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The map label for this gene is gpmA

Identifier: 158421780

GI number: 158421780

Start: 186764

End: 187384

Strand: Reverse

Name: gpmA

Synonym: AZC_0156

Alternate gene names: 158421780

Gene position: 187384-186764 (Counterclockwise)

Preceding gene: 158421781

Following gene: 158421775

Centisome position: 3.49

GC content: 68.12

Gene sequence:

>621_bases
ATGGACCGGCTTCTCGTCCTCGTCCGTCATGGACAGAGCGAGTGGAATCTCAAGAACCTCTTCACCGGCTGGCGTGACCC
GAACCTGACCGATCAGGGCGTCAGCGAAGCCCGCCGCGCCGGCGCGCTGCTCGCCGCCGAGGGCCTGAGCTTCGACGTGG
CCTATACCTCGGCCCTCACCCGCGCCCAGCGCACCTGCCAGCTGGTGCTGGAGGAAATGGGCCTCACCGGCCTCAGGACC
ATCGCCGACCAAGCGCTGAACGAGCGCGATTACGGCGATCTCTCCGGCCTCAACAAGGACGATGCCCGCGCCAAGTTCGG
CGAGGAGCAGGTGCATGTGTGGCGCCGTTCCTATGACATCTCCCCGCCCGGCGGCGAGAGCCTGCGCGACACGGTCGCCC
GCGTGCTGCCCTATTTCGTGCAGGAGATCCTGCCGAGCGTGCTGCGCGGCGAGCGCACGCTGGTGGCGGCGCACGGTAAT
TCCCTGCGCGCGCTGGTGATGGTGCTGGAGCGTCTGTCGCCGGAAGGCATCATGAAGCGCGAGCTCGCCACCGGCGCGCC
CATCCTCTACCGCCTCGGCGCCGATGCGACCGTGAGCGAGAAGCGGGACATCCTGATCTGA

Upstream 100 bases:

>100_bases
TTGAGTTTTCCGGCGGCGTCCTATATGTCTCGCGTGCATTCCGATCGCGGCCCGGCGGCCTCAGCCGCCGCGGACCCGCC
AGCCACGCAAGGACATTCCT

Downstream 100 bases:

>100_bases
GCGTTTCCGACGATCGGTCGGAGCATGGAACGGGGCCGGCGCGACCGGCCCCTTTTTATTGCGTCAGCGCGGGCGCGGCA
CGGCGGTGGAGGCCACCGCC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MDRLLVLVRHGQSEWNLKNLFTGWRDPNLTDQGVSEARRAGALLAAEGLSFDVAYTSALTRAQRTCQLVLEEMGLTGLRT
IADQALNERDYGDLSGLNKDDARAKFGEEQVHVWRRSYDISPPGGESLRDTVARVLPYFVQEILPSVLRGERTLVAAHGN
SLRALVMVLERLSPEGIMKRELATGAPILYRLGADATVSEKRDILI

Sequences:

>Translated_206_residues
MDRLLVLVRHGQSEWNLKNLFTGWRDPNLTDQGVSEARRAGALLAAEGLSFDVAYTSALTRAQRTCQLVLEEMGLTGLRT
IADQALNERDYGDLSGLNKDDARAKFGEEQVHVWRRSYDISPPGGESLRDTVARVLPYFVQEILPSVLRGERTLVAAHGN
SLRALVMVLERLSPEGIMKRELATGAPILYRLGADATVSEKRDILI
>Mature_206_residues
MDRLLVLVRHGQSEWNLKNLFTGWRDPNLTDQGVSEARRAGALLAAEGLSFDVAYTSALTRAQRTCQLVLEEMGLTGLRT
IADQALNERDYGDLSGLNKDDARAKFGEEQVHVWRRSYDISPPGGESLRDTVARVLPYFVQEILPSVLRGERTLVAAHGN
SLRALVMVLERLSPEGIMKRELATGAPILYRLGADATVSEKRDILI

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI4505753, Length=215, Percent_Identity=45.1162790697674, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI50593010, Length=218, Percent_Identity=42.6605504587156, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI71274132, Length=215, Percent_Identity=42.3255813953488, Blast_Score=167, Evalue=7e-42,
Organism=Homo sapiens, GI4502445, Length=220, Percent_Identity=39.5454545454545, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI40353764, Length=220, Percent_Identity=39.5454545454545, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=42.5, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1786970, Length=213, Percent_Identity=45.5399061032864, Blast_Score=182, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6322697, Length=221, Percent_Identity=41.1764705882353, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324516, Length=264, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324857, Length=172, Percent_Identity=28.4883720930233, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646216, Length=216, Percent_Identity=43.0555555555556, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI85725270, Length=216, Percent_Identity=43.9814814814815, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI85725272, Length=216, Percent_Identity=43.9814814814815, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24650981, Length=216, Percent_Identity=43.9814814814815, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI28571817, Length=217, Percent_Identity=35.4838709677419, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28571815, Length=217, Percent_Identity=35.4838709677419, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24648979, Length=217, Percent_Identity=35.4838709677419, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_AZOC5 (A8IGZ9)

Other databases:

- EMBL:   AP009384
- RefSeq:   YP_001523072.1
- ProteinModelPortal:   A8IGZ9
- SMR:   A8IGZ9
- GeneID:   5691410
- GenomeReviews:   AP009384_GR
- KEGG:   azc:AZC_0156
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK01295
- BioCyc:   ACAU438753:AZC_0156-MONOMER
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 22858; Mature: 22858

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 10-10 ACT_SITE 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLLVLVRHGQSEWNLKNLFTGWRDPNLTDQGVSEARRAGALLAAEGLSFDVAYTSALT
CCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCHHEECCCEEHHHHHHHHH
RAQRTCQLVLEEMGLTGLRTIADQALNERDYGDLSGLNKDDARAKFGEEQVHVWRRSYDI
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCC
SPPGGESLRDTVARVLPYFVQEILPSVLRGERTLVAAHGNSLRALVMVLERLSPEGIMKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHH
ELATGAPILYRLGADATVSEKRDILI
HHHCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MDRLLVLVRHGQSEWNLKNLFTGWRDPNLTDQGVSEARRAGALLAAEGLSFDVAYTSALT
CCCEEEEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCHHEECCCEEHHHHHHHHH
RAQRTCQLVLEEMGLTGLRTIADQALNERDYGDLSGLNKDDARAKFGEEQVHVWRRSYDI
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCC
SPPGGESLRDTVARVLPYFVQEILPSVLRGERTLVAAHGNSLRALVMVLERLSPEGIMKR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHH
ELATGAPILYRLGADATVSEKRDILI
HHHCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA