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The map label for this gene is hypA

Identifier: 158422231

GI number: 158422231

Start: 673479

End: 673820

Strand: Direct

Name: hypA

Synonym: AZC_0607

Alternate gene names: 158422231

Gene position: 673479-673820 (Clockwise)

Preceding gene: 158422230

Following gene: 158422232

Centisome position: 12.54

GC content: 69.01

Gene sequence:

>342_bases
ATGCACGAAATGGCCATCTGCGAGAGCCTTCGGGTGTCCATGGAAGAGGCGGCACGGGCGCAGGATTTCTCCCGCGTCAC
GCGGGTGCGCCTCGCCATCGGCGCCTTCGCGGGCGTCGAGGTGGAAGCACTGCGCTTCGGCTTCGACGTCGTGATGCAGG
GCTCGCTGGCCGAGGGCGCGGAACTGGTGGTGCTGGAAGAGGAGGGCACCGCCTGGTGCTTCGACTGCAACCGCACGGTG
CCGCTCGCCACCCGCCTCGACCCCTGCCCCTGCTGCGGCGGCGAGCGCCTCGTGCCCAATGGCGGCACGGGCATGACCAT
CAAGGATCTGGAGGTGGTGTGA

Upstream 100 bases:

>100_bases
CCTTGCCGTCGCGCGCCGAGACGCCGATGCTGGGCCGCCTCGCGCTCCTCGCGGTCAATCCCTGCGTGCCGGTGAAGCTA
GAGGGGCTGGGGGGCTGACC

Downstream 100 bases:

>100_bases
TGTGCGTGACCTGCGGCTGCGGCCCTGATGCCGTGACCATCTCCGGCCCGAATGGCGAAGCGCATCACGATCCTGCGCAC
GGCCATGACCATTCTCACGG

Product: hydrogenase expression/synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMAICESLRVSMEEAARAQDFSRVTRVRLAIGAFAGVEVEALRFGFDVVMQGSLAEGAELVVLEEEGTAWCFDCNRTV
PLATRLDPCPCCGGERLVPNGGTGMTIKDLEVV

Sequences:

>Translated_113_residues
MHEMAICESLRVSMEEAARAQDFSRVTRVRLAIGAFAGVEVEALRFGFDVVMQGSLAEGAELVVLEEEGTAWCFDCNRTV
PLATRLDPCPCCGGERLVPNGGTGMTIKDLEVV
>Mature_113_residues
MHEMAICESLRVSMEEAARAQDFSRVTRVRLAIGAFAGVEVEALRFGFDVVMQGSLAEGAELVVLEEEGTAWCFDCNRTV
PLATRLDPCPCCGGERLVPNGGTGMTIKDLEVV

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=38.3928571428571, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=39.8230088495575, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_AZOC5 (A8IMT6)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001523523.1
- GeneID:   5690117
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_0607
- HOGENOM:   HBG688671
- OMA:   CFELVCR
- ProtClustDB:   CLSK979690
- BioCyc:   ACAU438753:AZC_0607-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12208; Mature: 12208

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
9.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMAICESLRVSMEEAARAQDFSRVTRVRLAIGAFAGVEVEALRFGFDVVMQGSLAEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECEEEEEECCCCCCE
ELVVLEEEGTAWCFDCNRTVPLATRLDPCPCCGGERLVPNGGTGMTIKDLEVV
EEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEEC
>Mature Secondary Structure
MHEMAICESLRVSMEEAARAQDFSRVTRVRLAIGAFAGVEVEALRFGFDVVMQGSLAEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECEEEEEECCCCCCE
ELVVLEEEGTAWCFDCNRTVPLATRLDPCPCCGGERLVPNGGTGMTIKDLEVV
EEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA