGCGGCACGGGCATGACCATC
AAGGATCTGGAGGTGGTGTG

Downstream 100 bases:

>100_bases
GCCCATGACCGCGCTCGCCTCGCGTCCCGCCCTTCTCGTGGTCGATGACGAGCCGCGTTCCGTGGAGGTGATGGCGCGCG
TGCTCGGCGAGGAGTTCGAC

Product: hydrogenase accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MCVTCGCGPDAVTISGPNGEAHHDPAHGHDHSHGHDHGHSHAHGDHGHGHHHHDDHHHGHDEPQPVRSHAPGLEARRLVE
IEQNILAKNDGFADTNRARLSTLGVFALNLLAGPGAGKTTLLVETLKALKDKIPAAVIEGDQQTSNDAERIRAVGAPAVQ
INTGKGCHLDAHMVGHALERLPLEAGGVLFIENVGNLVCPAAFDLGEDKRVTLLSVTEGEDKPLKYPDIFEGAHLVLLTK
ADLVPHLEVDVDLIIANVRRINPHAKVLTLSSRSGDGMRAWLSWLEDVRAEKLEALAEAAAARAAALRGAARRAAE

Sequences:

>Translated_316_residues
MCVTCGCGPDAVTISGPNGEAHHDPAHGHDHSHGHDHGHSHAHGDHGHGHHHHDDHHHGHDEPQPVRSHAPGLEARRLVE
IEQNILAKNDGFADTNRARLSTLGVFALNLLAGPGAGKTTLLVETLKALKDKIPAAVIEGDQQTSNDAERIRAVGAPAVQ
INTGKGCHLDAHMVGHALERLPLEAGGVLFIENVGNLVCPAAFDLGEDKRVTLLSVTEGEDKPLKYPDIFEGAHLVLLTK
ADLVPHLEVDVDLIIANVRRINPHAKVLTLSSRSGDGMRAWLSWLEDVRAEKLEALAEAAAARAAALRGAARRAAE
>Mature_316_residues
MCVTCGCGPDAVTISGPNGEAHHDPAHGHDHSHGHDHGHSHAHGDHGHGHHHHDDHHHGHDEPQPVRSHAPGLEARRLVE
IEQNILAKNDGFADTNRARLSTLGVFALNLLAGPGAGKTTLLVETLKALKDKIPAAVIEGDQQTSNDAERIRAVGAPAVQ
INTGKGCHLDAHMVGHALERLPLEAGGVLFIENVGNLVCPAAFDLGEDKRVTLLSVTEGEDKPLKYPDIFEGAHLVLLTK
ADLVPHLEVDVDLIIANVRRINPHAKVLTLSSRSGDGMRAWLSWLEDVRAEKLEALAEAAAARAAALRGAARRAAE

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=294, Percent_Identity=50.6802721088435, Blast_Score=297, Evalue=6e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 33696; Mature: 33696

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVTCGCGPDAVTISGPNGEAHHDPAHGHDHSHGHDHGHSHAHGDHGHGHHHHDDHHHGH
CEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEPQPVRSHAPGLEARRLVEIEQNILAKNDGFADTNRARLSTLGVFALNLLAGPGAGKTT
CCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
LLVETLKALKDKIPAAVIEGDQQTSNDAERIRAVGAPAVQINTGKGCHLDAHMVGHALER
HHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHH
LPLEAGGVLFIENVGNLVCPAAFDLGEDKRVTLLSVTEGEDKPLKYPDIFEGAHLVLLTK
CCCCCCCEEEEECCCCEECCHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEE
ADLVPHLEVDVDLIIANVRRINPHAKVLTLSSRSGDGMRAWLSWLEDVRAEKLEALAEAA
CCCCCCCCCCCEEEEEHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AARAAALRGAARRAAE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MCVTCGCGPDAVTISGPNGEAHHDPAHGHDHSHGHDHGHSHAHGDHGHGHHHHDDHHHGH
CEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEPQPVRSHAPGLEARRLVEIEQNILAKNDGFADTNRARLSTLGVFALNLLAGPGAGKTT
CCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHH
LLVETLKALKDKIPAAVIEGDQQTSNDAERIRAVGAPAVQINTGKGCHLDAHMVGHALER
HHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHH
LPLEAGGVLFIENVGNLVCPAAFDLGEDKRVTLLSVTEGEDKPLKYPDIFEGAHLVLLTK
CCCCCCCEEEEECCCCEECCHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEEE
ADLVPHLEVDVDLIIANVRRINPHAKVLTLSSRSGDGMRAWLSWLEDVRAEKLEALAEAA
CCCCCCCCCCCEEEEEHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AARAAALRGAARRAAE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]